Abstract:
:Two hundred five patients with Kawasaki disease and 500 normal controls were HLA-typed, using a standard microcytotoxicity test of tissue typing. HLA-BW22 was more common in patients with Kawasaki disease than in normal controls (25.4% instead of 11.8%, corrected P less than .0005). Among subtypes of HLA-BW22 antigen, Kawasaki disease was associated with HLA-BW22J2, which was found specifically in Japanese and not in Caucasians. These facts may suggest that there is a gene controlling the susceptibility to Kawasaki disease and linked with a Japanese-specific HLA antigen.
journal_name
Pediatricsjournal_title
Pediatricsauthors
Kato S,Kimura M,Tsuji K,Kusakawa S,Asai T,Juji T,Kawasaki Tsubject
Has Abstractpub_date
1978-02-01 00:00:00pages
252-5issue
2eissn
0031-4005issn
1098-4275journal_volume
61pub_type
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