Effect of nicotine on human fetal blood flow.

Abstract:

:Immediate maternal and fetal cardiovascular responses to different doses of nicotine and carbon monoxide were studied in 24 pregnant smokers. A noninvasive pulsed Doppler ultrasound technique was used for measuring fetal blood flow in the descending thoracic aorta, the intra-abdominal part of the umbilical vein, and in the umbilical artery. Maternal plasma concentrations of nicotine, carbon monoxide, and catecholamines were measured. Maternal heart rate, blood pressure, fetal heart rate, and fetal aortic and umbilical vein blood flow increased, while pulsatility indices of the fetal aortic and umbilical artery blood velocity waveforms decreased, with increasing maternal nicotine levels; all were unaffected by carbon monoxide. Catecholamine levels remained unaffected. These results seem to confirm that the maternal nicotine intake due to smoking has an immediate, dose-dependent effect on fetal blood flow.

journal_name

Obstet Gynecol

authors

Lindblad A,Marsál K,Andersson KE

subject

Has Abstract

pub_date

1988-09-01 00:00:00

pages

371-82

issue

3 Pt 1

eissn

0029-7844

issn

1873-233X

journal_volume

72

pub_type

临床试验,杂志文章
  • Lymphatic spread in stage Ib and II cervical carcinoma: anatomy and surgical implications.

    abstract:OBJECTIVE:To determine the frequency and topography of pelvic and para-aortic node involvement in cervical carcinoma and to identify the appropriate level for resection of the lymphatic chains. METHODS:Between 1985 and 1994, 421 women with stage Ib or II cervical carcinoma were treated by surgery in combination with i...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(97)00696-0

    authors: Michel G,Morice P,Castaigne D,Leblanc M,Rey A,Duvillard P

    更新日期:1998-03-01 00:00:00

  • ACOG Practice Bulletin Number 131: Screening for cervical cancer.

    abstract::The incidence of cervical cancer in the United States has decreased more than 50% in the past 30 years because of widespread screening with cervical cytology. In 1975, the rate was 14.8 per 100,000 women. By 2008, it had been reduced to 6.6 per 100,000 women. Mortality from the disease has undergone a similar decrease...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,实务指引

    doi:10.1097/aog.0b013e318277c92a

    authors: Committee on Practice Bulletins—Gynecology.

    更新日期:2012-11-01 00:00:00

  • Elective cesarean delivery, neonatal intensive care unit admission, and neonatal respiratory distress.

    abstract:OBJECTIVE:To evaluate the relationship among gestational age at elective cesarean delivery, neonatal intensive care unit (NICU) admission, and whether the presence of pre-cesarean delivery labor or ruptured membranes affected the incidence of neonatal respiratory distress. METHODS:A chart review was performed of all e...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e31816736e7

    authors: Yee W,Amin H,Wood S

    更新日期:2008-04-01 00:00:00

  • Social factors affecting treatment of cervical cancer: ethical issues and policy implications.

    abstract::Health care in the United States has become a privilege rather than a right. Patients who have the greatest need are the ones most likely to be denied this privilege. Despite recent advances in disease detection and treatment, many patients do not receive even the bare minimum of care. The high complexity of the healt...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e318165f1a9

    authors: Westin SN,Bustillos D,Gano JB,Fields MM,Coker AL,Sun CC,Ramondetta LM

    更新日期:2008-03-01 00:00:00

  • Interbirth interval with frequency of cesarean delivery.

    abstract:OBJECTIVE:To estimate whether and to what extent interbirth interval is associated with cesarean delivery. METHODS:This is a retrospective cohort study of 2,528 multiparous women who presented to labor and delivery at a single tertiary care obstetric hospital during an 18-month period. Women were grouped by their inte...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e31821c4368

    authors: Miller ES,Grobman WA

    更新日期:2011-07-01 00:00:00

  • ACOG Committee Opinion No. 755 Summary: Well-Woman Visit.

    abstract::A well-woman visit provides an excellent opportunity to counsel patients about maintaining a healthy lifestyle and minimizing health risks. Given the shifting and complex landscape of care, in which many women may not receive all the recommended preventive services, obstetrician-gynecologists have an opportunity to co...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000002898

    authors:

