Infarct presenting with a combination of Wallenberg and posterior spinal artery syndromes.

abstract：:The localization of the olivo-cerebellar fibers in the inferior cerebellar peduncle was examined in a patient who showed severe degeneration of the left olivary nucleus due to an old hemorrhagic infarct in the contralateral cerebellum. Other precerebellar nuclei which send their cerebellipetal axons to the inferior ce...

journal_title：Journal of the neurological sciences

authors： Iwata M,Hirano A

更新日期：1978-10-01 00:00:00

abstract：AIM:The balance of excitation and inhibition of neurons and neuronal network is very important to perform complete neuronal function. Damage or loss of inhibitory γ-aminobutyric acid (GABA)-ergic interneuron is associated with impaired inhibitory control of cortical pyramidal neurons, leading to hyperexcitability and e...

journal_title：Journal of the neurological sciences

authors： Sakakibara T,Sukigara S,Otsuki T,Takahashi A,Kaneko Y,Kaido T,Saito Y,Sato N,Nakagawa E,Sugai K,Sasaki M,Goto Y,Itoh M

更新日期：2012-12-15 00:00:00

abstract：:Forty-three patients with Parkinson's disease (PD) and thirty-seven normal volunteers were subjected to clinical, neuropsychological, neurophysiological (P300 component of the event-related potentials ERP) and radiological (cranial computerized tomographic scanning CCT) evaluation. Intentional memory was more impaired...

journal_title：Journal of the neurological sciences

authors： Elwan OH,Baradah OH,Madkour O,Elwan H,Hassan AA,Elwan F,Mahfouz M,Ali A,Fahmy M

更新日期：1996-11-01 00:00:00

abstract：:Thalamic damage is associated with a variety of neuropsychological dysfunctions, as well as strategic infarct dementia. However, only a limited number of reports in the medical literature have discussed the correlation between the clinical findings and the specific functional changes observed on images. We investigate...

journal_title：Journal of the neurological sciences

authors： Shim YS,Kim JS,Shon YM,Chung YA,Ahn KJ,Yang DW

更新日期：2008-03-15 00:00:00

abstract：:Observations have been made on the regeneration of myelinated fibres in the sural nerve of streptozotocin-induced diabetic rats and age-matched non-diabetic control animals at 3, 6 and 18 weeks after a localized crush lesion. Morphometric studies on the regenerated fibres revealed no differences in the total fibre cou...

journal_title：Journal of the neurological sciences

authors： Sharma AK,Thomas PK

更新日期：1975-04-01 00:00:00

abstract：:We assayed IL-6 in 105 cerebrospinal fluid (CSF) samples from patients with ALS, MS, HTLV-1 associated myelopathy (HAM), and controls. There was considerable overlap in IL-6 levels in all patient groups. The mean IL-6 in 27 patients with ALS was significantly higher than in 21 patients in the other neurological diseas...

journal_title：Journal of the neurological sciences

authors： Sekizawa T,Openshaw H,Ohbo K,Sugamura K,Itoyama Y,Niland JC

更新日期：1998-02-05 00:00:00

abstract：BACKGROUND:Myosin-IIB is a non-muscle isoform in the brain with increased expression in the brains of diabetic rats. Chronic hyperglycemia caused by diabetes can impair learning and memory. Oral hypoglycemic agents such as glibenclamide have been used to control hyperglycemia. We report changes in the expression and di...

journal_title：Journal of the neurological sciences

authors： da Costa AV,Calábria LK,de Souza Santos P,Goulart LR,Espindola FS

更新日期：2014-05-15 00:00:00

abstract：:Four of 8 definite heterozygous female carriers determined by PCR amplification of tandem CAG repeat of the AR gene, from 4 families of X-linked recessive bulbospinal neuronopathy (X-BSNP) showed extensive high amplitude motor unit potentials in examined muscles although all subjects were neurologically normal. Plasma...

journal_title：Journal of the neurological sciences

authors： Sobue G,Doyu M,Kachi T,Yasuda T,Mukai E,Kumagai T,Mitsuma T

更新日期：1993-07-01 00:00:00

abstract：:Water-suppressed proton magnetic resonance spectroscopy which has recently shown diagnostic potential in human stroke victims was performed in two patients who had suffered a hemispheric transient ischemic attack. Localized spectra were targeted from routine MR images. In one patient lactate could be observed 8 weeks ...

journal_title：Journal of the neurological sciences

authors： Felber S,Luef G,Aichner F

更新日期：1992-03-01 00:00:00

abstract：:A 70-year-old Japanese woman developed progressive, dopa-responsive parkinsonism consisting of akinesia, resting tremor, rigidity, and postural instability. Neuropathological examination revealed a marked loss of nigral neurons, but no Lewy bodies (LBs) were observed. Lewy bodies were also absent from their usual site...

