Calcific embolization with infective endocarditis involving the posterior mitral leaflet in a patient with underlying hypertrophic obstructive cardiomyopathy.

Abstract:

:We report a case of infective endocarditis (IE) involving the posterior mitral leaflet (PML) with calcific embolization in a patient with hypertrophic obstructive cardiomyopathy (HOCM). Amongst HOCM patients with IE, the anterior mitral leaflet and basal septal myocardium are almost always involved due to the endocardial damage caused by recurrent outflow obstruction and valvular regurgitation. The management of our patient was complicated by moderate mitral stenosis, repeated calcific embolic strokes, dynamic left ventricular outflow track obstruction, and respiratory failure due to flash pulmonary edema. To our knowledge, this is the first reported case of PML involvement in HOCM presenting in this manner.

journal_name

J Thromb Thrombolysis

authors

Lather N,Niziolek K,Toth P,Harris DM

doi

10.1007/s11239-014-1111-4

subject

Has Abstract

pub_date

2015-02-01 00:00:00

pages

241-4

issue

2

eissn

0929-5305

issn

1573-742X

journal_volume

39

pub_type

杂志文章
  • A review of aspirin resistance; definition, possible mechanisms, detection with platelet function tests, and its clinical outcomes.

    abstract::Aspirin (acetylsalicylic acid) is one of the main therapeutics in prevention of thrombo-embolic vascular events. Its efficiency is proved in the prevention of cardiovascular events. However, antiplatelet effect of aspirin is not absolute in all patients and some patients experience thrombo-embolic events despite aspir...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章,评审

    doi:10.1007/s11239-006-9043-2

    authors: Pamukcu B

    更新日期:2007-06-01 00:00:00

  • Impact of early abciximab administration on myocardial reperfusion in patients with ST-segment elevation myocardial infarction pretreated with 600 mg of clopidogrel before percutaneous coronary intervention.

    abstract::Early rapid platelet inhibition with abciximab before primary percutaneous coronary intervention (PPCI) for ST-segment elevation myocardial infarction (STEMI) is suggested as beneficial. In previous studies on early abciximab administration clopidogrel was administered in cathlab in low loading dose. We investigated t...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1007/s11239-010-0461-9

    authors: Dudek D,Rakowski T,Bartus S,Giszterowicz D,Dobrowolski W,Zmudka K,Zalewski J,Ochala A,Wieja P,Janus B,Dziewierz A,Legutko J,Bryniarski L,Dubiel JS

    更新日期:2010-10-01 00:00:00

  • Aqueous extract of Whitmania pigra Whitman ameliorates ferric chloride-induced venous thrombosis in rats via antioxidation.

    abstract::Whitmania pigra Whitman (W. pigra) has been widely employed in decoction for the treatment of blood stasis syndrome for many years in China. The aim of the present study was to explore the anti-venous thrombosis (VT) mechanism of the aqueous extract of W. pigra (AEW) in rats. Rats were orally administered with AEW. A ...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1007/s11239-020-02337-8

    authors: Li P,Lin B,Tang P,Ye Y,Wu Z,Gui S,Zhan Y,Yang W,Lin B

    更新日期:2020-11-17 00:00:00

  • Aspirin dosing in cardiovascular disease prevention and management: an update.

    abstract::Aspirin has been in use for prevention and management of cardiovascular diseases for several decades. Clinical and epidemiological literature suggests that while net benefits of aspirin in primary prevention of CVDs are less clear, the benefits of aspirin in acute scenarios and secondary prevention settings are well e...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章,评审

    doi:10.1007/s11239-015-1267-6

    authors: Ganjehei L,Becker RC

    更新日期:2015-11-01 00:00:00

  • Mechanisms of venous and arterial thrombosis in heparin-induced thrombocytopenia.

    abstract::Since the reports by Weismann and Tobin in 1958 and Roberts et al. in 1964 called attention to paradoxical thrombosis in patients treated with heparin, the thrombotic aspect of the heparin-induced thrombocytopenia syndrome (HIT) has been emphasized. Yet to this day, the mechanism of thrombosis associated with HIT (HIT...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章,评审

    doi:10.1023/a:1027372901367

    authors: Walenga JM,Jeske WP,Messmore HL

    更新日期:2000-11-01 00:00:00

  • Hormone therapies and vascular outcomes: who is at risk?

    abstract::Postmenopausal hormone replacement therapy (HRT), such as estrogen with a progestin (E+P), is associated with an increased risk of myocardial infarction (MI), stroke, and venous thrombosis. Subgroups of susceptible women for these clinical outcomes have not been clearly identified, although women with a prior history ...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章,评审

    doi:10.1023/B:THRO.0000014601.57424.b8

    authors: Cushman M

    更新日期:2003-08-01 00:00:00

  • Impact of type of thrombolytic agent on in-hospital outcomes in ST-segment elevation myocardial infarction patients in the Middle East.

