Mortality of patients with heatstroke admitted to intensive care units during the 2003 heat wave in France: a national multiple-center risk-factor study.

abstract：:Bacterial translocation and ileal and cecal injury have been shown to occur 24 h after limited periods of hemorrhagic shock. The present studies were performed to determine the temporal sequence of mucosal injury, permeability, and bacterial translocation after hemorrhagic shock. The results indicated that bacterial t...

journal_title：Critical care medicine

authors： Deitch EA,Morrison J,Berg R,Specian RD

更新日期：1990-05-01 00:00:00

abstract：OBJECTIVES:To determine how many multicenter, randomized controlled trials have been published that assess mortality as a primary outcome in the adult intensive care unit population, and to evaluate their methodologic quality. DATA SOURCE:A sensitive search strategy for randomized controlled trials was conducted in th...

journal_title：Critical care medicine

authors： Ospina-Tascón GA,Büchele GL,Vincent JL

更新日期：2008-04-01 00:00:00

abstract：OBJECTIVE:We tested whether mild hypothermia impacts on circulatory and respiratory dysfunction during experimental endotoxemia. DESIGN:Randomized controlled prospective experimental study. SETTING:Large animal facility, Medical University of Graz, Austria. SUBJECTS:Thirteen anesthetized and mechanically ventilated ...

journal_title：Critical care medicine

authors： Schwarzl M,Seiler S,Wallner M,von Lewinski D,Huber S,Maechler H,Steendijk P,Zelzer S,Truschnig-Wilders M,Obermayer-Pietsch B,Lueger A,Pieske BM,Post H

更新日期：2013-12-01 00:00:00

abstract：:A commercially available gas-chromatograph (Sentorr Gas Analyzer, Ohio Medical Products, Madison, WI) was tested, featuring continuous measurement of in vivo PaO2 and PaCO2 by means of a thin, heparin-coated catheter, inserted through an indwelling arterial line. Gas tensions are displayed every 4 min. The probes had ...

journal_title：Critical care medicine

authors： Carlon GC,Kahn RC,Ray C Jr,Howland WS

更新日期：1980-07-01 00:00:00

abstract：OBJECTIVES:Severe sepsis poses a major burden on the U.S. healthcare system. Previous epidemiologic studies have not differentiated community-acquired severe sepsis from healthcare-associated severe sepsis or hospital-acquired severe sepsis hospitalizations. We sought to compare and contrast community-acquired severe s...

journal_title：Critical care medicine

authors： Page DB,Donnelly JP,Wang HE

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:Use of antibiotics in critically ill patients may increase the risk of invasive Candida infection. The objective of this study was to determine whether increased exposure to antibiotics is associated with increased prevalence of invasive Candida infection. DESIGN:Substudy using data from a randomized control...

journal_title：Critical care medicine

authors： Jensen JU,Hein L,Lundgren B,Bestle MH,Mohr T,Andersen MH,Løken J,Tousi H,Søe-Jensen P,Lauritsen AØ,Strange D,Petersen JA,Thormar K,Larsen KM,Drenck NE,Helweg-Larsen J,Johansen ME,Reinholdt K,Møller JK,Olesen B,Are

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:To develop a pharmacokinetic-pharmacogenomic population model of morphine in critically ill children with acute respiratory failure. DESIGN:Prospective pharmacokinetic-pharmacogenomic observational study. SETTING:Thirteen PICUs across the United States. PATIENTS:Pediatric subjects (n = 66) mechanically ven...

journal_title：Critical care medicine

authors： Zuppa AF,Benitez GR,Zane NR,Curley MAQ,Bradfield J,Hakonarson H,Gastonguay MS,Moorthy G,Prodell J,Gastonguay MR

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:To examine variations in case-mix, structure, resource use, and outcome performance among teaching and nonteaching intensive care units (ICU). DESIGN:Prospective inception cohort study. PATIENTS:A consecutive sample of 15,297 patients at 35 hospitals, which compared 8,269 patients admitted to 20 teaching IC...

journal_title：Critical care medicine

authors： Zimmerman JE,Shortell SM,Knaus WA,Rousseau DM,Wagner DP,Gillies RR,Draper EA,Devers K

更新日期：1993-10-01 00:00:00

abstract：:The acute effects of controlled O2 therapy on hemodynamics and blood gases were investigated in 22 patients with decompensated chronic obstructive pulmonary disease (COPD). An inspired O2 fraction (FIO2) of 0.24 and 0.28 given to the first 12 patients markedly improved arterial and mixed-venous blood oxygenation with ...

journal_title：Critical care medicine

authors： Lejeune P,Mols P,Naeije R,Hallemans R,Melot C

更新日期：1984-12-01 00:00:00

abstract：OBJECTIVE:The role of family interests in medical decision making is controversial. Physicians who routinely treat incompetent patients may have preferred strategies for addressing family interests as they are encountered in surrogate medical decision making. We sought to determine how physicians view the role of famil...

