Serum xanthine oxidase in breast carcinoma.

abstract：:A 10-year old Nigerian boy was admitted to hospital with a history of swelling in the neck, change of voice, dysphagia and dyspnoea of 2 weeks duration. He died on the 2nd day of admission. Autopsy revealed a thymoma infiltrating the thyroid, trachea and neck muscles and transforming the tracheal lumen into a slit lik...

journal_title：Neoplasma

authors： Suseelan AV,Ikerionwu SE,Ojukwu JO

更新日期：1979-01-01 00:00:00

abstract：:The results of studies of a co-carcinogenic effect of two human infectious viruses in tissue culture are reported here. Viable vaccinia virus actively replicating in the cells of primary BALB/c tissue culture and in a number of continuous murine cell lines has been shown to induce in them expression of major structura...

journal_title：Neoplasma

authors： Mazurenko NP,Merekalova ZI,Pavlish OA,Bykovsky AF,Kurzman MJ,Mazurenko NN

更新日期：1981-01-01 00:00:00

abstract：:The histochemical properties of mucus in 48 diffuse type gastric carcinomas and in 46 intestinal type gastric cancers were investigated. In the diffuse type there was a prevalence of intracellular secretion of mucopolysaccharides with a significantly larger portion of sulfated mucopolysaccharides. Acid mucopolysacchar...

journal_title：Neoplasma

authors： Tichá V,Jansa P,Tichý M

更新日期：1988-01-01 00:00:00

abstract：:The distribution of peanut agglutinin (PNA) receptors, nonspecific cross-reacting antigen (NCA) molecule and 3-fucosyl-N-acetyllactosamine (FAL) in myeloid leukemic cells isolated by density gradient centrifugation was compared using immunofluorescence test (IF). Patients with acute myelocytic leukemias (AML) type M2 ...

journal_title：Neoplasma

authors： Noworolska A,Slesak B,Harłonzińska A,Richter R

更新日期：1991-01-01 00:00:00

abstract：:This paper summarizes preliminary results of combining suicide gene strategy (E. coli cytosine deaminase gene--CD) with immunotherapy (murine interleukin-4 gene) for treatment of experimental B16(F10) melanomas implanted into C57Bl/6 mice. The best therapeutic results, inhibition of tumor growth and prolonged survival...

journal_title：Neoplasma

authors： Missol-Kolka E,Sochanik A,Szala S

更新日期：1998-01-01 00:00:00

abstract：:Multiple primary tumors are not rare: they are encountered in 3-5% of malignant tumors. They are particularly frequent in the head and neck [20]. They are most often met with secondary malignant tumors; triple tumors occur in only 0.5%, quadruple tumors in 0.3% of malignant tumors. The possibility of developing a seco...

journal_title：Neoplasma

authors： Németh Z,Czigner J,Iván L,Ujpál M,Barabás J,Szabó G

更新日期：2002-01-01 00:00:00

abstract：:A group of 54 patients with the original diagnosis of polycythemia vera were subjected to cytogenetic examination. Six (17.6%) of the 34 cases examined in the period of the advanced phase of the polycythemia vera had a chromosomal change. Thirteen (65%) of the 20 patients undergoing the cytogenetic examination in the ...

journal_title：Neoplasma

authors： Jarosová M,Indrák K,Dusek J,Kapustová M

更新日期：1988-01-01 00:00:00

abstract：:Extracellular adenosine is a key signaling molecule which mediates immune suppression, angiogenesis, and regulates cancer cells growth. The effect of adenosine on cervical cancer cells migration and invasion has not been well studied. In the current study, we used Hela and SiHa cell lines to evaluate the effects of ad...

journal_title：Neoplasma

authors： Gao ZW,Wang HP,Dong K,Lin F,Wang X,Zhang HZ

更新日期：2016-01-01 00:00:00

abstract：:The immunogenic properties of MC-induced and not metastasizing tumors were tested in inbred Wistar and August strains by the aid of lymphocyte stimulation in syngeneic draining lymph nodes in the comparison with the opposite ones. The lymphocyte stimulation was estimated in vitro by the spontaneous incorporation of 3H...

journal_title：Neoplasma

authors： Ryzewska AG,Rybicka M,Kania A,Dabrowski M

更新日期：1980-01-01 00:00:00

abstract：:Oral cancer is one of the common cancers worldwide, among which over 90% are oral squamous cell carcinomas (OSCC). MicroRNAs act as critical regulators of cancer development and progression. MiR-103a-3p has been reported to be upregulated in OSCC patients and closely correlated to poor prognosis, yet its roles in the ...

journal_title：Neoplasma

authors： Zhang G,Chen Z,Zhang Y,Li T,Bao Y,Zhang S

更新日期：2020-05-01 00:00:00

abstract：:The results from our investigations concerning the secretory activity of interleukin 10 (IL-10) by two transplantable melanoma cells showed that a spontaneous alteration of the native-melanotic line into an amelanotic form and the tumor progression connected with it, were accompanied by a 6-fold decrease of the IL-10 ...

