Migration of human monocytes in response to procalcitonin.

abstract：OBJECTIVE:To compare urea nitrogen removal by continuous hemodiafiltration vs. functional native kidneys in critically ill, septic patients receiving > 2 g of amino acids/kg body weight per day. DESIGN:Prospective, comparative, unblinded study. SETTING:Trauma critical care units of a Level I adult trauma hospital. P...

journal_title：Critical care medicine

authors： Frankenfield DC,Reynolds HN,Wiles CE 3rd,Badellino MM,Siegel JH

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVE:During cardiopulmonary bypass, inflammation and immunosuppression is present. We measured circulating mediators and monocyte-based functions and tested the hypothesis that these variables are influenced by methylprednisolone (MP) or tirilazad mesylate (TM) treatment. DESIGN:Randomized, controlled, double-bli...

journal_title：Critical care medicine

authors： Volk T,Schmutzler M,Engelhardt L,Döcke WD,Volk HD,Konertz W,Kox WJ

更新日期：2001-11-01 00:00:00

abstract：:Severe complications sometimes occur in critically ill patients during intrahospital transport. Possible causes may be inadequate ventilation, insufficient monitoring, interrupted application of vasoactive drugs, or disconnections and accidental extubation. We constructed a transport unit equipped with a respirator; c...

journal_title：Critical care medicine

authors： Link J,Krause H,Wagner W,Papadopoulos G

更新日期：1990-12-01 00:00:00

abstract：OBJECTIVE:Recent in vivo studies of both septic humans and animals demonstrate that leukocyte delivery is attenuated to sites remote from the primary infection. The mechanisms for this are not entirely clear. L-selectin is integral to rolling, the first step in leukocyte recruitment to an inflammatory site. L-selectin ...

journal_title：Critical care medicine

authors： Ferri LE,Swartz D,Christou NV

更新日期：2001-01-01 00:00:00

abstract：:Thirty-three patients underwent extensive cardiorespiratory monitoring during cardiac surgery. Recordings of measurements, with derived variables, were made preoperatively, postoperatively, and after extubation approximately 3 h after operation. The data provide a reference that allows decisions on whether the conditi...

journal_title：Critical care medicine

authors： Prakash O,Meij S,v d Borden B,Saxena PR

更新日期：1981-07-01 00:00:00

abstract：OBJECTIVE:Surgical trauma results in diffuse sympathoadrenal activation which is thought to contribute to perioperative cardiovascular complications in high-risk patients. Regional anesthetic and analgesic techniques can attenuate this "stress response" and reduce the occurrence rate of adverse perioperative events; ho...

journal_title：Critical care medicine

authors： Dorman T,Clarkson K,Rosenfeld BA,Shanholtz C,Lipsett PA,Breslow MJ

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:We have previously described a method for the precise delivery of inhaled nitric oxide (iNO) via a conventional, continuous-flow, pressure-limited, time-cycled ventilator. Because of the augmented effect of iNO decreasing pulmonary vascular resistance with high-frequency oscillatory ventilation (HFOV), we de...

journal_title：Critical care medicine

authors： Espinosa RM,Marks KH

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVE:To determine whether blood lactate, base deficit, or oxygen-derived hemodynamic variables correlate with morbidity and mortality rates in a clinically-relevant LD50 model of penetrating trauma. DESIGN:Prospective, controlled study. SETTING:University research laboratory. SUBJECTS:Anesthetized, mechanically...

journal_title：Critical care medicine

authors： Moomey CB Jr,Melton SM,Croce MA,Fabian TC,Proctor KG

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:Sepsis is life-threatening organ dysfunction due to dysregulated host responses to infection. Current knowledge of human B-cell alterations in sepsis is sparse. We tested the hypothesis that B-cell loss in sepsis involves distinct subpopulations of B cells and investigated mechanisms of B-cell depletion. DES...

journal_title：Critical care medicine

authors： Shankar-Hari M,Fear D,Lavender P,Mare T,Beale R,Swanson C,Singer M,Spencer J

更新日期：2017-05-01 00:00:00

abstract：:Biological systems are innately complex, display nonlinear behavior, and respond to both disease and its treatment in similar complex ways. Complex systems display self-organization and predictive behavior along a range of possible states, often referred to as chaotic behavior, and can be both characterized and quanti...

journal_title：Critical care medicine

authors： Pinsky MR

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVE:To evaluate partial occlusion in patients with pulmonary hypertension with regard to a) the degree to which it leads to overestimation of pulmonary artery occlusion pressure (Ppao) and b) identification of factors that could enhance its recognition. DESIGN:Observational descriptive study. SETTING:Medical in...

