Abstract:
:Contrast thresholds for detection of stationary and flickering gratings were measured behaviorally for each eye of cats raised with induced convergent strabismus. The performance of the deviating eye was inferior to that of the nondeviating eye when test patterns were stationary. Flicker served to reduce the performance difference between the eyes in two cats but not in a third. These results suggest that strabismus amblyopia may not result from deficits within a single class of neurons. In all strabismic cats the contrast sensitivity of the nondeviating eye was significantly reduced relative to normal cats. These behavioral findings, including the deficits found bilaterally, correspond very well with results from cortical recordings from these and other strabismic cats presented in the preceding paper (7).
journal_name
J Neurophysioljournal_title
Journal of neurophysiologyauthors
Holopigian K,Blake Rdoi
10.1152/jn.1983.50.1.287subject
Has Abstractpub_date
1983-07-01 00:00:00pages
287-96issue
1eissn
0022-3077issn
1522-1598journal_volume
50pub_type
杂志文章abstract::Midcervical spinal interneurons form a complex and diffuse network and may be involved in modulating phrenic motor output. The intent of the current work was to enable a better understanding of midcervical "network-level" connectivity by pairing the neurophysiological multielectrode array (MEA) data with histological ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00638.2016
更新日期:2017-03-01 00:00:00
abstract::The brain can precisely encode the temporal relationship between tactile inputs. While behavioural studies have demonstrated precise interfinger temporal judgments, the underlying neural mechanism remains unknown. Computationally, two kinds of neural responses can act as the information source. One is the phase-locked...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00790.2015
更新日期:2016-03-01 00:00:00
abstract::Weight predictions used to scale lifting forces adapt quickly when repeatedly lifting unusually weighted objects and are readily updated by explicit information provided about weight. In contrast, weight predictions used when making perceptual judgments about weight are more resistant to change and are largely unaffec...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01051.2015
更新日期:2016-09-01 00:00:00
abstract::In the cochlear nucleus (CN) of awake mustached bats, single- and two-tone stimuli were used to examine how responses in major CN subdivisions contribute to spectrotemporal integrative features in the inferior colliculus (IC). Across CN subdivisions, the proportional representation of frequencies differed. A striking ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00634.2005
更新日期:2006-01-01 00:00:00
abstract::The gain of the vertical vestibuloocular reflex (VVOR), defined as eye velocity/head velocity was adapted in squirrel monkeys by employing visual-vestibular mismatch stimuli. VVOR gain, measured in the dark, could be trained to values between 0.4 and 1.5. Single-unit activity of vertical zone Purkinje cells was record...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.2001.85.5.2267
更新日期:2001-05-01 00:00:00
abstract::1. "Unmasking" of weak synaptic connections has been suggested as a mechanism for the early changes in cortical topographic maps that follow alterations of sensory activity. For such a mechanism to operate, convergent sensory inputs must already exist in the normal cortex. 2. We tested for topographic and cross-modali...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1991.66.3.688
更新日期:1991-09-01 00:00:00
abstract::1. A method for adapting a standard stereotaxic frame for use with neonatal rats as young as postnatal day 1 (PD 1) was devised, and single-unit extracellular recordings were obtained from neurons in the locus ceruleus (LC) in urethan-anesthetized rats during different stages in development from PD 1 to PD 34. 2. The ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1987.58.3.510
更新日期:1987-09-01 00:00:00
abstract::Neurons in the inferior colliculus (IC) process acoustic information converging from inputs from almost all nuclei of the auditory brain stem. Despite its importance in auditory processing, little is known about the distribution of ion currents in IC neurons, namely the hyperpolarization-activated current Ih. This cur...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00375.2003
更新日期:2003-12-01 00:00:00
abstract::1. It was the aim of this study to show that nucleus Z of the cat medulla acts as a relay between the spinal cord and the ventral lateral (VL) nucleus of the motor thalamus. For this purpose, extracellular recordings were made from neurons that were antidromically identified by stimulation in the rostral thalamus, par...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1993.69.5.1607
更新日期:1993-05-01 00:00:00
abstract::In human spinal cord injury (SCI), imposed unilateral hip movements trigger multijoint, coordinated reflexes that might incorporate interneuronal circuitry involved in normal motor control, such as neural pathways associated with the reflex control of locomotion. To further investigate the complexity of these hip-trig...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00461.2007
更新日期:2007-10-01 00:00:00
abstract::1. The behavior of the combined eye-head gaze saccade mechanism was investigated in the rhesus monkey under both normal circumstances and in the presence of perturbations delivered to the head by a torque motor. Animals were trained to follow a target light that stepped at regular intervals through an angle of 68 degr...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1990.64.6.1873
更新日期:1990-12-01 00:00:00
abstract::An important question in neuroscience is whether and how temporal patterns and fluctuations in neuronal spike trains contribute to information processing in the cortex. We have addressed this issue in the memory-related circuits of the prefrontal cortex by analyzing spike trains from a database of 229 neurons recorded...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00949.2002
更新日期:2003-11-01 00:00:00
abstract::Most of what we know about the neural control of gaze comes from experiments in head-fixed animals, but several "head-free" studies have suggested that fixing the head dramatically alters the apparent gaze command. We directly investigated this issue by quantitatively comparing head-fixed and head-free gaze trajectori...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00330.2003
更新日期:2003-10-01 00:00:00
abstract::In layer 2/3 of neocortex, brief trains of action potentials in pyramidal neurons (PNs) induce the mobilization of endogenous cannabinoids (eCBs), resulting in a depression of GABA release from the terminals of inhibitory interneurons (INs). This depolarization-induced suppression of inhibition (DSI) is mediated by ac...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00817.2007
更新日期:2007-11-01 00:00:00
abstract::1. We have studied the responses of neurons in the lateral and descending vestibular nuclei of decerebrate cats to stimulation of neck receptors, produced by rotating the body in vertical planes with the head stationary. The responses to such neck stimulation were compared with the responses to vestibular stimulation ...
