Bilateral claw hand: an uncommon presentation of regional Guillain-Barré syndrome.


:We present an uncommon case of a 38-year-old man presented with bilateral subacute weakness of intrinsic hand muscles, manifesting as bilateral claw-hand, without sensory deficits and absent tendon reflexes in upper arms. Nerve conduction studies showed findings consistent with demyelinating GBS. During the fourth day of hospitalization the patient presented symmetrical distal leg weakness and was treated with intravenous immunoglobulin.


J Neurol Sci


Tsivgoulis G,Tsakaldimi S,Vadikolias K,Mantatzis M,Katsanos AH,Heliopoulos I,Piperidou C




Has Abstract


2013-11-15 00:00:00














  • Immunofluorescence study of lymphocytic infiltration in gliomas. Identification of T-lymphocytes.

    abstract::Five human brain tumours (3 glioblastomas and 2 astrocytomas) and 5 rat brain tumours induced in Sprague--Dawley animals by systemic administration of N-methyl-N-nitrosourea (3 pleomorphic gliomas and 2 mixed gliomas) were studied. The human brain tumours were surgical specimens excised from patients with no cranial s...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Stavrou D,Anzil AP,Weidenbach W,Rodt H

    更新日期:1977-08-01 00:00:00

  • A comparison of community-residing older adults with frontal and parkinsonian gaits.

    abstract::Frontal gaits (FG) and parkinsonian gaits (PG) are common neurological gait abnormalities in older adults. It may be difficult to distinguish these gaits as they share common clinical characteristics such as unsteadiness, slowing, and shuffling. Of 488 community-residing subjects in an aging study, 11 were diagnosed w...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Ambrose A,Levalley A,Verghese J

    更新日期:2006-10-25 00:00:00

  • Factors influencing a patient's decision regarding riluzole: an early experience.

    abstract::Riluzole is the first drug to be approved in the United States for the treatment of amyotrophic lateral sclerosis (ALS). During the first 8 months of the drug's availability by prescription, its use was discussed with 46 patients with probable or definite ALS as defined by the E1 Escorial criteria. Seventeen of the pa...

    journal_title:Journal of the neurological sciences

    pub_type: 临床试验,杂志文章


    authors: Rudnicki SA

    更新日期:1997-10-01 00:00:00

  • Interleukin-1 and interleukin-2 production by peripheral blood mononuclear cells in multiple sclerosis patients.

    abstract::The production of interleukin-1 (IL-1) and interleukin-2 (IL-2) by peripheral blood mononuclear cells (PBM) was assessed in multiple sclerosis (MS) patients in relapse, chronic progressive MS patients, patients with other neurological diseases (OND) and healthy subjects. Production was defined as the level of IL-1 and...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Selmaj K,Nowak Z,Tchórzewski H

    更新日期:1988-05-01 00:00:00

  • Neuropeptides in Alzheimer's disease, depression and schizophrenia. A post mortem analysis of vasoactive intestinal peptide and cholecystokinin in cerebral cortex.

    abstract::Vasoactive intestinal peptide (VIP) and cholecystokinin (CCK) have been measured, by radioimmunoassay, in cerebral cortex obtained at autopsy from patients without neurological or psychiatric disease and from patients with Alzheimer's disease, depression and schizophrenia. Sephadex gel filtration indicated that over 9...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Perry RH,Dockray GJ,Dimaline R,Perry EK,Blessed G,Tomlinson BE

    更新日期:1981-09-01 00:00:00

  • Hypermetabolism is a reality in amyotrophic lateral sclerosis compared to healthy subjects.

    abstract:RATIONALE:Hypermetabolism (HM) in Amyotrophic lateral sclerosis (ALS) is the reflection of a high energy metabolic level, but this alteration seems controversial. The main objective of the study was to confirm the existence of HM during ALS compared to healthy subjects. METHODS:A cohort of ALS patients was compared to...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Fayemendy P,Marin B,Labrunie A,Boirie Y,Walrand S,Achamrah N,Coëffier M,Preux PM,Lautrette G,Desport JC,Couratier P,Jésus P

    更新日期:2021-01-15 00:00:00

  • Usefulness of combining 123I-FP-CIT-SPECT striatal asymmetry index and cardiac 123I-metaiodobenzylguanidine scintigraphy examinations for diagnosis of parkinsonisms.

    abstract:BACKGROUND:Although single-photon emission computerized tomography of the dopamine transporter (DAT-SPECT) is useful for diagnosing parkinsonian syndrome, its applicability toward the early phase of Parkinson's disease remains unknown. METHODS:We enrolled 32 patients showing parkinsonism with normal cardiac 123I-metai...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Niimi Y,Ito S,Murate K,Hirota S,Hikichi C,Ishikawa T,Maeda T,Nagao R,Shima S,Mizutani Y,Ueda A,Mutoh T