    更新日期:2018-10-01 00:00:00

  • Postpartum Blood Loss in Women Treated for Intrahepatic Cholestasis of Pregnancy.

    abstract:OBJECTIVE:To evaluate postpartum blood loss in women with treated intrahepatic cholestasis of pregnancy. METHODS:In a retrospective case-control study, 15,083 deliveries including 348 women with intrahepatic cholestasis of pregnancy (2.3%) were analyzed from 2004 to 2014. To adjust for differences in baseline characte...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000001693

    authors: Furrer R,Winter K,Schäffer L,Zimmermann R,Burkhardt T,Haslinger C

    更新日期:2016-11-01 00:00:00

  • Doppler umbilical artery studies in the twin-twin transfusion syndrome.

    abstract::Eleven patients with twin pregnancies were identified as having twin-twin transfusion syndrome on the basis of like-sex twins with monochorionic placentation and umbilical venous blood hemoglobin differences exceeding 50 g/L at delivery. Umbilical artery velocity-time waveform studies had been performed in these pregn...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Giles WB,Trudinger BJ,Cook CM,Connelly AJ

    更新日期:1990-12-01 00:00:00

  • Amniotic fluid cortisol as an index of fetal lung maturity.

    abstract::Amniotic fluid cortisol concentration was compared with lecithin/sphingomyelin ratio, gestational age, and eventual birth-weight in a large series of normal and high-risk human pregnancies in an effort to determine whether cortisol could be used as a reliable indicator of fetal maturity. It appears that when used alon...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Gewolb IH,Hobbins JC,Tan SY

    更新日期:1977-04-01 00:00:00

  • Fetal cerebral Doppler studies as a predictor of perinatal outcome and subsequent neurologic handicap.

    abstract:OBJECTIVE:To study the use of middle cerebral arterial Doppler findings in a group of high-risk fetuses as a predictor of adverse perinatal outcome, including subsequent neurologic handicap. METHODS:A group of very high-risk fetuses was recruited over a 2-year period for study. Weekly fetal biometries and Doppler stud...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/0029-7844(96)00062-2

    authors: Chan FY,Pun TC,Lam P,Lam C,Lee CP,Lam YH

    更新日期:1996-06-01 00:00:00

  • State Medicaid Coverage of Medically Necessary Abortions and Severe Maternal Morbidity and Maternal Mortality.

    abstract:OBJECTIVE:To estimate the association between state Medicaid coverage of medically necessary abortion and severe maternal morbidity and in-hospital maternal mortality in the United States. METHODS:We used data on pregnancy-related hospitalizations from the Nationwide Inpatient Sample from 2000 to 2011 (weighted n=38,0...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000001982

    authors: Jarlenski M,Hutcheon JA,Bodnar LM,Simhan HN

    更新日期:2017-05-01 00:00:00

  • Indomethacin and antibiotics in examination-indicated cerclage: a randomized controlled trial.

    abstract:OBJECTIVE:To evaluate whether perioperative indomethacin and antibiotic administration at the time of examination-indicated cerclage placement prolongs gestation. METHODS:This is a randomized controlled trial performed at a single tertiary care hospital between March 2010 and November 2012. Women older than 18 years o...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/AOG.0000000000000228

    authors: Miller ES,Grobman WA,Fonseca L,Robinson BK

    更新日期:2014-06-01 00:00:00

  • Fetal activity acceleration determination for the evaluation of fetal reserve.

    abstract::Fetal activity acceleration determination (FAD) was performed 462 times on a total of 410 patients for the evaluation of fetal reserve. Simultaneous oxytocin challenge test (OCT) was performed 324 times to evaluate the correlation between the two tests. In 308 instances, FAD was positive and OCT was either negative or...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Lee CY,Di Loreto PC,Logrand B

    更新日期:1976-07-01 00:00:00

  • Chorioamnionitis and sternoclavicular septic arthritis after drainage of Bartholin gland abscess.

    abstract:BACKGROUND:Complications after drainage of Bartholin gland abscesses in pregnancy are rare. CASE:A 29-year-old primigravid at 35 weeks of gestation with dichorionic-diamniotic twins underwent Bartholin gland abscess drainage. Afterward, she reported shoulder pain and became febrile. Examination revealed maternal and f...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000000284

    authors: Kelly JC,Jia X,Vindenes T,Urato AC

    更新日期:2014-08-01 00:00:00

  • Effect of birth order on intraventricular hemorrhage in very low birth weight twins.

