Dimethyl-prostaglandin E2 prevents stress ulceration with minimal complications.

abstract：OBJECTIVES:In-hospital pediatric sepsis mortality has decreased substantially, but long-term mortality and morbidity among children initially surviving sepsis, is unknown. Accordingly, the Life After Pediatric Sepsis Evaluation investigation was conducted to describe the trajectory of mortality and health-related quali...

journal_title：Critical care medicine

authors： Zimmerman JJ,Banks R,Berg RA,Zuppa A,Newth CJ,Wessel D,Pollack MM,Meert KL,Hall MW,Quasney M,Sapru A,Carcillo JA,McQuillen PS,Mourani PM,Wong H,Chima RS,Holubkov R,Coleman W,Sorenson S,Varni JW,McGalliard J,Haal

更新日期：2020-03-01 00:00:00

abstract：OBJECTIVE:To study whether noninvasive pressure support ventilation (NIPSV) with helium/oxygen (He/oxygen), which can reduce dyspnea, PaCO2, and work of breathing more than NIPSV with air/oxygen in decompensated chronic obstructive pulmonary disease, could have beneficial consequences on outcome and hospitalization cos...

journal_title：Critical care medicine

authors： Jolliet P,Tassaux D,Roeseler J,Burdet L,Broccard A,D'Hoore W,Borst F,Reynaert M,Schaller MD,Chevrolet JC

更新日期：2003-03-01 00:00:00

abstract：OBJECTIVE:After a stay in the intensive care unit, patients risk experiencing delusional memories, memory loss, and symptoms of posttraumatic stress. Since the 1990s, diaries have been kept for intensive care unit patients to help fill in memory gaps, aid psychosocial recovery, and improve health-related quality of lif...

journal_title：Critical care medicine

authors： Egerod I,Christensen D,Schwartz-Nielsen KH,Agård AS

更新日期：2011-08-01 00:00:00

abstract：OBJECTIVES:Increasing age is a well-recognized risk factor for in-hospital mortality in patients receiving extracorporeal membrane oxygenation for cardiogenic shock, but the shape of this relationship is unknown. In addition, the impact of age on hospital length of stay, patterns of patient disposition, and costs has b...

journal_title：Critical care medicine

authors： Chung M,Zhao Y,Strom JB,Shen C,Yeh RW

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:To assess in-hospital neurologic (CNS) complications in adult patients undergoing veno-venous extracorporeal membrane oxygenation for respiratory failure. DESIGN:Retrospective analysis of the Extracorporeal Life Support Organization's data registry. SETTING:Data reported to Extracorporeal Life Support Orga...

journal_title：Critical care medicine

authors： Lorusso R,Gelsomino S,Parise O,Di Mauro M,Barili F,Geskes G,Vizzardi E,Rycus PT,Muellenbach R,Mueller T,Pesenti A,Combes A,Peek G,Frenckner B,Di Nardo M,Swol J,Maessen J,Thiagarajan RR

更新日期：2017-08-01 00:00:00

abstract：OBJECTIVE:We previously reported improved oxygenation, but no change, in rates of extracorporeal membrane oxygenation (ECMO) use or death among infants with persistent pulmonary hypertension of the newborn who received inhaled nitric oxide (NO) with conventional ventilation, irrespective of lung disease. The goal of ou...

journal_title：Critical care medicine

authors： Christou H,Van Marter LJ,Wessel DL,Allred EN,Kane JW,Thompson JE,Stark AR,Kourembanas S

更新日期：2000-11-01 00:00:00

abstract：OBJECTIVE:To determine the significance of moderate elevations of serum troponin I in a surgical intensive care unit patient population in terms of its impact on indexes of outcome including mortality, morbidity, and hospital and intensive care unit length of stay. DESIGN:Retrospective chart review and analysis of cli...

journal_title：Critical care medicine

authors： Relos RP,Hasinoff IK,Beilman GJ

更新日期：2003-11-01 00:00:00

abstract：OBJECTIVE:Trauma induces a complex immune response that requires a systems biology research approach. Here, we used a novel technology, mass cytometry by time-of-flight, to comprehensively characterize the multicellular response to trauma. DESIGN:Peripheral blood mononuclear cells samples were stained with a 38-marker...

journal_title：Critical care medicine

authors： Seshadri A,Brat GA,Yorkgitis BK,Keegan J,Dolan J,Salim A,Askari R,Lederer JA

更新日期：2017-09-01 00:00:00

abstract：:We analyzed 35 samples of fresh frozen plasma (FFP), finding mean concentrations of 535 mg/dl glucose, 172 mEq/L sodium, 73 mEq/L chloride, 3.5 mEq/L potassium, 15 mEq/L bicarbonate, and 5.5 g/dl protein with 60% albumin. Thus, FFP is a hyperosmolal, hyperglycemic, hypernatremic, and hypochloremic solution which may b...

