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Hyperreactivity to myelin basic protein in multiple sclerosis.

Abstract：

:Multiple sclerosis patients, control patients with other neurological diseases, and normal volunteers were assayed in a short-term 51chromium release assay for cell-mediated cytotoxicity against lymphocyte targets coated with myelin basic protein. Multiple sclerosis patients, compared to the other two groups, were hyperreactive to myelin basic protein, both before and after in vitro boost with additional myelin basic protein. The boost served to augment the difference between multiple sclerosis patients and controls.

journal_name

J Neurol Sci

journal_title

Journal of the neurological sciences

authors

Eggers AE,Tarmin L,Plank CR,Gamboa ET

doi

10.1016/0022-510x(81)90019-8

subject

Has Abstract

pub_date

1981-11-01 00:00:00

pages

385-90

issue

2-3

eissn

0022-510X

issn

1878-5883

pii

0022-510X(81)90019-8

journal_volume

52

pub_type

杂志文章

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