journal_title：Critical care medicine

authors： Leatherman JW,Shapiro RS

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:Sepsis is associated with a marked depression of cellular immune function. The steroid hormone dehydroepiandrosterone (DHEA) is proposed to have immunoenhancing activities. We, therefore, investigated the effect of DHEA on the mortality rate and cellular immune functions in an experimental model of sepsis. D...

journal_title：Critical care medicine

authors： Oberbeck R,Dahlweid M,Koch R,van Griensven M,Emmendörfer A,Tscherne H,Pape HC

更新日期：2001-02-01 00:00:00

abstract：:Twenty-one patients who underwent cardiopulmonary bypass for myocardial revascularization received postoperatively controlled mechanical ventilation (CMV) or intermittent mandatory ventilation (IMV), with or without positive end-expiratory pressure (PEEP). Functional residual capacity (FRC), right-to-left intrapulmona...

journal_title：Critical care medicine

authors： Downs JB,Mitchell LA

更新日期：1976-11-01 00:00:00

abstract：OBJECTIVES:Conflict is common between physicians and surrogate decision makers around end-of-life care in ICU. Involving experts in conflict management improve outcomes, but little is known about what differences in conflict management styles may explain the benefit. We used simulation to examine potential differences ...

journal_title：Critical care medicine

authors： Chiarchiaro J,White DB,Ernecoff NC,Buddadhumaruk P,Schuster RA,Arnold RM

更新日期：2016-05-01 00:00:00

abstract：:In April 2009, Mexican, American, and Canadian authorities announced that a novel influenza virus with pandemic potential had been identified in large segments of the population. Within weeks, it became apparent that the world was dealing with the first influenza pandemic in >40 yrs. Despite the unpredictable nature o...

journal_title：Critical care medicine

authors： Lagacé-Wiens PR,Rubinstein E,Gumel A

更新日期：2010-04-01 00:00:00

abstract：:Perfluorocarbon (PFC) emulsions are promising oxygen-carrying blood supplements for the treatment of shock and in organ preservation for transplantation. We used the isolated, blood-perfused, canine right lower lung lobe (RLL) to determine the effect of a PFC emulsion, Oxypherol (FC-43), upon lung fluid balance and he...

journal_title：Critical care medicine

authors： Hall JE,Ehrhart IC,Hofman WF

更新日期：1985-12-01 00:00:00

abstract：OBJECTIVES:Previous workers have demonstrated that controlled mechanical ventilation results in diaphragm inactivity and elicits a rapid development of diaphragm weakness as a result of both contractile dysfunction and fiber atrophy. Limited data exist regarding the impact of pressure support ventilation, a commonly us...

journal_title：Critical care medicine

authors： Hudson MB,Smuder AJ,Nelson WB,Bruells CS,Levine S,Powers SK

更新日期：2012-04-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to analyze the effect of the International Nosocomial Infection Control Consortium's multidimensional approach on the reduction of ventilator-associated pneumonia in patients hospitalized in intensive care units. DESIGN:A prospective active surveillance before-after study. The stud...

journal_title：Critical care medicine

authors： Rosenthal VD,Rodrigues C,Álvarez-Moreno C,Madani N,Mitrev Z,Ye G,Salomao R,Ulger F,Guanche-Garcell H,Kanj SS,Cuéllar LE,Higuera F,Mapp T,Fernández-Hidalgo R,INICC members.

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:Perfluorocarbon liquid ventilation has been shown to enhance pulmonary mechanics and gas exchange in the setting of respiratory failure. To optimize the total liquid ventilation process, we developed a volume-limited, time-cycled liquid ventilatory support, consisting of an electrically actuated, microprocess...

journal_title：Critical care medicine

authors： Meinhardt JP,Quintel M,Hirschl RB

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVES:To compare sleep, work hours, and behavioral alertness in faculty and fellows during a randomized trial of nighttime in-hospital intensivist staffing compared with a standard daytime intensivist model. DESIGN:Prospective observational study. SETTING:Medical ICU of a tertiary care academic medical center du...

journal_title：Critical care medicine

authors： Bakhru RN,Basner M,Kerlin MP,Halpern SD,Hansen-Flaschen J,Rosen IM,Dinges DF,Schweickert WD

