Nicardipine versus metoprolol in the treatment of hypertension during pregnancy: a randomized comparative trial.

Abstract:

OBJECTIVE:To compare the effects of treatment with nicardipine and metoprolol in patients with hypertension during pregnancy. METHODS:One hundred pregnant patients with mild or moderate hypertension followed at the Centre Hospitalier Intercommunal de Créteil (France) were randomly allocated to treatment with either nicardipine or metoprolol. Changes in maternal blood pressure (BP), laboratory indices, umbilical Doppler velocimetry, and neonatal outcome were compared by means of Student t test, chi 2 test, and analysis of variance. RESULTS:Nicardipine decreased maternal systolic and diastolic BP more than metoprolol (P < .001). Umbilical artery resistance was lower in nicardipine-treated patients (P < .001). Plasma uric acid and creatinine concentrations were increased less markedly in the nicardipine group (P < .05 and P < .01, respectively). The incidence of cesarean delivery for fetal distress was lower in the nicardipine group (P < .01). There was a trend toward higher birth weights in the nicardipine group but no significant difference in neonatal outcome. CONCLUSION:Nicardipine is more effective than metoprolol in decreasing maternal BP; neonatal outcome is not significantly different.

journal_name

Obstet Gynecol

authors

Jannet D,Carbonne B,Sebban E,Milliez J

subject

Has Abstract

pub_date

1994-09-01 00:00:00

pages

354-9

issue

3

eissn

0029-7844

issn

1873-233X

journal_volume

84

pub_type

临床试验,杂志文章,随机对照试验
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    abstract:OBJECTIVE:To evaluate the methodology of the cost-effectiveness and cost-benefit literature in obstetrics and gynecology. DATA SOURCES:We performed a MEDLINE search of the general and subspecialty obstetrics and gynecology journals for the years 1990 through 1996. METHODS OF STUDY SELECTION:Original investigations in...

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    doi:10.1016/s0029-7844(97)00679-0

    authors: Smith WJ,Blackmore CC

    更新日期:1998-03-01 00:00:00

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    abstract:OBJECTIVE:The effect of exogenous hormones on the incidence of breast cancer has been extensively studied. Most studies regarding hormonal contraception have focused on combined oral contraceptives, and there is paucity of literature regarding nonoral and progestin-only contraceptives. The present study analyzed the re...

    journal_title:Obstetrics and gynecology

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    doi:10.1097/01.AOG.0000178754.88912.b9

    authors: Backman T,Rauramo I,Jaakkola K,Inki P,Vaahtera K,Launonen A,Koskenvuo M

    更新日期:2005-10-01 00:00:00

  • Pulmonary edema following ritodrine-saline infusion in premature labor.

    abstract::Twenty-three patients with premature uterine contractions occurring between the 27th and 35th weeks of pregnancy were treated in a prospective and randomized study with intravenous ritodrine in a 0.1 wt/vol% solution of isotonic saline (N = 12) or isotonic glucose (N = 11). The aim of the study was to record the effec...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Philipsen T,Eriksen PS,Lynggård F

    更新日期:1981-09-01 00:00:00

  • Alternative Colposcopy Techniques: A Systematic Review and Meta-analysis.

    abstract:OBJECTIVE:To assess the diagnostic value of alternative (digital) colposcopy techniques for detection of cervical intraepithelial neoplasia (CIN) 2 or worse in a colposcopy population. DATA SOURCES:MEDLINE, EMBASE, ClinicalTrials.gov, and the Cochrane Library were searched from inception up to January 11, 2016, for st...

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    abstract:OBJECTIVE:To address the impact of simple antenatal educational interventions on breastfeeding practice. METHODS:A randomized controlled trial was carried out in a tertiary referral center from May 2002 to December 2004. A random sample of eligible low-risk antenatal patients was recruited from clinics in the National...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/01.AOG.0000249613.15466.26

    authors: Mattar CN,Chong YS,Chan YS,Chew A,Tan P,Chan YH,Rauff MH

    更新日期:2007-01-01 00:00:00

  • Maternal and neonatal outcomes of successful Kielland's rotational forceps delivery.

