Ventilation requirements during high frequency ventilation.

abstract：OBJECTIVE:To determine the incidence and risk factors of chronic critical illness after severe blunt trauma. DESIGN:Prospective observational cohort study (NCT01810328). SETTING:Two level-one trauma centers in the United States. PATIENTS:One hundred thirty-five adult blunt trauma patients with hemorrhagic shock who ...

journal_title：Critical care medicine

authors： Mira JC,Cuschieri J,Ozrazgat-Baslanti T,Wang Z,Ghita GL,Loftus TJ,Stortz JA,Raymond SL,Lanz JD,Hennessy LV,Brumback B,Efron PA,Baker HV,Moore FA,Maier RV,Moldawer LL,Brakenridge SC

更新日期：2017-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the effectiveness of lorazepam and midazolam for long-term sedation of critically ill, mechanically ventilated patients. DESIGN:Double-blind, randomized, controlled study. SETTING:Medical intensive care unit in a university teaching hospital. PATIENTS:Sixty-four evaluable adult patients admitte...

journal_title：Critical care medicine

authors： Swart EL,van Schijndel RJ,van Loenen AC,Thijs LG

更新日期：1999-08-01 00:00:00

abstract：:A polarographic conjunctival oxygen sensor was used to measure oxygen tension in a tissue bed supplied by the internal carotid artery. The shared vascular source of the conjunctiva and brain suggests that conjunctival PO2 monitoring may provide an index of cerebral perfusion. We studied the effects of hyperventilation...

journal_title：Critical care medicine

authors： Nisam M,Albertson TE,Panacek E,Rutherford W,Fisher CJ Jr

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the hypothesis that splanchnic ischemia and mucosal hypoxia are responsible for lipopolysaccharide-induced intramucosal acidosis in pigs. DESIGN:Prospective, randomized, unblinded study. SETTING:Surgical research laboratory at a large, university-affiliated medical center. SUBJECTS:Anesthetized...

journal_title：Critical care medicine

authors： VanderMeer TJ,Wang H,Fink MP

更新日期：1995-07-01 00:00:00

abstract：:Arterial and transcutaneous O2 (PtcO2) and CO2 (PtcCO2) tensions, arterial O2 saturations (SaO2) and P50 values were measured in 47 patients before extubation. In order to unmask ventilation to perfusion (VA/Q) inequality, all variables were obtained without CPAP and with FIO2 of 0.40 as well as with CPAP of 5 cm H2O ...

journal_title：Critical care medicine

authors： Tahvanainen J,Nikki P

更新日期：1983-09-01 00:00:00

abstract：OBJECTIVES:To assess the impact of the percentage of fluid infused as Lactated Ringer (%LR) during the first 2 days of ICU admission in hospital mortality and occurrence of acute kidney injury. DESIGN:Retrospective cohort. SETTING:Analysis of a large public database (Multiparameter Intelligent Monitoring in Intensive...

journal_title：Critical care medicine

authors： Zampieri FG,Ranzani OT,Azevedo LC,Martins ID,Kellum JA,Libório AB

更新日期：2016-12-01 00:00:00

abstract：:The hospital records of 7 patients with severe bronchopulmonary dysplasia (BPD) were reviewed. All patients were ventilator dependent for prolonged periods (mean duration intermittent mandatory ventilation (IMV) 14.3 +/- 3.5 months) but eventually were successfully weaned from mechanical ventilation and sent home. The...

journal_title：Critical care medicine

authors： Morray JP,Fox WW,Kettrick RG,Downes JJ

更新日期：1981-12-01 00:00:00

abstract：OBJECTIVES:To investigate the effects of recombinant human erythropoietin on brain oxygenation in a model of diffuse traumatic brain injury. DESIGN:Adult male Wistar rats. SETTING:Neurosciences and physiology laboratories. INTERVENTIONS:Thirty minutes after diffuse traumatic brain injury (impact-acceleration model),...

journal_title：Critical care medicine

authors： Bouzat P,Millet A,Boue Y,Pernet-Gallay K,Trouve-Buisson T,Gaide-Chevronnay L,Barbier EL,Payen JF

更新日期：2013-05-01 00:00:00

abstract：OBJECTIVE:Initial success with chimeric antigen receptor-modified T cell therapy for relapsed/refractory acute lymphoblastic leukemia is leading to expanded use through multicenter trials. Cytokine release syndrome, the most severe toxicity, presents a novel critical illness syndrome with limited data regarding diagnos...

journal_title：Critical care medicine

authors： Fitzgerald JC,Weiss SL,Maude SL,Barrett DM,Lacey SF,Melenhorst JJ,Shaw P,Berg RA,June CH,Porter DL,Frey NV,Grupp SA,Teachey DT

