Analysis of N- and O-Linked Glycosylation: Differential Glycosylation after Rat Spinal Cord Injury.

abstract：:Recent calls have been made for the inclusion of health-related quality of life (HRQoL) in traumatic brain injury studies. This study reports the impact of TBI on traditional measures (general health, depression, social isolation, labor force participation), self-assessed health function status using the SF-36 version...

journal_title：Journal of neurotrauma

authors： Hawthorne G,Gruen RL,Kaye AH

更新日期：2009-10-01 00:00:00

abstract：:The development of anxiety disorders after a traumatic brain injury (TBI) is a strong predictor of social, personal, and work dysfunction; nevertheless, the emergence of anxiety has been largely unexplored and poorly understood in the context of TBI. This article provides an overview of the limited published research ...

journal_title：Journal of neurotrauma

authors： Mallya S,Sutherland J,Pongracic S,Mainland B,Ornstein TJ

更新日期：2015-04-01 00:00:00

abstract：:Patients with head injury must overcome central as well as peripheral metabolic insults. In addition to specific tissue damage to the brain, a cellular biochemical cascade occurs that can negatively affect organ function, cause a systemic response to injury, and may cause secondary tissue injury. The metabolites invol...

journal_title：Journal of neurotrauma

authors： Ott L,McClain CJ,Gillespie M,Young B

更新日期：1994-10-01 00:00:00

abstract：:Researchers studying the impact of treatments designed to facilitate recovery after neural injury face competing demands. On the one hand, because treatment effects often emerge slowly over days, and because researchers seek evidence of stable long-term effects, it is common practice to observe experimental subjects f...

journal_title：Journal of neurotrauma

authors： Hook MA,Ferguson AR,Garcia G,Washburn SN,Koehly LM,Grau JW

更新日期：2004-01-01 00:00:00

abstract：:To compare the effect of levodopa-carbidopa on the visual outcome of patients with indirect traumatic optic neuropathy (ITON), this randomized, double-blind, placebo-controlled study was conducted on 32 patients with ITON within 6 days after trauma. Patients underwent a complete ocular examination, pattern visual evok...

journal_title：Journal of neurotrauma

authors： Razeghinejad MR,Rahat F,Bagheri M

更新日期：2010-10-01 00:00:00

abstract：:End-to-side neurorrhaphy is widely used in the peripheral nervous system for nerve repair; however, the application of this technique has been limited to somatic nerves. The feasibility of nerve regeneration through end-to-side neurorrhaphy between autonomic and somatic nerves with different characteristics in the per...

journal_title：Journal of neurotrauma

authors： Gao WS,Dong CJ,Li SQ,Kunwar KJ,Li B

更新日期：2012-05-20 00:00:00

abstract：:Symptoms persisting beyond the acute phase (>2 months) after a mild traumatic brain injury (MTBI) are often reported, but their origin remains controversial. Some investigators evoke dysfunctional cerebral mechanisms, while others ascribe them to the psychological consequences of the injury. We address this controvers...

journal_title：Journal of neurotrauma

authors： Gosselin N,Bottari C,Chen JK,Petrides M,Tinawi S,de Guise E,Ptito A

更新日期：2011-03-01 00:00:00

abstract：:Mild traumatic brain injury (mTBI) disrupts hippocampal function and can lead to long-lasting episodic memory impairments. The encoding of episodic memories relies on spatial information processing within the hippocampus. As the primary entry point for spatial information into the hippocampus, the dentate gyrus is tho...

journal_title：Journal of neurotrauma

authors： Folweiler KA,Samuel S,Metheny HE,Cohen AS

更新日期：2018-06-01 00:00:00

abstract：:Spinal cord injury (SCI) results in marked atrophy and dysfunction of skeletal muscle. There are currently no effective treatments for SCI-induced muscle atrophy or the dysfunction of the remaining muscle tissue. Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase-4 (Nox4) produces reactive oxygen species (ROS...

journal_title：Journal of neurotrauma

authors： Liu XH,Harlow L,Graham ZA,Bauman WA,Cardozo C

更新日期：2017-06-15 00:00:00

abstract：:Prognostic biomarkers for post-injury outcome are necessary for the development of neuroprotective and antiepileptogenic treatments for traumatic brain injury (TBI). We hypothesized that T2 relaxation magnetic resonance imaging (MRI) predicts the progression of perilesional cortical pathology and epileptogenesis. The ...

journal_title：Journal of neurotrauma

authors： Manninen E,Chary K,Lapinlampi N,Andrade P,Paananen T,Sierra A,Tohka J,Gröhn O,Pitkänen A

更新日期：2020-12-01 00:00:00

abstract：:The serum phosphorylated neurofilament heavy subunit (pNF-H) is a nervous system-specific protein that is released from damaged neural tissue after traumatic brain injury (TBI). The aim of this study was to elucidate the usefulness of serum pNF-H as a predictive marker for the outcome of patients after TBI. Patients w...

