Localization of 3H-estradiol-17beta in diethylstilbestrol-induced adenosis.

Abstract:

:Treatment of neonatal mice with diethylstilbestrol results in the appearance of adenosis in the uterine cervix and upper part of the vagina in later life. Using dry mount autoradiography, the uptake and distribution of [3H]-estradiol in the same regions were studied after in vivo injections with [3H]-estradiol. It was demonstrated that the adenosis cells have the ability of uptake and nuclear concentration of estradiol and are thus target cells for estrogens. The importance of this finding for the development of malignancy is discussed in relation to the clear cell adenocarcinomas in young women exposed to diethylstilbestrol in utero.

journal_name

Obstet Gynecol

authors

Kalland T,Fossberg TM,Forsberg JG

doi

10.1097/00006250-197804000-00016

subject

Has Abstract

pub_date

1978-04-01 00:00:00

pages

464-7

issue

4

eissn

0029-7844

issn

1873-233X

journal_volume

51

pub_type

杂志文章
  • Transurethral bladder eversion concurrent with uterovaginal prolapse.

    abstract:BACKGROUND:Transurethral bladder eversion is rare. A case of transurethral bladder eversion with concurrent uterovaginal prolapse is presented. CASE:The patient was postmenopausal, had a long history of uterovaginal prolapse, and developed bladder eversion. Examination under anesthesia revealed full-thickness transure...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(01)01669-6

    authors: Mastropietro MA,Clark MH,Hale DS

    更新日期:2002-05-01 00:00:00

  • The epidemiology of pregnancy complications and outcome in a Norwegian twin population.

    abstract:OBJECTIVE:To measure the contribution of genetic factors to selected pregnancy complications, including miscarriage, twinning, hypertension-toxemia, and nausea-vomiting. METHODS:Information on 22,241 pregnancies of 8675 female twins or spouses of male twins was obtained by questionnaire from members of the population-...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Corey LA,Berg K,Solaas MH,Nance WE

    更新日期:1992-12-01 00:00:00

  • Calcium supplementation in mild preeclampsia remote from term: a randomized double-blind clinical trial.

    abstract:OBJECTIVE:To determine whether calcium supplementation prevents progression to severe disease in preterm nulliparous women with mild preeclampsia. METHODS:Seventy-five women hospitalized at 24-36 weeks' gestation because of mild preeclampsia were randomized to receive either 2 g/day of elemental calcium (36 women) or ...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/0029-7844(95)00052-s

    authors: Sanchez-Ramos L,Adair CD,Kaunitz AM,Briones DK,Del Valle GO,Delke I

    更新日期:1995-06-01 00:00:00

  • Alternative Colposcopy Techniques: A Systematic Review and Meta-analysis.

    abstract:OBJECTIVE:To assess the diagnostic value of alternative (digital) colposcopy techniques for detection of cervical intraepithelial neoplasia (CIN) 2 or worse in a colposcopy population. DATA SOURCES:MEDLINE, EMBASE, ClinicalTrials.gov, and the Cochrane Library were searched from inception up to January 11, 2016, for st...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/AOG.0000000000001613

    authors: Hermens M,Ebisch RMF,Galaal K,Bekkers RLM

    更新日期:2016-10-01 00:00:00

  • Intravenous leiomyomatosis with cardiac extension: successful surgical management and histopathologic study.

    abstract::A case of intravenous leiomyomatosis with cardiac extension was treated successfully with a two-stage operation: resection of the intracardiac and intracaval mass for the first stage and total hysterectomy with bilateral salpingo-oophorectomy for the second. Tumors were located either within or in continuity to dilate...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Suginami H,Kaura R,Ochi H,Matsuura S

    更新日期:1990-09-01 00:00:00

  • Sciatic nerve injury during gynecologic procedures using the lithotomy position.

    abstract::Injury to the sciatic nerve is an infrequent but important complication of gynecologic procedures in which the lithotomy position is used. This lesion may occur after vaginal hysterectomy or after short procedures such as dilatation and curettage or laparoscopy. Few reports are found in the gynecologic literature. The...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Batres F,Barclay DL

