Abstract：
:A chemotherapeutic combination consisting of VM-26-vincristine-cisplatin was used to treat 44 consecutive patients with primary advanced or recurrent endometrial carcinomas. Nine complete remissions (20.5%) and 14 partial remissions (31.8%) were recorded. The median duration of remission in responders was 8 months (range 1-35). The responding patients had significantly longer survival than nonresponders. The median duration of survival in the complete series was 7 months. The response rates and survival times were the same for primary advanced tumors and recurrences, regardless of sites. Peripheral neuropathy, secondary anemia, and nausea were the most common side effects. The drug combination was well tolerated, and its efficacy is comparable to that of other more toxic chemotherapy regimens.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Sorbe B,Wolmesjö E,Frankendal Bsubject
Has Abstractpub_date
1989-03-01 00:00:00pages
343-8issue
3 Pt 1eissn
0029-7844issn
1873-233Xjournal_volume
73pub_type
杂志文章abstract：:A 31-year-old patient with incomplete testicular feminization syndrome characterized by a 46, XY karyotype in a phenotypic female with absent müllerian structures, marked clitoromegaly, testes and wolffian duct structures, partial labioscrotal fold fusion, and male levels of circulating androgens is described. She was...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1977-01-01 00:00:00
abstract：:Although vaginal laceration following sexual trauma is a well-reported entity, vaginal evisceration appears to be a rare occurrence. This paper presents 2 cases of vaginal evisceration recently managed at the Bronx Municipal Hospital Center and a review of the literature. Etiologic factors and management are discussed...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1975-03-01 00:00:00
abstract：BACKGROUND:Rates of administration of intravenous sodium fluorescein during cystoscopy have increased since indigotindisulfonate sodium was removed from the market in 2014. Although sodium fluorescein has been extensively evaluated and found to be safe, side effects including anaphylaxis have been observed, with an inc...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000002519
更新日期：2018-04-01 00:00:00
abstract：:Individuals with Down syndrome have abnormally short long bones. Sonography has previously revealed slightly shortened femurs and thickened nuchal folds in affected second-trimester fetuses. Humeral and femoral lengths and nuchal folds were evaluated in 400 normal second-trimester controls and in 24 consecutive Down s...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/00006250-199102000-00012
更新日期：1991-02-01 00:00:00
abstract：OBJECTIVE:To estimate the patterns of care and outcome of women with early cervical cancer in the United States based on surgical or radiation intent-to-treat principles. METHODS:The Surveillance, Epidemiology, and End Results 1995 public-use file was the data source. Subjects between the ages of 15 and 80 years at di...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(00)01117-0
更新日期：2001-02-01 00:00:00
abstract：:A randomized prospective study compared the efficacy of a three-dose perioperative course of intravenously administered cefuroxime and metronidazole versus suction drainage of the vaginal vault for preventing postoperative infection in abdominal and vaginal hysterectomies. In vaginally operated patients, a significant...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1987-09-01 00:00:00
abstract：:Uncontrolled lipid peroxidation may play an important role in the pathophysiology of preeclampsia by causing vascular endothelial cell dysfunction. Sera contain antioxidant mechanisms that serve to control lipid peroxidation. We tested the hypothesis that the sera antioxidant protective mechanisms are diminished in wo...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-06-01 00:00:00
abstract：:The Perinatal Quality Foundation and the American College of Medical Genetics and Genomics, in association with the American College of Obstetricians and Gynecologists, the Society for Maternal-Fetal Medicine, and the National Society of Genetic Counselors, have collaborated to provide education for clinicians and lab...
journal_title：Obstetrics and gynecology
pub_type： 社论,实务指引
doi：10.1097/AOG.0000000000000666
更新日期：2015-03-01 00:00:00
abstract：OBJECTIVE:To estimate detection rates for aneuploidy by first-trimester and sequential screening. METHODS:The study included women with singleton pregnancies who participated in the California Prenatal Screening Program with estimated delivery dates from August 2009 to December 2012 who had first- or first- and second...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000001040
更新日期：2015-10-01 00:00:00
abstract：:Diurnal variations in plasma unconjugated and total estriol were assessed in 11 third-trimester subjects with uncomplicated pregnancies. Commercially available 125I-labeled radioimmunoassay kits were used. Total plasma estriols reach a nadir during the hours of sleep (400 and 700 hours) which exceeds the episodic fluc...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1979-05-01 00:00:00
abstract：OBJECTIVE:To identify independent risk factors for endometrial neoplasia in women with abnormal perimenopausal or postmenopausal bleeding and to use those factors to develop and test a predictive model. METHODS:We conducted a case-control study of women with abnormal perimenopausal or postmenopausal bleeding who had e...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(98)00469-4
更新日期：1999-04-01 00:00:00
abstract：BACKGROUND:Screening of pregnant women for vaginal and rectal carriage of group B streptococci may also identify group A streptococcal carriers. The clinical significance of prenatal group A streptococcal carriage is unknown. CASES:Two women developed group A streptococcal puerperal sepsis after delivery at one hospit...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(01)01611-8
更新日期：2001-11-01 00:00:00
abstract：:Nine cases of condylomatous carcinoma (squamous cell carcinoma arising in condyloma acuminatum) of the vulva were studied for their clinical history, histopathology, and presence of human papillomavirus (HPV) DNA. Condylomatous carcinoma occurred primarily in an elderly population with a mean age of 70 years. There wa...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1988-07-01 00:00:00
abstract：OBJECTIVE:To investigate whether prepregnancy obesity is associated with adverse pregnancy outcomes among women without chronic disease. METHODS:Singleton deliveries (N=112,309) among mothers without chronic diseases in the Consortium on Safe Labor, a retrospective U.S. cohort, were analyzed using Poisson regression w...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000001465