journal_title：Critical care medicine

authors： Hardart GE,Truog RD

更新日期：2003-07-01 00:00:00

abstract：OBJECTIVE:To test the hypotheses that, for uncontrolled hemorrhagic shock (UHS) in rats, mild hypothermia, compared with normothermia, would increase long-term survival as well as moderate hypothermia, oxygen breathing would increase survival further, and hypothermia and oxygen would mitigate visceral ischemia (dysoxia...

journal_title：Critical care medicine

authors： Takasu A,Stezoski SW,Stezoski J,Safar P,Tisherman SA

更新日期：2000-07-01 00:00:00

abstract：OBJECTIVES:Over-utilization of tests, treatments, and procedures is common for hospitalized patients in ICU settings. American Board of Internal Medicine Foundation's Choosing Wisely campaign tasked professional societies to identify sources of overuse in specialty care practice. The purpose of this study was to assess...

journal_title：Critical care medicine

authors： Kleinpell R,Sessler CN,Wiencek C,Moss M

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVES:To quantitate duplex Doppler measurements of splanchnic perfusion to determine if these measurements are reproducible in euvolemic humans and if such measurements are sensitive to mild degrees of systemic hypovolemia. DESIGN:Prospective, nonrandomized, controlled trial. SETTING:Clinical research center. P...

journal_title：Critical care medicine

authors： Dalton JM,Gore DC,Makhoul RG,Fisher MR,DeMaria EJ

更新日期：1995-03-01 00:00:00

abstract：:Sepsis and resulting multiple system organ failure are the leading causes of mortality in intensive care units. Although it is generally appreciated that rampant, deregulated inflammatory pathways play a major role in sepsis, a comprehensive understanding based on the integrated response of multiple signal transductio...

journal_title：Critical care medicine

authors： Nguyen A,Yaffe MB

更新日期：2003-01-01 00:00:00

abstract：:Total parenteral nutrition (TPN) increases CO2 production (VCO2) in patients on intermittent positive-pressure ventilation who cannot match their CO2 excretion to the CO2 load, leading to an increase in PaCO2. We studied gas exchange and blood gas values in six patients with chronic respiratory failure, who were venti...

journal_title：Critical care medicine

authors： Herve P,Simonneau G,Girard P,Cerrina J,Mathieu M,Duroux P

更新日期：1985-07-01 00:00:00

abstract：:This report is intended to familiarize the reader with the current legislation concerning state definitions of death, the pertinent judicial decisions concerning termination of life support and the current status of medical/ethical committees. However, it is of paramount importance to all health care personnel to beco...

journal_title：Critical care medicine

authors： Wallace-Barnhill G,Roth MD,Briggs BA,Bastron DR,Barrocas A

更新日期：1982-01-01 00:00:00

abstract：OBJECTIVE:This study tested the hypothesis that intra-coronary transfusion of circulation-derived autologous CD34+ cells can improve ischemia-related left ventricular dysfunction in patients with severe diffuse coronary artery disease refractory to medication and unsuitable for coronary intervention. DESIGN:A prospect...

journal_title：Critical care medicine

authors： Lee FY,Chen YL,Sung PH,Ma MC,Pei SN,Wu CJ,Yang CH,Fu M,Ko SF,Leu S,Yip HK

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVES:There has long-been controversy about the possible superiority of norepinephrine compared to dopamine in the treatment of shock. The objective was to evaluate the effects of norepinephrine and dopamine on outcome and adverse events in patients with septic shock. DATA SOURCES:A systematic search of the MEDLI...

journal_title：Critical care medicine

authors： De Backer D,Aldecoa C,Njimi H,Vincent JL

更新日期：2012-03-01 00:00:00

abstract：OBJECTIVE:In rodent models, enhanced formation of nitric oxide and formation of peroxynitrite have been implicated in the pathogenesis of various forms of shock. Here we examined the effect of mercaptoethylguanidine (MEG), an inducible nitric oxide synthase inhibitor and peroxynitrite scavenger, in a severe hemorrhagic...

journal_title：Critical care medicine

authors： Szabó A,Hake P,Salzman AL,Szabó C

更新日期：1999-07-01 00:00:00

abstract：OBJECTIVES:Acinetobacter baumannii complex bacteremia has been identified increasingly in critical patients admitted in ICUs. Notably, A. baumannii complex bacteremia has a high mortality rate, yet the risk factors associated with mortality remain unclear and controversial. DESIGN:Retrospective study. SETTING:All adu...

