Abstract：
OBJECTIVE:To investigate the relation between the biochemical markers of umbilical venous erythropoietin and umbilical arterial pH and morphologic placental abnormalities in fetal hypoxia. METHODS:Placentas from 300 high-risk newborn infants (gestational age 24-42 weeks) were examined macroscopically and microscopically following standardized criteria. The morphologic findings were correlated with the erythropoietin concentration in umbilical venous blood and with umbilical arterial pH at birth. Venous hematocrit and circulating nucleated red blood cells were measured in 112 of these infants during the first 6 hours of life. RESULTS:The umbilical venous erythropoietin concentration correlated significantly (r = 0.74) with the number of circulating nucleated red blood cells. In 26 placentas without morphologic abnormalities, the median (and 25th and 75th percentiles) erythropoietin concentration was 35.2 mU/mL (19.2-48.7) and umbilical arterial pH was 7.30 (7.20-7.33). The erythropoietin concentration was elevated significantly when placental examination showed evidence of acute villous circulatory disturbance (61.3 mU/mL; 24.2-125.1), fetal vasculopathy (85.6 mU/mL; 23.7-119.7), or chorioamnionitis with fetal reaction (51.3 mU/mL; 27.7-118.7). The erythropoietin concentration varied significantly with the stage of placental meconium phagocytosis; it was 62.7 mU/mL (16.3-125.9) if meconium phagocytosis was classified as recent, 128.2 mU/mL (44.4-1483.2) if it was classified as a few hours old, and 66.2 mU/mL (46.3-140.1) if it was classified as a few days old. Umbilical arterial pH was not altered significantly with different morphologic placental abnormalities. CONCLUSIONS:Fetal erythropoietin production is stimulated by hypoxia after a few hours' delay and leads to increased erythropoiesis. Placental examination combined with measurement of umbilical venous erythropoietin and umbilical arterial pH provides information about earlier fetal hypoxia.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Maier RF,Günther A,Vogel M,Dudenhausen JW,Obladen Msubject
Has Abstractpub_date
1994-07-01 00:00:00pages
81-7issue
1eissn
0029-7844issn
1873-233Xjournal_volume
84pub_type
杂志文章abstract：OBJECTIVE:To estimate whether and to what extent interbirth interval is associated with cesarean delivery. METHODS:This is a retrospective cohort study of 2,528 multiparous women who presented to labor and delivery at a single tertiary care obstetric hospital during an 18-month period. Women were grouped by their inte...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e31821c4368
更新日期：2011-07-01 00:00:00
abstract：OBJECTIVE:To evaluate the long-term outcome of patients with severe cervical intraepithelial neoplasia or squamous cell carcinoma in situ (CIN III) after cold-knife conization with clear margins. METHODS:A total of 4417 women (mean age 36, range 18-72 years) with histologically confirmed CIN III had cold-knife conizat...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(00)01174-1
更新日期：2001-03-01 00:00:00
abstract：:Fifteen fallopian tubes in which a previous ipsilateral eccyesis was managed by conservative surgical techniques were examined. The condition of the tube relative to the previous surgical management and the resolution of the previous implantation sites were correlated with the recurrent tubal pregnancy. All previous i...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1990-01-01 00:00:00
abstract：:Insulin-dependent diabetic women without adequate glucose control have a higher spontaneous abortion rate when compared with the general population. The present study examined whether the increased rate of spontaneous abortions in insulin-dependent diabetic women was associated with poor glycemic control in the early ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/00006250-198609000-00015
更新日期：1986-09-01 00:00:00
abstract：OBJECTIVE:To compare the efficacy and safety of routine electronic fetal monitoring (EFM) of labor with intermittent auscultation, using the results of published randomized controlled trials (RCTs). DATA SOURCES:We identified RCTs by searching the MED-LINE data base for the period 1966-1994, contacting experts, and re...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,评审
doi：
更新日期：1995-10-01 00:00:00
abstract：OBJECTIVE:To describe the incidence of pelvic floor dysfunction in transgender women undergoing gender-affirming vaginoplasty and outcomes in a program providing pelvic floor physical therapy (PT). METHODS:We conducted a retrospective, single-institution study on vaginoplasty patients between May 1, 2016, and February...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000003236
更新日期：2019-05-01 00:00:00