更新日期：2016-07-01 00:00:00
abstract：OBJECTIVE:To use nationally representative data to produce prevalence estimates of combination estrogen-progestin therapy and estrogen-only therapy by covariates, and to evaluate differences between current use of short duration (less than 5 years) and current long-term use. METHODS:We analyzed data from female respon...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/j.obstetgynecol.2003.09.024
更新日期：2003-12-01 00:00:00
abstract：:Abortions by cervical dilatation with laminaria tents followed by placement of a metreurynter into the lower uterine cavity to provide a mechanical stretch (the method most often used in midterm abortions in Japan) was performed in 7 normal Japanese and American women, 19-24 weeks pregnant, to determine similarities ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1973-05-01 00:00:00
abstract：BACKGROUND:A rare complication of hysterectomy is the formation of a high-flow fistula between the uterine artery and uterine vein. Historically, these lesions were treated surgically. CASE:Two women with histories including hysterectomy presented with symptoms and physical examination signs suggestive of uterine arte...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e3181834660
更新日期：2009-02-01 00:00:00
abstract：:Deep venous thrombosis is a major complication following gynecologic surgery. Assessing a patient's risk of developing deep venous thrombosis is important for patient selection and in choosing appropriate prophylactic methods. Four hundred eleven patients undergoing major gynecologic surgery were evaluated prospective...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1987-02-01 00:00:00
abstract：:The purpose of the present retrospective study was to examine the relationship between hypertension and abruptio placentae. Two hundred sixty-five consecutive cases of abruption were reviewed, with an emphasis on the occurrence and severity of hypertensive disease. The results confirm a close relationship between abru...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1984-03-01 00:00:00
abstract：OBJECTIVE:To determine the association of intimate partner violence with maternal cigarette smoking before and during pregnancy. METHODS:Data were obtained for 196,391 U.S. mothers who delivered live neonates from 2004-2008 and completed the Pregnancy Risk Assessment Monitoring System survey 2-9 months postpartum. Int...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000000609
更新日期：2015-02-01 00:00:00
abstract：:Spontaneous preterm birth is a syndrome with many causes and thus unresponsive to a single intervention. It logically follows that patients with a prior spontaneous preterm birth are a heterogeneous group unlikely to respond equally to a single preventive intervention such as 17-α hydroxyprogesterone caproate. Further...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000001618
更新日期：2016-10-01 00:00:00
abstract：:Laparoscopic tubal sterilization, using a Silastic band to occlude the tubal lumen, was performed on 224 patients. The incidence of complications was low and only 2 pregnancies occurred. Further evaluation by hysterosalpingography on 97 patients revealed 2 distinct images. The site of tubal occlusion was seen on lapar...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1979-06-01 00:00:00
abstract：OBJECTIVE:To analyze the change in serial human chorionic gonadotropin (hCG) levels in women symptomatic with pain or bleeding who presented with nondiagnostic ultrasonography but were ultimately confirmed to have a viable intrauterine pregnancy. METHODS:The rise in serial hCG measures were modeled over time, with the...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000128174.48843.12
更新日期：2004-07-01 00:00:00
abstract：OBJECTIVE:To evaluate whether a second antenatal corticosteroid course is associated with an increased risk of neonatal sepsis after preterm premature rupture of membranes (PROM). METHODS:This secondary analysis is a cohort study with data from the Maternal-Fetal Medicine Units study on magnesium for neuroprotection. ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000000460
更新日期：2014-11-01 00:00:00
abstract：:Fetal movements (FM) were measured using a real-time B-scan method in 50 women in the third trimester. One hundred ninety-five observations were made. The number of FM per 20-minute observation period was similar in normal, diabetic, and hypertensive pregnancies and in patients with placenta previa, but was significan...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1979-12-01 00:00:00
abstract：:A prospective ultrasound study was conducted in 289 uncomplicated pregnancies with gestational ages ranging from 16-40 weeks. Biometric measurements obtained included biparietal diameter (BPD), head and abdominal circumferences, measurements of long bones, and maximal transverse colon diameter. The pattern of small in...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1987-11-01 00:00:00
abstract：:Sacral nerve stimulation delivers nonpainful electrical pulses to the sacral nerves that modulate the reflexes that control the bladder, bowels, and pelvic floor musculature. This relatively simple procedure was generated to improve and restore function in patients with a variety of pelvic floor disorders. Currently t...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1097/AOG.0000000000002968
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:Intravascular fetal transfusion is an important therapeutic advance but is associated with several complications. Regression of an umbilical artery associated with transfusion is rare. CASE:A case of red blood cell alloimmunization managed by serial transfusions was complicated by functional loss of an umbi...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(98)00502-x
更新日期：1999-05-01 00:00:00
abstract：OBJECTIVE:To estimate how implementation of the 2010 Affordable Care Act (ACA) might be associated with stage at diagnosis and time to treatment for women with ovarian cancer. METHODS:We conducted a retrospective cohort study using difference-in-differences analysis comparing stage at diagnosis and time to treatment b...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000003630
更新日期：2020-02-01 00:00:00
abstract：OBJECTIVE:To compare the effects of treatment with nicardipine and metoprolol in patients with hypertension during pregnancy. METHODS:One hundred pregnant patients with mild or moderate hypertension followed at the Centre Hospitalier Intercommunal de Créteil (France) were randomly allocated to treatment with either ni...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1994-09-01 00:00:00
