Localization of 3H-estradiol-17beta in diethylstilbestrol-induced adenosis.

Abstract:

:Treatment of neonatal mice with diethylstilbestrol results in the appearance of adenosis in the uterine cervix and upper part of the vagina in later life. Using dry mount autoradiography, the uptake and distribution of [3H]-estradiol in the same regions were studied after in vivo injections with [3H]-estradiol. It was demonstrated that the adenosis cells have the ability of uptake and nuclear concentration of estradiol and are thus target cells for estrogens. The importance of this finding for the development of malignancy is discussed in relation to the clear cell adenocarcinomas in young women exposed to diethylstilbestrol in utero.

journal_name

Obstet Gynecol

authors

Kalland T,Fossberg TM,Forsberg JG

doi

10.1097/00006250-197804000-00016

subject

Has Abstract

pub_date

1978-04-01 00:00:00

pages

464-7

issue

4

eissn

0029-7844

issn

1873-233X

journal_volume

51

pub_type

杂志文章
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    abstract::A day in obstetric-gynecologic practice in Kenya involves uterine rupture and other conditions resulting from inadequate care and facilities for labor, as well as infected abortions. Technology and equipment taken for granted in America either don't exist or don't work. Although practice is primitive in many ways, som...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Blumenthal PD

    更新日期:1990-07-01 00:00:00

  • Umbilical cord plasma cortisol levels in association with pregnancy complications.

    abstract::Cortisol concentrations in umbilical cord plasma at birth were determined in association with pregnancy complications which may affect the time of pulmonary maturation of the fetus or otherwise influence its survival. No statistically significant change in these cortisol levels was observed in either term or premature...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Sybulski S

    更新日期:1977-09-01 00:00:00

  • Neonatal outcomes after gestational exposure to nitrofurantoin.

    abstract:OBJECTIVE:To estimate whether first-trimester exposure to nitrofurantoin is associated with increased malformation rates and, secondarily, to estimate whether exposure to nitrofurantoin is associated with increased rates of negative pregnancy outcomes and perinatal complications. METHODS:We conducted a population-base...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e31827c5f88

    authors: Nordeng H,Lupattelli A,Romøren M,Koren G

    更新日期:2013-02-01 00:00:00

  • Severe preeclampsia and high frequency of genetic thrombophilic mutations.

    abstract:OBJECTIVE:To determine whether severe preeclampsia is associated with genetic thrombophilic mutations or other types of thrombophilia. METHODS:A case-control study compared 63 consecutive women with severe preeclampsia evaluated at our institution between November 1997 and April 1999 with 126 control women matched for...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(00)00861-9

    authors: Kupferminc MJ,Fait G,Many A,Gordon D,Eldor A,Lessing JB

    更新日期:2000-07-01 00:00:00

  • Barriers to Evidence-Based Transgender Care: Knowledge Gaps in Gender-Affirming Hysterectomy and Oophorectomy.

    abstract::Reversal of gender-discriminatory insurance coverage policies has led to a substantial increase in access to gender-affirming surgical care in the United States over the past 20 years. Although the evidence supports the safety, feasibility, and medical necessity of gender-affirming hysterectomy and oophorectomy, there...

    journal_title:Obstetrics and gynecology

    pub_type: 社论

    doi:10.1097/AOG.0000000000003472

    authors: Reilly ZP,Fruhauf TF,Martin SJ

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  • ACOG Practice Bulletin Number 131: Screening for cervical cancer.

    abstract::The incidence of cervical cancer in the United States has decreased more than 50% in the past 30 years because of widespread screening with cervical cytology. In 1975, the rate was 14.8 per 100,000 women. By 2008, it had been reduced to 6.6 per 100,000 women. Mortality from the disease has undergone a similar decrease...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,实务指引

    doi:10.1097/aog.0b013e318277c92a

    authors: Committee on Practice Bulletins—Gynecology.

