Effects of hyperventilation on conjunctival oxygen tension in humans.

abstract：OBJECTIVE:Our objective was to quantify the association between intensive care unit-acquired dysglycemia (hyperglycemia, hypoglycemia, and high variability) and in-hospital mortality. DESIGN:Retrospective, observational study. SETTING:eICU Research Institute participating hospitals with an active tele-ICU program bet...

journal_title：Critical care medicine

authors： Badawi O,Waite MD,Fuhrman SA,Zuckerman IH

更新日期：2012-12-01 00:00:00

abstract：OBJECTIVE:To examine the effect of hypertonic saline on bacterial translocation and the number and function of natural killer and T cells in controlled hemorrhagic shock. DESIGN:Randomized controlled study. Duration of follow-up was 24 hrs. SETTING:University research laboratory. SUBJECTS:Adult male Sprague-Dawley r...

journal_title：Critical care medicine

authors： Hirsh M,Dyugovskaya L,Bashenko Y,Krausz MM

更新日期：2002-04-01 00:00:00

abstract：OBJECTIVES:To review mechanisms underlying sepsis-induced cardiac dysfunction in general and intrinsic myocardial depression in particular. DATA SOURCE:MEDLINE database. DATA SYNTHESIS:Myocardial depression is a well-recognized manifestation of organ dysfunction in sepsis. Due to the lack of a generally accepted defi...

journal_title：Critical care medicine

authors： Rudiger A,Singer M

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVES:To evaluate the epidemiology of hyperammonemia unrelated to liver failure in the critical care setting. DESIGN:Retrospective case series. SETTING:Critically ill patients admitted to ICUs at Mayo Clinic, Rochester, MN (medical ICU, two mixed medical-surgical ICUs, coronary care unit, or the cardiosurgical I...

journal_title：Critical care medicine

authors： Sakusic A,Sabov M,McCambridge AJ,Rabinstein AA,Singh TD,Mukesh K,Kashani KB,Cook D,Gajic O

更新日期：2018-09-01 00:00:00

abstract：OBJECTIVE:Sympathetic vasoconstriction regulates peripheral circulation and controls blood pressure, but sepsis is associated with hypotension. We evaluated whether apparent loss of sympathetic vasoconstrictor responsiveness relates to distended smooth muscles or to endotoxemia and/or hypoxia. DESIGN:Prospective descr...

journal_title：Critical care medicine

authors： Brassard P,Zaar M,Thaning P,Secher NH,Rosenmeier JB

更新日期：2016-04-01 00:00:00

abstract：OBJECTIVE:To examine the association between the performance of a tracheostomy and intensive care unit and postintensive care unit mortality, controlling for treatment selection bias and confounding variables. DESIGN:Prospective, observational, cohort study. SETTING:Twelve French medical or surgical intensive care un...

journal_title：Critical care medicine

authors： Clec'h C,Alberti C,Vincent F,Garrouste-Orgeas M,de Lassence A,Toledano D,Azoulay E,Adrie C,Jamali S,Zaccaria I,Cohen Y,Timsit JF

更新日期：2007-01-01 00:00:00

abstract：OBJECTIVES:To investigate the effects of recombinant human erythropoietin on brain oxygenation in a model of diffuse traumatic brain injury. DESIGN:Adult male Wistar rats. SETTING:Neurosciences and physiology laboratories. INTERVENTIONS:Thirty minutes after diffuse traumatic brain injury (impact-acceleration model),...

journal_title：Critical care medicine

authors： Bouzat P,Millet A,Boue Y,Pernet-Gallay K,Trouve-Buisson T,Gaide-Chevronnay L,Barbier EL,Payen JF

更新日期：2013-05-01 00:00:00

abstract：:Bradycardia is common in critical care units. It may be transient, asymptomatic and of little consequence, or life-threatening. Bradycardia may result from abnormalities of the sinus node, atrioventricular node, or the His-Purkinje system. It may also be precipitated by drug effects or enhanced vagal tone. Proper diag...

journal_title：Critical care medicine

authors： Kaushik V,Leon AR,Forrester JS Jr,Trohman RG

更新日期：2000-10-01 00:00:00

abstract：:Standard techniques for measuring pulmonary resistance (RP) to gas flow in newborn infants yield results that are widely dispersed and difficult to interpret. The purpose of this study is to describe and evaluate a new improved method for determining RP which utilizes a sinusoidal pressure wave generator. Measurements...

journal_title：Critical care medicine

authors： Richardson P,Carlstrom JR

更新日期：1983-07-01 00:00:00

abstract：OBJECTIVE:To investigate the effect of early administration of granulocyte colony-stimulating factor (G-CSF) on hospital mortality in nonneutropenic patients with septic shock, excluding patients with melioidosis. DESIGN:A randomized, placebo-controlled, double-blinded clinical trial. SETTING AND PATIENTS:Adult patie...