journal_title：Journal of the neurological sciences

authors： Ishihara K,Nonaka A,Fukui T,Kawamura M,Shiota J,Nakano I

更新日期：2002-06-15 00:00:00

abstract：:Iodized oil was administered as a single intramuscular injection to pregnant iodine-deficient ewes at 100 days gestation and the subsequent growth of their fetuses compared with that of fetuses of severely iodine-deficient ewes and of iodine-replete ewes, all of which were fed the same low-iodine diet. The administere...

journal_title：Journal of the neurological sciences

authors： Potter BJ,Mano MT,Belling GB,Martin DM,Cragg BG,Chavadej J,Hetzel BS

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND:Both intra-arterial recombinant tissue plasminogen activator (rt-PA) and stent retrieval are effective for treating acute ischemic stroke. The goal of this study was to evaluate the effectiveness of stent retrieval combined with intra-arterial rt-PA administration via micro-catheter (called the complex techn...

journal_title：Journal of the neurological sciences

authors： Yi TY,Chen WH,Wu YM,Zhang MF,Lin DL,Lin XH

更新日期：2018-03-15 00:00:00

abstract：:Hemichorea associated with carotid artery occlusive disease is extremely rare. It has been recently suggested that carotid artery stenosis should be considered in the differential diagnosis of chorea, even in the absence of a preceding stroke or transient ischemic attack. Although the pathophysiology of this condition...

journal_title：Journal of the neurological sciences

authors： Pareés I,Pujadas F,Hernández-Vara J,Lorenzo-Bosquet C,Cuberas G,Munuera J,Alvarez-Sabín J

更新日期：2011-01-15 00:00:00

abstract：:Cortical tissue oxygen measured by a platinum cathode, and cerebral blood flow recorded by a hydrogen clearance technique, were measured in 13 baboons before, during and after temporary occlusion of the middle cerebral artery. Mean control pO2 was 23.8 +/- 14 mm Hg and mean flow 51.3 +/- 12 ml/100g/min. During the occ...

journal_title：Journal of the neurological sciences

authors： Crockard HA,Symon L,Branston NM,Juhasz J

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:VTI1A and ETFA were identified recently as susceptibility genes for non-glioblastoma (GBM) of glioma risk in European populations, but the genetic etiology and pathogenesis of glioma have not been fully elucidated. Here, we aimed to investigate whether common genetic variants in VTI1A and ETFA predispose Han...

journal_title：Journal of the neurological sciences

authors： Wang N,Deng Z,Wang M,Li R,Xu G,Bao G

更新日期：2017-04-15 00:00:00

abstract：:The occurrence of clusters of Marchi-positive granules and of Marchi-positive myelinoid bodies at different postnatal developmental stages was examined lightmicroscopically in Vibratome sections from the cervical lateral funiculus of the cat, after perfusion-fixation with glutaraldehyde. The findings show that cluster...

journal_title：Journal of the neurological sciences

authors： Remahl S,Risling M,Hildebrand C

更新日期：1977-10-01 00:00:00

abstract：:Neuropsychological impairment is a common manifestation in multiple sclerosis (MS) and is found in 40-60% of patients. The pattern of cognitive impairment in MS is characterized by difficulties in recent memory, sustained attention, executive functions and information processing speed. These cognitive deficits have a ...

journal_title：Journal of the neurological sciences

authors： Porcel J,Montalban X

更新日期：2006-06-15 00:00:00

abstract：:It has been suggested that amyotrophic lateral sclerosis (ALS), a neurodegenerative disorder resulting in motor neuron death, is associated with oxidative damage induced by free radicals. Our study aimed to get an assessment of the blood oxidative stress status in a population of 167 ALS patients (aged 59+/-13 years),...

journal_title：Journal of the neurological sciences

authors： Bonnefont-Rousselot D,Lacomblez L,Jaudon M,Lepage S,Salachas F,Bensimon G,Bizard C,Doppler V,Delattre J,Meininger V

更新日期：2000-09-01 00:00:00

abstract：:We report two patients with numb clumsy hands due to cervical spondylotic spinal cord compression. It is proposed that arterial insufficiency in the watershed area between the central and radial arterial systems of the cervical cord explains the sensory findings in the upper extremities with preservation of motor func...

journal_title：Journal of the neurological sciences

authors： Romano JG,Bradley WG,Green B

更新日期：1996-09-01 00:00:00

abstract：:Relative contributions of two potential pathogenetic factors for cognitive impairments among patients with multi-infarct dementia (MID) are reported. Cognitive test scores were correlated with measures of cerebral hypoperfusion and loss of brain parenchyma. Local cerebral blood flow values were determined utilizing st...