    更新日期:2012-11-01 00:00:00

  • Death from pseudomembranous enterocolitis.

    abstract::During the past 2 years at the Los Angeles County-University of Southern California Medical Center (LAC-USC), there have been 2 deaths from pseudomembranous enterocolitis. Each of these deaths occurred postoperatively in previously healthy women who received pronlonged antibiotic prophylasix. The implications of these...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/00006250-197506000-00002

    authors: Ledger WJ,Puttler OL

    更新日期:1975-06-01 00:00:00

  • Amenorrhea related to progestin excess in congenital adrenal hyperplasia.

    abstract::Studies of the cause of amenorrhea in a patient with congenital adrenal hyperplasia (CAH) whose androgen levels were easily controlled suggested that inhibition of menses in CAH is more closely related to overproduction of progestins than to overproduction of androgens. Supporting this concept was the observation in a...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Rosenfield RL,Bickel S,Razdan AK

    更新日期:1980-08-01 00:00:00

  • Inhibition of premature labor by terbutaline.

    abstract::Terbutaline was administered to 50 women, all diagnosed as being in labor prior to 36 weeks' gestation. In 47, uterine activity was initially arrested with intravenous therapy. The infusion rate required to arrest uterine activity ranged from 10 to 80 microgram/min and 21 of the 50 patients (42%) required more than on...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/00006250-197804000-00001

    authors: Wallace RL,Caldwell DL,Ansbacher R,Otterson WN

    更新日期:1978-04-01 00:00:00

  • Conservative management of a bleeding renal angiomyolipoma in pregnancy.

    abstract:BACKGROUND:Bleeding angiomyolipomas in pregnancy are rare but may be devastating and potentially fatal. In previous cases, most of these lesions have been managed with urgent nephrectomy or embolization. Only one other case report describes treating these lesions through conservative management and vaginal delivery. C...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000167392.59472.c3

    authors: Storm DW,Mowad JJ

    更新日期:2006-02-01 00:00:00

  • Preeclampsia and Long-term Risk of Maternal Retinal Disorders.

    abstract:OBJECTIVE:To evaluate whether preeclampsia is associated with risk of maternal retinal disease in the decades after pregnancy. METHODS:We carried out a longitudinal cohort study of 1,108,541 women who delivered neonates in any hospital in Quebec, Canada, between 1989 and 2013. We tracked women for later hospitalizatio...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000001758

    authors: Auger N,Fraser WD,Paradis G,Healy-Profitós J,Hsieh A,Rhéaume MA

    更新日期:2017-01-01 00:00:00

  • Head-to-cervix forces and their relationship to the outcome of labor.

    abstract::The force (as distinct from pressure) between the fetal head and the maternal cervix during labor was measured for the first time in an attempt to improve the intrapartum prediction of progress in labor. The 50th percentile of the variables active pressure and active force and the mean uterine activity integral were c...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Gough GW,Randall NJ,Genevier ES,Sutherland IA,Steer PJ

    更新日期:1990-04-01 00:00:00

  • Endocervical strip biopsy instrument: an alternative to endocervical curettage.

    abstract::The endocervical strip biopsy instrument obtains strips of endocervical epithelium with attached cervical stroma without excessive bleeding or discomfort to the patient. The intact specimen allows a precise histologic evaluation of endocervical disease processes in patients with abnormal cervical cytology or endometri...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Ostergard DR

    更新日期:1980-11-01 00:00:00

  • Thumbtack use for control of presacral bleeding, with description of an instrument for thumbtack application.

    abstract::There is well-known difficulty in controlling hemorrhage from presacral vessels. There are reports on the use of thumbtacks to secure hemostasis in the face of presacral hemorrhage. This communication reports the successful use of thumbtacks to establish presacral hemostasis and describes a simple instrument designed ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Timmons MC,Kohler MF,Addison WA

    更新日期:1991-08-01 00:00:00

  • Intimate partner violence and maternal cigarette smoking before and during pregnancy.