journal_title：Critical care medicine

authors： Stephens DP,Thomas JH,Higgins A,Bailey M,Anstey NM,Currie BJ,Cheng AC

更新日期：2008-02-01 00:00:00

abstract：:We describe the use of continuous negative extrathoracic pressure to treat successfully the adult respiratory distress syndrome in a 19-yr-old woman who resisted the application of positive airway pressure. Arterial hypoxemia was reversed with -26 cm H2O of extrathoracic pressure, produced by a modified Emerson iron l...

journal_title：Critical care medicine

authors： Morris AH,Elliott CG

更新日期：1985-11-01 00:00:00

abstract：OBJECTIVE:To review the institutional experience of a national tertiary referral center for extracorporeal life support (ECLS) in severe varicella pneumonia. DATA SOURCES:Hospital records and ECLS flow sheets. STUDY SELECTION:All pediatric (nonneonatal) and adult patients who were treated for varicella pneumonia with...

journal_title：Critical care medicine

authors： Lee WA,Kolla S,Schreiner RJ Jr,Hirschl RB,Bartlett RH

更新日期：1997-06-01 00:00:00

abstract：:Clinical impressions about the problem of defibrillation during states of acid-base imbalance and hypoxia have been influenced by studies involving the effect of these derangements on the ventricular fibrillation threshold. Based on body weight, energy requirements for defibrillation in normal dogs were compared to re...

journal_title：Critical care medicine

authors： Yakaitis RW,Thomas JD,Mahaffey JE

更新日期：1975-07-01 00:00:00

abstract：OBJECTIVE:To determine xanthine oxidase activity, free radical concentrations, and lipid peroxidation in patients with sepsis syndrome compared with noninfected critically ill patients. DESIGN:A prospective observational study. SETTING:A nine-bed intensive care unit in a university teaching hospital trust. PATIENTS:...

journal_title：Critical care medicine

authors： Galley HF,Davies MJ,Webster NR

更新日期：1996-10-01 00:00:00

abstract：OBJECTIVE:To determine the effects of accidental injury of varying severity on interleukin (IL)-1 alpha, IL-6, IL-8, tumor necrosis factor-alpha (TNF-alpha), and endotoxin release. DESIGN:Prospective, multi-unit, longitudinal study. SETTING:Emergency Departments and intensive care units of two university hospitals. ...

journal_title：Critical care medicine

authors： Hoch RC,Rodriguez R,Manning T,Bishop M,Mead P,Shoemaker WC,Abraham E

更新日期：1993-06-01 00:00:00

abstract：OBJECTIVE:To evaluate the performance at admission to the pediatric intensive care unit (PICU) of five severity scores, two general (the Pediatric Risk of Mortality [PRISM] II and III scores) and three specific for meningococcal septic shock (Leclerc, Glasgow Meningococcal Septicemia Prognostic Score [GMSPS], and Gedde...

journal_title：Critical care medicine

authors： Castellanos-Ortega A,Delgado-Rodríguez M

更新日期：2000-08-01 00:00:00

abstract：OBJECTIVE:Sepsis and acute lung injury continue to be major causes of morbidity and mortality worldwide despite advances in our understanding of pathophysiology and the discovery of new management strategies. Recent investigations show that stem cells may be beneficial as prognostic biomarkers and novel therapeutic str...

journal_title：Critical care medicine

authors： Cribbs SK,Matthay MA,Martin GS

更新日期：2010-12-01 00:00:00

abstract：OBJECTIVE:To determine risk factors for nosocomial pneumonia in critically ill trauma patients. DESIGN:Prospective cohort study. SETTING:The trauma intensive care unit (ICU) of a 1500-bed tertiary-care hospital. PATIENTS:All critically ill trauma patients (n = 103) admitted consecutively between November 1995 and Oc...

journal_title：Critical care medicine

authors： Tejada Artigas A,Bello Dronda S,Chacón Vallés E,Muñoz Marco J,Villuendas Usón MC,Figueras P,Suarez FJ,Hernández A

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVES:Milrinone is a phosphodiesterase F-III inhibitor with positive inotropic and vasodilating activities. We investigated the hemodynamic response and pharmacokinetics of intravenous milrinone in patients with acute heart failure. DESIGN:Double-blind studies: a prospective, multicenter, double-blind, dose-findi...

journal_title：Critical care medicine

authors： Seino Y,Momomura S,Takano T,Hayakawa H,Katoh K

更新日期：1996-09-01 00:00:00

abstract：OBJECTIVES:To investigate family perceptions of having a nurse participating in family conferences and to assess the psychologic well being of the same families after ICU discharge. DESIGN:Mixed-method design with a qualitative study embedded in a single-center randomized study. SETTING:Twelve-bed medical-surgical IC...

journal_title：Critical care medicine

authors： Garrouste-Orgeas M,Max A,Lerin T,Grégoire C,Ruckly S,Kloeckner M,Brochon S,Pichot E,Simons C,El-Mhadri M,Bruel C,Philippart F,Fournier J,Tiercelet K,Timsit JF,Misset B

