Adult respiratory distress syndrome: successful support with continuous negative extrathoracic pressure.

abstract：OBJECTIVE:Prolonged stay in the intensive care unit (ICU) is associated with high mortality, morbidity, and costs. Identifying those patients who are most likely to benefit from an extended ICU stay would be helpful in guiding clinical decisions. We sought to describe the characteristics and outcomes for a heterogeneou...

journal_title：Critical care medicine

authors： Martin CM,Hill AD,Burns K,Chen LM

更新日期：2005-09-01 00:00:00

abstract：:The effect of positive-pressure ventilation (PPV) with PEEP on the release of alpha-atrial natriuretic peptide (ANP) was investigated in both humans and an experimental model. In the human study, systemic artery blood samples from 22 critically ill patients were analyzed for ANP. Seventeen of these patients received P...

journal_title：Critical care medicine

authors： Teba L,Dedhia HV,Schiebel FG,Blehschmidt NG,Lindner WJ

更新日期：1990-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the effects of continuous infusion of methylene blue (MB), an inhibitor of the nitric oxide pathway, on hemodynamics and organ functions in human septic shock. DESIGN:Prospective, randomized, controlled, open-label, pilot study. SETTING:Multidisciplinary intensive care unit of a university hospi...

journal_title：Critical care medicine

authors： Kirov MY,Evgenov OV,Evgenov NV,Egorina EM,Sovershaev MA,Sveinbjørnsson B,Nedashkovsky EV,Bjertnaes LJ

更新日期：2001-10-01 00:00:00

abstract：OBJECTIVE:Rapid fluid loading is standard treatment for hypovolemia. Because volume expansion does not always improve hemodynamic status, predictive parameters of fluid responsiveness are needed. Passive leg raising is a reversible maneuver that mimics rapid volume expansion. Passive leg raising-induced changes in stro...

journal_title：Critical care medicine

authors： Préau S,Saulnier F,Dewavrin F,Durocher A,Chagnon JL

更新日期：2010-03-01 00:00:00

abstract：:Gastric mucosal damage produced by topical application of necrotizing agents is diminished by topical or systemic pretreatment with a variety of E and F prostaglandins. The rat restraint model of gastric mucosal injury is more analogous to clinical stress ulceration than are models using intragastric application of to...

journal_title：Critical care medicine

authors： Ephgrave KS,Horton J,Burns D

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:To investigate the relationship between nitric oxide production, endotoxemia, and hemodynamic alterations in human septic shock. DESIGN:Prospective study. SETTING:A 32-bed intensive care unit in a university referral hospital. PATIENTS:Two groups of septic patients with shock (n = 13) or without shock (n =...

journal_title：Critical care medicine

authors： Gómez-Jiménez J,Salgado A,Mourelle M,Martín MC,Segura RM,Peracaula R,Moncada S

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVE:To examine the effects of mechanical ventilation with a tidal volume of 6 mL/kg compared with 12 mL/kg predicted body weight on hemodynamics, vasopressor use, fluid balance, diuretics, sedation, and neuromuscular blockade within 48 hrs in patients with acute lung injury and acute respiratory distress syndrome...

journal_title：Critical care medicine

authors： Cheng IW,Eisner MD,Thompson BT,Ware LB,Matthay MA,Acute Respiratory Distress Syndrome Network.

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of spontaneous gasping on cardiorespiratory functions and the ability to resuscitate during experimental cardiac arrest. DATA SOURCES:Studies in rat and pig models during cardiac arrest and cardiopulmonary resuscitation (CPR). STUDY SELECTION:We retrospectively examined the role of sp...

journal_title：Critical care medicine

authors： Yang L,Weil MH,Noc M,Tang W,Turner T,Gazmuri RJ

更新日期：1994-05-01 00:00:00

abstract：OBJECTIVES:Existing handheld glucose meters are glucose oxidase (GO)-based. Oxygen side reactions can introduce oxygen dependency, increase potential error, and limit clinical use. Our primary objectives were to: a) introduce a new glucose dehydrogenase (GD)-based electrochemical biosensor for point-of-care testing; b)...

journal_title：Critical care medicine

authors： Kost GJ,Vu HT,Lee JH,Bourgeois P,Kiechle FL,Martin C,Miller SS,Okorodudu AO,Podczasy JJ,Webster R,Whitlow KJ

更新日期：1998-03-01 00:00:00

abstract：OBJECTIVE:Unplanned readmission of hospitalized patients to an intensive care unit (ICU) is associated with a worse outcome, but our ability to identify who is likely to deteriorate after ICU dismissal is limited. The objective of this study is to develop and validate a numerical index, named the Stability and Workload...