    abstract:OBJECTIVE:To determine the association of intimate partner violence with maternal cigarette smoking before and during pregnancy. METHODS:Data were obtained for 196,391 U.S. mothers who delivered live neonates from 2004-2008 and completed the Pregnancy Risk Assessment Monitoring System survey 2-9 months postpartum. Int...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000000609

    authors: Cheng D,Salimi S,Terplan M,Chisolm MS

    更新日期:2015-02-01 00:00:00

  • Cocaine, pregnancy, and postpartum intracerebral hemorrhage.

    abstract::An increase in cocaine abuse by pregnant women has been associated with a range of maternal/fetal cardiovascular complications. Intracerebral hemorrhage has been reported as a cocaine-related complication, but has not previously been associated with pregnancy. We report a case of cocaine-associated intracerebral hemor...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Mercado A,Johnson G Jr,Calver D,Sokol RJ

    更新日期:1989-03-01 00:00:00

  • Reactions of residency directors to primary care requirements in obstetrics and gynecology training.

    abstract:OBJECTIVE:To determine the opinions of obstetrics and gynecology residency program directors regarding the Residency Review Committee mandate, requires 6 months of primary care training in obstetrics and gynecology. METHODS:A ten-question survey was mailed to the 272 accredited obstetrics and gynecology programs in th...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(97)00600-5

    authors: Kuffel ME,Stovall DW,Kuffel TS,Zlatnik FJ

    更新日期:1998-01-01 00:00:00

  • Silicone band sterilization with radiographic and laparoscopic evaluation.

    abstract::Laparoscopic tubal sterilization, using a Silastic band to occlude the tubal lumen, was performed on 224 patients. The incidence of complications was low and only 2 pregnancies occurred. Further evaluation by hysterosalpingography on 97 patients revealed 2 distinct images. The site of tubal occlusion was seen on lapar...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Beck P,Gal D,Tancer ML

    更新日期:1979-06-01 00:00:00

  • Medicaid pregnancy termination funding and racial disparities in congenital anomaly-related infant deaths.

    abstract:OBJECTIVE:To explore whether state restrictions on Medicaid funding for pregnancy termination of anomalous fetuses could be contributing to the black-white disparity in infant death resulting from congenital anomalies. METHODS:Data on deaths resulting from anomalies were obtained from U.S. vital statistics records (19...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000000583

    authors: Hutcheon JA,Bodnar LM,Simhan HN

    更新日期:2015-01-01 00:00:00

  • Urinary prostacyclin and thromboxane metabolites in drinking pregnant women and in their infants: relations to the fetal alcohol effects.

    abstract::To study the effect of maternal ethanol consumption on the production of prostacyclin and thromboxane, we measured urinary 6-keto-prostaglandin F1 alpha (a hydration product of prostacyclin), 2,3-dinor-6-keto-prostaglandin F1 alpha (generated from 6-keto-prostaglandin F1 alpha through beta oxidation), and thromboxane ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Ylikorkala O,Halmesmäki E,Viinikka L

    更新日期:1988-01-01 00:00:00

  • The case-control study: a primer for the obstetrician-gynecologist.

    abstract::Case-control studies begin at the end. Two groups of patients, those with disease (cases) and those without (controls), are compared to determine the degree of exposure to a presumed risk factor. This research method is commonly used to study rare diseases or diseases that take years to develop. If a higher proportion...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:

    authors: Peipert JF,Grimes DA

    更新日期:1994-07-01 00:00:00

  • Factors contributing to the accuracy in diagnosing ovarian malignancy by color Doppler ultrasound.

    abstract:OBJECTIVE:To determine whether resistance index values obtained by color Doppler ultrasound contribute to the accuracy in diagnosing ovarian malignancies. METHODS:Four hundred ten patients with ovarian neoplasms referred for color Doppler ultrasound evaluation were enrolled, excluding patients examined during the lute...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Wu CC,Lee CN,Chen TM,Lai JI,Hsieh CY,Hsieh FJ

    更新日期:1994-10-01 00:00:00

  • Tubal pregnancy with normal hysterosalpingogram and negative serum pregnancy test.

