Preinduction cervical ripening with prostaglandin E2 intracervical gel.

Abstract:

:A double-blind, placebo-controlled, dose-ranging study was undertaken to evaluate the efficacy of two doses of intracervical prostaglandin E2 gel in patients with unfavorable Bishop scores. Mean change in Bishop score, success of softening, time to labor, and time to delivery were all significantly different in the two treatment groups as compared with the placebo group. Twenty-three of 30 treated patients had uterine contractions lasting greater than four hours and eight patients delivered during the observation period. Moreover, one case of uterine hyperactivity and five cases of severe fetal heart rate decelerations were noted in the treatment groups. Although efficacious for cervical ripening, caution is warranted when using this technique in patients at risk for placental insufficiency.

journal_name

Obstet Gynecol

authors

Laube DW,Zlatnik FJ,Pitkin RM

subject

Has Abstract

pub_date

1986-07-01 00:00:00

pages

54-7

issue

1

eissn

0029-7844

issn

1873-233X

journal_volume

68

pub_type

临床试验,杂志文章
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    doi:

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