Abstract:
:In a controlled study, it has been shown that the prior administration of cholera vaccine had no beneficial effect on the clinical course of cholera as measured by either the condition of the patient on admission to hospital or the subsequent course of the disease. In fact, the disease was, if anything, more severe in those who had received cholera vaccine. Although the presence of a high vibriocidal titre is associated with protection from cholera, pre-existing antibody had no effect on the clinical course of the disease in those patients who developed cholera.
journal_name
Bull World Health Organjournal_title
Bulletin of the World Health Organizationauthors
McCormack WM,Rahman AS,Chowdhury AK,Mosley WH,Phillips RAsubject
Has Abstractpub_date
1969-01-01 00:00:00pages
199-204issue
2eissn
0042-9686issn
1564-0604journal_volume
40pub_type
杂志文章abstract::From the standpoint of nutritional needs, physiological maturation, and immunological safety the provision of foods other than breast milk before about four months of age is unnecessary and may also be harmful. On the other hand, many infants require some complementary feeding by about six months of age. There are a n...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::While an earlier live measles vaccine induced a high degree of immunity it also caused clinical reactions of variable severity in some vaccinated children. A number of attenuated measles vaccine strains have been developed to avoid these problems, and this paper reports the results of small-scale trials with 3 attenua...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1968-01-01 00:00:00
abstract::Post-vaccination tuberculin sensitivity is being used to evaluate the immediate effects of the extensive WHO/UNICEF mass BCG vaccination programmes currently in progress. During the past five years the Tuberculosis Research Office has been studying the tuberculin sensitivity produced by BCG vaccination, and the presen...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1955-01-01 00:00:00
abstract::Sexually transmitted diseases (STD) are now the commonest group of notifiable infectious diseases in most countries, particularly in the age group of 15 to 50 years and in infants. Their control is important considering the high incidence of acute infections, complications and sequelae, their socioeconomic impact, and...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:
更新日期:1990-01-01 00:00:00
abstract::A form of endemic syphilis exists in the Bakwena Reserve of the Bechuanaland Protectorate known by the local name of "dichuchwa". It is similar to bejel, njovera and the endemic syphilis reported elsewhere in the world. The Government of the Protectorate, with the assistance of WHO and UNICEF, began in November 1953 a...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1956-01-01 00:00:00
abstract::Health interventions vary substantially in the degree of effort required to implement them. To some extent this is apparent in their financial cost, but the nature and availability of non-financial resources is often of similar importance. In particular, human resource requirements are frequently a major constraint. W...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:/S0042-96862005000400013
更新日期:2005-04-01 00:00:00
abstract::Pretreatment cultures of bacilli from Indian patients with active pulmonary tuberculosis admitted to a controlled domiciliary chemotherapy study by the Tuberculosis Chemotherapy Centre, Madras, were subjected to a series of in vitro tests designed to identify the bacilli as human or bovine tubercle bacilli, or as anon...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1961-01-01 00:00:00
abstract::There is considerable exigency to take all necessary steps to cure tuberculosis cases and prevent further emergence of drug-resistant tuberculosis. The most important of these steps is to ensure that the treatment, particularly of sputum smear-positive cases, is adequate and that patients adhere to their treatment by ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2001-01-01 00:00:00
abstract::Single-radial-diffusion techniques are proposed as possible alternatives to tests based on agglutination of erythrocytes for the assay of the haemagglutinin content of influenza vaccines. Two test procedures (microtest and macrotest) and the use of reference reagents to assay vaccines using these tests are described. ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract::This paper gives a comprehensive account of the first six years of operation of an onchocerciasis control pilot project in an area of over 3000 km(2) in the Abuja Emirate, Northern Nigeria. Control was attempted by the use of DDT against the larvae of the vector, Simulium damnosum. For the first two years technical DD...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1962-01-01 00:00:00
abstract::Genomics, the comprehensive examination of an organism's entire set of genes and their interactions, will have a major impact on the way disease is diagnosed, prevented and treated in the new millennium. Despite the tremendous potential it holds for improving global health, genomics challenges policy-makers to ensure ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2004-05-01 00:00:00
abstract:OBJECTIVE:To assess the effectiveness of decentralized treatment and care for patients with multidrug-resistant (MDR) tuberculosis, in comparison with centralized approaches. METHODS:We searched ClinicalTrials.gov, the Cochrane library, Embase®, Google Scholar, LILACS, PubMed®, Web of Science and the World Health Orga...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,meta分析,评审
doi:10.2471/BLT.17.193375
更新日期:2017-08-01 00:00:00
abstract::The authors have attempted to prepare lysed BCG vaccines retaining the protective antigens of the BCG cell wall and yet eliciting in experimental animals limited sensitivity to the tuberculin substances, the advantage sought being to retain the usefulness of the tuberculin following vaccination as an indicator of supe...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1967-01-01 00:00:00
abstract::The author reviews the published findings on the carriage of Staphylococcus pyogenes var. aureus during the last two decades, dealing mainly with observations made in British Commonwealth countries, Scandinavia and the USA. The importance of the role played by staphylococcal carriers in the spread of infection both in...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1961-01-01 00:00:00
abstract::Epidemics of presumed arthropod-borne virus infections have occurred over the years in the Australasian region but as yet little is known about the identity, distribution and frequency of occurrence of the viruses present. Therefore, beginning with specimens collected in 1956, a systematic sero-epidemiological study w...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1964-01-01 00:00:00
abstract::The public sector in developing countries is increasingly contracting with the non-state sector to improve access, efficiency and quality of health services. We conducted a multicountry study to assess the range of health services contracted out, the process of contracting and its influencing factors in ten countries ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/blt.06.033027
更新日期:2006-11-01 00:00:00
abstract::Cholera, which had been spreading throughout the south-west Pacific in 1961, broke out in Hong Kong in August of that year. The outbreak lasted about six weeks, and recurred in 1962 and 1963; but whereas the 1961 outbreak resembled classical cholera, in the succeeding years the pattern changed. The disease, though sti...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1965-01-01 00:00:00
abstract::A case-control study was conducted in Yaoundé, United Republic of Cameroon, to evaluate the hypothesis that intramuscular inoculations predisposed young children to paralysis if they were later exposed to poliomyelitis virus. Thirty-three cases with lower motor neuron disease and 66 neighbourhood controls were studied...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1980-01-01 00:00:00
abstract::To study the association of meningococcal serogroups with the course of disease, we reviewed the case histories of 1221 patients. The meningococci from these patients constituted a sample from isolates collected and serogrouped systematically in the Netherlands since 1959. Of these 1221 isolates, 64% were serogroup B....
