Fetal contribution to oxytocin in human labor.

Abstract:

:Fetal oxytocin contribution to the mother during spontaneous labor was investigated using a specific and sensitive radioimmunoassay to measure oxytocin in blood, amniotic fluid, and urine. In 26 subjects with spontaneous labor and vaginal delivery (Group I) and 18 subjects with cesarean section after labor (Group II), umbilical arterial plasma (UA) oxytocin concentrations were significantly higher than umbilical venous plasma (UV) ocytocin concentrations. With elective cesarean section (Group III), UA oxytocin concentration was 29.8 +/- 7.5 pg/ml and UV oxytocin concentration was 16.1 +/- 5.9 pg/ml (n = 14). In contrast, the mean UV oxytocin concentration was higher than the mean UA oxytocin concentration, when oxytocin was given to the mothen concentration in Groups I and II was significantly higher than in Group III. Amniotic fluid oxytocin concentrations in Group I and II patients were higher than in Group III. Oxytocin was also present in fetal urine. The findings indicate that during spontaneous labor, oxytocin is produced by the fetus and flows toward the maternal circulation.

journal_name

Obstet Gynecol

authors

Dawood MY,Wang CF,Gupta R,Fuchs F

subject

Has Abstract

pub_date

1978-08-01 00:00:00

pages

205-9

issue

2

eissn

0029-7844

issn

1873-233X

journal_volume

52

pub_type

杂志文章
  • Risk factors for adult paternity in births to adolescents.

    abstract:OBJECTIVE:To examine the risk factors for adult (aged 20 years and older) paternity in births to teenagers (14-17 years of age). METHODS:This was a population-based, retrospective cohort analysis of 27,215 adolescent mothers residing in California who had a live singleton birth during 1993. Adjusted risks for adult pa...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/S0029-7844(96)00481-4

    authors: Taylor D,Chavez G,Chabra A,Boggess J

    更新日期:1997-02-01 00:00:00

  • Doppler assessment of the intervillous blood flow in normal and abnormal early pregnancy.

    abstract:OBJECTIVE:To compare resistance index (RI) and pulsatility index (PI) in the spiral and intervillous arteries, and peak systolic velocity of the continuous intervillous flow in normal and abnormal first-trimester pregnancy. METHODS:Transvaginal color and pulsed Doppler were used in a prospective analysis of 60 normal ...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:10.1016/S0029-7844(96)00422-X

    authors: Kurjak A,Kupesic S

    更新日期:1997-02-01 00:00:00

  • Porencephaly secondary to fetal trauma during amniocentesis.

    abstract:BACKGROUND:There has been one reported case of porencephaly diagnosed postnatally as a result of amniocentesis. We report the first antenatal diagnosis of porencephaly, which apparently resulted from penetration of the fetal skull during amniocentesis. CASE:A 37-year-old woman had genetic amniocentesis at 16 weeks' ge...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0029-7844(94)00315-5

    authors: Eller KM,Kuller JA

    更新日期:1995-05-01 00:00:00

  • Effect of nicotine on human fetal blood flow.

    abstract::Immediate maternal and fetal cardiovascular responses to different doses of nicotine and carbon monoxide were studied in 24 pregnant smokers. A noninvasive pulsed Doppler ultrasound technique was used for measuring fetal blood flow in the descending thoracic aorta, the intra-abdominal part of the umbilical vein, and i...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:

    authors: Lindblad A,Marsál K,Andersson KE

    更新日期:1988-09-01 00:00:00

  • Efficacy, safety, and tolerability of a monophasic oral contraceptive containing nomegestrol acetate and 17β-estradiol: a randomized controlled trial.

    abstract:OBJECTIVE:To estimate the efficacy, cycle control, tolerability, and safety of a monophasic combined oral contraceptive containing nomegestrol acetate and 17β-estradiol (E2) in comparison with drospirenone and ethinyl E2. METHODS:In a randomized, open-label, comparative multicenter trial, healthy women (n=2,281; age 1...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/AOG.0b013e318250c3a0

    authors: Westhoff C,Kaunitz AM,Korver T,Sommer W,Bahamondes L,Darney P,Verhoeven C

    更新日期:2012-05-01 00:00:00

  • Committee Opinion No 705 Summary: Mental Health Disorders In Adolescents.

