The effect of maternal blood contamination on amniotic fluid glucose and white blood cell count from preterm gestations.

Abstract:

OBJECTIVE:To determine the influence of maternal blood contamination on amniotic fluid (AF) glucose and white blood cell count (WBC). METHODS:Amniotic fluid from 23 preterm, nondiabetic pregnant women was studied. Maternal blood was added to the AF at increasing concentrations, and glucose and WBCs were assessed. RESULTS:The median AF glucose in the uncontaminated specimen was 43 mg/dL (range 11-86). Median glucose levels were unchanged by the addition of maternal blood until a mean +/- standard deviation AF red blood cell count of 63,000 +/- 22,000/mm3 was exceeded, at which time the median glucose level significantly increased to a median of 45 mg/dL (range 19-90). The ratio of observed to expected values of WBCs ranged from 0.12-1.8, regardless of the level of maternal blood contamination. CONCLUSION:Glucose levels in preterm AF-containing maternal blood are accurate in all except the most heavily contaminated specimens. Accurate determination of the WBC in contaminated AF is difficult.

journal_name

Obstet Gynecol

authors

Carlan SJ,Gearity DE,O'Brien WF,Roth L

doi

10.1016/0029-7844(95)00354-1

subject

Has Abstract

pub_date

1996-02-01 00:00:00

pages

185-7

issue

2

eissn

0029-7844

issn

1873-233X

pii

0029-7844(95)00354-1

journal_volume

87

pub_type

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