    更新日期:2017-06-15 00:00:00

  • Hypnic headache: A review of 348 cases published from 1988 to 2018.

    abstract::Hypnic headache (HH) is a rare benign disorder described initially by Raskin in 1988. It is characterized by recurrent nocturnal episodes of headache that periodically awaken the sleeping patient and usually occur in the elderly. This review aimed to describe the clinical features of the HH cases published in the lite...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章,评审


    authors: Silva-Néto RP,Santos PEMS,Peres MFP

    更新日期:2019-06-15 00:00:00

  • Acetylcholine receptors in cultured human muscle cells.

    abstract::Primary cultures prepared from human muscle biopsies were examined for the presence and distribution of acetylcholine receptors, as measured by the binding of 125iodine-labelled alpha-bungarotoxin. The toxin bound to the human muscle cultures with a similar time dependence and specificity as found in muscle cultures f...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Franklin GI,Yasin R,Hughes BP,Thompson EJ

    更新日期:1980-09-01 00:00:00

  • Accuracy of CSF and MRI criteria for dissemination in space in the diagnosis of multiple sclerosis.

    abstract::Demonstration of lesion dissemination in space (DIS) and time (DIT) is necessary for the diagnosis of multiple sclerosis (MS) in clinically isolated syndromes (CIS). The McDonald criteria accepted two methods to demonstrate DIS. The fulfillment of at least three of four MRI Barkhof criteria (MRI-BC) or, alternatively,...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Villar LM,García-Barragán N,Sádaba MC,Espiño M,Gómez-Rial J,Martínez-San Millán J,González-Porqué P,Alvarez-Cermeño JC

    更新日期:2008-03-15 00:00:00

  • Altered intrinsic brain activity in patients with familial cortical myoclonic tremor and epilepsy: an amplitude of low-frequency fluctuation study.

    abstract:PURPOSE:To investigate localized cerebral function abnormalities in patients with familial cortical myoclonic tremor and epilepsy (FCMTE) using resting-state functional magnetic resonance imaging (fMRI). METHODS:Seven patients with FCMTE from a Chinese family, seven patients with essential tremor (ET), and ten healthy...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Wang P,Luo C,Dong L,Bin Y,Ma S,Yao D,Guo F,Yang Z

    更新日期:2015-04-15 00:00:00

  • Impact of aerobic training on immune-endocrine parameters, neurotrophic factors, quality of life and coordinative function in multiple sclerosis.

    abstract::In recent years it has become clear that multiple sclerosis (MS) patients benefit from physical exercise as performed in aerobic training but little is known about the effect on functional domains and physiological factors mediating these effects. We studied immunological, endocrine and neurotrophic factors as well as...

    journal_title:Journal of the neurological sciences

    pub_type: 临床试验,杂志文章


    authors: Schulz KH,Gold SM,Witte J,Bartsch K,Lang UE,Hellweg R,Reer R,Braumann KM,Heesen C

    更新日期:2004-10-15 00:00:00

  • The C57BL mice: an animal model for inflammatory demyelinating polyneuropathy.

    abstract::Recently it has been reported that the C57BL mice can be used as a model of benign monoclonal gammopathy (MG). Since experimental models have until now failed to reproduce specific lesions of human dysglobulinemic polyneuropathies, we decided to investigate the peripheral nerve of these mice. The sciatic nerve and the...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Dib M,Vital A,Vital C,Georgescault D,Baquey A,Bezian J

    更新日期:1987-10-01 00:00:00

  • Anti-beta 2-glycoprotein I antibodies bind to central nervous system.

    abstract::Anti-beta 2-GPI antibodies (a beta 2-GPI) were found in serum from patients with anti-phospholipid syndrome (APS) and/or systemic lupus erythematosus (SLE). Since a beta 2-GPI are often found in patients with anti-cardiolipin antibodies (aCL), their role in thrombosis as well as other central nervous system (CNS) mani...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Caronti B,Pittoni V,Palladini G,Valesini G

    更新日期:1998-04-01 00:00:00

  • The clinical value of therapeutic plasma exchange in multifocal motor neuropathy.

    abstract:OBJECTIVE:Although there is evidence for a pathogenic role of humoral factors in multifocal motor neuropathy (MMN), plasma exchange (PE) is assumed to be an ineffective treatment. We set out to elucidate possible reasons for this apparent contradiction. METHODS:A retrospective analysis of seven patients with MMN, who ...

    journal_title:Journal of the neurological sciences

    pub_type: 临床试验,杂志文章


    authors: Lehmann HC,Hoffmann FR,Fusshoeller A,Meyer zu Hörste G,Hetzel R,Hartung HP,Schroeter M,Kieseier BC