journal_title：Journal of neurotrauma

authors： Shibahashi K,Doi T,Tanaka S,Hoda H,Chikuda H,Sawada Y,Takasu Y,Chiba K,Nozaki T,Hamabe Y,Ogata T

更新日期：2016-10-15 00:00:00

abstract：:Blast injury to the brain is one of the major causes of death and can also significantly affect cognition and physical and psychological skills in survivors of blast. The complex mechanisms via which blast injury causes impairment of cognition and other symptoms are poorly understood. In this study, we investigated th...

journal_title：Journal of neurotrauma

authors： Lu J,Ng KC,Ling G,Wu J,Poon DJ,Kan EM,Tan MH,Wu YJ,Li P,Moochhala S,Yap E,Lee LK,Teo M,Yeh IB,Sergio DM,Chua F,Kumar SD,Ling EA

更新日期：2012-05-01 00:00:00

abstract：:Posttraumatic ischemia appears to be largely responsible for the extension of lesions in acute injury of the spinal cord. In the present study, we have evaluated the putative improvement of axonal function by the calcium channel blocker nimodipine after acute trauma of the spinal cord. Three techniques were used: (1) ...

journal_title：Journal of neurotrauma

authors： Pointillart V,Gense D,Gross C,Bidabé AM,Gin AM,Rivel J,Caillé JM,Sénégas J

更新日期：1993-07-01 00:00:00

abstract：:Diffusion tensor imaging (DTI) has demonstrated success as a biomarker of spinal cord injury (SCI) severity as shown from numerous pre-clinical studies. However, artifacts from stabilization hardware at the lesion have precluded its use for longitudinal assessments. Previous research has documented ex vivo diffusion c...

journal_title：Journal of neurotrauma

authors： Motovylyak A,Skinner NP,Schmit BD,Wilkins N,Kurpad SN,Budde MD

更新日期：2019-05-01 00:00:00

abstract：:Mild traumatic brain injury (mTBI) patients frequently experience emotion dysregulation symptoms, including post-traumatic stress. Although mTBI likely affects cortical activation and structure, resulting in cognitive symptoms after mTBI, early effects of mTBI on cortical emotion processing circuits have rarely been e...

journal_title：Journal of neurotrauma

authors： Wang X,Xie H,Cotton AS,Brickman KR,Lewis TJ,Wall JT,Tamburrino MB,Bauer WR,Law K,McLean SA,Liberzon I

更新日期：2017-01-15 00:00:00

abstract：:The lack of effective therapies for moderate-to-severe traumatic brain injuries (TBIs) leaves patients with lifelong disabilities. Neural stem cells (NSCs) have demonstrated great promise for neural repair and regeneration. However, direct evidence to support their use as a cell replacement therapy for neural injuries...

journal_title：Journal of neurotrauma

authors： Sun MK,Passaro AP,Latchoumane CF,Spellicy SE,Bowler M,Goeden M,Martin WJ,Holmes PV,Stice SL,Karumbaiah L

更新日期：2020-06-01 00:00:00

abstract：:Glial cell line-derived neurotrophic factor (GDNF) has been shown to protect cranial and spinal motoneurons, which suggests potential uses of GDNF in the treatment of spinal cord injury (SCI) and motor neuron disease. We examined neuroprotective effect of cationic liposome-mediated GDNF gene transfer in vivo on axonal...

journal_title：Journal of neurotrauma

authors： Lu KW,Chen ZY,Jin DD,Hou TS,Cao L,Fu Q

更新日期：2002-09-01 00:00:00

abstract：:Return to living at home is an important patient-reported outcome following traumatic spinal cord injury (tSCI). Specialized inpatient rehabilitation assists such patients in maximizing function and independence. Our project aim was to describe those patients receiving specialized rehabilitation after tSCI in Canada, ...

journal_title：Journal of neurotrauma

authors： Cheng CL,Plashkes T,Shen T,Fallah N,Humphreys S,O'Connell C,Linassi AG,Ho C,Short C,Ethans K,Charbonneau R,Paquet J,Noonan VK

更新日期：2017-10-15 00:00:00

abstract：:The efficacy of end-to-side repair as a method of nerve reconstruction has been questioned, and most studies that characterize the mode of re-innervation are marred by inappropriate experimental design and lack quantitative analysis. This makes characterization of re-innervating neurons confusing and consequently cont...

journal_title：Journal of neurotrauma

authors： Sananpanich K,Galea MP,Morrison WA,Messina A

更新日期：2007-05-01 00:00:00

abstract：:Wars in Afghanistan and Iraq have resulted in thousands of military personnel suffering traumatic brain injury (TBI), including closed-head injuries. Of interest is whether these individuals and other TBI survivors are at increased risk for substance use disorder (SUD). While it has been well established that drug or ...