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:Antibiotic therapy is a major risk factor for the development of diarrhea and colitis with varying severity. Often the origin of antibiotic-associated gastrointestinal deterioration remains elusive and no specific infectious agents could be discerned. PATIENTS:We represent three cases of intractable high-vol...

journal_title：Critical care medicine

authors： Wurm P,Spindelboeck W,Krause R,Plank J,Fuchs G,Bashir M,Petritsch W,Halwachs B,Langner C,Högenauer C,Gorkiewicz G

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVES:To assess the variability in short-term sepsis mortality by hospital among Centers for Medicare and Medicaid Services beneficiaries in the United States during 2013-2014. DESIGN:A retrospective cohort design. SETTING:Hospitalizations from 3,068 acute care hospitals that participated in the Centers for Medi...

journal_title：Critical care medicine

authors： Hatfield KM,Dantes RB,Baggs J,Sapiano MRP,Fiore AE,Jernigan JA,Epstein L

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Remarkable progress has been made during the last decade in defining the molecular mechanisms that underlie septic shock. This rapidly expanding field is leading to new therapeutic opportunities in the management of severe sepsis. AIM:To provide the clinician with a timely summary of the molecular biology o...

journal_title：Critical care medicine

authors： Cinel I,Opal SM

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:Our intent was to evolve a prognosticator that would predict the likelihood that an electrical shock would restore a perfusing rhythm. Such a prognosticator was to be based on conventional electrocardiographic signals but without constraints caused by artifacts resulting from precordial compression. The adver...

journal_title：Critical care medicine

authors： Marn-Pernat A,Weil MH,Tang W,Pernat A,Bisera J

更新日期：2001-12-01 00:00:00

abstract：OBJECTIVE:To determine the long-term outcome of noninvasive ventilation in chronic obstructive pulmonary disease patients who refused intubation for acute hypercapnic respiratory failure. DESIGN:Prospective, observational study. SETTING:Noninvasive ventilation unit in an acute regional hospital in Hong Kong. METHODS...

journal_title：Critical care medicine

authors： Chu CM,Chan VL,Wong IW,Leung WS,Lin AW,Cheung KF

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:With limited community services, the complex rehabilitation period after critical illness is often the responsibility of family members who, as a result, may experience negative health outcomes. The objectives of this research were to a) identify aspects of the caregiving situation that are associated with ca...

journal_title：Critical care medicine

authors： Cameron JI,Herridge MS,Tansey CM,McAndrews MP,Cheung AM

更新日期：2006-01-01 00:00:00

abstract：BACKGROUND:The 2003 global outbreak of severe acute respiratory syndrome (SARS) provided numerous challenges to the delivery of critical care. The Toronto critical care community has learned important lessons from SARS, which will help in preparation for future disease outbreaks. OBJECTIVES:The objectives of this stud...

journal_title：Critical care medicine

authors： Booth CM,Stewart TE

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:Neutrophils are an important component of the inflammatory response that characterizes acute lung injury (ALI). This discussion aims to review the contribution of neutrophils to the development and progression of ALI and to highlight the major intracellular signaling pathways that are involved in neutrophil a...

journal_title：Critical care medicine

authors： Abraham E

更新日期：2003-04-01 00:00:00

abstract：OBJECTIVE:Despite concern over the appropriateness and quality of care provided in an intensive care unit (ICU) at the end of life, the number of Americans who receive ICU care at the end of life is unknown. We sought to describe the use of ICU care at the end of life in the United States using hospital discharge data ...

journal_title：Critical care medicine

authors： Angus DC,Barnato AE,Linde-Zwirble WT,Weissfeld LA,Watson RS,Rickert T,Rubenfeld GD,Robert Wood Johnson Foundation ICU End-Of-Life Peer Group.

更新日期：2004-03-01 00:00:00

abstract：:Because determining cardiac output is difficult in premature infants, little is known about the hemodynamic effects of PEEP in this age group. We used pulsed-wave Doppler echocardiography to assess the hemodynamic effects of PEEP increments in ten premature infants with respiratory distress syndrome. At a PEEP of 4 cm...

journal_title：Critical care medicine

authors： Hausdorf G,Hellwege HH

更新日期：1987-07-01 00:00:00

abstract：OBJECTIVE:Clinical trial designs that randomize patients to fixed treatment regimens may disrupt preexisting relationships between illness severity and level of therapy. The practice misalignments created by such designs may have unintended effects on trial results and safety. METHODS:To illustrate this problem, the T...

journal_title：Critical care medicine

authors： Deans KJ,Minneci PC,Suffredini AF,Danner RL,Hoffman WD,Ciu X,Klein HG,Schechter AN,Banks SM,Eichacker PQ,Natanson C

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:Circulating serum levels of procalcitonin rise significantly during bacterial infection. Because calcitonin is known to be a monocyte chemoattractant, we investigated whether procalcitonin, a prohormone of calcitonin, also affects leukocyte migration. DESIGN:Prospective, controlled in vitro study. SETTING:U...

