Abstract：
:Previous studies indicated that connective tissue attachment to the root surface appeared to be dependent upon a chronologic healing sequence related to fibrin and collagen interactions. It was the purpose of the present study to try and substantiate this hypothesis by using histologic techniques designed to differentiate between fibrin and collagen during healing at the root surface interface. In four squirrel monkeys, 24 normal teeth were extracted and reimplanted after either (i) surgically denuding the coronal root surface of connective tissue fibers and cementum by root planing or, (ii) surgical denudation followed by topical application of citric acid (pH = 1; 3 minutes). Three specimens were available for histological analysis 1, 3, 7 and 21 days after reimplantation. Mallory's phosphotungstic acid hematoxylin staining technique was used to differentiate between fibrin and collagen. Epithelium migrated rapidly along the denuded, non-acid-treated, root surfaces, had reached the alveolar crest at 3 days, and was within the ligament space to the level of root denudation at 21 days. Epithelium did not migrate apically along denuded root surfaces treated with citric acid. At 1 and 3 days, inflammatory cells were enmeshed in a fibrin network which appeared to be attached to the root surface by arcade-like structures. At 7 and 21 days, the region had repopulated with connective tissue cells, and collagen fibers had replaced the fibrin. It was concluded that collagen fiber attachment to the root surface was preceded by fibrin linkage, and that the linkage process occurred as an initial event in the wound healing response.
journal_name
J Periodontoljournal_title
Journal of periodontologyauthors
Polson AM,Proye MPdoi
10.1902/jop.1983.54.3.141subject
Has Abstractpub_date
1983-03-01 00:00:00pages
141-7issue
3eissn
0022-3492issn
1943-3670journal_volume
54pub_type
杂志文章abstract：BACKGROUND:The aim of this split-mouth study is to compare long-term (18 to 35 years) periodontal conditions of sites treated with gingival augmentation procedures (GAPs) and untreated homologous contralateral sites. METHODS:Forty-seven patients with 64 sites (test group), with lack of attached gingiva associated with...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2016.160284
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:There is limited information regarding marginal bone-level changes around immediately loaded implants placed with the osteotome technique. The aim of this case series is to prospectively evaluate the clinical and radiographic outcome of immediately loaded implants placed with the osteotome technique over a 1...
journal_title：Journal of periodontology
pub_type： 临床试验,杂志文章
doi：10.1902/jop.2011.100751
更新日期：2011-11-01 00:00:00
abstract：BACKGROUND:The present study was designed to evaluate the effect, if any, of citric acid root demineralization in the outcome of subepithelial connective tissue grafts performed to cover localized gingival recessions. METHODS:Thirty-six patients participated, each providing one gingival recession; 19 received citric a...
journal_title：Journal of periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1902/jop.2000.71.4.568
更新日期：2000-04-01 00:00:00
abstract：BACKGROUND:Macrophages account for 5% to 30% of the inflammatory infiltrate in periodontitis and are activated by the classic and alternative pathways. These pathways are identified by indirect markers, among which interferon (IFN)-γ and interleukin-6 (IL)-6 of the classic pathway and IL-4 of the alternative pathway ha...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2013.130078
更新日期：2014-05-01 00:00:00
abstract：:The purpose of this study was to clinically evaluate the effectiveness of polytetrafluoroethylene membranes in the healing of interproximal Class II furcation defects in maxillary molars using a surgical treatment technique based on the principles of guided tissue regeneration. Eight subjects with similar bilateral Cl...
journal_title：Journal of periodontology
pub_type： 临床试验,杂志文章
doi：10.1902/jop.1998.69.9.1020
更新日期：1998-09-01 00:00:00
abstract：BACKGROUND:The purpose of this case series study was to evaluate posterior single-tooth implant survival and the long-term conditions of the adjacent teeth. METHODS:A retrospective evaluation of 1,162 consecutive patients with a single missing posterior tooth treated with 1,377 external hex implants supporting 1,365 r...