journal_title：Critical care medicine

authors： Ewalenko P,Deloof T,Peeters J

更新日期：1986-02-01 00:00:00

abstract：OBJECTIVE:To determine the maternal morbidity and mortality in patients with eclampsia admitted to an intensive care unit (ICU), and to establish the efficacy of the Acute Physiology and Chronic Health Evaluation (APACHE) II score, the organ system failure score as defined by Knaus, and the Glasgow Coma Scale (GCS) sco...

journal_title：Critical care medicine

authors： Bhagwanjee S,Paruk F,Moodley J,Muckart DJ

更新日期：2000-01-01 00:00:00

abstract：:The tradition of clinical ultrasound in the hands of physicians who provide critical care to the most acutely ill patients stretches back into the 1980s and is rich with experiences from surgical, emergency medicine, and other practices. Now, as critical care ultrasound explodes around the world, it is important to re...

journal_title：Critical care medicine

authors： Kendall JL,Hoffenberg SR,Smith RS

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:Although survival is traditionally modeled using Cox proportional hazards modeling, this approach may be inappropriate in sepsis, in which the proportional hazards assumption does not hold. Newer, more flexible models, such as Gray's model, may be more appropriate. OBJECTIVES:To construct and compare Gray's...

journal_title：Critical care medicine

authors： Kasal J,Jovanovic Z,Clermont G,Weissfeld LA,Kaplan V,Watson RS,Angus DC

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVE:The administration of endotoxin to healthy humans reduces cerebral blood flow but its influence on dynamic cerebral autoregulation remains unknown. We considered that a reduction in arterial carbon dioxide tension would attenuate cerebral perfusion and improve dynamic cerebral autoregulation in healthy subjec...

journal_title：Critical care medicine

authors： Brassard P,Kim YS,van Lieshout J,Secher NH,Rosenmeier JB

更新日期：2012-06-01 00:00:00

abstract：OBJECTIVES:There is limited evidence supporting the widespread use of α2 agonists (clonidine and dexmedetomidine) in pediatric critical care sedation. This study sought to test the association between the use of α2 agonists and enhanced sedation. DESIGN:A retrospective observational cohort study was conducted. Noninfe...

journal_title：Critical care medicine

authors： Hayden JC,Doherty DR,Dawkins I,Leacy FP,Healy M,Breatnach CV,Cousins G,Gallagher PJ

更新日期：2019-07-01 00:00:00

abstract：OBJECTIVES:To determine whether delirium during ICU stay is associated with long-term mental health problems defined as symptoms of anxiety, depression, and posttraumatic stress disorder. DESIGN:Prospective cohort study. SETTING:Survey study, 1 year after discharge from a medical-surgical ICU in the Netherlands. PAT...

journal_title：Critical care medicine

authors： Wolters AE,Peelen LM,Welling MC,Kok L,de Lange DW,Cremer OL,van Dijk D,Slooter AJ,Veldhuijzen DS

更新日期：2016-10-01 00:00:00

abstract：:We report a case of an amniotic fluid embolism (AFE) causing a cardiorespiratory arrest associated temporally with ingestion of castor oil in a full-term normal pregnancy. Risk factors usually associated with AFE were not found in this patient. ...

journal_title：Critical care medicine

authors： Steingrub JS,Lopez T,Teres D,Steingart R

更新日期：1988-06-01 00:00:00

abstract：OBJECTIVE:To determine the influence of a selective, sterile central nervous system surgery on immune reactivity, particularly whether a decrease of monocytic human leukocyte antigen-DR expression, indicating immunodepression, occurs after neurosurgery and if this measurement is useful for identification of patients wi...

journal_title：Critical care medicine

authors： Asadullah K,Woiciechowsky C,Döcke WD,Liebenthal C,Wauer H,Kox W,Volk HD,Vogel S,Von Baehr R

更新日期：1995-12-01 00:00:00

abstract：OBJECTIVE:Although it is established that septic shock induces immunosuppression, the mechanisms for this phenomenon remain poorly understood. Human leukocyte antigen-G exerts strong inhibitory effects that are directed at different arms of the immune system. The main objective of the current study was to measure human...

journal_title：Critical care medicine

authors： Monneret G,Voirin N,Krawice-Radanne I,Bohé J,Lepape A,Rouas-Freiss N,Carosella ED

更新日期：2007-08-01 00:00:00

abstract：OBJECTIVE:To determine whether a correlation exists between concentrations of intracellular and extracellular potassium and to determine the frequency of ventricular ectopy in patients after cardiac operations. DESIGN:Prospective, observational clinical evaluation. SETTING:Surgical-respiratory intensive care unit of ...

journal_title：Critical care medicine

authors： Johnson RG,Shafique T,Sirois C,Weintraub RM,Comunale ME

更新日期：1999-11-01 00:00:00

abstract：PURPOSES:To discuss the theoretical relationship of mean alveolar pressure to its most easily measured analog, the mean airway pressure, and to describe the key determinants, measurement considerations, and clinical implications of this index. DATA SOURCES:Relevant articles from the medical and physiologic literature,...