    abstract::Little is known about the impact of thrombolytic agents on in-hospital outcomes in the Middle East. The objective of this study was to evaluate the impact of thrombolytic agents on in-hospital outcomes in ST-segment elevation myocardial infarction (STEMI) patients in six Middle Eastern countries. Gulf Registry of Acut...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s11239-012-0698-6

    authors: Al-Zakwani I,Ali A,Zubaid M,Panduranga P,Sulaiman K,Abusham A,Almahmeed W,Al-Motarreb A,Al Suwaidi J,Amin H

    更新日期:2012-04-01 00:00:00

  • Markers of coagulation dysfunction and inflammation in diabetic and non-diabetic COVID-19.

    abstract::Coagulation dysfunction and inflammatory status were compared between diabetic and non-diabetic COVID-19 patients. The standardized mean difference (SMD) and its 95% confidence interval (CI) was computed for the difference of inflammatory and hypercoagulability markers. The levels of serum ferritin (standardized mean ...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 信件

    doi:10.1007/s11239-020-02270-w

    authors: Varikasuvu SR,Varshney S,Dutt N

    更新日期:2020-09-05 00:00:00

  • Circadian variations in pathogenesis of ST-segment elevation myocardial infarction: an optical coherence tomography study.

    abstract::Previous studies have reported a circadian variation in the onset of ST-segment elevation myocardial infarction (STEMI). However, underlying mechanisms for the circadian variation have not been fully elucidated. We investigated the relationship between onset of STEMI and the underlying pathology using optical coherenc...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1007/s11239-020-02220-6

    authors: Araki M,Yonetsu T,Kurihara O,Nakajima A,Lee H,Soeda T,Minami Y,Higuma T,Kimura S,Takano M,Yan BP,Adriaenssens T,Boeder NF,Nef HM,Kim CJ,Crea F,Kakuta T,Jang IK

    更新日期:2020-07-10 00:00:00

  • Diabetes mellitus is associated with increased bleeding in pulmonary embolism receiving conventional anticoagulant therapy: findings from a "real-world" study.

    abstract::Bleeding refers to the most important complication during anticoagulation therapy in patients with pulmonary embolism (PE). However, the incidence and risk factors of bleeding in Chinese population with anticoagulant therapy remains unknown. Although diabetes mellitus (DM) has been demonstrated to increase the risk of...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1007/s11239-017-1473-5

    authors: Zhang Z,Zhai Z,Yang Y,Wan J,Xie W,Zhu J,Shen YH,Wang C

    更新日期:2017-05-01 00:00:00

  • The thrombolytic effect of aspirin in animal model.

    abstract:BACKGROUND:The aspirin induced platelet aggregation has been reported to be mediated through the inhibition of platelet prostaglandin synthesis. This compound has also been recently reported to stimulate nitric oxide synthesis in platelets. Since nitric oxide has been reported to produce fibrinogen/fibrinolytic effect,...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1007/s11239-007-0023-y

    authors: Karmohapatra SK,Kahn NN,Sinha AK

    更新日期:2007-10-01 00:00:00

  • Mitochondria and chronic effects of cancer therapeutics: The clinical implications.

    abstract::One of the major mechanisms of action of chemo-radiation is to induce cellular senescence, which exerts crucial roles in age-related pathology. The concept of senescence is evolved, and the novel understanding of senescence-associated reprogramming/stemness has emerged. This new concept emphasizes senescence as not on...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章,评审

    doi:10.1007/s11239-020-02313-2

    authors: Dominic A,Hamilton D,Abe JI

    更新日期:2020-10-20 00:00:00

  • Anticoagulation clinics and patient self-testing for patients on chronic warfarin therapy: A cost-effectiveness analysis.

    abstract::This study was intended to evaluate the cost-effectiveness of anticoagulation clinic care and self-testing for the management of patients on chronic warfarin therapy. Using a 5-year Markov model, we evaluated the health and economic outcomes associated with each of three different anticoagulation management approaches...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1023/a:1018704318655

    authors: Lafata JE,Martin SA,Kaatz S,Ward RE

    更新日期:2000-06-01 00:00:00

  • Soluble P-selectin and vascular endothelial growth factor in steady state sickle cell disease: relationship to genotype.

    abstract::Sickle cell disease (SCD) is characterised by abnormal coagulopathy and angiogenesis although their relationships in two common genotypes, homozygous (HbSS) SCD and sickle-haemoglobin C disease (HbSC), are unexplored. We measured markers of platelet activation (soluble P-selectin [sP-selectin]), fibrinolysis (D-dimer)...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1007/s11239-007-0177-7

    authors: Blann AD,Mohan JS,Bareford D,Lip GY

    更新日期:2008-04-01 00:00:00

  • The association between treatment with heparin and survival in patients with Covid-19.

