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Involvement of legs and other body parts in patients with restless legs syndrome and its variants.

Abstract：

BACKGROUND:Restless legs syndrome (RLS) is characterized by the urge to move the legs accompanied by movement-responsive, abnormal sensations, which worsen at rest and night. We investigated the distribution of sensory symptoms and clinical correlations in patients with RLS and its variants. METHODS:Eighty-nine patients diagnosed with RLS or RLS variants (age 61.4 ± 18.5 years 40 M/49 F) according to established criteria, with the exclusion of those with augmentation, were included in this study. The international RLS rating scale (IRLS) was used to assess the severity of RLS/RLS variant symptoms. RESULTS:Eighty-three patients (93.3%) had RLS, and 6 patients (6.7%) had RLS variants. Among the patients with RLS and RLS variants, 33 patients (36.0%) reported restlessness involving other body parts: arms (16.9%) were the most frequent region, followed by the back (10.1%), abdomen (6.7%), and buttocks (4.5%). There were no between-group differences in clinical characteristics, except for the level of sleep disturbances being higher in patients with RLS variants (n=6) than in patients with RLS (n=83). No significant difference was observed in clinical characteristics including RLS severity and treatment between patients with RLS only (n=57) and patients with RLS with other body part involvement (n=26). No relationship was observed between the onset of symptoms in the legs and other body parts, but the IRLS scores for legs and other body parts were significantly correlated. CONCLUSION:We should recognize that RLS can involve not only legs but also other body parts to varying degrees in each patient.

journal_name

J Neurol Sci

journal_title

Journal of the neurological sciences

authors

Suzuki K,Suzuki S,Miyamoto M,Miyamoto T,Matsubara T,Nozawa N,Arikawa T,Nakajima I,Hirata K

doi

10.1016/j.jns.2019.116519

subject

Has Abstract

pub_date

2019-12-15 00:00:00

pages

116519

eissn

0022-510X

issn

1878-5883

pii

S0022-510X(19)30451-4

journal_volume

407

pub_type

杂志文章

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