    abstract:OBJECTIVE:To estimate the rates of early neonatal and maternal complications in a consecutive series of successful Kielland's rotational forceps deliveries. METHODS:This was a retrospective cohort study of consecutive cases of successful rotational forceps deliveries performed in singleton pregnancies at 36 weeks of g...

    journal_title:Obstetrics and gynecology

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    authors: Stock SJ,Josephs K,Farquharson S,Love C,Cooper SE,Kissack C,Akolekar R,Norman JE,Denison FC

    更新日期:2013-05-01 00:00:00

  • Ultrastructural changes in endometriotic implants during the menstrual cycle.

    abstract::This report, the first ultrastructural study of endometriotic implants, compares the ectopic endometrium in 14 patients with that found in the uterus. The ultrastructural features of most of the glands of the ectopic endometrium resemble those of the corresponding glands lining the uterus. Specific ultrastructural cha...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Schweppe KW,Wynn RM

    更新日期:1981-10-01 00:00:00

  • Streptococcal toxic shock associated with septic abortion.

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Dotters DJ,Katz VL

    更新日期:1991-09-01 00:00:00

  • Fatal peritonitis following IUD-associated salpingitis.

    abstract::Previous reports have implicated the Dalkon shield intrauterine device (IUD) in septic second trimester abortion and maternal death from sepsis. In the case reported here, Fusobacterium necrophorum, a rarely pathogenic vaginal anaerobe, gained access to the uterus in a woman wearing a Dalkon shield and caused acute pa...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Maloy AL,Meier FA,Karl RC

    更新日期:1981-09-01 00:00:00

  • Primary cesarean section: factors related to postpartum infection.

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Ott WJ

    更新日期:1981-02-01 00:00:00

  • Malignant mixed müllerian tumor of the uterus arising in association with a viable gestation.

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Scioscia AL,Merino MJ,Haas M,Copel JA,Schwartz PE

    更新日期:1988-06-01 00:00:00

  • Neurodevelopmental Outcome After a Single Course of Antenatal Steroids in Children Born Preterm: A Systematic Review and Meta-analysis.

    abstract:OBJECTIVE:To systematically review and integrate data on the neurodevelopmental outcome of children after administration of a single course of antenatal corticosteroids for threatened preterm labor. DATA SOURCES:MEDLINE, Scopus, CENTRAL, and www.clinicaltrials.gov (inception to August 2014) using combinations of the t...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/AOG.0000000000000748

    authors: Sotiriadis A,Tsiami A,Papatheodorou S,Baschat AA,Sarafidis K,Makrydimas G

    更新日期:2015-06-01 00:00:00

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000000381

    authors: Nevadunsky NS,Van Arsdale A,Strickler HD,Moadel A,Kaur G,Levitt J,Girda E,Goldfinger M,Goldberg GL,Einstein MH

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Marrocco-Trischitta MM,Nicodemi EM,Nater C,Stillo F

    更新日期:2001-11-01 00:00:00

  • Diminished bilirubin binding by the serum of pregnant women.

    abstract::Enzymatic peroxidase oxidation was used to study albumin-bilirubin binding in the serum of pregnant women, their term infants, and nonpregnant women. When the bilirubin titration curves were corrected for differing albumin concentrations in the three groups, the bilirubin binding of pregnant women was inferior to that...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Ritter DA,Gabai BR,Kenny JD

    更新日期:1985-05-01 00:00:00

  • Association of Pharmacist Prescription of Hormonal Contraception With Unintended Pregnancies and Medicaid Costs.

    abstract:OBJECTIVE:To estimate unintended pregnancies averted and the cost effectiveness of pharmacist prescription of hormonal contraception. METHODS:A decision-analytic model was developed to determine the cost effectiveness of expanding the scope of pharmacists to prescribe hormonal contraception compared with the standard ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000003265

    authors: Rodriguez MI,Hersh A,Anderson LB,Hartung DM,Edelman AB

    更新日期:2019-06-01 00:00:00

  • Prolonged Detection of Zika Virus RNA in Pregnant Women.

    abstract:OBJECTIVE:Zika virus infection during pregnancy is a cause of microcephaly and other fetal brain abnormalities. Reports indicate that the duration of detectable viral RNA in serum after symptom onset is brief. In a recent case report involving a severely affected fetus, Zika virus RNA was detected in maternal serum 10 ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000001625

    authors: Meaney-Delman D,Oduyebo T,Polen KND,White JL,Bingham AM,Slavinski SA,Heberlein-Larson L,St George K,Rakeman JL,Hills S,Olson CK,Adamski A,Culver Barlow L,Lee EH,Likos AM,Muñoz JL,Petersen EE,Dufort EM,Dean AB,Cortes

    更新日期:2016-10-01 00:00:00

  • DNA content as a prognostic factor in endometrial carcinoma.