journal_title：Neoplasma

authors： Kozłowska K,Zarzeczna M,Cichorek M,Wójcik S

更新日期：2003-01-01 00:00:00

abstract：:HCC is one of the leading causes of death worldwide. Liver transplantation including living donor transplantation is the best available treatment. We have analyzed our experience with LDLT in patients with HCC and HCV in order to determine if alpha feto-protein (AFP) is a better predictor of recurrence than the tumor ...

journal_title：Neoplasma

authors： Komorowski AL,Hsu CC,Julka KD,Vasavada B,Lin CC,Wang CC,Chen CL

更新日期：2018-03-14 00:00:00

abstract：:Authors evaluated the prevalence of symptoms of the metabolic syndrome and insulin resistance in 25 patients with adrenal incidentalomas (10 men, 15 women) of the mean age 57.9+/-15 years. 15 patients had adrenal adenoma determined by CT or MR scan and 10 had unilateral or bilateral hyperplasia. The prevalence of obes...

journal_title：Neoplasma

authors： Lazúrová I,Dudásová D,Wagnerová H,Dravecká I,Petrásová D

更新日期：2006-01-01 00:00:00

abstract：:Oxaliplatin is commonly used in managing malignancy, including colorectal cancer. While treatment often fails due to decreased drug sensitivity, the mechanisms involved are not clear. In this study, we investigate how exosomal miR-19b participates in oxaliplatin sensitivity and then prove that miR-19b down-regulates o...

journal_title：Neoplasma

authors： Gu YY,Yu J,Zhang JF,Wang C

更新日期：2019-01-15 00:00:00

abstract：:The possible association between cigarette smoking and the risk of benign breast disease (BBD) was assessed in a case-control study conducted in Gdańsk, Poland, between 1990 and 1994. The study compared 160 women with newly diagnosed BBD admitted to the Gdańsk Cancer Outpatients Clinic and 160 controls, women from out...

journal_title：Neoplasma

authors： Dziewulska-Bokiniec A

更新日期：1995-01-01 00:00:00

abstract：:Nasopharyngeal carcinoma (NPC) is a rare malignancy in the Czech Republic and Slovakia, with the standardized incidence rate of < 1:100000 person-years. Viral status of NPC in these non-endemic Eastern European regions is currently unknown. In a retrospective study, we evaluated the presence of EBV and HPV in 62 NPC c...

journal_title：Neoplasma

authors： Svajdler M Jr,Kaspirkova J,Mezencev R,Laco J,Torday T,Dubinsky P,Straka L,Ondic O,Michal M,Skalova A

更新日期：2016-01-01 00:00:00

abstract：:Immunohistochemistry (IE) and polymerase chain reaction (PCR) are tools enabling to find small number of tumor cells in lymph nodes (LNs) or peripheral blood. Perhaps these methods will allow early detection of cell dissemination and refine risk group within papillary thyroid cancer (PTC) that might benefit from more ...

journal_title：Neoplasma

authors： Kaczka K,Jakubiak-Wielganowicz M,Zawlik I,Ziolkowski R,Kuzdak K,Pomorski L

更新日期：2008-01-01 00:00:00

abstract：:In a series of 25 patients with cervical carcinoma and 35 patients with vulvar carcinoma, clinically classified (FIGO) as Stage I and Ib, respectively, DNA ploidy and S-phase cell fraction were estimated in paraffin-embedded samples of the primary tumors and their metastases by means of flow cytometry (FCM). The two g...

journal_title：Neoplasma

authors： Siracký J,Kysela B,Siracká E

更新日期：1989-01-01 00:00:00

abstract：:Possibilities of combined radioprotection, using preirradiation WR-2721 administration and post- or preirradiation Broncho-Vaxom administration in lethally whole-body gamma-irradiated mice were investigated. Combined modality treatments were more effective than individual treatments alone. The ameliorative influence o...

journal_title：Neoplasma

authors： Macková NO,Fedorocko P

更新日期：1995-01-01 00:00:00

abstract：:Human immediate early response 2 (IER2) has been implicated in tumor cell motility and metastasis; however, the underlying mechanisms in hepatocellular carcinoma (HCC) metastasis remain to be clarified. In this study, we demonstrate that dysregulation of IER2 was shown in HCC clinical samples, and IER2 expression resu...

journal_title：Neoplasma

authors： Xu X,Zhou W,Chen Y,Wu K,Wang H,Zhang J,Zhou Y,Zeng J,Yang J,Deng Z,Zhang Y,Shen W

