Abstract：
BACKGROUND:Active surveillance systems are effective in reducing health care-associated infections caused by methicillin-resistant Staphylococcus aureus (MRSA). Nonetheless, some patients develop MRSA infection despite control measures. We tried to identify risk factors related to the appearance of MRSA at sites other than the nasal fossa in patients who were nasal carriers of MRSA. METHODS:A retrospective case-control study was conducted in an active surveillance program for MRSA between January 2009 and December 2010 at a Spanish teaching hospital. Cases were patients with MRSA in the anterior nares and a length of stay of at least 5 days who developed MRSA-positive clinical culture after decolonization treatment had started. Controls were patients with the same characteristics as the case group, except that they did not develop MRSA-positive clinical culture as verified by negative clinical cultures. RESULTS:After intrinsic and extrinsic risk factors were analyzed, the emergence of mupirocin-resistant MRSA clones after decolonization treatment, and residence in a nursing home were marginally significant in the univariate analysis. The detection of the emergence of mupirocin-resistant MRSA clones was independently associated with the detection of MRSA in other clinical locations. CONCLUSIONS:In an active surveillance program for MRSA it is important to determine the mupirocin susceptibility of the isolates to determine appropriate treatment and to verify negativity after decolonizing treatment has been completed.
journal_name
Am J Infect Controljournal_title
American journal of infection controlauthors
Hernández-Porto M,Castro B,Ramos MJ,Arias A,Aguirre-Jaime A,Lecuona Mdoi
10.1016/j.ajic.2014.03.011subject
Has Abstractpub_date
2014-07-01 00:00:00pages
e75-9issue
7eissn
0196-6553issn
1527-3296pii
S0196-6553(14)00205-3journal_volume
42pub_type
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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doi：10.1016/j.ajic.2008.05.011
更新日期：2009-03-01 00:00:00
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journal_title：American journal of infection control
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doi：10.1067/mic.2003.64
更新日期：2003-04-01 00:00:00
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journal_title：American journal of infection control
pub_type： 杂志文章
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
pub_type： 杂志文章
doi：10.1016/j.ajic.2014.07.011
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abstract：:Handwashing is the single most important procedure in the prevention of nosocomial infections and yet it remains the most violated of all infection control procedures. With a sequential intervention study in an intensive care unit we have demonstrated that poor handwashing practices are associated with a high nosocomi...
journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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journal_title：American journal of infection control
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abstract：:A national survey was conducted during July to September 2009 to determine tuberculosis (TB) prevention activities, problems, and support needed of Thai hospitals. Ninety-seven percent of hospitals established TB isolation policy, 96.3% provided guidelines for caring of TB patients, 95% and 91.8% provided prevention o...
journal_title：American journal of infection control
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doi：10.1016/j.ajic.2013.09.019
更新日期：2014-03-01 00:00:00