    abstract::A patient undergoing evaluation for primary infertility with regular menses had a normal hysterosalpingogram in the follicular phase and underwent diagnostic laparoscopy the next day, with the finding of a tubal pregnancy. The patient had a negative serum pregnancy test. Although a normal hysterosalpingogram and negat...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Uribe MA,Dunn RC,Buttram VC Jr

    更新日期:1990-03-01 00:00:00

  • Early evaluation of the urinary tract following radical hysterectomy: structure and function relationships.

    abstract::One hundred ten consecutive patients with invasive gynecologic cancers, treated by radical hysterectomy at The University of California, Irvine Medical Center, underwent early postoperative intravenous pyelogram (IVP). An abnormal early postoperative IVP did not predict subsequent urinary tract dysfunction (anatomical...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Buller RE,Tamir IL,DiSaia PJ,Berman ML

    更新日期:1991-11-01 00:00:00

  • Evaluation of amniotic fluid alpha-fetoprotein using an enzyme-linked immunosorbent assay.

    abstract::A simple, inexpensive enzyme-linked immunosorbent assay using commercially available supplies is described. An examination of amniotic fluid alpha-fetoprotein (AFP) values for 15 to 20 weeks' gestation is presented. The interassay coefficient of variation was 12% (N = 40) at a level of 4.75 micrograms/mL. Repeat freez...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Bogart MH,Winkelbauer D,Jones OW

    更新日期:1985-09-01 00:00:00

  • Prenatal diagnosis of true diphallia and associated anomalies.

    abstract:BACKGROUND:Diphallia poses several surgical, psychological, and esthetic issues. Currently, diphallia is only diagnosed after birth. CASE:We present a true diphallia in one fetus of dichorionic twins noted at 23 weeks of gestation. In this fetus, two phallus-like protrusions and a bifid scrotum, as well as a duplicate...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000000327

    authors: Tu YA,Su YN,Yang PK,Shih JC

    更新日期:2014-08-01 00:00:00

  • Association of Pharmacist Prescription of Hormonal Contraception With Unintended Pregnancies and Medicaid Costs.

    abstract:OBJECTIVE:To estimate unintended pregnancies averted and the cost effectiveness of pharmacist prescription of hormonal contraception. METHODS:A decision-analytic model was developed to determine the cost effectiveness of expanding the scope of pharmacists to prescribe hormonal contraception compared with the standard ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000003265

    authors: Rodriguez MI,Hersh A,Anderson LB,Hartung DM,Edelman AB

    更新日期:2019-06-01 00:00:00

  • Transplacental passage of vancomycin in noninfected term pregnant women.

    abstract:OBJECTIVE:To evaluate the transplacental passage of vancomycin in term, uninfected pregnant women. METHODS:A single vancomycin 1-g dose was administered intravenously at four separate time intervals to 13 uncomplicated nonlaboring women undergoing scheduled cesarean delivery. Samples of maternal blood and fetal cord b...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000260388.78339.b6

    authors: Laiprasert J,Klein K,Mueller BA,Pearlman MD

    更新日期:2007-05-01 00:00:00

  • Uterine contraction pressures with oxytocin induction/augmentation.

    abstract::Uterine contraction pressures were quantified (in Montetevideo units) in 109 women at term gestation who received oxytocin for induction or augmentation of labor and whose labor resulted in a spontaneous vaginal delivery. Newborn five-minute Apgar scores were greater than or equal to 8 in 108 of the 109 neonates, and ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/00006250-198609000-00003

    authors: Hauth JC,Hankins GD,Gilstrap LC 3rd,Strickland DM,Vance P

    更新日期:1986-09-01 00:00:00

  • Plasma catecholamines and angiotensin-converting enzyme activity in hypertensive subjects with positive rollover tests.

    abstract::The rollover test is useful in predicting and identifying subjects developing hypertensive disorders of pregnancy. The mechanisms responsible for positive tests are unclear, but a greater release of pressor substances occurring in subjects with positive tests has been proposed. The authors measured and compared heart ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Lee MI,Todd HM

    更新日期:1984-04-01 00:00:00