    更新日期:1983-09-01 00:00:00

  • Peripheral subcutaneous vulvar stimulation in the management of severe and refractory vulvodynia.

    abstract:BACKGROUND:Vulvodynia is a complex and multifactorial clinical condition with severe pain that occurs in the absence of visible infectious, inflammatory, neoplastic, or neurological findings. CASE:A 35-year-old woman with 3 years of dysesthetic vulvodynia tried conventional and interventional medical treatment with in...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/aog.0b013e31827c60f8

    authors: De Andres J,Sanchis-Lopez N,Asensio-Samper JM,Fabregat-Cid G,Dolz VM

    更新日期:2013-02-01 00:00:00

  • Effect of mifepristone for symptomatic leiomyomata on quality of life and uterine size: a randomized controlled trial.

    abstract:OBJECTIVE:To assess the effect of low-dose mifepristone on quality of life, pain, bleeding, and uterine size among women with symptomatic leiomyomata. METHODS:Forty-two women with symptomatic uterine leiomyomata and uterine volume of 160 mL or more were randomized to mifepristone, 5 mg daily, or placebo for 26 weeks. ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/01.AOG.0000243776.23391.7b

    authors: Fiscella K,Eisinger SH,Meldrum S,Feng C,Fisher SG,Guzick DS

    更新日期:2006-12-01 00:00:00

  • Elevated second-trimester maternal serum hCG: a marker of inadequate angiogenesis.

    abstract:OBJECTIVE:To measure angiogenin, a potent inducer of neovascularization and interleukin-6, as an indicator of acute inflammation, in second-trimester amniotic fluid of patients with elevated maternal serum hCG. METHODS:In this case-control study, 20 patients with elevated maternal serum hCG (at least 2.0 multiples of ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(98)00010-6

    authors: Spong CY,Ghidini A,Dildy GA,Loucks CA,Varner MW,Pezzullo JC

    更新日期:1998-04-01 00:00:00

  • Drive times to hospitals with perinatal care in the United States.

    abstract:OBJECTIVE:To evaluate access to inpatient obstetric care, we determined the proportions of women of reproductive age who resided within 30-minute and 60-minute driving times to the nearest hospital offering perinatal services. METHODS:Perinatal centers, identified from the 2007 American Hospital Association survey, we...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e318242b4cb

    authors: Rayburn WF,Richards ME,Elwell EC

    更新日期:2012-03-01 00:00:00

  • The case-control study: a primer for the obstetrician-gynecologist.

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:

    authors: Peipert JF,Grimes DA

    更新日期:1994-07-01 00:00:00

  • Intraabdominal calcification in treated disseminated carcinoma of the ovary.

    abstract::The presence of diffuse abdominal calcification in patients with known carcinoma is usually a sign of metastatic involvement. This finding in some patients who have been treated with high dosage radiation therapy may represent areas of tumor necrosis and subsequent healing without evidence of active malignancy. ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Menuck L

    更新日期:1977-01-01 00:00:00

  • The genetics of intersexuality: clinical and theoretic perspectives.

    abstract::Recent studies using newly devised serologic techniques have dramatically advanced our understanding of gonadal organogenesis and aberrant sexual differentiation. Thus XY gonadal dysgenesis, XX male syndrome, and XX true hermaphroditism, for example, may be seen as typifying specific errors of regulation, synthesis, o...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:

    authors: Wachtel SS

    更新日期:1979-12-01 00:00:00

  • A rapid colorimetric AFP monoclonal antibody test for the diagnosis of preterm rupture of the membranes.

    abstract::Premature rupture of the membranes is a common and serious complication of pregnancy. Despite the prevalence and severity of sequelae, current diagnostic techniques are less than ideal. We studied 48 women with preterm rupture of the membranes with a rapid, colorimetric monoclonal alpha-fetoprotein (AFP) antibody test...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Rochelson BL,Rodke G,White R,Bracero L,Baker DA

