Frontal-lobe syndrome and psychosis after damage to the brainstem dopaminergic nuclei.

Abstract:

:A patient developed frontal-lobe syndrome and psychotic symptoms after infarction in the pontomesencephalic junction. Stereotaxic lesion localization on magnetic resonance imaging and statistical analyses of regional cerebral blood flow (rCBF) disclosed an involvement of the rostral brainstem dopaminergic nuclei and hypoperfusion in the frontal-subcortical circuit components. We suggest that the patient's cognitive and behavioral disturbances were associated with disruption of ascending dopaminergic projections to the frontal-subcortical circuits.

journal_name

J Neurol Sci

authors

Nishio Y,Ishii K,Kazui H,Hosokai Y,Mori E

doi

10.1016/j.jns.2007.04.021

subject

Has Abstract

pub_date

2007-09-15 00:00:00

pages

271-4

issue

1-2

eissn

0022-510X

issn

1878-5883

pii

S0022-510X(07)00287-0

journal_volume

260

pub_type

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