journal_title：Critical care medicine

authors： Wiedermann FJ,Kaneider N,Egger P,Tiefenthaler W,Wiedermann CJ,Lindner KH,Schobersberger W

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:Transarterial chemoembolization is a widely used therapy for the treatment of hepatocellular carcinoma. A rare adverse event is acute respiratory distress syndrome from pulmonary embolization of Lipiodol, an iodinated oil commonly used during the procedure. The objective of this report is to describe an atypi...

journal_title：Critical care medicine

authors： Taupin D,Mukherjee V,Nathavitharana R,Green DA,Fridman D

更新日期：2014-06-01 00:00:00

abstract：OBJECTIVE:To compare the oxidative stress induced by IV iron infusion in critically ill patients and in healthy volunteers. DESIGN:Multicenter, interventional study. SETTING:Two ICUs and one clinical research center. SUBJECTS:Anemic critically ill patients treated with IV iron and healthy volunteers. INTERVENTIONS:...

journal_title：Critical care medicine

authors： Lasocki S,Piednoir P,Couffignal C,Rineau E,Dufour G,Lefebvre T,Puy H,Duval X,Driss F,Schilte C

更新日期：2016-03-01 00:00:00

abstract：OBJECTIVE:Because of their beneficial effects in patients with hemorrhagic shock and multiple-system trauma, hypertonic saline solutions are increasingly being used perioperatively for volume resuscitation. Although the anti-edema effects of hypertonic saline on brain are well documented in a variety of brain injury pa...

journal_title：Critical care medicine

authors： Toung TJ,Chen CH,Lin C,Bhardwaj A

更新日期：2007-02-01 00:00:00

abstract：OBJECTIVES:To determine the point prevalence of medication errors at the time of transition of care from an ICU to non-ICU location and assess error types and risk factors for medication errors during transition of care. DESIGN:This was a multicenter, retrospective, 7-day point prevalence study. SETTING:Fifty-eight I...

journal_title：Critical care medicine

authors： Tully AP,Hammond DA,Li C,Jarrell AS,Kruer RM

更新日期：2019-04-01 00:00:00

abstract：OBJECTIVE:Evaluations of plasma leptin and ghrelin levels and their relations with circulating levels of proinflammatory mediators, stress hormones, and biochemical markers of hepatorenal injury during experimental endotoxemia in dogs. SETTING:Uludag University. DESIGN:Placebo-controlled animal study. ANIMALS:Adult ...

journal_title：Critical care medicine

authors： Yilmaz Z,Ilcol YO,Ulus IH

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVES:To examine a hygroscopic condenser after clinical use and to describe the interaction of a hygroscopic condenser and a closed circuit suction system used simultaneously. DESIGN:Prospective evaluation of hygroscopic condensers used clinically, and laboratory investigation of a hygroscopic condenser used with...

journal_title：Critical care medicine

authors： Martinez FJ,Pietchel S,Wise C,Walek J,Beamis JF

更新日期：1994-10-01 00:00:00

abstract：OBJECTIVE:Sepsis is associated with a marked depression of cellular immune function. The steroid hormone dehydroepiandrosterone (DHEA) is proposed to have immunoenhancing activities. We, therefore, investigated the effect of DHEA on the mortality rate and cellular immune functions in an experimental model of sepsis. D...

journal_title：Critical care medicine

authors： Oberbeck R,Dahlweid M,Koch R,van Griensven M,Emmendörfer A,Tscherne H,Pape HC

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVES:To determine whether delirium during ICU stay is associated with long-term mental health problems defined as symptoms of anxiety, depression, and posttraumatic stress disorder. DESIGN:Prospective cohort study. SETTING:Survey study, 1 year after discharge from a medical-surgical ICU in the Netherlands. PAT...

journal_title：Critical care medicine

authors： Wolters AE,Peelen LM,Welling MC,Kok L,de Lange DW,Cremer OL,van Dijk D,Slooter AJ,Veldhuijzen DS

更新日期：2016-10-01 00:00:00

abstract：OBJECTIVE:Very elderly persons admitted to ICUs are at high risk of death. To document life-sustaining interventions (mechanical ventilation, vasopressors, renal replacement therapy) provided in the ICU and outcomes of care. DESIGN:Multicenter, prospective cohort study. SETTING:ICUs of 24 Canadian hospitals. PARTICI...

journal_title：Critical care medicine

authors： Heyland D,Cook D,Bagshaw SM,Garland A,Stelfox HT,Mehta S,Dodek P,Kutsogiannis J,Burns K,Muscedere J,Turgeon AF,Fowler R,Jiang X,Day AG,Canadian Critical Care Trials Group.,Canadian Researchers at the End of Life Network.

更新日期：2015-07-01 00:00:00