Abstract:
OBJECTIVE:Postcesarean endometritis and wound infection remain significant morbidities, despite use of strategies to prevent these complications. We investigated the effect of preoperative vaginal preparation with povidone-iodine as a preventive intervention against postcesarean endometritis and wound infection. METHODS:A randomized controlled study was performed in 308 women undergoing nonemergent cesarean delivery. Subjects received either standard abdominal scrub alone or abdominal scrub with an additional vaginal preparation with povidone-iodine solution. All subjects received prophylactic antibiotic at the time of umbilical cord clamping. Each subject's postoperative course was reviewed for development of febrile morbidity (temperature > 38.0 degrees C), endometritis (temperature > 38.4 degrees C accompanied by fundal tenderness occurring beyond the first postoperative day, in the absence of evidence of other infection), and wound infection. RESULTS:Postcesarean endometritis occurred in 7.0% of subjects who received a preoperative vaginal preparation and 14.5% of controls (P < .05). There was no measurable effect of a vaginal scrub on the development of postoperative fever or wound infection. The adjusted odds ratio for developing endometritis after a vaginal preparation was 0.44 (95% confidence interval [CI] 0.193-0.997). Multivariate analysis showed an increased risk of developing endometritis in association with severe anemia (adjusted OR 4.26, 95% CI 1.568-11.582), use of intrapartum internal monitors (adjusted OR 2.84, 95% CI 1.311-6.136), or history of antenatal genitourinary infection (adjusted OR 2.9, 95% CI 1.265-6.596). CONCLUSION:Preoperative vaginal scrub with povidone-iodine decreases the incidence of postcesarean endometritis. This intervention does not seem to decrease the overall risk of postoperative fever or wound infection.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Starr RV,Zurawski J,Ismail Mdoi
10.1097/01.AOG.0000164032.16599.7esubject
Has Abstractpub_date
2005-05-01 00:00:00pages
1024-9issue
5 Pt 1eissn
0029-7844issn
1873-233Xpii
105/5/1024journal_volume
105pub_type
临床试验,杂志文章,随机对照试验abstract:OBJECTIVE:To analyze the influence of body mass on the outcome of surgery for urinary incontinence. METHODS:Among 291 women operated on for stress incontinence, 187 (64%) were available for follow-up at 5 years. Eighty women had anterior colporrhaphy, 49 anterior colporrhaphy with needle suspension of the bladder neck...
journal_title:Obstetrics and gynecology
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abstract:OBJECTIVE:To examine differences in clinical and pathologic characteristics between women undergoing hysterectomy who had had prior tubal sterilization and those who had not. METHODS:One thousand eight hundred fifty-one women undergoing hysterectomy were enrolled as part of a multicenter, prospective cohort study. We ...
journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章,多中心研究
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abstract::Topical 5-fluorouracil (5-FU) has proven effective in epidermoid cancers of the head and neck. Its effectiveness has been correlated with the ability of the patient's immunologic system to recognize new antigens. In this study, 8 patients with carcinoma in situ of the vulva were evaluated and treated with topical 5-FU...
journal_title:Obstetrics and gynecology
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abstract:OBJECTIVE:We sought to relate the risk of antepartum stillbirth to uterine artery Doppler flow velocimetry at 22-24 weeks. METHODS:Data were available from 30,519 unselected women from seven units in the UK who had uterine artery Doppler performed between 22 and 24 weeks of gestation. The risk of stillbirth (n=109) wa...
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abstract::The population of women within carceral systems is growing rapidly. A portion of these individuals are pregnant and will deliver while incarcerated. Although shackling laws for pregnant persons have improved, incarcerated patients are forced to labor without the support of anyone but a carceral officer and their medic...
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journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章
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journal_title:Obstetrics and gynecology
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journal_title:Obstetrics and gynecology
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journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2004-04-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章,随机对照试验
doi:10.1097/AOG.0b013e3181b8fa00
更新日期:2009-10-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
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更新日期:1991-11-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章,多中心研究
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更新日期:2006-10-01 00:00:00
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pub_type: 杂志文章,多中心研究
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更新日期:1999-06-01 00:00:00
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abstract::Laparoscopic tubal sterilization, using a Silastic band to occlude the tubal lumen, was performed on 224 patients. The incidence of complications was low and only 2 pregnancies occurred. Further evaluation by hysterosalpingography on 97 patients revealed 2 distinct images. The site of tubal occlusion was seen on lapar...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章
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journal_title:Obstetrics and gynecology
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更新日期:2020-10-01 00:00:00
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journal_title:Obstetrics and gynecology
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更新日期:1980-07-01 00:00:00
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更新日期:2015-05-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
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