Abstract:
:Insulin-dependent diabetic women without adequate glucose control have a higher spontaneous abortion rate when compared with the general population. The present study examined whether the increased rate of spontaneous abortions in insulin-dependent diabetic women was associated with poor glycemic control in the early postconceptional period or close to the abortive event itself. Measurements of glycohemoglobin A1 at eight to nine weeks' gestation provide retrospective indexes of glucose control during the early postconceptional period, whereas measurement of glycosylated serum albumin and serum protein at the same time reflects short-term glycemic control before the abortive event. This study evaluated 84 consecutive pregnancies occurring in 68 insulin-dependent diabetic women; 66 pregnancies progressed beyond 20 weeks with no malformation or death, and 18 pregnancies terminated in spontaneous abortions before 20 weeks' gestation. The mean glycohemoglobin A1 concentrations of women experiencing spontaneous abortions were significantly greater than that of women who did not abort (P less than .05). In contrast, maternal glycosylated proteins and glycosylated albumin concentrations did not differ between groups. The authors suggest that poor control of diabetes in the early conceptional period, rather than that just before abortion, increases the risk of spontaneous abortion.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Miodovnik M,Mimouni F,Tsang RC,Ammar E,Kaplan L,Siddiqi TAdoi
10.1097/00006250-198609000-00015subject
Has Abstractpub_date
1986-09-01 00:00:00pages
366-9issue
3eissn
0029-7844issn
1873-233Xjournal_volume
68pub_type
杂志文章abstract::Preterm birth is the leading cause of neonatal mortality and a substantial portion of all birth-related short- and long-term morbidity. Spontaneous preterm labor is responsible for more than half of preterm births. Its management is the topic of this review. Although there are many maternal characteristics associated ...
journal_title:Obstetrics and gynecology
pub_type: 杂志文章,评审
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更新日期:2002-11-01 00:00:00
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journal_title:Obstetrics and gynecology
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journal_title:Obstetrics and gynecology
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doi:
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journal_title:Obstetrics and gynecology
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更新日期:1981-05-01 00:00:00
abstract:OBJECTIVE:To examine some of the controversy that still exists regarding the definition and management of microinvasive or early invasive cervical carcinoma, in particular, the current concepts regarding the definition of these conditions and their inclusion into the staging system for cervical cancer. DATA SOURCES:A ...
journal_title:Obstetrics and gynecology
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abstract:OBJECTIVE:Among all women with pelvic inflammatory disease (PID), prevention of adverse reproductive consequences appears to be similarly achieved by outpatient treatment and inpatient treatment. We assessed whether outpatient is as effective as inpatient treatment in relevant age, race, and clinical subgroups of women...
journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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journal_title:Obstetrics and gynecology
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journal_title:Obstetrics and gynecology
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doi:10.1016/s0029-7844(97)00298-6
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章,随机对照试验
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更新日期:2014-06-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
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更新日期:2005-02-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1993-05-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/AOG.0000000000004247
更新日期:2021-02-01 00:00:00
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doi:10.1097/AOG.0000000000003106
更新日期:2019-03-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0029-7844(97)00049-5
更新日期:1997-04-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
更新日期:1981-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1097/01.AOG.0000114974.40512.c9
更新日期:2004-03-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1016/s0029-7844(00)01079-6
更新日期:2000-12-01 00:00:00
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journal_title:Obstetrics and gynecology
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:10.1097/00006250-198609000-00003
更新日期:1986-09-01 00:00:00
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journal_title:Obstetrics and gynecology
pub_type: 杂志文章
doi:
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doi:10.1097/AOG.0000000000002142
更新日期:2017-08-01 00:00:00
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更新日期:1994-05-01 00:00:00
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更新日期:2000-11-01 00:00:00
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pub_type: 杂志文章,meta分析,评审
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更新日期:2015-06-01 00:00:00
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