journal_title：Journal of periodontology
pub_type： 杂志文章,多中心研究
doi：10.1902/jop.2008.080188
更新日期：2008-12-01 00:00:00
abstract：:In the first section of this two-part report human peripheral blood leukocytes were tested for reactivity to extracts of sclera. Absence of scleral antigenicity is suggested by the results which showed that the leukocytes reacted similarly in sclera stimulated cultures and in the controls. The second part of the repor...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1980.51.4.211
更新日期：1980-04-01 00:00:00
abstract：SCOPE:These Guidelines apply to products used to promote the regeneration of periodontal tissues lost due to periodontal diseases or other causes. Periodontal regeneration is defined histologically as regeneration of the tooth's supporting tissues, including alveolar bone, periodontal ligament, and cementum over a prev...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1998.69.9.1081
更新日期：1998-09-01 00:00:00
abstract：:The aims of this paper are to briefly describe laser physics, the types of lasers currently available for use on soft tissues focusing primarily on CO2 and Nd:YAG laser energies, the histological effects of lasers on oral tissues, laser safety, the clinical applications of lasers on oral soft tissues, and future direc...
journal_title：Journal of periodontology
pub_type： 杂志文章,评审
doi：10.1902/jop.1993.64.7.589
更新日期：1993-07-01 00:00:00
abstract：BACKGROUND:The pathogenesis of epithelial thickening in gingival overgrowth remains obscure. Apoptosis plays an important role in maintaining tissue hemostasis. The aim of the present study was to investigate apoptosis via immunohistochemical analyses in cyclosporin A-induced gingival overgrowth tissue samples to deter...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2007.070226
更新日期：2007-12-01 00:00:00
abstract：BACKGROUND:T and B lymphocytes play important roles in periodontitis. Smoking is considered a risk factor for periodontitis and may exert its negative effects through leukocytes. Taking smoking into consideration, the aim of this study was to analyze numbers of circulating T (CD3+) cells and their CD4+ and CD8+ subpopu...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2004.75.4.557
更新日期：2004-04-01 00:00:00
abstract：BACKGROUND:Receptor activator of nuclear factor-kappa B (NF-kappaB) ligand (RANKL) and osteoprotegerin (OPG) are critical for homeostatic control of osteoclast activity, suggesting their vital roles in the progression of bone loss in periodontitis. In this study, the expression of RANKL and OPG mRNA and the relationshi...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2007.060398
更新日期：2007-06-01 00:00:00
abstract：BACKGROUND:Collagen barrier membranes are commonly applied in periodontal and bone-regenerative procedures. Membranes differ in their resorption pattern following implantation, thus influencing clinical outcome. The purpose of this study was to quantitatively evaluate the biodegradation of three different commercially ...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2008.070361
更新日期：2008-05-01 00:00:00
abstract：BACKGROUND:No information exists on periodontitis-associated subgingival microbiota from Turkey. We determined the occurrence, interspecies relationships, and clonal characteristics for a group of periodontal bacteria in a Turkish study population. METHODS:Subgingival microbial samples were obtained from patients with...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2003.74.6.803
更新日期：2003-06-01 00:00:00
abstract：BACKGROUND:Surgical crown lengthening has been proposed as a means of facilitating restorative procedures and preventing periodontal injuries in teeth with structurally inadequate clinical crowns or exposing tooth structure in the presence of deep, subgingival pathologies which may hamper the access for proper restorat...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2001.72.7.841
更新日期：2001-07-01 00:00:00
abstract：BACKGROUND:It has been shown that lowering the concentration of chlorhexidine (CHX) in mouthrinses from 0.2% to 0.12% does not adversely affect inhibition of plaque accumulation. The aim of this study was to evaluate the inhibition of plaque growth by 2 commercially available mouthrinses used according to the manufactu...
journal_title：Journal of periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1902/jop.2003.74.2.214
更新日期：2003-02-01 00:00:00
abstract：:The aim of this controlled clinical trial was to assess the effect on healing following tetracycline (TTC) conditioning and fibrin-fibronectin sealing system (FFSS) application in association with flap debridement surgery (FDS) in 11 patients under treatment for moderate to severe periodontitis. Selection criteria inc...
journal_title：Journal of periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1902/jop.1996.67.7.688
更新日期：1996-07-01 00:00:00
abstract：BACKGROUND:The objectives of this study were to: 1) test hypotheses that behavioral factors, baseline clinical status, and incident tooth loss are significantly associated with attachment loss incidence (ALI) and 2) quantify the effect of incident tooth loss on conclusions made about ALI. METHODS:The Florida Dental Ca...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2005.76.7.1161
更新日期：2005-07-01 00:00:00
abstract：BACKGROUND:Gingival augmentation procedures around natural teeth and dental implants are performed to facilitate plaque control, to improve patient comfort, to prevent future recession, and in conjunction with restorative, orthodontic, or prosthetic dentistry. The aim of this study is to answer the most common question...
