Abstract：
BACKGROUND:The validity of self-reported varicella history and cost-effectiveness of a prevaccination screening strategy have not been examined among health care workers (HCWs) living in Korea. METHODS:We investigated varicella-zoster virus immunity of all HCWs in high-risk departments. To determine the history of varicella, all applicants completed a standardized questionnaire at the time of blood sampling for serologic testing. RESULTS:Of the 550 HCWs, 526 (96%) were varicella seropositive. Although self-reported history was highly predictive of seropositivity (≥96%) among all age groups, the negative predictive value was extremely low (4%-5%) among all age groups. The prevaccination screening strategy was cheaper than vaccination without antibody screening if the varicella seroprevalence was >28%. CONCLUSION:Seroprevalence was high (≥95%) among HCWs born in Korea before 1988. The self-reported varicella history did not accurately predict immunity, especially for individuals who have negative or uncertain varicella history. Given the high seroprevalence of varicella in Korean HCWs, serologic screening before vaccination was more cost-effective than universal vaccination.
journal_name
Am J Infect Controljournal_title
American journal of infection controlauthors
Kang JH,Park YS,Park SY,Kim SB,Ko KP,Seo YHdoi
10.1016/j.ajic.2014.05.013subject
Has Abstractpub_date
2014-08-01 00:00:00pages
885-7issue
8eissn
0196-6553issn
1527-3296pii
S0196-6553(14)00806-2journal_volume
42pub_type
杂志文章abstract：:The Association for Professionals in Infection Control and Epidemiology (APIC) began publishing their series of Elimination Guides in 2007. Since then, 9 Elimination Guides have been developed that cover a range of important infection prevention issues, including the prevention of catheter-related bloodstream infectio...
journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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doi：10.1016/j.ajic.2006.05.288
更新日期：2006-12-01 00:00:00
abstract：:In 1982 the Centers for Disease Control published a set of recommendations and measures to protect persons working in health care settings or performing mortician services from possible exposure to the human immunodeficiency virus. This study of a number of funeral homes in the Fort Worth area was designed to determin...
journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/0196-6553(89)90130-2
更新日期：1989-08-01 00:00:00
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journal_title：American journal of infection control
pub_type： 杂志文章,评审
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更新日期：1999-10-01 00:00:00
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pub_type： 杂志文章,meta分析
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abstract：BACKGROUND:Biocidal high-touch surfaces contact surfaces can be used to help reduce healthcare-acquired infections (HAIs). While the bactericidal protocols are well developed, there remains high variability in the methods used to evaluate the virucidal properties of such surfaces. This paper seeks to identify the most ...
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journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2009.11.003
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