journal_title：Journal of neurotrauma

authors： Bjork JM,Grant SJ

更新日期：2009-07-01 00:00:00

abstract：:Alterations in glutamatergic transmission are thought to contribute to secondary neuronal damage following traumatic brain injury. Using an in vitro cell injury model, we previously demonstrated an apparent reduction in AMPA receptor desensitization and resultant potentiation of AMPA-evoked currents after stretch inju...

journal_title：Journal of neurotrauma

authors： Goforth PB,Ellis EF,Satin LS

更新日期：2004-06-01 00:00:00

abstract：:Current thinking views mild head impact (i.e., subconcussion) as an underrecognized phenomenon that has the ability to cause significant current and future detrimental neurological effects. Repeated mild impacts to the head, however, often display no observable behavioral deficits based on standard clinical tests, whi...

journal_title：Journal of neurotrauma

authors： Hwang S,Ma L,Kawata K,Tierney R,Jeka JJ

更新日期：2017-01-01 00:00:00

abstract：:Pairing vagus nerve stimulation (VNS) with rehabilitation has emerged as a potential strategy to enhance plasticity and improve recovery in a range of neurological disorders. A recent study highlights the therapeutic promise of VNS in promoting motor recovery after spinal cord injury (SCI). We investigated the safety ...

journal_title：Journal of neurotrauma

authors： Sachdeva R,Krassioukov AV,Bucksot JE,Hays SA

更新日期：2020-05-01 00:00:00

abstract：:Muscle strength was assessed from the maximum force that could be exerted voluntarily by triceps brachii muscles of 72 people with chronic cervical spinal cord injury (SCI) at or above C7, and 18 able-bodied (A-B) subjects. The magnitude of co-activation was estimated from the ratio of biceps brachii surface EMG to tr...

journal_title：Journal of neurotrauma

authors： Thomas CK,Tucker ME,Bigland-Ritchie B

更新日期：1998-02-01 00:00:00

abstract：:Traumatic axonal injury (TAI) is a critical public health issue with its pathogenesis remaining largely elusive. Finite element (FE) head models are promising tools to bridge the gap between mechanical insult, localized brain response, and resultant injury. In particular, the FE-derived deformation along the direction...

journal_title：Journal of neurotrauma

authors： Zhou Z,Domel AG,Li X,Grant G,Kleiven S,Camarillo DB,Zeineh M

更新日期：2021-01-15 00:00:00

abstract：:Assessment of acute mild traumatic brain injury (mTBI) symptoms after a combat blast could aid diagnosis and guide follow-up care. Our objective was to document acute mTBI symptoms following a combat blast and to examine associations between acute symptoms and mental health and service discharge outcomes. A retrospect...

journal_title：Journal of neurotrauma

authors： Eskridge SL,Macera CA,Galarneau MR,Holbrook TL,Woodruff SI,MacGregor AJ,Morton DJ,Shaffer RA

更新日期：2013-08-15 00:00:00

abstract：:A critical component for accelerating the clinical uptake of research data in the area of pediatric concussion or mild traumatic brain injury (MTBI) pertains to the establishment and utilization of common databases. The objective of the first phase of our CanPedCDE initiative was to agree upon pediatric common data el...

journal_title：Journal of neurotrauma

authors： Gagnon I,Friedman D,Beauchamp MH,Christie B,DeMatteo C,Macartney G,McFadyen BJ,Sirois K,Taneja C,Zabjek K,Zemek R,Mrazik M

更新日期：2018-08-15 00:00:00

abstract：:After a severe, high-level spinal cord injury (SCI), plasticity to intraspinal circuits below injury results in heightened spinal sympathetic reflex activity and detrimentally impacts peripheral organ systems. Such sympathetic hyperreflexia is immediately apparent as an episode of autonomic dysreflexia (AD), a life-th...

journal_title：Journal of neurotrauma

authors： O'Reilly M,Mironets E,Saltos T,Crowther K,Collyer E,Bethea J,Tom VJ

更新日期：2021-01-04 00:00:00

abstract：:Patients sustaining severe traumatic brain injury (TBI) have variable long-term outcomes. We examined the association between Glasgow Outcome Scale (GOS) assessed at 3 months and long-term outcomes at 12 months after TBI. We studied 159 patients with severe, closed traumatic brain injuries (Glasgow Coma Scale [GCS]

journal_title：Journal of neurotrauma

authors： King JT Jr,Carlier PM,Marion DW

更新日期：2005-09-01 00:00:00

abstract：:Using diffusion tensor imaging (DTI), we assessed the relationship of white matter integrity and performance on the Boston Naming Test (BNT) in a group of retired professional football players and a control group. We examined correlations between fractional anisotropy (FA) and mean diffusivity (MD) with BNT T-scores i...

journal_title：Journal of neurotrauma

authors： Strain JF,Didehbani N,Spence J,Conover H,Bartz EK,Mansinghani S,Jeroudi MK,Rao NK,Fields LM,Kraut MA,Cullum CM,Hart J Jr,Womack KB

更新日期：2017-01-15 00:00:00