Abstract:
:The effects of injections of M- and N-cholinergic blocking agents into the antero-medial hypothalamus (HM) and the midbrain central gray (GC) on the aggressive behavior of cats, evoked by microinjections of carbachol into those areas, were investigated in chronic experiments. The influence of pharmacological suppression of the M-cholinergic system in HM on the carbachol-induced aggression response from GC and vice versa was also studied. In the experiments a quantitative method was applied for measuring the specific vocalization - growling, which is a characteristic of aggressive behavior. In the HM and GC areas of the cat the N- and the M-cholinergic systems participated in the control of aggressive behavior, but the M-component dominated in the process. The suppression of M-cholinergic system in GC prevented the appearance of aggressive behavior evoked by injections of carbachol into HM, and the M-cholinergic blockade in HM reduced (by 90 percent) the aggression response evoked by the injections of carbachol into GC. It is concluded that a concurrent action of the hypothalamic and the midbrain cholinergic systems is necessary for the appearance of a fully expressed aggressive behavior. The hypothalamus and the midbrain are probably links of the same functional circuit, and that the control of aggressive behavior is based on a circulatory action between these structures.
journal_name
Acta Neurobiol Exp (Wars)journal_title
Acta neurobiologiae experimentalisauthors
Romaniuk A,Golebiewski Hsubject
Has Abstractpub_date
1977-01-01 00:00:00pages
83-97issue
2eissn
0065-1400issn
1689-0035journal_volume
37pub_type
杂志文章abstract::The hippocampal EEG activity was recorded in male rats during the response-contingent reinforcement of a female. The instrumental response was a bar-pressing on a fixed-ratio-10 reinforcement schedule. The frequency of bar-pressing tends to increase during the succeeding copulatory series. The similar phenomenon was o...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::Thyroid hormones are essential for normal brain development and very important in the normal functioning of the brain. Thyroid hormones action in the adult brain has not been widely studied. The effects of adult hyperthyroidism are not as well understood as adult hypothyroidism, mainly in hippocampal granular cells. T...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract::This paper reviews studies that investigate conditions resulting in long-lasting modifications of synaptic efficacy in horizontal connections within layers II/III of adult rat motor cortex using the in vitro slice preparation. Long-term potentiation (LTP) was induced by high frequency theta burst stimulation (TBS) whe...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:1996-01-01 00:00:00
abstract::As investigation has been made of the adequacy of direct current to block conduction in the myelinated fibres of the cervical vagus nerve, leaving the nonmyelinated fibres conducting normally. Conduction was assessed from the compound electroneurograms, and from single fibre recording. Conduction of spontaneous activi...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1973-01-01 00:00:00
abstract::Studies were performed on 46 units of medial gastrocnemius muscles in 23 rats. In the examined population, three types of motor units were distinguished: fast fatigable (FF), fast resistant (FR) and slow (S) units. The studied muscle was stretched with force gradually increasing from 0.5 to 10 g. Most of FF units and ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1990-01-01 00:00:00
abstract::Cholinesterase inhibitors are currently the mainstream of symptomatic treatment of patients with Alzheimer's disease. The response to treatment with cholinesterase inhibitors is clinically difficult to predict. Several demographic, clinical and biological variables have been proposed as pretreatment predictors of long...
journal_title:Acta neurobiologiae experimentalis
pub_type: 临床试验,杂志文章
doi:
更新日期:2007-01-01 00:00:00
abstract::Cyto- and myeloarchitectonics as well as acetylcholinesterase activity of the nucleus limitans thalami--an important part of the nociceptive system--were studied in insectivora (Sorex araneus, Erinaceus europaeus, Talpa europaeus), rat, rabbit, cat, monkey and man. Our results suggest that nucleus limitans is phylogen...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1989-01-01 00:00:00
abstract::Disturbances of enteric nerve-mediated anorectal evacuation mechanisms have medical and social impact. The study aimed at further eliciting the contribution of cholinergic and nitrergic neurotransmission systems to modular nerve networks in different regions of Wistar rat anorectum. Electrical field stimulation (EFS, ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2012-01-01 00:00:00
abstract::The mammalian pineal organ contains photoreceptor-specific proteins, whose distribution shows conspicuous variation among different species of mammals. Nevertheless, the following general conclusions can be drawn: immunoreactions for S-antigen and recoverin labeled more pinealocytes than the rod-opsin immunoreaction. ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:1994-01-01 00:00:00
abstract::During luteolysis in sheep, episodic pulses of oxytocin (OT), contributed by the neurohypophysis and the corpus luteum (CL), stimulate uterine luteolytic pulses of prostaglandin (PG) F2 alpha via endometrial OT receptors. To distinguish relative contributions of neurohypophysial and luteal OT, ovariectomized sheep wer...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1996-01-01 00:00:00
abstract::The activity of the biceps brachii and lateral head of the triceps brachii were compared during the contact placing reactions elicited by tactile stimuli applied to the lateral, medial or dorsal aspects of the forepaw to verify the hypothesis that common movement strategy was used in all these reactions. Similar laten...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1993-01-01 00:00:00
abstract::In an effort to determine the plasticity of the proliferative matrix of the hippocampus in an adult rat to environmental manipulation, the following study was conducted. Fifteen adult male Long-Evans rats (6 months old at the start of the experiment) were placed into two different environments for 3 months. Seven anim...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1982-01-01 00:00:00
abstract::Food CSs, presented (i) concomitantly with SD controlling bar pressing for food, or (ii) on the background of non-discriminated bar pressing (FR 1/15), suppress instrumental performance but elicit undiminished conditioned salivation. This result supports Soltysik-Konorski's model of CNS mechanism controlling food-orie...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1976-01-01 00:00:00
abstract::The noble gas xenon (Xe) inhibits not only NMDA receptors (NMDARs) but also the two other subtypes of glutamate receptor i.e. AMPA (AMPARs) and kainate receptors. Preliminary studies on AMPARs suggest that Xe sensitivity might be coupled to receptor desensitization. In order to find out if this hypothesis can be appli...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2009-01-01 00:00:00
abstract::This study aimed to provide a simple way to approach group differences by independent component analysis when researching functional connectivity changes of resting-state network in brain disorders. We used baseline resting state functional magnetic resonance imaging from the Alzheimer's disease neuroimaging initiativ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:10.21307/ane-2017-028
更新日期:2016-01-01 00:00:00
abstract::Embedment-free electron microscopy (EFEM) is a new method which allows the visualisation of cytoskeleton in whole-mounted cells. In this study we employed EFEM to investigate the structure of cellular scaffolds in glioma C6 cell line. The cells were extracted with Triton X-100 that dissolves phospholipids in the membr...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2000-01-01 00:00:00
abstract::We report here the microglial (macrophage) and astrocytic reaction in several models of transmissible spongiform encephalopathies (TSEs) or prion diseases. With the low power electron microscopy it was readily apparent that myelinated vacuoles were surrounded by cells and their processes. The latter belonged either to...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::The aim of the study was to evaluate REM sleep parameters, especially the temporal characteristics of rapid eye movement activity, in depressed patients, and to compare three different methods for scoring of REM density. The sleep of 15 nonmedicated depressed patients and 13 healthy controls was recorded during two co...