journal_title：Journal of periodontology
pub_type： 杂志文章,评审
doi：10.1902/jop.2015.130684
更新日期：2015-02-01 00:00:00
abstract：:Gingival incisions were performed distal to each of the two lower incisors on 25 adult male guinea pigs. For every animal, electrosection with an electrosurgical scalpel was used on one side, and a conventional scalpel was used on the other. The surgical instruments in all cases were brought into direct contact with p...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1975.46.1.40
更新日期：1975-01-01 00:00:00
abstract：BACKGROUND:Periodontal disease is a major complication of type 1 diabetes mellitus (T1DM). The aim of the present study is to investigate the relationship between glycated hemoglobin and circulating levels of interleukin (IL)-6, IL-8, and C-X-C motif chemokine ligand 5 (CXCL5) in non-smoking patients suffering from T1D...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2015.150149
更新日期：2015-11-01 00:00:00
abstract：BACKGROUND:Pain generated by needle sticks (Ns) for the delivery of local anesthetic and/or scaling and root planing (SRP) instrumentation is commonly addressed by the use of topical anesthetics, such as a benzocaine-gel preparation (BGP). Pain suppression following such use has been highly variable. Development of med...
journal_title：Journal of periodontology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1902/jop.2001.72.4.479
更新日期：2001-04-01 00:00:00
abstract：BACKGROUND:Controversy over the long-term clinical effectiveness of hydroxyapatite (HA)-coated dental implants still persists, despite numerous clinical studies documenting high survival rates. Concerns about the degradation of the coating over the years have been raised; it has been speculated that resorption of the H...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.2007.060271
更新日期：2007-05-01 00:00:00
abstract：:Experimentation in animal models has created a basis for highly improved therapeutic procedures in reconstructive periodontal surgery. This symposium has discussed several animal models currently used; additional models have been described in recent literature. The presentations by Drs. Caton, Wikesjö, and Lynch illus...
journal_title：Journal of periodontology
pub_type： 评论,杂志文章
doi：10.1902/jop.1994.65.12.1169
更新日期：1994-12-01 00:00:00
abstract：:Oral polymorphonuclear leukocytes (pmn) were obtained from 10 adult donors in good oral health using a method employing repeated mouth rinse collection. Interleukin-1β (IL-1β) mRNA was detected in freshly obtained cells by blot hybridization of total cellular RNA with a biotin labeled cDNA probe. Supernates from oral ...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1995.66.9.761
更新日期：1995-09-01 00:00:00
abstract：BACKGROUND:The purpose of this multicenter randomly controlled clinical trial was to compare two acellular dermal matrix (ADM) materials produced by different processing techniques, freeze-dried (FDADM) and solvent-dehydrated (SDADM) ADM, in their ability to correct Miller Class I and II recession defects. METHODS:Eig...
journal_title：Journal of periodontology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1902/jop.2014.140198
更新日期：2014-12-01 00:00:00
abstract：:This study investigated a possible association between bruxism and severity of periodontal disease. Subjects consisted of 51 patients (mean age 47.3 years) referred to the Department of Periodontology for treatment of moderate to severe periodontal disease (Perio-group) and 40 patients (mean age 48.9 years) referred t...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1987.58.3.173
更新日期：1987-03-01 00:00:00
abstract：:Osseous grafting techniques represent one mode of therapy to manage combination pocket-osseous defects. They have their greatest applicability in the intrabony defect although encouraging results have been noted in furcation and suprabony sites. Like all treatment modalities, their usage is dictated by the therapeutic...
journal_title：Journal of periodontology
pub_type： 杂志文章,评审
doi：10.1902/jop.1977.48.9.570
更新日期：1977-09-01 00:00:00
abstract：:A surgical and suturing method is described for the subgingival placement of Gore-tex periodontal material during new attachment procedures. The periodontal material isolates the root surface from epithelium and gingival connective tissue. Three cases were treated. Clinical new attachment was evident from clinical pro...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1987.58.12.819
更新日期：1987-12-01 00:00:00
abstract：:THIS INVESTIGATION was undertaken to determine the distribution pattern and readability level of 20 widely distributed printed items containing periodontal health education literature. Average annual distribution was obtained from distributors of the material. The Minnesota Interactive Readability Approximation Progra...
journal_title：Journal of periodontology
pub_type： 杂志文章
doi：10.1902/jop.1983.54.9.538
更新日期：1983-09-01 00:00:00