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1987-01-01 00:00:00
abstract:OBJECTIVE:To investigate the impact of violence against mothers on mortality risks for their offspring before 5 years of age in Nicaragua. METHODS:From a demographic database covering a random sample of urban and rural households in Le n, Nicaragua, we identified all live births among women aged 15-49 years. Cases wer...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:To determine trends in mortality from respiratory disease in several areas of Latin America between 1998 and 2009. METHODS:The numbers of deaths attributed to respiratory disease between 1998 and 2009 were extracted from mortality data from Argentina, southern Brazil, Chile, Costa Rica, Ecuador, Mexico and P...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.12.116871
更新日期:2013-07-01 00:00:00
abstract::N-Tritylmorpholine (Frescon, WL 8008) is highly toxic to the intermediate-host snails of the Schistosomatidae. Molluscicidal concentrations range from 0.1 ppm to 0.5 ppm for 1-hour exposures and from 0.01 ppm to 0.05 ppm for 24-hour exposures. Under these conditions the compound is not toxic to snail eggs; recent work...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1967-01-01 00:00:00
abstract::The immunological characteristics of 26 strains of Japanese encephalitis virus (JEV) isolated in Japan and Malaya between 1935 and 1966 have been investigated mainly by the antibody-absorption variant of the haemagglutination-inhibition test, and to a certain extent also by conventional haemagglutination-inhibition an...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1968-01-01 00:00:00
abstract::Bladder cancer is the twelfth most common cancer globally, with approximately 170 000 new cases each year; a third of these cases are in the developing countries. There are two major etiological types. The first is more common in the industrialized countries and is associated with exposure to certain occupational and ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章,评审
doi:
更新日期:1987-01-01 00:00:00
abstract::Registration of births, recording deaths by age, sex and cause, and calculating mortality levels and differentials are fundamental to evidence-based health policy, monitoring and evaluation. Yet few of the countries with the greatest need for these data have functioning systems to produce them despite legislation prov...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:/S0042-96862005000800015
更新日期:2005-08-01 00:00:00
abstract::The sensitivity of Plasmodium falciparum strains to chloroquine was tested in one locality in the north-east of the United Republic of Tanzania, where a chloroquine-medicated salt project has been implemented for chemosuppression for many years, and where large amounts of the drug have been available during the last d...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::The use of BCG vaccine in the prevention of leprosy has been one of the most important subjects of investigation in the field of leprology in the last 25 years. The action of the vaccine was for many years investigated by determining its effect on the lepromin reaction. Field studies were later considered essential to...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1970-01-01 00:00:00
abstract::The third study in a series on the prevalence of non-tuberculosis mycobacteria in Africa is devoted to the investigation of the formamidase activity of 288 cultures of mycobacteria, already typed by a battery of standard tests as pathogenic or atypical (184 strains) and saprophytic (104 strains). Of the latter, 96 (92...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1967-01-01 00:00:00
abstract::Two, 30-cluster, retrospective surveys of deaths from neonatal tetanus in Indonesia were conducted during 1982. The first survey, in the city of Jakarta, identified 16 deaths from neonatal tetanus among 2310 live births, giving a mortality rate of 6.9 per 1000 live births. The second survey covered 19 of Indonesia's 2...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract:OBJECTIVE:To evaluate the potential effects of betel quid chewing on mortality. (A quid consists of betel nut, wrapped in betel leaves; tobacco is added to the quid by some users). METHODS:Prospective data were available on 20 033 individuals aged 18-75 years, living in Araihazar, Bangladesh. Demographic and exposure ...
journal_title:Bulletin of the World Health Organization
pub_type: 杂志文章
doi:10.2471/BLT.14.149484
更新日期:2015-10-01 00:00:00