    abstract::We evaluated the effect of birth order on the incidence and severity of intraventricular hemorrhage in 29 sets of very low birth weight twins (1500 g or less). Intraventricular hemorrhage occurred in 55% of first-presenting twins and 62% of second-presenting twins. The incidence of minor intraventricular hemorrhage (g...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Pearlman SA,Batton DG

    更新日期:1988-03-01 00:00:00

  • Bleeding pattern and endometrial changes during continuous combined hormone replacement therapy. The Ogen/Provera Study Group.

    abstract:OBJECTIVE:To establish the optimum oral daily dose of micronized medroxyprogesterone acetate, given in combination with a fixed oral dose of estrone (E1) sulfate as hormone replacement therapy, that provides endometrial protection and induces cessation of vaginal bleeding. METHODS:This multicenter, randomized, double-...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0029-7844(98)00038-6

    authors: Nand SL,Webster MA,Baber R,O'Connor V

    更新日期:1998-05-01 00:00:00

  • Efficacy of maternal and neonatal chemoprophylaxis for early-onset group B streptococcal disease.

    abstract:OBJECTIVE:To estimate the rate of early-onset group B streptococcal (GBS) neonatal sepsis with combined maternal and neonatal chemoprophylaxis. METHODS:Since 1995, GBS chemoprophylaxis at our institution has consisted of intrapartum antibiotic prophylaxis to all women with identified risk factors. In addition, a singl...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e3182592451

    authors: Stafford IA,Stewart RD,Sheffield JS,Wendel GD Jr,Sanchez PJ,McIntire DD,Roberts SW

    更新日期:2012-07-01 00:00:00

  • Effectiveness of intrapartum antibiotic prophylaxis for prevention of early-onset group B streptococcal disease.

    abstract:OBJECTIVE:To estimate the effectiveness against early-onset group B streptococcal (GBS) disease of intrapartum antibiotic prophylaxis among term and preterm deliveries, deliveries with fewer than 4 hours of antibiotics, and deliveries receiving clindamycin regimens. METHODS:We performed a secondary analysis of the Bir...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e318280d4f6

    authors: Fairlie T,Zell ER,Schrag S

    更新日期:2013-03-01 00:00:00

  • Androgenic response in anovulatory women during menotropins stimulation.

    abstract::Menotropins (human menopausal gonadotropin [hMG]) are used to induce follicular maturation and ovulation in anovulatory infertile women. To determine how hMG stimulation affected ovarian androgen production during such therapy, plasma androstenedione (A) and testosterone (T) levels were measured at the beginning and e...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Skaf RA,Shelden R,Kemmann E

    更新日期:1981-12-01 00:00:00

  • Antenatal Corticosteroid Therapy Before 24 Weeks of Gestation: A Systematic Review and Meta-analysis.

    abstract:OBJECTIVE:To evaluate the effectiveness of antenatal corticosteroids compared with placebo or no treatment in neonates born before 24 weeks of gestation. DATA SOURCES:We searched MEDLINE, EMBASE, Cumulative Index to Nursing and Allied Health Literature (CINAHL), and Cochrane Central Register of Controlled Trials datab...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/AOG.0000000000001355

    authors: Park CK,Isayama T,McDonald SD

    更新日期:2016-04-01 00:00:00

  • Variation in ovarian conservation in women undergoing hysterectomy for benign indications.

    abstract:OBJECTIVE:Emerging data suggest that oophorectomy at the time of hysterectomy for benign indications may increase long-term morbidity and mortality. We performed a population-based analysis to estimate the rates of oophorectomy in women undergoing hysterectomy for benign indications. METHODS:The Perspective database w...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0b013e3182887a47

    authors: Perera HK,Ananth CV,Richards CA,Neugut AI,Lewin SN,Lu YS,Herzog TJ,Hershman DL,Wright JD

    更新日期:2013-04-01 00:00:00

  • Cesarean delivery and the long-term risk of offspring obesity.

    abstract:OBJECTIVE:To examine the association between the mode of delivery and the risk of offspring obesity by age 21 years using a large community-based birth cohort study in Australia. METHODS:We followed-up a subsample of 2,625 offspring for whom we had measured physical assessments, including height and weight at 21 years...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000000016

    authors: Mamun AA,Sutharsan R,O'Callaghan M,Williams G,Najman J,McIntyre HD,Callaway L

