Abstract:
:Rats, trained to discriminate 1.5 mg/kg of the hallucinogenic agent 5-methoxy-N,N-dimethyltryptamine (5-OMe DMT) from saline in a two-lever drug discrimination task, were challenged with various doses of the 4-methoxy, 4-methylthio and 5-methylthio derivatives of DMT. The 5-OMe DMT cue was found to generalize to all three of these agents; the order of potency is 5-OMe greater than 5-SMe greater than 4-OMe greater than 4-SMe DMT.
journal_name
Life Scijournal_title
Life sciencesauthors
Glennon RA,Young R,Benington F,Morin RDdoi
10.1016/0024-3205(82)90463-5subject
Has Abstractpub_date
1982-02-01 00:00:00pages
465-7issue
5eissn
0024-3205issn
1879-0631pii
0024-3205(82)90463-5journal_volume
30pub_type
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