journal_title：Critical care medicine

authors： Lee HY,Chen CL,Wu SR,Huang CW,Chiu CH

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVES:High physical activity levels are associated with wide-ranging health benefits, disease prevention, and longevity. In the present study, we examined the impact of regular physical exercise on the severity of organ injury and survival probability, as well as characteristics of the systemic immune and metaboli...

journal_title：Critical care medicine

authors： Sossdorf M,Fischer J,Meyer S,Dahlke K,Wissuwa B,Seidel C,Schrepper A,Bockmeyer CL,Lupp A,Neugebauer S,Schmerler D,Rödel J,Claus RA,Otto GP

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:Acute respiratory distress syndrome is occasionally seen in newborn infants due to a severe inflammatory process in the lungs that affects capillary-alveolar permeability, epithelial integrity, and type I and II pneumocyte function. The aim of this study was to investigate the effect of a topically applied nu...

journal_title：Critical care medicine

authors： Ankermann T,Reisner A,Wiemann T,Krams M,Köhler H,Krause MF

更新日期：2005-06-01 00:00:00

abstract：OBJECTIVE:Preliminary experimental data suggest that selective β1-blockers may improve ex vivo cardiac function in animal sepsis. Currently, the effects of esmolol on in vivo cardiac function and on vascular function are unknown. The present study was designed to examine the effects of the β1-selective blocker esmolol ...

journal_title：Critical care medicine

authors： Kimmoun A,Louis H,Al Kattani N,Delemazure J,Dessales N,Wei C,Marie PY,Issa K,Levy B

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:Effective therapies are needed to reverse the increased vascular permeability that characterizes acute inflammatory diseases such as acute lung injury. FTY720 is a pharmaceutical analog of the potent barrier-enhancing phospholipid, sphingosine 1-phosphate. Because both FTY720 and sphingosine 1-phosphate have ...

journal_title：Critical care medicine

authors： Wang L,Sammani S,Moreno-Vinasco L,Letsiou E,Wang T,Camp SM,Bittman R,Garcia JG,Dudek SM

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:To determine whether extreme obesity (morbid obesity; body mass index > or =40 kg/m(2)) is an independent risk factor for death among critically ill patients; this objective is most salient in the subset of patients who sustain a prolonged intensive care unit stay during which the burdens of care imposed by o...

journal_title：Critical care medicine

authors： Nasraway SA Jr,Albert M,Donnelly AM,Ruthazer R,Shikora SA,Saltzman E

更新日期：2006-04-01 00:00:00

abstract：:Percutaneous cholecystostomy was employed successfully as an alternative to cholecystectomy for the treatment of acute cholecystitis with perforation in an elderly woman. The procedure, performed portably in the cardiac care unit, was selected because progressive cardiac and renal decompensation made the patient an ex...

journal_title：Critical care medicine

authors： Longmaid HE 3rd,Bassett JG,Gottlieb H

更新日期：1985-08-01 00:00:00

abstract：:The current investigation describes the morphological and pathophysiological effects of stroma-free hemoglobin solution (SFH) on the liver and kidney. One h after a 75% blood volume exchange in animals receiving 7% SFH, hepatic morphology was normal. Animals whose blood was similarly exchanged with 7% albumin demonstr...

journal_title：Critical care medicine

authors： Friedman HI,DeVenuto F

更新日期：1982-04-01 00:00:00

abstract：:We studied prospectively 40 critically ill neurosurgical patients who required prolonged mechanical ventilation to determine the current incidence of stress-related gastroduodenal erosions and ulcers, and to assess endoscopically the efficacy of acid-reducing prophylactic treatment. Nineteen patients were randomized t...

journal_title：Critical care medicine

authors： Reusser P,Gyr K,Scheidegger D,Buchmann B,Buser M,Zimmerli W

更新日期：1990-03-01 00:00:00

abstract：:The current definition of sepsis is life-threatening, acute organ dysfunction secondary to a dysregulated host response to infection. Criteria to operationalize this definition can be judged by six domains of usefulness (reliability, content, construct and criterion validity, measurement burden, and timeliness). The r...

journal_title：Critical care medicine

authors： Seymour CW,Coopersmith CM,Deutschman CS,Gesten F,Klompas M,Levy M,Martin GS,Osborn TM,Rhee C,Warren DK,Watson RS,Angus DC

更新日期：2016-03-01 00:00:00

abstract：:The ability of ACTH-(1-24) to prolong survival and to extend the deadline for effective blood reinfusion has been studied in a model of lethal hypovolemic shock in the rat. Anesthetized rats were bled to a mean arterial pressure of 18 to 25 mm Hg and then subjected to one of the following iv treatments: a) saline; b) ...

journal_title：Critical care medicine

authors： Guarini S,Tagliavini S,Bazzani C,Ferrari W,Bertolini A

更新日期：1990-08-01 00:00:00