    abstract::This study investigates the association between the treatment with heparin and mortality in patients admitted with Covid-19. Routinely recorded, clinical data, up to the 24th of April 2020, from the 2075 patients with Covid-19, admitted in 17 hospitals in Spain between the 1st of March and the 20th of April 2020 were ...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s11239-020-02162-z

    authors: Ayerbe L,Risco C,Ayis S

    更新日期:2020-08-01 00:00:00

  • Hyperthyroidism is associated with shortened APTT and increased fibrinogen values in a general population of unselected outpatients.

    abstract::Although clinical evidence supports a plausible association between thyroid disorders and venous thrombosis, reliable evidence is so far lacking on the potential biological mechanisms and neither temporary nor permanent thromboembolic risk factors were constantly identified. We performed a 2-years retrospective analys...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1007/s11239-008-0269-z

    authors: Lippi G,Franchini M,Targher G,Montagnana M,Salvagno GL,Guidi GC,Favaloro EJ

    更新日期:2009-10-01 00:00:00

  • A real world data of dabigatran etexilate: multicenter registry of oral anticoagulants in nonvalvular atrial fibrillation.

    abstract::Atrial fibrillation (AF) is a common cardiac arrhythmia. Dabigatran etixalate (DE) is one of the new oral anticoagulant drugs being used in nonvalvular AF (NVAF). There is no adequate real world data in different populations about DE. The aim of this registry was to evaluate the efficacy and safety of DE Consecutive N...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章,多中心研究

    doi:10.1007/s11239-016-1361-4

    authors: Yavuz B,Ayturk M,Ozkan S,Ozturk M,Topaloglu C,Aksoy H,Şabanoglu C,Tanalp AC,Dal K,Ata N,Yavuz BB

    更新日期:2016-10-01 00:00:00

  • Genetic determinants of platelet response to clopidogrel.

    abstract::Antiplatelet agents are the mainstay treatment in the prevention and management of atherothrombotic complications. However, a substantial interpatient variability in response to clopidogrel has been reported. Furthermore, patients with coronary artery disease and lesser platelet inhibition in response to clopidogrel a...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章,评审

    doi:10.1007/s11239-011-0611-8

    authors: Kubica A,Kozinski M,Grzesk G,Fabiszak T,Navarese EP,Goch A

    更新日期:2011-11-01 00:00:00

  • Venous thrombosis and arteriosclerosis obliterans of lower extremities in a very severe patient with 2019 novel coronavirus disease: a case report.

    abstract::The outbreak of 2019 novel coronavirus disease (COVID-19) began since early December 2019, and has been declared as a public health emergency by the World Health Organization. Due to the hypercoagulable state, blood stasis and endothelial injury, severe patients with COVID-19 are at high risk for thrombosis. We report...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1007/s11239-020-02084-w

    authors: Zhou B,She J,Wang Y,Ma X

    更新日期:2020-07-01 00:00:00

  • Bleeding complications after contemporary pharmacoinvasive therapy for ST elevation myocardial infarction.

    abstract:BACKGROUND:Pharmacoinvasive therapy for the treatment of ST elevation myocardial infarction (STEMI) is a strategy that combines early restoration of coronary flow via pharmacologically induced thrombolysis with subsequent, prompt percutaneous coronary intervention (PCI). Prior studies suggesting a heightened bleeding r...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1007/s11239-005-0344-7

    authors: Gutierrez MJ,Aggarwal A,Gilbert K,Sobel BE,Dauerman HL

    更新日期:2004-12-01 00:00:00

  • Thrombolysis with streptokinase during cardiopulmonary resuscitation: a single center experience and review of the literature.

    abstract:OBJECTIVE:To report our experience with use of thrombolysis with streptokinase during cardiopulmonary resuscitation of patients with cardiac arrest due to myocardial infarction. DESIGN:A case series. METHODS:Thrombolytic therapy (streptokinase) was administered during cardiopulmonary resuscitation of 4 patients with ...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1007/s11239-005-3547-z

    authors: Aliyev F,Habeb M,Babalik E,Karadag B

    更新日期:2005-12-01 00:00:00

  • Antithrombotic therapy for chronic coronary syndrome and atrial fibrillation: less might be more.

    abstract::The best strategy in atrial fibrillation (AF) after > 12 months after an acute coronary syndrome or in patients with chronic coronary syndrome without an indication for interventional revascularization remains unclear. European guidelines generally recommend therapy with oral anticoagulation (OAC) alone, whereas North...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章,meta分析

    doi:10.1007/s11239-019-02007-4

    authors: Wernly B,Bhatt DL,Polzin A,Jung C

    更新日期:2020-02-01 00:00:00

  • Clinical implications of elevated PAI-1 revisited: multiple arterial thrombosis in a patient with essential thrombocythemia and elevated plasminogen activator inhibitor-1 (PAI-1) levels: a case report and review of the literature.