    abstract::Mental health disorders in adolescence are a significant problem, relatively common, and amenable to treatment or intervention. Obstetrician-gynecologists who see adolescent patients are highly likely to see adolescents and young women who have one or more mental health disorders. Some of these disorders may interfere...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,实务指引

    doi:10.1097/AOG.0000000000002153

    authors:

    更新日期:2017-07-01 00:00:00

  • Committee opinion no 611: method for estimating due date.

    abstract::: Accurate dating of pregnancy is important to improve outcomes and is a research and public health imperative. As soon as data from the last menstrual period, the first accurate ultrasound examination, or both are obtained, the gestational age and the estimated due date should be determined, discussed with the patien...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/01.AOG.0000454932.15177.be

    authors:

    更新日期:2014-10-01 00:00:00

  • Short-term effects of tamoxifen, medroxyprogesterone acetate, and their combination on receptor kinetics and 17 beta-hydroxysteroid dehydrogenase in human endometrium.

    abstract::The interactions of an antiestrogen (tamoxifen) and a progestin (medroxyprogesterone acetate) on endometrial 17 beta-hydroxysteroid dehydrogenase activities were studied in short-term experiments (four to 96 hours) in normally menstruating women at the follicular phase and were related to simultaneously measured conce...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Neumannová M,Kauppila A,Kivinen S,Vihko R

    更新日期:1985-11-01 00:00:00

  • Thrombocytopenia in two patients treated with low-dose heparin.

    abstract::Two cases of thrombocytopenia, one resulting in bleeding, are reported in patients treated with prophylactic low-dose heparin. The evidence indicates that low-dose heparin was responsible. A review of the literature indicates that heparin-induced thrombocytopenia may be a common event. Since low-dose heparin has been ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Galle PC,Muss HB,McGrath KM,Stuart JJ,Homesley HD

    更新日期:1978-07-01 00:00:00

  • Genital herpes during pregnancy: inability to distinguish primary and recurrent infections clinically.

    abstract:OBJECTIVE:To determine if the signs and symptoms of genital herpes in pregnancy accurately identify primary genital herpes infections using serologic testing for final classification. METHODS:Twenty-three women with clinical signs and symptoms suggestive of primary genital herpes infections in the second and third tri...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(97)00121-x

    authors: Hensleigh PA,Andrews WW,Brown Z,Greenspoon J,Yasukawa L,Prober CG

    更新日期:1997-06-01 00:00:00

  • Immunomodulation in women with endometriosis receiving GnRH agonist.

    abstract:OBJECTIVE:To assess the changes in the subpopulations of lymphocytes and in lymphocyte mitogenic activity in women with endometriosis receiving GnRH-agonist treatment. METHODS:Twenty-six women with advanced endometriosis from the National Cheng Kung University Medical College were studied. Each received a total of six...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0029-7844(97)00145-2

    authors: Hsu CC,Lin YS,Wang ST,Huang KE

    更新日期:1997-06-01 00:00:00

  • Preoperative vaginal preparation with povidone-iodine and the risk of postcesarean endometritis.

    abstract:OBJECTIVE:Postcesarean endometritis and wound infection remain significant morbidities, despite use of strategies to prevent these complications. We investigated the effect of preoperative vaginal preparation with povidone-iodine as a preventive intervention against postcesarean endometritis and wound infection. METHO...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1097/01.AOG.0000164032.16599.7e

    authors: Starr RV,Zurawski J,Ismail M

    更新日期:2005-05-01 00:00:00

  • S.O.S! I'm short of breath!

    abstract:BACKGROUND:There are various causes of shortness of breath in a young, pregnant woman. The importance of entertaining a broad differential diagnosis is highlighted in this case. CASE:A young, pregnant African-American woman presented in her third trimester with acute onset of shortness of breath. A team approach by di...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000267318.56856.2a

    authors: Uppalapati R

    更新日期:2007-06-01 00:00:00

  • Long-term effect of tubal sterilization on menstrual indices and pelvic pain.

    abstract:OBJECTIVE:To evaluate the long-term effect of tubal sterilization on menstrual indices and pelvic pain. METHODS:Five hundred women undergoing sterilization were interviewed before sterilization, 6-10 months after surgery, and 3-4.5 years later. Four hundred sixty-six non-sterilized comparison women were interviewed in...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Rulin MC,Davidson AR,Philliber SG,Graves WL,Cushman LF