journal_title：Critical care medicine

authors： Gajic O,Malinchoc M,Comfere TB,Harris MR,Achouiti A,Yilmaz M,Schultz MJ,Hubmayr RD,Afessa B,Farmer JC

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:To derive a target range of optimal sedation for the COMFORT Scale and to prospectively test that target range against intensivist assessment of adequacy of sedation. DESIGN:Serial prospective agreement cohort studies. SETTING:Twelve-bed pediatric intensive care unit in an urban academic teaching hospital. ...

journal_title：Critical care medicine

authors： Marx CM,Smith PG,Lowrie LH,Hamlett KW,Ambuel B,Yamashita TS,Blumer JL

更新日期：1994-01-01 00:00:00

abstract：OBJECTIVES:To test whether hospital-based physicians made different intensive care unit and life-sustaining treatment decisions for otherwise identical black and white patients with end-stage cancer and life-threatening hypoxia. DESIGN:We conducted a randomized trial of the relationship between patient race and physic...

journal_title：Critical care medicine

authors： Barnato AE,Mohan D,Downs J,Bryce CL,Angus DC,Arnold RM

更新日期：2011-07-01 00:00:00

abstract：OBJECTIVE:To describe the long-term health-related quality of life (HRQL) of survivors of sepsis and to evaluate the reliability and validity of the medical outcomes study Short Form-36 (SF-36) in this population. STUDY DESIGN:Cross-sectional survey. SETTING:University intensive care unit. PATIENTS:Surviving patient...

journal_title：Critical care medicine

authors： Heyland DK,Hopman W,Coo H,Tranmer J,McColl MA

更新日期：2000-11-01 00:00:00

abstract：:Critical care clinicians no longer consider family members as visitors in the intensive care unit. Family-centered care has emerged from the results of qualitative and quantitative studies evaluating the specific needs of families of patients dying in the intensive care unit. In addition, interventional studies have e...

journal_title：Critical care medicine

authors： Lautrette A,Ciroldi M,Ksibi H,Azoulay E

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:To determine whether four stages of weaning (acute, prewean, wean, and outcome) could be identified by using clinical instruments designed to quantify severity of illness, patient stability, or weaning readiness. The instruments used were the Acute Physiology and Chronic Health Evaluation (APACHE III), the Th...

journal_title：Critical care medicine

authors： Burns SM,Ryan B,Burns JE

更新日期：2000-07-01 00:00:00

abstract：:Transcutaneous PO2 (PtcO2), PaO2, PtcO2 arterial index (ARI; PtcO2/PaO2), and the initial slope index (ISI; [delta PO2/min]/starting PtcO2) were measured in 42 healthy volunteers, 12 patients with stable circulation and respiratory insufficiency, and ten patients with insufficient peripheral circulation in cardiogenic...

journal_title：Critical care medicine

authors： Lemke R,Klaus D,Lübbers DW,Oevermann G

更新日期：1988-04-01 00:00:00

abstract：:The educational objectives in use in our Pediatric ICU are described. These have importance for educational programs in critical care medicine, in particular, where patient care needs can easily overwhelm educational needs. It is important not to overlook our role as teachers in the development of proper attitudes and...

journal_title：Critical care medicine

authors： Kravath RE

更新日期：1977-05-01 00:00:00

abstract：OBJECTIVE:To determine the maternal morbidity and mortality in patients with eclampsia admitted to an intensive care unit (ICU), and to establish the efficacy of the Acute Physiology and Chronic Health Evaluation (APACHE) II score, the organ system failure score as defined by Knaus, and the Glasgow Coma Scale (GCS) sco...

journal_title：Critical care medicine

authors： Bhagwanjee S,Paruk F,Moodley J,Muckart DJ

更新日期：2000-01-01 00:00:00

abstract：OBJECTIVE:After a stay in the intensive care unit, patients risk experiencing delusional memories, memory loss, and symptoms of posttraumatic stress. Since the 1990s, diaries have been kept for intensive care unit patients to help fill in memory gaps, aid psychosocial recovery, and improve health-related quality of lif...

journal_title：Critical care medicine

authors： Egerod I,Christensen D,Schwartz-Nielsen KH,Agård AS

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVE:To assess hemodynamic, tissue oxygenation, and tissue perfusion changes by comparing traditional therapy (fluid resuscitation followed by vasopressor treatment) and alternative therapy (early vasopressor treatment) in a hyperkinetic and sedated model of endotoxic shock. DESIGN:Prospective controlled experime...