更新日期：2020-05-01 00:00:00

abstract：UNLABELLED:Oncolytic viruses are examined to serve as anticancer therapeutics. It is expected that in addition to direct oncolytic effect their action will also help eliciting a solid antitumor immunity. In presented series of experiments we have employed two HPV16-transformed mouse (strain C57/B6) cell lines, TC-1 and...

journal_title：Neoplasma

authors： Figova K,Sobotkova E,Duskova M,Ludvikova V,Vonka V,Eckschlager T

更新日期：2010-01-01 00:00:00

abstract：:Helicase POLQ-like (HELQ), an ATP-dependent 3'-5' DNA helicase, plays pivotal roles in DNA processing, such as DNA replication, recombination and repair. The recent discovery of HELQ in mouse model and human cancer cell reveal that genetic alteration of HELQ is involved in cancer susceptibility and subfertility. Here ...

journal_title：Neoplasma

authors： Han X,Zhao L,Li X

更新日期：2016-01-01 00:00:00

abstract：:The anti-tumor effects of i.p. administered cyclooxygenase inhibitor - diclofenac and i.v. administered liposomal muramyl tripeptide phosphatidylethanolamine (MTP-PE) were investigated using a s.c. growing murine fibrosarcoma tumor. Tumor growth was assessed by measuring tumor volumes and survival of the mice. Both of...

journal_title：Neoplasma

authors： Fedorocko P,Hoferová Z,Hofer M,Brezáni P

更新日期：2003-01-01 00:00:00

abstract：:Cisplatin-based chemotherapy is highly effective in advanced seminoma, but at the cost of a considerable toxicity. The response rate of carboplatin is comparable with cisplatin combinations but the relapse rate is higher. Our study assesses the efficacy and the toxicity of the combination of carboplatin and cyclophosp...

journal_title：Neoplasma

authors： Mardiak J,Sálek T,Sycova-Milá Z,Sufliarsky J,Baláz M,Koza I

更新日期：2000-01-01 00:00:00

abstract：:In a series of 52 biopsy specimens (31 endometrial carcinomas, 10 atypical endometrial hyperplasias, and 11 cases of normal endometrium), DNA ploidy and S-phase cell fraction were estimated in paraffin-embedded material. DNA aneuploidy was detected in 2 of the 10 atypical endometrial hyperplasias and 7 of the 31 endom...

journal_title：Neoplasma

authors： Kysela B,Siracký J,Redecha M,Bárdos A

更新日期：1990-01-01 00:00:00

abstract：:Prolonged lifespan of monoclonal lymphocytes in B-cell lymphocytic leukemia (B-CLL) arises from their resistance to programmed cell death. In contrast, when cultured in vitro, B-CLL tumour cells rapidly undergo apoptosis. There is mounting evidence that P-glycoprotein (P-gp), an adenosine triphosphate-binding cassette...

journal_title：Neoplasma

authors： Jamroziak K,Smolewski P,Cebula B,Szmigielska-Kaplon A,Darzynkiewicz Z,Robak T

更新日期：2004-01-01 00:00:00

abstract：:We processed data of 79 patients (pts) with malignant lymphoma from the National Registry of haematopoietic stem cell transplants conducted between 1997 and 2006. The haematopoietic stem cell donor in 48 pts was an HLA matched relative, and in 30 pts an unrelated volunteer. Sixty (77%) pts were transplanted with reduc...

journal_title：Neoplasma

authors： Valkova V,Benesova K,Vitek A,Faber E,Mayer J,Zak P,Trneny M

更新日期：2009-01-01 00:00:00

abstract：:Currently, mechanisms leading to both apoptosis induction and the development of hormone-independence of prostate carcinoma cells are intensively studied. Attention is also given to the possibility of restoring cell sensitivity to hormone-antagonists. The present study focuses on the effect of the combined synthetic c...

journal_title：Neoplasma

authors： Knillová J,Bouchal J,Hlobilková A,Strnad M,Kolár Z

更新日期：2004-01-01 00:00:00

abstract：:Up to 19--20 fractions of separate RNA species and groups have been revealed in malignant tumors of the stomach and mucous membrane of patients with stomach cancer, ulcer and polyposis of the stomach by means of the method of analytical and preparative electrophoresis in 2.5% polyacrylamide gel. A more intensive incor...

journal_title：Neoplasma

authors： Seitz JF,Kalinvosky VP

更新日期：1976-01-01 00:00:00

abstract：:The clinical significance of thymosin β4 (Tβ4) expression in bladder transitional cell carcinoma (BTCC) remains unclear. The present study assessed the relationship between the expression of Tβ4 protein and the clinicopathological features, as well as the prognosis of bladder cancer patients. Tβ4 protein expression in...

journal_title：Neoplasma

authors： Wang ZY,Zhang W,Yang JJ,Song DK,Wei JX,Gao S

更新日期：2016-01-01 00:00:00