journal_title:Journal of neurophysiology
pub_type: 临床试验,杂志文章
doi:10.1152/jn.1988.60.5.1765
更新日期:1988-11-01 00:00:00
abstract::Recent studies have reported that human subjects show varying degrees of ability to use contextual cues to recall the motor skills required to compensate for different dynamic external force fields during arm movements. In particular, the subjects showed little or no ability to use color cues to adjust motor outputs i...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00779.2002
更新日期:2003-02-01 00:00:00
abstract::Membrane retrieval following exocytosis in synaptic terminals is fast and compensatory, however, little is known about the factors that regulate or contribute to this special form of endocytosis. We used whole-terminal capacitance measurements to examine the effect of hydrostatic pressure on compensatory endocytosis i...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00267.2002
更新日期:2002-11-01 00:00:00
abstract::Several models exist for explaining primary visual cortex (V1) orientation tuning. The modified feedforward model (MFM) and the recurrent model (RM) are major examples. We have implemented these two models, at the same level of detail, alongside a few newer variations, and thoroughly compared their receptive-field str...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00015.2005
更新日期:2006-07-01 00:00:00
abstract::Processing of temporal information is key in auditory processing. In this study, we recorded single-unit activity from rat auditory cortex while they performed an interval-discrimination task. The animals had to decide whether two auditory stimuli were separated by either 150 or 300 ms and nose-poke to the left or to ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00381.2013
更新日期:2013-11-01 00:00:00
abstract::The ovulation hormone-producing caudodorsal cells (CDCs) of the pond snail Lymnaea stagnalis form two clusters of electrotonically coupled cells, each containing a few specialized (ventral) cells that connect the clusters. The hormone is secreted during a pacemaker-driven discharge. The CDCs receive a biphasic choline...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1983.49.6.1392
更新日期:1983-06-01 00:00:00
abstract::The development of synaptic interconnections between the cerebellum and inferior olive, the sole source of climbing fibers, could contribute to the ontogeny of certain forms of motor learning (e.g., eyeblink conditioning). Purkinje cell complex spikes are produced exclusively by climbing fibers and exhibit short- and ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00481.2003
更新日期:2003-10-01 00:00:00
abstract::1. The stiffness during the initial portion of a ramp stretch was measured in cat peroneus longus muscle at rest and during maximal tetanic contractions produced by increasing numbers of motor units of the same type [slow (S), fast fatigue resistant (FR), or fast fatigable (FF)]. 2. This initial ramp stiffness was def...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1990.64.6.1724
更新日期:1990-12-01 00:00:00
abstract::In this study we present further evidence supporting the reciprocal nature of output effects on forearm flexor and extensor muscles from single corticomotoneuronal (CM) cells. Spike-triggered averaging of rectified EMG activity was used to test the output effects of 105 motor cortex cells in two rhesus monkeys (Macaca...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1985.53.4.959
更新日期:1985-04-01 00:00:00
abstract::Using microstimulation to imprint meaningful activity patterns into intrinsically highly interconnected neuronal substrates is hampered by activation of fibers of passage leading to a spatiotemporal "blur" of activity. The focus of the present study was to characterize the shape of this blur in the neocortex to arrive...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00245.2003
更新日期:2003-11-01 00:00:00
abstract::The majority of cerebral signals destined for the cerebellum are handed over by the pontine nuclei (PN), which thoroughly reorganize the neocortical topography. The PN maps neocortical signals of wide-spread origins into adjacent compartments delineated by spatially precise distribution of cortical terminals and posts...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01060.2005
更新日期:2006-06-01 00:00:00
abstract::Corneal-responsive neurons were recorded extracellularly in two regions of the spinal trigeminal nucleus, subnucleus interpolaris/caudalis (Vi/Vc) and subnucleus caudalis/upper cervical cord (Vc/C1) transition regions, from methohexital-anesthetized male rats. Thirty-nine Vi/Vc and 26 Vc/C1 neurons that responded to m...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1999.82.5.2092
更新日期:1999-11-01 00:00:00
abstract::1. The lateral geniculate nucleus is the primary thalamic relay for the transfer of retinal signals to the visual cortex. Geniculate cells are heavily innervated from nonretinal sources, and these modify retinogeniculate transmission. A major ascending projection to the lateral geniculate nucleus arises from cholinerg...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1995.73.6.2428
更新日期:1995-06-01 00:00:00
abstract::Mechanoelectric transducer (MET) channels, located near stereocilia tips, are opened by deflecting the hair bundle of sensory hair cells. Defects in this process result in deafness. Despite this critical function, the molecular identity of MET channels remains a mystery. Inherent channel properties, particularly those...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01178.2011
更新日期:2012-05-01 00:00:00
abstract::1. Retzius (R) neurons of the fifth and sixth segmental ganglia of the leech, called R(5,6) neurons are specialized to innervate the adjacent reproductive organs and are morphologically and functionally distinct from R neurons of standard ganglia [R(x) cells]. In this study the electrical properties of the R(x) and R(...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1995.73.3.957
更新日期:1995-03-01 00:00:00
abstract::The abundance of nitric oxide (NO) synthesizing enzymes identified in the vertebrate retina highlight the importance of NO as a signaling molecule in this tissue. Here we describe opposing actions of NO on the rod and cone photoreceptor synapse. Depolarization-induced increases of calcium concentration in rods and con...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00606.2003
更新日期:2004-07-01 00:00:00