abstract：:A 22-month-old child with a large cyst of Gartner's duct suffered from recurrent episodes of urinary retention. Excision of such large symptomatic cysts has been recommended in the past. Marsupialization is discussed as an alternative to extensive excision. ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1988-09-01 00:00:00
abstract：OBJECTIVE:To estimate the incidence and identify the risk factors for pelvic organ prolapse repair after hysterectomy. METHODS:We conducted a case-control study. We identified 6,214 women who underwent hysterectomy in our gynecology department from 1982 to 2002. Cases (n=114) were women who required pelvic organ prola...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000278567.37925.4e
更新日期：2007-09-01 00:00:00
abstract：:In a low-prevalence population for sexually transmitted disease, accurate methods of identifying Neisseria gonorrhoeae infections are of paramount importance. Tests with low sensitivity are of concern to each practitioner. Of no less concern, however, are the possible social and emotional consequences of a false-posit...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1987-05-01 00:00:00
abstract：OBJECTIVE:To assess the associations between specific pregnancy complications and posttraumatic stress disorder based on neurobiologic and behavioral characteristics, using Michigan Medicaid claims data from 1994-1996. METHODS:Two thousand, two hundred nineteen female recipients of Michigan Medicaid who were of childb...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(00)01097-8
更新日期：2001-01-01 00:00:00
abstract：:The authors attempted to relate neonatal mortality to method of delivery in a series of 345 infants, weighing 700 to 1500 g, who were born in King County, Washington, from 1977 to 1979. Overall, 38% of infants delivered vaginally died as opposed to 32% of those with cesarean births. However, after adjustment for birth...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1984-08-01 00:00:00
abstract：:We evaluated the recovery of fertility and the relief of pain symptoms in a long-term follow-up of 42 women undergoing repetitive conservative surgery for recurrent endometriosis. The mean age of the patients was 31.1 +/- 4.3 years. At the time of their second operation the disease was stage IV in 14 women, stage III ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1991-03-01 00:00:00
abstract：:Over the past decades, the use of assisted reproductive technology (ART) has increased dramatically worldwide and has made pregnancy possible for many infertile couples. Although the perinatal risks that may be associated with ART and ovulation induction are much higher in multifetal gestations, even singletons achiev...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000001636
更新日期：2016-09-01 00:00:00
abstract：:An analysis was performed of malignant and host cells found in peritoneal fluids obtained during intraperitoneal chemotherapy and immunotherapy in patients with ovarian cancer. The concentration of malignant cells and the surgically documented response to the intraperitoneal treatment were correlated. Twenty-three pat...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1988-11-01 00:00:00
abstract：:The long-term follow-up is presented of three infants with vulvovaginal rhabdomyosarcoma treated at 10, 11, and 15 months of age by radical surgery, pelvic radiation therapy, and chemotherapy. Two patients developed colonic stricture requiring operative repair. One of these two patients also has urinary incontinence s...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1988-03-01 00:00:00
abstract：:Two hundred thirty-three cases of endometrial carcinoma were analyzed for DNA content using flow cytometry of cell nuclei extracted from archival paraffin blocks. The median follow-up time for the cases was 8.7 years. Aneuploidy, present in 18% of tumors overall, was associated with adverse histologic type, high grade...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1990-08-01 00:00:00
abstract：BACKGROUND:Alimentary tract duplications are rare congenital lesions that may arise at any location throughout the gastrointestinal tract. The most common site of enteric duplications is the ileum, with only 13% of cases occurring in the colon. CASE:Prenatal sonography at 39 weeks' gestation showed a cystic structure ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：2003-05-01 00:00:00
abstract：:The diagnosis of a cervical ectopic pregnancy is often made intraoperatively in the presence of extensive hemorrhage during attempted evacuation. In some cases, hysterectomy has been the necessary treatment to control bleeding. We report two cases of cervical pregnancy detected by ultrasound. Before pregnancy terminat...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1990-11-01 00:00:00