journal_title：Critical care medicine

authors： Sennoun N,Montemont C,Gibot S,Lacolley P,Levy B

更新日期：2007-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the relationship between the acute inflammatory response after surgical trauma and changes in hepatic cytochrome P450 3A4 activity, compare changes in cytochrome P450 3A4 activity after procedures with varying degrees of surgical stress, and to explore the time course of any potential drug-cytokin...

journal_title：Critical care medicine

authors： Haas CE,Kaufman DC,Jones CE,Burstein AH,Reiss W

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:Heatstroke requires active body cooling and organ failure supportive care. Although heat waves are expected to recur over the next decades, little is known about the risk factors for mortality in heatstroke patients. We examined the prognosis and risk factors for hospital mortality in patients with heatstroke...

journal_title：Critical care medicine

authors： Misset B,De Jonghe B,Bastuji-Garin S,Gattolliat O,Boughrara E,Annane D,Hausfater P,Garrouste-Orgeas M,Carlet J

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:Critically ill patients often develop large gastric residual volumes during nasogastric feeding as a result of poor gastroduodenal motility. Nasojejunal feeding may decrease the severity of this complication. The aim of this study was to determine whether nasojejunal feeding improved tolerance of enteral nutr...

journal_title：Critical care medicine

authors： Davies AR,Froomes PR,French CJ,Bellomo R,Gutteridge GA,Nyulasi I,Walker R,Sewell RB

更新日期：2002-03-01 00:00:00

abstract：OBJECTIVES:a) To determine whether pentoxifylline has a preventive effect on the decrease in PaO2 that is caused by oleic acid, and whether pentoxifylline facilitates normalization of PaO2 from the decreased state. b) To examine whether pentoxifylline can attenuate an increase in pulmonary vascular permeability that is...

journal_title：Critical care medicine

authors： Moriuchi H,Yuizono T

更新日期：1995-02-01 00:00:00

abstract：OBJECTIVE:During cardiopulmonary bypass, inflammation and immunosuppression is present. We measured circulating mediators and monocyte-based functions and tested the hypothesis that these variables are influenced by methylprednisolone (MP) or tirilazad mesylate (TM) treatment. DESIGN:Randomized, controlled, double-bli...

journal_title：Critical care medicine

authors： Volk T,Schmutzler M,Engelhardt L,Döcke WD,Volk HD,Konertz W,Kox WJ

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVES:Although highly active antiretroviral therapy has led to improved survival in HIV-infected individuals, outcomes for HIV-infected patients with sepsis in the post-highly active antiretroviral therapy era are conflicting. Access to highly active antiretroviral therapy and healthcare disparities continue to af...

journal_title：Critical care medicine

authors： Cribbs SK,Tse C,Andrews J,Shenvi N,Martin GS

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:To elucidate sources of variability in the estimate of treatment effects in a successful phase 3 trial in severe sepsis and to assess their implications on the design of future clinical trials. DESIGN:Retrospective evaluation of prospectively defined subgroups from a large phase 3, placebo-controlled clinica...

journal_title：Critical care medicine

authors： Macias WL,Vallet B,Bernard GR,Vincent JL,Laterre PF,Nelson DR,Derchak PA,Dhainaut JF

更新日期：2004-12-01 00:00:00

abstract：OBJECTIVE:Cardiogenic shock remains an important therapeutic challenge, with high in-hospital mortality rates. Mechanical circulatory support may be beneficial in these patients. Since the efficacy of the intra-aortic balloon pump seems limited, new percutaneously placed mechanical left ventricular support devices, suc...

journal_title：Critical care medicine

authors： Engström AE,Cocchieri R,Driessen AH,Sjauw KD,Vis MM,Baan J,de Jong M,Lagrand WK,van der Sloot JA,Tijssen JG,de Winter RJ,de Mol BA,Piek JJ,Henriques JP

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:The purpose of this study is to: 1) describe a newly mechanism of blood flow to the brain during cardiopulmonary resuscitation using the impedance threshold device in a piglet model of cardiac arrest, and 2) describe the survival benefits in humans of applying all of the highly recommended changes in the 2005...

journal_title：Critical care medicine

authors： Aufderheide TP,Alexander C,Lick C,Myers B,Romig L,Vartanian L,Stothert J,McKnite S,Matsuura T,Yannopoulos D,Lurie K

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVES:To describe the most common serious adverse effects and organ toxicities associated with emerging therapies for cancer that may necessitate admission to the ICU. DATA SOURCES AND STUDY SELECTION:PubMed and Medline search of relevant articles in English on the management of adverse effects of immunotherapy f...

journal_title：Critical care medicine

authors： Gutierrez C,McEvoy C,Munshi L,Stephens RS,Detsky ME,Nates JL,Pastores SM

更新日期：2020-01-01 00:00:00