    更新日期:2008-08-15 00:00:00

  • Safety of nitrous oxide administration in patients with Charcot-Marie-Tooth disease.

    abstract::Nitrous oxide is routinely administered to children and adults with Charcot-Marie-Tooth disease (CMT) as an anaesthetic for procedures such as nerve conduction studies and maintenance for general anaesthesia. However it is listed as a 'moderate to significant' risk of potential toxicity and worsening neuropathy in peo...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章,评审


    authors: Isbister GK,Burns J,Prior F,Ouvrier RA

    更新日期:2008-05-15 00:00:00

  • White matter changes mimicking a leukodystrophy in a patient with Mucopolysaccharidosis: characterization by MRI.

    abstract::Mucopolysaccharidosis (MPS) type I (alpha-iduronidase deficiency) is characterized by storage and massive urinary excretion of dermatan sulfate and heparan sulfate; it may be distinguished into three different subtypes based on age at onset and severity of the clinical symptoms. We report on progressive white matter i...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Barone R,Parano E,Trifiletti RR,Fiumara A,Pavone P

    更新日期:2002-03-30 00:00:00

  • Neuromyotonia: autoimmune pathogenesis and response to immune modulating therapy.

    abstract:BACKGROUND:Neuromyotonia (NMT) has been postulated to be an autoimmune channelopathy, probably by affecting voltage gated potassium channels (VGKC) leading to excitation and abnormal discharges [Sinha et al., Lancet 338 (1991) 75]. OBJECTIVE:To report three patients with NMT who had other associated immune-mediated co...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Hayat GR,Kulkantrakorn K,Campbell WW,Giuliani MJ

    更新日期:2000-12-01 00:00:00

  • Association of phosphorylation site of tau protein with neuronal apoptosis in Alzheimer's disease.

    abstract::In addition to neuritic changes and amyloid deposits, neuronal and glial cell apoptosis is an important pathological feature of Alzheimer's disease (AD). Several factors have been postulated as causes or triggers of cellular apoptotic change. This study focused on a quantifiable relationship between phosphorylation si...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Kobayashi K,Nakano H,Hayashi M,Shimazaki M,Fukutani Y,Sasaki K,Sugimori K,Koshino Y

    更新日期:2003-04-15 00:00:00

  • Anosmia is associated with lower in-hospital mortality in COVID-19.

    abstract:BACKGROUND:Anosmia is common in Coronavirus disease 2019, but its impact on prognosis is unknown. We analysed whether anosmia predicts in-hospital mortality; and if patients with anosmia have a different clinical presentation, inflammatory response, or disease severity. METHODS:Retrospective cohort study including all...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Talavera B,García-Azorín D,Martínez-Pías E,Trigo J,Hernández-Pérez I,Valle-Peñacoba G,Simón-Campo P,de Lera M,Chavarría-Miranda A,López-Sanz C,Gutiérrez-Sánchez M,Martínez-Velasco E,Pedraza M,Sierra Á,Gómez-Vicente B,Guerre

    更新日期:2020-12-15 00:00:00

  • Differentiation of Parkinson's disease and multiple system atrophy in early disease stages by means of I-123-MIBG-SPECT.

    abstract:BACKGROUND:Differential diagnosis between idiopathic Parkinson's disease (PD) and multiple system atrophy (MSA) is often difficult in early disease stages. Since MSA is misdiagnosed as PD in more than 20% of the early stages, there is need for methods refining the differentiation of the two disease entities. In PD post...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Druschky A,Hilz MJ,Platsch G,Radespiel-Tröger M,Druschky K,Kuwert T,Neundörfer B

    更新日期:2000-04-01 00:00:00

  • Evaluating the association of allergies with multiple sclerosis susceptibility risk and disease activity in a pediatric population.

    abstract:BACKGROUND:Multiple sclerosis (MS) and allergies are both considered to be related to imbalanced Th1 and Th2 immune responses. Previous studies evaluating the relationship between MS and allergies provide conflicting results. OBJECTIVE:To assess allergies and asthma as risk factors for MS and as predictors of MS relap...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章,多中心研究


    authors: Bourne T,Waltz M,Casper TC,Kavak K,Aaen G,Belman A,Benson L,Candee M,Chitnis T,Graves J,Greenberg B,Gorman M,Harris Y,Krupp L,Lotze T,Mar S,Ness J,Olsen C,Roalstad S,Rodriguez M,Rose J,Rubin J,Schreiner T,Ti

    更新日期:2017-04-15 00:00:00

  • Using diffusion-weighted MRI in multicenter clinical trials for multiple sclerosis.

    abstract::This paper reviews the current state of knowledge about the use of diffusion-weighted MRI in the field of multiple sclerosis (MS) research. The contribution that diffusion-weighted imaging has made to our understanding of MS is critically appraised, and pointers are given to the sort of work that needs to be done befo...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章,评审


    authors: Horsfield MA

    更新日期:2001-05-01 00:00:00

  • Involvement of hippocampus in Creutzfeldt-Jakob disease.