journal_title：Journal of the neurological sciences

authors： Kawamura J,Meyer JS,Terayama Y,Weathers S

更新日期：1991-03-01 00:00:00

abstract：:Benign familial neonatal convulsions (BFNC) are a rare autosomal dominant inherited epilepsy syndrome. Two voltage-gated potassium channel genes, KCNQ2 on chromosome 20q13.3 and KCNQ3 on chromosome 8q24, have been identified as the genes responsible for benign familial neonatal convulsions. By linkage analysis and mut...

journal_title：Journal of the neurological sciences

authors： Tang B,Li H,Xia K,Jiang H,Pan Q,Shen L,Long Z,Zhao G,Cai F

更新日期：2004-06-15 00:00:00

abstract：:With an Italian case series of 81 Italian patients and 130 controls, we analysed associations between myasthenia gravis (MG) and genetic polymorphisms in the MHC class II/III region. Increases in the frequency of the TNF-B*1, C4A*Q0, C4B*1, DRB1*03 supratype, which is likely part of the 8.1 ancestral haplotype, were m...

journal_title：Journal of the neurological sciences

authors： Franciotta D,Cuccia M,Dondi E,Piccolo G,Cosi V

更新日期：2001-09-15 00:00:00

abstract：BACKGROUND:Fatigue is a common and debilitating symptom in multiple sclerosis (MS). Over the past decade, a growing body of research has focussed on the pathophysiological mechanisms underlying central (cognitive and physical) fatigue in MS. The precise mechanisms causing fatigue in MS patients are complex and poorly u...

journal_title：Journal of the neurological sciences

authors： Arm J,Ribbons K,Lechner-Scott J,Ramadan S

更新日期：2019-05-15 00:00:00

abstract：:Fingolimod is the first oral disease-modifying therapy approved for relapsing forms of multiple sclerosis (MS). Following phosphorylation in vivo, the active agent, fingolimod phosphate (fingolimod-P), acts as a sphingosine 1-phosphate (S1P) receptor modulator, binding with high affinity to four of the five known S1P ...

journal_title：Journal of the neurological sciences

authors： Groves A,Kihara Y,Chun J

更新日期：2013-05-15 00:00:00

abstract：:This study included 40 consecutive patients with athrothrombotic carotid occlusive disease (A-group) and 13 consecutive patients with moyamoya disease (M-group) who had an internal carotid artery occlusion and underwent EC-IC bypass. Flow velocity and diameter of the operated STA on duplex ultrasonography (STDU), as w...

journal_title：Journal of the neurological sciences

authors： Fujimoto S,Toyoda K,Inoue T,Jinnouchi J,Kitazono T,Okada Y

更新日期：2013-02-15 00:00:00

abstract：:The purpose of the investigation was to elucidate the repeatedly discussed relationship between chronic lead intoxication and ALS. The following mean lead concentrations were determined in 9 patients with ALS: 8.65 +/- 3,91 micrograms/100 ml in the blood, 0.97 +/- 0.78 microgram/100 ml in the plasma, 19.15 +/- 5.0 mic...

journal_title：Journal of the neurological sciences

authors： Stober T,Stelte W,Kunze K

更新日期：1983-09-01 00:00:00

abstract：:In the last two decades functional magnetic resonance imaging (fMRI) has dominated research in neuroscience. However, only recently has it taken the first steps in translation to the clinical field. In this paper we describe the advantages of fMRI and DTI and the possible benefits of implementing these methods in clin...

journal_title：Journal of the neurological sciences

authors： Bick AS,Mayer A,Levin N

更新日期：2012-01-15 00:00:00

abstract：BACKGROUND:Although predominantly reported in patients with status epilepticus, periictal MRI abnormalities have been reported in patients with a single or a cluster of seizures. Clinicians are often presented with a dilemma concerning the features of MRI abnormalities induced by a single or a cluster of seizures, as t...

journal_title：Journal of the neurological sciences

authors： Xiang T,Li G,Liang Y,Zhou J

更新日期：2014-08-15 00:00:00

abstract：:Peripheral nerve injury results in a series of events culminating in degradation of the axonal cytoskeleton (Wallerian degeneration). In the time period between axotomy and cytoskeletal degradation (24-48 h in rodents), there is calcium entry and activation of calpains within the axon. The precise timing of these even...

journal_title：Journal of the neurological sciences

authors： Glass JD,Culver DG,Levey AI,Nash NR

更新日期：2002-04-15 00:00:00

abstract：:DNA amplification of three Mycobacterium tuberculosis-specific DNA sequences by the polymerase chain reaction (PCR) were evaluated as a means for rapid diagnosis of tuberculous meningitis (TBM). The DNA sequences amplified were a 123 bp region of the IS6110 insertion elements which occur in multiple copies in the myco...

journal_title：Journal of the neurological sciences

authors： Lee BW,Tan JA,Wong SC,Tan CB,Yap HK,Low PS,Chia JN,Tay JS

更新日期：1994-05-01 00:00:00