    更新日期:1987-02-01 00:00:00

  • Prenatal detection of ischemic changes in the placenta of the growth-retarded fetus by Doppler flow velocimetry of the maternal uterine artery.

    abstract:OBJECTIVE:To determine the relationships among the pregnancy outcomes of growth-retarded fetuses, Doppler flow velocimetry of the fetomaternal circulation, and pathologic changes in the placenta. METHODS:Forty-seven fetuses confirmed to be growth-retarded by ultrasonographic biometry were monitored during pregnancy in...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Iwata M,Matsuzaki N,Shimizu I,Mitsuda N,Nakayama M,Suehara N

    更新日期:1993-10-01 00:00:00

  • Vulvovaginal pellagra and lichen sclerosus complicating carcinoid syndrome.

    abstract:BACKGROUND:Pellagra is a rare clinical syndrome caused by niacin deficiency, and although most commonly nutritional in origin, may be secondary to carcinoid syndrome. CASE:A premenopausal nulliparous woman with metastatic carcinoid tumor developed isolated vulvovaginal manifestations characterized by well-demarcated s...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e318191bb51

    authors: Reichman O,Sobel JD

    更新日期:2009-02-01 00:00:00

  • Efficacy and safety of intrapartum electronic fetal monitoring: an update.

    abstract:OBJECTIVE:To compare the efficacy and safety of routine electronic fetal monitoring (EFM) of labor with intermittent auscultation, using the results of published randomized controlled trials (RCTs). DATA SOURCES:We identified RCTs by searching the MED-LINE data base for the period 1966-1994, contacting experts, and re...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:

    authors: Thacker SB,Stroup DF,Peterson HB

    更新日期:1995-10-01 00:00:00

  • Experience with midtrimester abortion.

    abstract::The midtrimester abortion program at a large community hospital was evaluated. During the 3-year study, 1839 patients aborted in the midtrimester by intraamniotic injection of hypertonic saline, prostaglandin F2alpha or a combination of saline and prostaglandin F2alpha. The method, using a combination of saline and pr...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Pahl IR,Lundy LE

    更新日期:1979-05-01 00:00:00

  • Nonstress test and maternal serum glucose determinations.

    abstract::Serum glucose levels were measured in 50 nondiabetic pregnant women between 33 and 43 weeks' gestation following a nonstress test (NST) to determine the relationship between maternal glucose levels and the results of the NST. Two comparable groups of 25 patients each were formed based on the NST results, reactive and ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Phelan JP,Kester R,Labudovich ML

    更新日期:1982-10-01 00:00:00

  • First-trimester ultrasonographic screening for trisomy 21 using fetal nuchal translucency and nasal bone.

    abstract:OBJECTIVE:To report our experience with first-trimester screening for trisomy 21 by using the combination of nuchal translucency thickness and nasal bone assessment. METHODS:Pregnant women from a predominantly Latin American population consisting of patients at both low risk and high risk for chromosomal defects under...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000259311.87056.5e

    authors: Sepulveda W,Wong AE,Dezerega V

    更新日期:2007-05-01 00:00:00

  • Pelvic exenteration, University of Michigan: 100 patients at 5 years.

    abstract::One hundred patients undergoing pelvic exenteration (total 69, anterior 13, posterior 18) at the University of Michigan Medical Center from 1964-1984 are reported. All patients were followed for at least 5 years or until time of death. The overall cumulative survival was 66% at 3 years and 61% at 5 years. The age of t...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Morley GW,Hopkins MP,Lindenauer SM,Roberts JA

    更新日期:1989-12-01 00:00:00

  • Risk of Peripartum Hysterectomy and Center Hysterectomy and Delivery Volume.

    abstract:OBJECTIVE:To characterize where women at risk for and undergoing peripartum hysterectomy delivered in terms of obstetric volume and procedural experience. METHODS:We used data from the Perspective database to retrospectively evaluate trends in peripartum hysterectomy and deliveries at high risk of peripartum hysterect...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000001722

    authors: Govindappagari S,Wright JD,Ananth CV,Huang Y,DʼAlton ME,Friedman AM

    更新日期:2016-12-01 00:00:00

  • Comparison of 12- and 72-hour expectant management of premature rupture of membranes in term pregnancies.