    abstract::The hippocampus is generally believed to be only rarely affected in Creutzfeldt-Jakob disease. In a systematic study of the hippocampus in 6 cases of Creutzfeldt-Jakob disease, the stratum moleculare-lacunosum showed a definite spongiform change with gliosis in 5 cases. The stratum radiatum et pyramidale showed spongi...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Mizusawa H,Hirano A,Llena JF

    更新日期:1987-12-01 00:00:00

  • Differentiating progressive supranuclear palsy from Parkinson's disease by MRI-based dynamic cerebrospinal fluid flow.

    abstract:OBJECTIVE:The purpose of this study was to clarify the difference between PSP and PD from the viewpoint of dynamic cerebrospinal fluid (CSF) flow focusing on the midbrain aqueduct. METHODS:Thirty-three PD patients (mean age 69.2±7.9) and 35 PSP patients (mean age 70.5±6.6) were included in this study. CSF flow was cal...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Fukui Y,Hishikawa N,Sato K,Yunoki T,Kono S,Matsuzono K,Nakano Y,Ohta Y,Yamashita T,Deguchi K,Abe K

    更新日期:2015-10-15 00:00:00

  • Mouse nerve growth factor promotes neurological recovery in patients with acute intracerebral hemorrhage: A proof-of-concept study.

    abstract:BACKGROUND:ew drugs were confirmed to be effective in the treatments of neurological dysfunction caused by acute intracerebral hemorrhage (ICH). The present prospective clinical trial aims to evaluate the effect of mouse nerve growth factor (mNGF) on neurological function in patients with acute ICH. METHODS:60 patient...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: An S,Jia Y,Tian Y,Sun J,Wei Y,Yue S,Lin L,Wei Y,Li Y,Lei P,Zhang J,Jiang R

    更新日期:2020-11-15 00:00:00

  • Case-control study of risk of Parkinson's disease in relation to hypertension, hypercholesterolemia, and diabetes in Japan.

    abstract::This case-control study investigated the associations of a history of hypertension, hypercholesterolemia, and diabetes mellitus with the risk of Parkinson's disease (PD) in Japan. Included were 249 cases within 6 years of onset of PD. Controls were 368 inpatients and outpatients without a neurodegenerative disease. Da...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章,多中心研究


    authors: Miyake Y,Tanaka K,Fukushima W,Sasaki S,Kiyohara C,Tsuboi Y,Yamada T,Oeda T,Miki T,Kawamura N,Sakae N,Fukuyama H,Hirota Y,Nagai M,Fukuoka Kinki Parkinson's Disease Study Group.

    更新日期:2010-06-15 00:00:00

  • Quantitative analysis of brainstem atrophy on magnetic resonance imaging in chronic progressive neuro-Behçet's disease.

    abstract:OBJECTIVES:To examine whether quantitative analysis of the brainstem areas on magnetic resonance imaging (MRI) scans is useful for diagnosis as well as evaluation of disease activity in chronic progressive neuro-Behçet's disease (CPNB). METHODS:MRI scans in patients with acute neuro-Behçet's disease (ANB) (n = 10), CP...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Kikuchi H,Takayama M,Hirohata S

    更新日期:2014-02-15 00:00:00

  • Stent-unsheathed effect predicts acute distal middle cerebral artery atherosclerotic disease-related occlusion.

    abstract:BACKGROUND:The differentiation of intracranial atherosclerosis (ICAS) and embolism is important. OBJECTIVE:In cases of ICAS, we observe a phenomenon that we call the "post-stent-deployment effect"; that is, all major branches are clearly visible beyond the occlusion segment when the stent is deployed at the site of oc...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Chen WH,Yi TY,Zhan AL,Wu YM,Lu YY,Li YM,Pan ZN,Lin DL,Lin XH

    更新日期:2020-09-15 00:00:00

  • Detection and management of cardiomyopathy in female dystrophinopathy carriers.

    abstract::Regular health checkups for mothers of patients with Duchenne muscular dystrophy have been performed at National Hospital Organization Tokushima Hospital since 1994. Among 43 mothers participated in this study, 28 dystrophinopathy carriers were identified. Skeletal and cardiac muscle functions of these subjects were e...

    journal_title:Journal of the neurological sciences

    pub_type: 杂志文章


    authors: Adachi K,Hashiguchi S,Saito M,Kashiwagi S,Miyazaki T,Kawai H,Yamada H,Iwase T,Akaike M,Takao S,Kobayashi M,Ishizaki M,Matsumura T,Mori-Yoshimura M,Kimura E

    更新日期:2018-03-15 00:00:00