    更新日期:1993-07-01 00:00:00

  • What is new in exercise in pregnancy? Best articles from the past year.

    abstract::This month we focus on current research in exercise in pregnancy. Dr. Blanchette discusses four recent publications, and each is concluded with a "bottom line" that is the take-home message. The complete reference for each can be found in on this page, along with direct links to the abstracts. ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000000658

    authors: Blanchette HA

    更新日期:2015-02-01 00:00:00

  • The genetics of intersexuality: clinical and theoretic perspectives.

    abstract::Recent studies using newly devised serologic techniques have dramatically advanced our understanding of gonadal organogenesis and aberrant sexual differentiation. Thus XY gonadal dysgenesis, XX male syndrome, and XX true hermaphroditism, for example, may be seen as typifying specific errors of regulation, synthesis, o...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:

    authors: Wachtel SS

    更新日期:1979-12-01 00:00:00

  • Use of a novel visual aid to improve estimation of obstetric blood loss.

    abstract:OBJECTIVE:Visual estimation of blood loss is often inaccurate and imprecise. Obstetric bleeding requires expedient identification and intervention to prevent maternal morbidity and mortality. We aimed to create a visual aid to improve accuracy of estimated obstetric blood loss. METHODS:We designed a pocket card contai...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:10.1097/AOG.0000000000000233

    authors: Zuckerwise LC,Pettker CM,Illuzzi J,Raab CR,Lipkind HS

    更新日期:2014-05-01 00:00:00

  • Use of recombinant activated factor VII in primary postpartum hemorrhage: the Northern European registry 2000-2004.

    abstract:OBJECTIVE:To collect data from nine European countries for cases of obstetric hemorrhage between 2000 and 2004 in which recombinant activated factor VII (rFVIIa) was used. METHODS:The cases were identified through national surveys. Standardized case report forms included sociodemographic details, past medical and obst...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000288515.48066.99

    authors: Alfirevic Z,Elbourne D,Pavord S,Bolte A,Van Geijn H,Mercier F,Ahonen J,Bremme K,Bødker B,Magnúsdóttir EM,Salvesen K,Prendiville W,Truesdale A,Clemens F,Piercy D,Gyte G

    更新日期:2007-12-01 00:00:00

  • What Is New in Maternal Heart Disease?: Best Articles From the Past Year.

    abstract::This month we focus on current research in maternal heart disease. Dr. Metz discusses four recent publications, which are concluded with a "bottom-line" that is the take-home message. A complete reference for each can be found on on this page along with direct links to abstracts. ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000003037

    authors: Metz TD

    更新日期:2019-01-01 00:00:00

  • Communicating septate uterus with double cervix: a rare malformation.

    abstract::The class of uterine malformations known as communicating uteri is characterized by two separate uterocervical cavities connected by an isthmic communication. Nine types have been described. We report the second proven case of a septate communicating uterus with double cervix. Investigation of secondary infertility in...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Lev-Toaff AS,Kim SS,Toaff ME

    更新日期:1992-05-01 00:00:00

  • Maternal tryptophan and kynurenine pathway metabolites and risk of preeclampsia.

    abstract:OBJECTIVE:To estimate the association of maternal plasma concentrations of tryptophan and six kynurenine pathway metabolites with the risk of preeclampsia. METHODS:The study was based on a subsample of 2,936 pregnant women who delivered singleton neonates in the Norwegian Mother and Child Cohort Study in 2002-2003. Ma...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e318255004e

    authors: Nilsen RM,Bjørke-Monsen AL,Midttun O,Nygård O,Pedersen ER,Ulvik A,Magnus P,Gjessing HK,Vollset SE,Ueland PM

    更新日期:2012-06-01 00:00:00

  • Adnexal masses in pregnancy: surgery compared with observation.

    abstract:OBJECTIVE:To estimate whether the delay of surgery impacts the risk of adverse maternal and fetal outcomes in patients diagnosed with an adnexal mass during pregnancy. METHODS:A review was performed of pregnant patients diagnosed with an adnexal mass 5 cm or greater in diameter. Data collected included age, gravity/pa...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000157465.99639.e5

    authors: Schmeler KM,Mayo-Smith WW,Peipert JF,Weitzen S,Manuel MD,Gordinier ME

    更新日期:2005-05-01 00:00:00

  • Interpreting the literature in obstetrics and gynecology: II. Logistic regression and related issues.