    更新日期:2013-12-01 00:00:00

  • Relationship of ultrasound findings after cesarean section to operative morbidity.

    abstract::Postcesarean section febrile morbidity remains a common problem on obstetric services. Although a few preliminary studies have reported on the use of ultrasound to assess the postcesarean section patient, they have not compared sonographic findings with either intraoperative or postoperative events. These reports have...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Faustin D,Minkoff H,Schaffer R,Crombleholme W,Schwarz R

    更新日期:1985-08-01 00:00:00

  • Mesenteric supernumerary ovary.

    abstract::Following is a report and a review of literature concerning the supernumerary ovary. Up to now only 7 cases have been reported, and our case appears to be the eighth. The anatomic situation in this case was unusual since it was found in the mesentery. Of the cases previously reported, 2 have been associated with benig...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Abrego D,Ibrahim AA

    更新日期:1975-03-01 00:00:00

  • Neurodevelopmental Outcome After a Single Course of Antenatal Steroids in Children Born Preterm: A Systematic Review and Meta-analysis.

    abstract:OBJECTIVE:To systematically review and integrate data on the neurodevelopmental outcome of children after administration of a single course of antenatal corticosteroids for threatened preterm labor. DATA SOURCES:MEDLINE, Scopus, CENTRAL, and www.clinicaltrials.gov (inception to August 2014) using combinations of the t...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,meta分析,评审

    doi:10.1097/AOG.0000000000000748

    authors: Sotiriadis A,Tsiami A,Papatheodorou S,Baschat AA,Sarafidis K,Makrydimas G

    更新日期:2015-06-01 00:00:00

  • Postural changes can reduce leakage in women with stress urinary incontinence.

    abstract:OBJECTIVE:To assess the efficacy of postural changes, such as crossing the legs, in reducing urine leakage in women with stress urinary incontinence. METHODS:Sixty-five women with urodynamically proven stress incontinence underwent a series of standing cough stress tests in each of four postures: standing, crossing th...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Norton PA,Baker JE

    更新日期:1994-11-01 00:00:00

  • Correlation of uterine activity using the Term Guard monitor versus standard external tocodynamometry compared with the intrauterine pressure catheter.

    abstract::Uterine activity monitoring to detect preterm contractions and thus to manage patients in active labor is valuable to the clinician. Uterine activity measured by external devices using the guard ring principle or by standard tocodynamometers has been shown to be accurate concerning the frequency of uterine activity as...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Hess LW,McCaul JF,Perry KG,Howard PR,Morrison JC

    更新日期:1990-07-01 00:00:00

  • Fetal puncture during midtrimester amniocentesis.

    abstract::Four cases of fetal puncture during midtrimester amniocentesis are reported; in one instance the baby apparently sustained temporary neurologic damage. None of the lesions was detected at the initial neonatal examination. From our data and a review of the literature, we estimate that fetal puncture occurs in 1-3% of m...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Karp LE,Hayden PW

    更新日期:1977-01-01 00:00:00

  • Pathology slide review in gynecologic oncology.

    abstract:OBJECTIVE:To analyze the diagnostic accuracy and alteration in treatment planning from interinstitution (different institution) pathologic consultation. METHODS:We reviewed pathologic reports from 720 referred patients. The diagnosis rendered from a gynecologic pathologist was compared with the original diagnosis. Dis...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(98)00032-5

    authors: Santoso JT,Coleman RL,Voet RL,Bernstein SG,Lifshitz S,Miller D

    更新日期:1998-05-01 00:00:00

  • Impaired ultrasonographic cervical assessment after voiding: a randomized controlled trial.

    abstract:OBJECTIVE:To estimate whether the timing of bladder emptying affects focal myometrial contraction development and image adequacy. METHODS:Women at 14 0/7-32 0/7 weeks of gestation undergoing a transvaginal ultrasound examination from January 1, 2012, to September 1, 2012, were eligible for this blinded randomized cont...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/AOG.0b013e3182860b8d

    authors: Schnettler W,March M,Hacker MR,Modest AM,Rodriguez D

    更新日期:2013-04-01 00:00:00