abstract：OBJECTIVE:To assess the gastrointestinal function and patient acceptability of early initiation of oral feeding after cesarean delivery. METHODS:Two hundred twenty-one healthy women delivered by cesarean were assigned in an alternating manner to receive either a high-protein, low-residue pudding initiated within 6 hou...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0029-7844(96)00049-x
更新日期：1996-06-01 00:00:00
abstract：OBJECTIVE:To establish the optimum oral daily dose of micronized medroxyprogesterone acetate, given in combination with a fixed oral dose of estrone (E1) sulfate as hormone replacement therapy, that provides endometrial protection and induces cessation of vaginal bleeding. METHODS:This multicenter, randomized, double-...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,多中心研究,随机对照试验
doi：10.1016/s0029-7844(98)00038-6
更新日期：1998-05-01 00:00:00
abstract：OBJECTIVE:To quantify the numbers of leukocytes in the normal cervix and relate these numbers to the diagnosis of cervicitis. METHODS:Isolated cell suspensions were prepared from cervical tissue recovered at hysterectomy from 37 women who had no obvious cervical disease. The percentages of CD45+ cells (leukocytes) in ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(98)00086-6
更新日期：1998-06-01 00:00:00
abstract：:Almost 50% of married female residents become pregnant during their residency. The desire to have a baby and a concern about age influence the decision to become pregnant. Career concerns, financial issues, and child care are less important. In addition, support of the faculty or house staff is not a crucial factor in...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1988-09-01 00:00:00
abstract：BACKGROUND:Hyperemesis gravidarum may lead to hypovolemia and substantial electrolyte abnormalities, including hypokalemia. Hypokalemia, when profound, may result in rare consequences, such as rhabdomyolysis. CASE:A 20-year-old woman with hyperemesis gravidarum at 19 weeks of gestation presented with extreme leg weakn...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000001418
更新日期：2016-07-01 00:00:00
abstract：:Rates of perforation for different types of IUDs vary from 1 per 150 insertions with the bow to 1 per 2500 with the loop. Incidence of perforation varies with insertion technic. Not all perforations occur at the time of insertion but most do. These perforations may be partial or complete, with or without symptoms, ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1972-08-01 00:00:00
abstract：:To assess the problem of continuing atenolol in a breast-feeding mother with hypertension associated with thyrotoxicosis, studies were performed to determine simultaneous plasma and breast milk concentrations of atenolol after a single dose of 50 mg and on continuous therapy of varying weekly dosages. Peak atenolol co...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1984-03-01 00:00:00
abstract：OBJECTIVE:To test the effectiveness of intraperitoneal local anesthesia in relieving postoperative pain after laparoscopic sterilization. METHODS:In a double-blind, placebo-controlled randomized study of two groups of 25 subjects each, women scheduled for tubal sterilization under general anesthesia received 80 mL of ...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：
更新日期：1994-11-01 00:00:00
abstract：OBJECTIVE:To determine changes in length of incompetent cervices after cerclage, using transvaginal ultrasound. METHODS:Patients were enrolled in a prospective, observational study under an Institutional Review Board-approved protocol. McDonald or Shirodkar sutures were placed according to physician preference. Pre- a...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(98)00568-7
更新日期：1999-07-01 00:00:00
abstract：OBJECTIVE:To examine the effect of high-fiber diet on constipation in women with pelvic floor disorders. METHODS:This was a study of a prospective cohort of 41 consecutive women presenting to a tertiary care facility for pelvic floor disorders with a complaint of constipation from March 2005 to September of 2005. Pati...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000308660.48204.7f
更新日期：2008-04-01 00:00:00
abstract：OBJECTIVE:To evaluate the efficacy of an integrated multiple risk intervention, delivered mainly during pregnancy, in reducing such risks (cigarette smoking, environmental tobacco smoke exposure, depression, and intimate partner violence) postpartum. METHODS:Data from this randomized controlled trial were collected pr...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,多中心研究,随机对照试验
doi：10.1097/AOG.0b013e3181834b10
更新日期：2008-09-01 00:00:00
abstract：:Serial measurements of amniotic fluid volume were made using a tracer dilution technique in sheep during the last half of gestation. No consistent trends were observed in amniotic fluid volume changes over this period. Disappearance of tracer-labeled urea and water from the amniotic fluid was observed at various gesta...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1984-09-01 00:00:00