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    journal_title:Obstetrics and gynecology

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    doi:

    authors: Newbury R,Schuerch C,Goodspeed N,Fanning J,Glidewell O,Evans M

    更新日期:1990-08-01 00:00:00

  • Radiation risks in pregnancy.

    abstract::A major contraindication of radiodiagnostic procedures is pregnancy. Approximately 1% of all pregnant women are given abdominal x-rays during the first trimester of pregnancy. Evaluation of radiation exposure should involve consideration of the types of examinations performed and when performed, as well as radiation d...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:

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    更新日期:1982-08-01 00:00:00

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    pub_type: 杂志文章

    doi:

    authors: Gimovsky ML,Petrie RH,Todd WD

    更新日期:1980-12-01 00:00:00

  • Posttraumatic stress disorder and pregnancy complications.

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(00)01097-8

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    更新日期:2001-01-01 00:00:00

  • Diagnosis of placental abscess in association with recurrent maternal bacteremia in a twin pregnancy.

    abstract:BACKGROUND:Placental abscess formation is rarely recognized prenatally. We present a case detected ultrasonographically that developed from a central line infection and caused recurrent maternal bacteremia. CASE:A young woman with a 21-week twin gestation presented with recurrent fevers. She had received treatment for...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000165268.09352.ed

    authors: Meirowitz NB,Fleischer A,Powers M,Hippolyte F

    更新日期:2006-02-01 00:00:00

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    journal_title:Obstetrics and gynecology

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    doi:

    authors: Catalano PM,Roman NM,Tyzbir ED,Merritt AO,Driscoll P,Amini SB

    更新日期:1993-04-01 00:00:00

  • Immunologic detection of condylomata acuminata-specific antigens.

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Dunn J,Weinstein L,Droegemueller W,Meinke W

    更新日期:1981-03-01 00:00:00

  • Umbilical artery aneurysm: prenatal diagnosis and management.

    abstract:BACKGROUND:An umbilical artery aneurysm is an extremely rare lesion. The purpose of this report is to describe the prenatal sonographic characteristics of such a lesion and potential obstetric complications. CASE:A 26-year-old woman, gravida 2, para 1, at 30 weeks' gestation was referred for an ultrasound examination ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Siddiqi TA,Bendon R,Schultz DM,Miodovnik M

    更新日期:1992-09-01 00:00:00

  • Plasma Concentrations of Tranexamic Acid in Postpartum Women After Oral Administration.

    abstract:OBJECTIVE:To evaluate the pharmacokinetics of tranexamic acid after oral administration to postpartum women. METHODS:We conducted a single-center pharmacokinetic study at Teaching Hospital-Jaffna, Sri Lanka, on 12 healthy postpartum women who delivered vaginally. After oral administration of 2 g of immediate-release t...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:10.1097/AOG.0000000000003750

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    更新日期:2020-04-01 00:00:00

  • The effects of nonsteroidal antiinflammatory compounds on fetal circulation and pulmonary function.

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    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Rudolph AM

    更新日期:1981-11-01 00:00:00

  • ACOG Committee Opinion #295: pain relief during labor.

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    journal_title:Obstetrics and gynecology

    pub_type: 指南,杂志文章,实务指引

    doi:

    authors:

    更新日期:2004-07-01 00:00:00

  • The relationship of one abnormal glucose tolerance test value and pregnancy complications.

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    doi:

    authors: Lindsay MK,Graves W,Klein L

    更新日期:1989-01-01 00:00:00

  • Occult Uterine Sarcoma and Leiomyosarcoma: Incidence of and Survival Associated With Morcellation.

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