    abstract:OBJECTIVE:To compare 12-hour and 72-hour expectant management of premature rupture of membranes (PROM) in singleton term pregnancies. METHODS:In a prospective, nonrandomized study, 566 low-risk women with singleton term pregnancies presenting with PROM were assigned to either 12-hour or 72-hour expectant management. P...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0029-7844(95)00031-l

    authors: Shalev E,Peleg D,Eliyahu S,Nahum Z

    更新日期:1995-05-01 00:00:00

  • The effect of glucagon on spontaneous contractility of isolated pregnant uterine muscle.

    abstract:OBJECTIVE:To determine whether glucagon has relaxant effects on the spontaneous contractions of term pregnant human uterine smooth muscle in an isolated preparation. METHODS:Myometrial specimens were excised from the upper incisional surface of the lower uterine segment in seven women during elective cesarean delivery...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0029-7844(96)00283-9

    authors: Shin YK,Collea JV,Kim YD

    更新日期:1996-11-01 00:00:00

  • The effect of corticosteroid administration on uterine activity and preterm labor in high-order multiple gestations.

    abstract:OBJECTIVE:To determine if corticosteroid administration causes increased contractions or labor in high-order multiple gestations. METHODS:Medical records of all triplet and quadruplet pregnancies cared for by Phoenix Perinatal Associates from August 1988 to January 1992 were reviewed retrospectively. Twenty-one women ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0029-7844(94)00355-H

    authors: Elliott JP,Radin TG

    更新日期:1995-02-01 00:00:00

  • The effect of angiotensin II and indomethacin on uterine artery blood flow in pregnant monkeys.

    abstract::In experiments performed in anesthetized monkeys in the third trimester of pregnancy, mean maternal arterial blood pressure was continuously monitored, the uterine artery blood flow was measured with an electromagnetic flow probe, and prostaglandin levels were assayed in the uterine venous effluent. After inhibition o...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Speroff L,Haning RV Jr,Levin RM

    更新日期:1977-11-01 00:00:00

  • Newly diagnosed adult-onset Still disease in pregnancy.

    abstract:BACKGROUND:Adult-onset Still disease is a rare febrile disorder that can present for the first time during pregnancy. It is a diagnosis of exclusion with nonspecific laboratory results. Good maternal and fetal outcomes can be expected after initial diagnosis and treatment. CASE:A 21-year-old (gravida 2, para 1) at 20 ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(03)00065-6

    authors: Pan VL,Haruyama AZ,Guberman C,Kitridou RC,Wing DA

    更新日期:2003-05-01 00:00:00

  • Ovarian carcinoma: a multivariate analysis of prognostic factors.

    abstract::Five hundred and fifty six women with invasive epithelial ovarian carcinoma were assessed for postoperative treatment between 1966 and 1976. The records of this group were reviewed retrospectively. Sixteen characteristics of the patient and tumor were analyzed for prognostic significance by univariate and multivariate...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Swenerton KD,Hislop TG,Spinelli J,LeRiche JC,Yang N,Boyes DA

    更新日期:1985-02-01 00:00:00

  • Synchronous primary ovarian and endometrial cancers: a population-based assessment of survival.

    abstract:OBJECTIVE:To estimate the occurrence of synchronous epithelial ovarian and endometrial cancers among ovarian cancer patients and to assess survival of women with synchronous cancers. METHODS:Synchronous ovarian and endometrial cases were identified using data from the Surveillance, Epidemiology, and End Results Progra...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e31819c7bdf

    authors: Williams MG,Bandera EV,Demissie K,Rodríguez-Rodríguez L

    更新日期:2009-04-01 00:00:00

  • Factors affecting the consistent use of barrier methods of contraception.

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    pub_type: 杂志文章,评审

    doi:10.1016/0029-7844(96)00245-1

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    更新日期:1996-09-01 00:00:00