journal_title：Critical care medicine

authors： Marini JJ,Ravenscraft SA

更新日期：1992-10-01 00:00:00

abstract：:Cardiogenic shock is the most common cause of death in patients hospitalized with acute myocardial infarction and is associated with a poor prognosis. More than 75% of cases are due to extensive left ventricular infarction and ventricular failure. Other causes include right ventricular infarction and papillary muscle ...

journal_title：Critical care medicine

authors： Topalian S,Ginsberg F,Parrillo JE

更新日期：2008-01-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to evaluate the relative frequency of pediatric in-hospital cardiopulmonary resuscitation events occurring in ICUs compared to general wards. We hypothesized that the proportion of pediatric cardiopulmonary resuscitation provided in ICUs versus general wards has increased over the p...

journal_title：Critical care medicine

authors： Berg RA,Sutton RM,Holubkov R,Nicholson CE,Dean JM,Harrison R,Heidemann S,Meert K,Newth C,Moler F,Pollack M,Dalton H,Doctor A,Wessel D,Berger J,Shanley T,Carcillo J,Nadkarni VM,Eunice Kennedy Shriver National Institute

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVES:Despite the universal proliferation of emergency medical services programs throughout the United States since 1970, only a few have ever documented a valid lifesaving effect, particularly in large, urban centers. The purpose of this study was to demonstrate the effect of specialized physician supervision on ...

journal_title：Critical care medicine

authors： Pepe PE,Mattox KL,Duke JH,Fisher PB,Prentice FD

更新日期：1993-09-01 00:00:00

abstract：OBJECTIVES:To determine the incidence of enteral feed intolerance, identify factors associated with enteral feed intolerance, and assess the relationship between enteral feed intolerance and key nutritional and clinical outcomes in critically ill patients. DESIGN:Analysis of International Nutrition Survey database col...

journal_title：Critical care medicine

authors： Heyland DK,Ortiz A,Stoppe C,Patel JJ,Yeh DD,Dukes G,Chen YJ,Almansa C,Day AG

更新日期：2021-01-01 00:00:00

abstract：OBJECTIVES:To measure pulmonary capillary pressure and pulmonary artery occlusion pressures both during control conditions and during acute lung injury and to evaluate the effects of inotropic therapy and volume loading on these measurements after lung injury. DESIGN:Prospective, randomized, controlled laboratory tria...

journal_title：Critical care medicine

authors： Pellett AA,Lord KC,Champagne MS,deBoisblanc BP,Johnson RW,Levitzky MG

更新日期：2002-02-01 00:00:00

abstract：OBJECTIVES:The American College of Critical Care Medicine provided 2002 and 2007 guidelines for hemodynamic support of newborn and pediatric septic shock. Provide the 2014 update of the 2007 American College of Critical Care Medicine "Clinical Guidelines for Hemodynamic Support of Neonates and Children with Septic Shoc...

journal_title：Critical care medicine

authors： Davis AL,Carcillo JA,Aneja RK,Deymann AJ,Lin JC,Nguyen TC,Okhuysen-Cawley RS,Relvas MS,Rozenfeld RA,Skippen PW,Stojadinovic BJ,Williams EA,Yeh TS,Balamuth F,Brierley J,de Caen AR,Cheifetz IM,Choong K,Conway E Jr,Cor

更新日期：2017-06-01 00:00:00

abstract：OBJECTIVE:To determine whether preoperative plasma levels of B-type natriuretic peptide would allow for the prediction of perioperative and early postoperative cardiovascular support requirements and hospital bed usage after coronary artery surgery. DESIGN:A prospective observational cohort study. SETTING:A tertiary ...

journal_title：Critical care medicine

authors： Cuthbertson BH,McKeown A,Croal BL,Mutch WJ,Hillis GS

更新日期：2005-02-01 00:00:00

abstract：OBJECTIVE:To examine the hypothesis that heat stress applied after the administration of bacterial endotoxin is protective. DESIGN:Prospective, randomized, laboratory study. SETTING:University research laboratory. SUBJECTS:One hundred eleven adult male Sprague-Dawley rats (weight range 250 to 400 g). INTERVENTIONS:...

journal_title：Critical care medicine

authors： Chu EK,Ribeiro SP,Slutsky AS

更新日期：1997-10-01 00:00:00

abstract：OBJECTIVE:The goals of this review article are to review the importance and value of standardized definitions in clinical research, as well as to propose the necessary tools and infrastructure needed to advance nosology and medial taxonomy to improve the quality of clinical trials in the field of critical care. DATA S...

journal_title：Critical care medicine

authors： Singh JM,Ferguson ND

更新日期：2009-01-01 00:00:00

abstract：:The current definition of sepsis is life-threatening, acute organ dysfunction secondary to a dysregulated host response to infection. Criteria to operationalize this definition can be judged by six domains of usefulness (reliability, content, construct and criterion validity, measurement burden, and timeliness). The r...

journal_title：Critical care medicine

authors： Seymour CW,Coopersmith CM,Deutschman CS,Gesten F,Klompas M,Levy M,Martin GS,Osborn TM,Rhee C,Warren DK,Watson RS,Angus DC

更新日期：2016-03-01 00:00:00