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVES:To measure pulmonary capillary pressure and pulmonary artery occlusion pressures both during control conditions and during acute lung injury and to evaluate the effects of inotropic therapy and volume loading on these measurements after lung injury. DESIGN:Prospective, randomized, controlled laboratory tria...

journal_title：Critical care medicine

authors： Pellett AA,Lord KC,Champagne MS,deBoisblanc BP,Johnson RW,Levitzky MG

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVE:To determine the financial impact of a sepsis protocol designed for use in the emergency department. DESIGN:Retrospective analysis of a before-after study testing the implications of sepsis protocol. SETTING:Academic, tertiary care hospital in the United States. PATIENTS:Persons with septic shock presentin...

journal_title：Critical care medicine

authors： Shorr AF,Micek ST,Jackson WL Jr,Kollef MH

更新日期：2007-05-01 00:00:00

abstract：:In order to examine the prognostic value of pulmonary arterial hypertension (PAH) in patients with moderate and severe acute respiratory failure (ARF), 225 patients with ARF who had been treated with mechanical ventilation and admitted to our ICU during a 3-yr period (January, 1983 to January, 1986) were prospectively...

journal_title：Critical care medicine

authors： Villar J,Blazquez MA,Lubillo S,Quintana J,Manzano JL

更新日期：1989-06-01 00:00:00

abstract：OBJECTIVE:To compare the effects of two different antibiotic regimes on the colonization and infection rates of critically ill pediatric patients. DESIGN:A prospective randomized trial. SETTING:A pediatric ICU in a university hospital. PATIENTS:Fifty critically ill pediatric patients who required intensive care for ...

journal_title：Critical care medicine

authors： Zobel G,Kuttnig M,Grubbauer HM,Semmelrock HJ,Thiel W

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVE:To quantify glucose balance related to continuous arteriovenous hemofiltration (CAVH) when a glucose-rich replacement fluid is used for the plasma ultrafiltrate removed. DESIGN:Prospective, nonintervention study. SETTING:Medical/surgical and cardiac surgical intensive care units of a university hospital. P...

journal_title：Critical care medicine

authors： Monaghan R,Watters JM,Clancey SM,Moulton SB,Rabin EZ

更新日期：1993-08-01 00:00:00

abstract：:Three patients under observation in ICUs developed mechanical upper airway obstruction requiring surgical intervention for airway control. One patient was treated by tracheotomy placed through a vertical midline incision and 2 patients were treated by cricothyroidotomy followed by elective tracheostomy and closure of ...

journal_title：Critical care medicine

authors： Schecter WP,Wilson RS

更新日期：1981-08-01 00:00:00

abstract：OBJECTIVES:To compare the plasma volume (PV) expanding effect of a fast infusion rate with that of a slow infusion rate of a fixed volume of 5% albumin, of the synthetic colloids, 6% hydroxyethyl starch 130/0.4 and 4% gelatin, and of 0.9% NaCl in a rat sepsis model and to compare the plasma-expanding effect among these...

journal_title：Critical care medicine

authors： Bark BP,Persson J,Grände PO

更新日期：2013-03-01 00:00:00

abstract：:Critical care clinicians no longer consider family members as visitors in the intensive care unit. Family-centered care has emerged from the results of qualitative and quantitative studies evaluating the specific needs of families of patients dying in the intensive care unit. In addition, interventional studies have e...

journal_title：Critical care medicine

authors： Lautrette A,Ciroldi M,Ksibi H,Azoulay E

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVES:Given the efficacy and safety of recombinant human activated protein C (rhAPC) in the systemic inflammatory response syndrome, this study was designed to review the evidence for a role for APC in the pathogenesis of preeclampsia. Preeclampsia is a proinflammatory and procoagulant state, and it is a pregnancy...

journal_title：Critical care medicine

authors： von Dadelszen P,Magee LA,Lee SK,Stewart SD,Simone C,Koren G,Walley KR,Russell JA

更新日期：2002-08-01 00:00:00

abstract：OBJECTIVE:To assess clinician perceptions of a machine learning-based early warning system to predict severe sepsis and septic shock (Early Warning System 2.0). DESIGN:Prospective observational study. SETTING:Tertiary teaching hospital in Philadelphia, PA. PATIENTS:Non-ICU admissions November-December 2016. INTERVE...

journal_title：Critical care medicine

authors： Ginestra JC,Giannini HM,Schweickert WD,Meadows L,Lynch MJ,Pavan K,Chivers CJ,Draugelis M,Donnelly PJ,Fuchs BD,Umscheid CA

更新日期：2019-11-01 00:00:00