journal_title:Acta neurobiologiae experimentalis
pub_type: 临床试验,杂志文章
doi:
更新日期:2002-01-01 00:00:00
abstract::The cortex of the middle suprasylvian sulcus was removed unilaterally in cats with brain stem transected at the pretrigeminal level. The vertical following reflex was evoked by a slit of light (1 degree x 4 degrees) moving along the vertical meridian or parallel to it up to 40 degrees in the left or right hemifield. T...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00
abstract::The purpose of this review is to summarize current knowledge about the gut microbiota in neuropsychiatric disorders. It is estimated that the human gut is colonized by up to 1018 microorganisms, mostly anaerobic bacteria. The gut microbiome is responsible for multiple functions, e.g. tightness of the intestine barrier...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章,评审
doi:
更新日期:2018-01-01 00:00:00
abstract::A review of recent anatomical evidence shows that every neocortical area and many nuclei from the dorsal thalamus project to restricted neostriatal regions. The neurobehavioral literature offers many examples of the same results obtained with lesions, stimulations or recordings in a neocortical area and the associated...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1972-01-01 00:00:00
abstract::It was found previously that unilateral destruction of the ventral tegmental area (VTA) facilitated behavioral responses (exploration, eating) induced by electrical stimulation of the contralateral VTA. The same effect occurred after unilateral injections of pharmacological agents, which led to a decrease in dopaminer...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2003-01-01 00:00:00
abstract::In the present study the functional role of SH groups in the Ca(2+)-independent K(+)-selective channel activity in the membrane of bovine adrenal gland chromaffin granules has been studied. Ionic channel activity has been estimated using 86Rb+, a K+ analogue, flux measurements. The inhibition of chromaffin granules K+...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1997-01-01 00:00:00
abstract::Mutations in the PINK1 gene are responsible for typical symptoms of Parkinson's disease. Using Drosophila melanogaster mutant PINK1B9 and after PINK1 silencing with RNAi using transgenic lines, we observed defects in synapses and behavior. The lack or reduced expression of PINK1 prolonged sleep during the day (nap) an...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2018-01-01 00:00:00
abstract::Leukemia inhibitory factor (LIF) is a neuroprotective cytokine that is necessary for the normal development of astrocytes. Oxygen-glucose deprivation (OGD) can induce astrocyte proliferation by increasing hypoxia-inducible factor alpha (HIF-1alpha) and vascular endothelial growth factor (VEGF). Here, we studied whethe...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2013-01-01 00:00:00
abstract::Fifteen laboratory born cats were used: seven binocularly deprived, four reared under condition of daily alternating monocular exposure and four controls. At the 7th month of age four of the binocularly deprived cats and all the remaining cats were trained monocularly in a two choice apparatus. In the first stage of t...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1986-01-01 00:00:00
abstract::The functions of the central monoamines Norepinephrine (NE) and Serotonin (5HT) can be clarified by the study of behaviors of rats administered selective monoamine toxins. In his home environment the low NE rat has drive deficits and is lethargic, tending to remain in his burrow, but in novel environments this animal ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract::Temporal information processing controls many aspects of human mental activity and may be assessed by examining perception of temporal order in the tens of milliseconds time range. Although existing studies suggest an age-related decline in mental abilities, the data on the deterioration of temporal order perception s...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:2008-01-01 00:00:00
abstract::We have studied MHC class II antigen expression and lymphocytic infiltration during dopaminergic neurone degeneration produced by intoxication with 1-methyl-4-phenyl-1,2,3,6-tetrahydropiridine (MPTP). Microglial activation was observed in the striatum and in the substantia nigra (SN) in this model. We noticed a marked...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1999-01-01 00:00:00
abstract::Twenty two months old and eight months old rats were used. They were submitted to object recognition test with 1 min interval between two successive presentations of the same object or two different objects. Initial exploration of the object was lower in aged than in young rats. However, both groups showed comparable ...
journal_title:Acta neurobiologiae experimentalis
pub_type: 杂志文章
doi:
更新日期:1994-01-01 00:00:00