Discussion: animal models in reconstructive therapy.

Abstract:

:Experimentation in animal models has created a basis for highly improved therapeutic procedures in reconstructive periodontal surgery. This symposium has discussed several animal models currently used; additional models have been described in recent literature. The presentations by Drs. Caton, Wikesjö, and Lynch illustrated the need for further discussion of some of the problems inherent in animal experimentation, including: standardization of periodontal defect configuration; adequate recording of preoperative attachment level; minimizing the effect of biological variability; use of surgically-created versus naturally-developed periodontal lesions; choice of observation period; and regenerative potential of the model chosen.

journal_name

J Periodontol

authors

Selvig KA

doi

10.1902/jop.1994.65.12.1169

subject

Has Abstract

pub_date

1994-12-01 00:00:00

pages

1169-72

issue

12

eissn

0022-3492

issn

1943-3670

journal_volume

65

pub_type

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