更新日期：2016-06-01 00:00:00

abstract：OBJECTIVE:Anecdotal reports suggest that propofol (Diprivan) may stimulate mucus hypersecretion in patients without pulmonary disease. The purpose of this study was to evaluate the effect of methohexital or propofol anesthesia on the physical and transport properties of airway mucus in spontaneously breathing dogs. DE...

journal_title：Critical care medicine

authors： Padda GS,Kishioka C,Rubin BK

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVES:Augmented renal clearance might lead to subtherapeutic plasma levels of drugs with predominant renal clearance. Early identification of augmented renal clearance remains challenging for the ICU physician. We developed and validated our augmented renal clearance predictor, a clinical prediction model for augm...

journal_title：Critical care medicine

authors： Gijsen M,Huang CY,Flechet M,Van Daele R,Declercq P,Debaveye Y,Meersseman P,Meyfroidt G,Wauters J,Spriet I

更新日期：2020-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the safety and physiologic actions of ibuprofen in patients with severe sepsis. DESIGN:Randomized, double-blind, placebo-controlled trial. SETTING:Three university hospital medical ICUs. PATIENTS:Twenty-nine patients with clinical evidence of sepsis and the need for hemodynamic monitoring with ...

journal_title：Critical care medicine

authors： Haupt MT,Jastremski MS,Clemmer TP,Metz CA,Goris GB

更新日期：1991-11-01 00:00:00

abstract：OBJECTIVES:To compare usual care with a proactive case-finding approach for critically ill patients with terminal dementia using an inpatient palliative care service. DESIGN:Prospective comparison to historical control. SETTING:Urban, university-affiliated hospital. PATIENTS:Total of 52 men and women with end-stage ...

journal_title：Critical care medicine

authors： Campbell ML,Guzman JA

更新日期：2004-09-01 00:00:00

abstract：OBJECTIVES:Administration of eicosapentaenoic acid and docosahexanoic acid, omega-3 fatty acids in fish oil, has been associated with improved patient outcomes in acute lung injury when studied in a commercial enteral formula. However, fish oil has not been tested independently in acute lung injury. We therefore sought...

journal_title：Critical care medicine

authors： Stapleton RD,Martin TR,Weiss NS,Crowley JJ,Gundel SJ,Nathens AB,Akhtar SR,Ruzinski JT,Caldwell E,Curtis JR,Heyland DK,Watkins TR,Parsons PE,Martin JM,Wurfel MM,Hallstrand TS,Sims KA,Neff MJ

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To assess the agreement between computed tomography and transcranial sonography in patients after decompressive craniectomy. DESIGN:Prospective study. SETTING:The medical intensive care unit of a university-affiliated teaching hospital. PATIENTS:Thirty head-injured patients consecutively admitted to the in...

journal_title：Critical care medicine

authors： Caricato A,Mignani V,Bocci MG,Pennisi MA,Sandroni C,Tersali A,Antonaci A,de Waure C,Antonelli M

更新日期：2012-06-01 00:00:00

abstract：:Significant resistance was encountered when an attempt was made to withdraw a persistently wedged pulmonary artery catheter. A small amount of air was injected into the balloon lumen with great difficulty. This injection freed the catheter which was removed, but produced significant sudden hemoptysis and a pneumothora...

journal_title：Critical care medicine

authors： Farber DL,Rose DM,Bassell GM,Eugene J

更新日期：1981-06-01 00:00:00

abstract：:Hemodynamic, respiratory, and cerebral variables during 2 h of standard external CPR were studied in 5 dogs. In an additional 12 dogs, possible augmentation of these variables by Military Anti-Shock Trousers (MAST) was evaluated. In 9 dogs, external and internal cardiac massage were compared. During ventricular fibril...

journal_title：Critical care medicine

authors： Bircher N,Safar P,Stewart R

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND:Hypertonic saline is the recommended therapy to shrink swollen brain cells in patients with acute hyponatremia accompanied by seizures. OBJECTIVES:In the absence of hypertonic saline, hypertonic mannitol will shrink the cell volume. Because mannitol is excreted rapidly, our aim was to ensure that it would b...

journal_title：Critical care medicine

authors： Porzio P,Halberthal M,Bohn D,Halperin ML

更新日期：2000-06-01 00:00:00

abstract：OBJECTIVES:Sepsis remains a serious clinical problem despite intensive research efforts and numerous attempts to improve outcome by modifying the inflammatory response. Substance P, the principal ligand for the neurokinin-1 receptor, is a potent proinflammatory mediator that exacerbates inflammatory responses and cardi...

journal_title：Critical care medicine

authors： Mella JR,Chiswick E,Stepien D,Moitra R,Duffy ER,Stucchi A,Remick D

更新日期：2017-02-01 00:00:00