    abstract::Plasminogen activator inhibitor (PAI-1), a member of the serine protein family, is the most active in vivo inhibitor of fibrinolysis induced by plasminogen, tissue plasminogen activator (tPA), and urokinase type plasminogen activator (uPA). While the association between elevated PAI-1 and thrombogenesis has been well ...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章,评审

    doi:10.1023/a:1008907001042

    authors: Senno SL,Pechet L

    更新日期:1999-08-01 00:00:00

  • Adverse outcomes associated with inappropriate direct oral anticoagulant starter pack prescription among patients with atrial fibrillation: a retrospective claims-based study.

    abstract::Direct oral anticoagulant (DOAC) starter packs are designed for unique treatment dosing for acute venous thromboembolism (VTE). Inappropriate use of 30-day DOAC starter packs in patients with atrial fibrillation (AF) may increase the risk for bleeding events given higher dosing in the first 1-3 weeks of treatment. A r...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1007/s11239-020-02358-3

    authors: Feng Y,Pai CW,Seiler K,Barnes GD

    更新日期:2021-01-03 00:00:00

  • Risk factors for intracerebral hemorrhage in patients with COVID-19.

    abstract::Intracerebral hemorrhage (ICH) can be a devastating complication of coronavirus disease (COVID-19). We aimed to assess risk factors associated with ICH in this population. We performed a retrospective cohort study of adult patients admitted to NYU Langone Health system between March 1 and April 27 2020 with a positive...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1007/s11239-020-02288-0

    authors: Melmed KR,Cao M,Dogra S,Zhang R,Yaghi S,Lewis A,Jain R,Bilaloglu S,Chen J,Czeisler BM,Raz E,Lord A,Berger JS,Frontera JA

    更新日期:2020-09-24 00:00:00

  • Primary angioplasty in acute myocardial infarction: does age or race matter?

    abstract:PURPOSE:Recent data suggest substantial variations in the treatment of acute myocardial infarction based on age, race, gender and socioeconomic status. We evaluated the use of primary angioplasty (PA) in acute myocardial infarction (AMI) in elderly and minority patients treated at an urban, teaching hospital. SUBJECTS...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1023/b:thro.0000003326.00180.60

    authors: Regueiro CR,Gill N,Hart A,Crawshaw L,Hentosz T,Shannon RP

    更新日期:2003-04-01 00:00:00

  • Challenges and benefits of an inpatient anticoagulation service: one hospital's experience.

    abstract::While outpatient anticoagulation services (AMS) have existed extensively for a number of years, inpatient AMS have only recently begun to be implemented on a widespread basis. This is in direct response to anticoagulation regulations set forth by entities such as the Joint Commission (TJC) and the Centers for Medicare...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1007/s11239-011-0563-z

    authors: Burnett A,D'Angio R,Earl LE,Garcia D

    更新日期:2011-04-01 00:00:00

  • Impact of a Simple Inexpensive Quality Assurance Effort on Physician's Choice of Thrombolytic Agents and Door-to-Needle Time: Implication for Costs of Management.

    abstract::The objective of this study were to assess the impact of a quality assurance effort on the door-to-needle time and the choice of thrombolytic agent for the management of acute myocardial infarction in the emergency department. The study design involved a prospective collection of data on a series of consecutive patien...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1023/A:1008834230015

    authors: Guidry UA,Paul SD,Vega J,Harris C,Chaturvedi R,O'Gara PT,Eagle KA

    更新日期:1998-05-01 00:00:00

  • Evaluation of the value of rapid D-dimer test in conjunction with cardiac troponin I test for early risk stratification of myocardial infarction.

    abstract::We sought to determine the diagnostic value of a D-dimer test for myocardial infarction (MI). The prospective cohort study was carried in the ED of a university hospital. All included patients were tested for D-dimer and cardiac troponin I (cTnI) on ED admission and additional cTnI 6 h later. AMI was retrospectively c...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章

    doi:10.1007/s11239-010-0469-1

    authors: Chang SS,Lee SH,Wu JY,Ning HC,Chiu TF,Wang FL,Chen JH,Li CH,Lee CC,Chan RC

    更新日期:2010-11-01 00:00:00

  • The pharmacology of novel oral anticoagulants.

    abstract::Anticoagulation for the prevention of stroke is an important aspect of the management of atrial fibrillation. Novel anticoagulants including oral factor Xa inhibitors rivaroxaban and apixaban and the direct thrombin inhibitor dabigatran have emerged as important therapeutic treatment options for prevention of stroke i...

    journal_title:Journal of thrombosis and thrombolysis

    pub_type: 杂志文章,评审

    doi:10.1007/s11239-013-0967-z

    authors: DeWald TA,Becker RC

    更新日期:2014-01-01 00:00:00