    abstract::The goal of epidemiology is accurate measure of the relationship between an exposure and a disease of interest. The control of covariates of the exposure-disease relationship is required to obtain a valid measure. Two types of covariates, confounders and effect modifiers, must be considered. Investigators can design s...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:

    authors: Peterson HB,Kleinbaum DG

    更新日期:1991-10-01 00:00:00

  • A randomized, double-blind, placebo-controlled, cross-over trial to assess the side effects of medroxyprogesterone acetate in hormone replacement therapy.

    abstract::Cyclic progestin therapy has been widely advocated as an adjunct to postmenopausal estrogen replacement therapy to reduce the risk of endometrial carcinoma. Acceptance of this approach, however, appears to have preceded detailed evaluation of possible adverse side effects of progestins that could result in patient non...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Kirkham C,Hahn PM,Van Vugt DA,Carmichael JA,Reid RL

    更新日期:1991-07-01 00:00:00

  • Increased live birth rate in twin pregnancies resulting from embryo assistance.

    abstract:OBJECTIVE:To estimate why the live birth rate per implanted embryo is higher in twin than in singleton pregnancies. METHODS:Data from 1,159 singleton and 523 dichorionic twin pregnancies, obtained after assisted conception, were included. To account for the higher live birth rate observed in twin pregnancies, two poss...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e31823bf978

    authors: Miró F,Vidal E,Balasch J

    更新日期:2012-01-01 00:00:00

  • Effect of vaginal lubricants on natural fertility.

    abstract:OBJECTIVE:Over-the-counter vaginal lubricants have been shown to negatively affect in vitro sperm motility. The objective of this study was to estimate the effect of vaginal lubricant use during procreative intercourse on natural fertility. METHODS:Women aged 30-44 years with no history of infertility who had been try...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e31825b87ae

    authors: Steiner AZ,Long DL,Tanner C,Herring AH

    更新日期:2012-07-01 00:00:00

  • Maternal hemodynamics and impaired fetal growth in pregnancy-induced hypertension.

    abstract::Twenty-one subjects with pregnancy-induced hypertension were investigated with regard to the relationship between maternal hemodynamics and fetal growth. Five of the infants were small for gestational age (SGA) (less than tenth percentile) and 16 were appropriate for gestational age (AGA) (greater than tenth percentil...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Nisell H,Lunell NO,Linde B

    更新日期:1988-02-01 00:00:00

  • Uterine sarcoidosis potentially associated with interferon-alpha use for chronic hepatitis C infection.

    abstract:BACKGROUND:A regimen including interferon-alpha has become the standard of care in the treatment of chronic hepatitis C over the last decade. One rare adverse effect associated with the use of interferon-alpha is a granulomatous pulmonary reaction. CASE:A unique case of uterine sarcoidosis associated with the use of i...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000157764.44292.aa

    authors: Tsiodras S,Drimala P,Stavreas N,Dachlythras M,Alamani AM,Naoum G

    更新日期:2005-05-01 00:00:00

  • Maternal and neonatal outcomes of successful Kielland's rotational forceps delivery.

    abstract:OBJECTIVE:To estimate the rates of early neonatal and maternal complications in a consecutive series of successful Kielland's rotational forceps deliveries. METHODS:This was a retrospective cohort study of consecutive cases of successful rotational forceps deliveries performed in singleton pregnancies at 36 weeks of g...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e31828b72cb

    authors: Stock SJ,Josephs K,Farquharson S,Love C,Cooper SE,Kissack C,Akolekar R,Norman JE,Denison FC

    更新日期:2013-05-01 00:00:00

  • Endometriosis of the bowel.

    abstract::One hundred sixty-three cases of endometriosis of the bowel (5.4% of 3037 laparotomies for endometriosis at the Ochsner Foundation Hospital) were reviewed to assess the management of this complication. Colon and rectal surgeons performed bowel resections of the colon in 30 cases and resections of the ileum and/or cecu...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Weed JC,Ray JE

    更新日期:1987-05-01 00:00:00