Abstract：
:Thirty-four patients using intrauterine contraceptive devices and experiencing excessive menstrual bleeding (more than 80 ml average loss for 2 cycles) were treated with the prostaglandin synthetase inhibitor naproxen. The trial was conducted according to a double-blind placebo-controlled crossover design. Each patient received 2 of 3 treatments: naproxen in high dose (1250 mg/day for 5 days), naproxen in low dose (500-mg loading dose, than 750 mg/day for 5 days), or placebo. Each treatment was taken during 2 consecutive menstruations. When all data were pooled, statistically significant reduction in menstrual bleeding was found with both high- and low-dose naproxen treatment compared with placebo therapy (P < .002). Low- and high-dose naproxen reduced menstrual blood loss by 22% and 32%, respectively, whereas the change with placebo was minimal. Although the dose had no significant effect on mean menstrual loss, the number of treatment cycles in which menstrual blood loss was reduced by 50% as compared with pretreatment cycles strongly suggested a dose response. In almost 60% of naproxen-treated cycles, mean menstrual blood loss was less than 80 ml, whereas during placebo-treated cycles the distribution of menstrual loss was similar to that of control cycles.
journal_name
Obstet Gynecoljournal_title
Obstetrics and gynecologyauthors
Davies AJ,Anderson AB,Turnbull ACsubject
Has Abstractpub_date
1981-01-01 00:00:00pages
74-8issue
1eissn
0029-7844issn
1873-233Xjournal_volume
57pub_type
临床试验,杂志文章abstract：:Comparing and contrasting two patients with pseudocyesis made it clear that differing psychodynamic factors specific to each patient resulted in divergent ways in which they sought out and used medical care. The propensity of these patients to distort reality was observed to interfere with the usefulness of sonography...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1984-07-01 00:00:00
abstract：:The efficacy of a two-dose perioperative course of oral metronidazole or suction drainage of the vaginal vault was evaluated in a randomized study of 150 patients undergoing abdominal hysterectomy. Patients receiving metronidazole demonstrated a significant reduction in febrile morbidity (from 48 to 8%), infectious mo...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1984-03-01 00:00:00
abstract：OBJECTIVE:To determine whether gravidas with prior low vertical uterine incision(s) are at a higher risk for uterine rupture during a trial of labor after cesarean delivery than women with prior low transverse uterine incision(s). METHODS:The medical records of women undergoing a trial of labor after prior cesarean de...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(99)00398-1
更新日期：1999-11-01 00:00:00
abstract：:Thirty-six women, treated with radical hysterectomy (Piver types III-IV) plus systematic para-aortic and pelvic lymphadenectomy for cervical carcinoma, underwent serial postoperative ultrasound examinations to determine the incidence of lymphocele and the therapeutic efficacy of percutaneous catheter drainage. Pelvic ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1990-08-01 00:00:00
abstract：OBJECTIVE:To evaluate the power transmission, spot size, power density, and energy density of a new isotopic carbon dioxide (13CO2) laser compared with a conventional CO2 laser. METHODS:Experiments were performed in a laboratory using a conventional CO2 laser and an isotopic 13CO2 laser. Two laparoscopes with 5-mm and...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1994-05-01 00:00:00
abstract：OBJECTIVE:The relationship between the specialized nurses of the Labor and Delivery Suite and the medical students who are rotating through the unit as clinical clerks has traditionally been a poor one. The objective of this project was to develop a program which pairs medical students with nurse preceptors to improve ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000223202.04393.2a
更新日期：2006-07-01 00:00:00
abstract：:In order to evaluate the most reliable means of determining fetal maturity, six amniotic fluid components were analyzed from 99 women who were 22 to 40 weeks pregnant. The six parameters investigated were: amylase activity the lecithin to sphingomyelin (L/S) ratio, percentage of fat cells, and the concentrations of pr...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/00006250-197507000-00014
更新日期：1975-07-01 00:00:00
abstract：OBJECTIVE:To evaluate weekly stripping of membranes at term to determine its safety and effectiveness in reducing the incidence of prolonged and postterm pregnancies. METHODS:One hundred forty-two pregnant women with certain gestational dates were randomly selected to receive, starting at 38 weeks, either weekly strip...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/0029-7844(96)00046-4
更新日期：1996-06-01 00:00:00
abstract：OBJECTIVE:To estimate the influence of adequacy of prenatal care and other known risk factors on the risk of repeating low birth weight (LBW) (less than 2500 g). METHODS:This was a retrospective cohort study of women having two births in Washington state during 1984-1990, as recorded using linked birth certificate rec...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1994-10-01 00:00:00
abstract：:The effects of repeated freezing and thawing. on certain properties of early gestation amniotic fluid were studied. Six anmiotic fluids from 15- to 17-week gestations were investigated. Total protein determinations revealed that there was no significant loss of total protein with rapid freezing and thawing up to 10 ti...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1975-09-01 00:00:00
abstract：BACKGROUND:Adult females with menorrhagia may have unrecognized mild von Willebrand's disease. Most females with known von Willebrand's disease report menorrhagia. CASE:A 38-year-old healthy female desired contraception. She described heavy menses lasting 8 days since menarche. History included uncomplicated vaginal d...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/01.AOG.0000157758.94890.59
更新日期：2005-05-01 00:00:00
abstract：OBJECTIVE:To correlate neonatal and infant clinical outcome with parasite load in amniotic fluid (AF). METHODS:We conducted a retrospective cohort study of 122 children whose mothers had toxoplasmosis during pregnancy. The children were monitored from birth to 12 months old. Stored AF samples were obtained at maternal...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000002131
更新日期：2017-08-01 00:00:00
abstract：:Maternal serum levels of placental protein 5 (PP5) were measured during the third trimester in women with normal and abnormal pregnancies. PP5 levels were significantly elevated in patients with preeclampsia, diabetes, intrauterine growth retardation associated with preeclampsia, and twin pregnancy. ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1982-04-01 00:00:00
abstract：:Eighty-eight cases of Stage I and Stage II carcinoma of the cervix treated with radiotherapy at the University of North Carolina Memorial Hospital between April 1969 and July 1971 are reviewed. The question of whether the radiation time-dose-fraction relationship can be applied to the combination of external beam and ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1975-10-01 00:00:00
abstract：BACKGROUND:Monoamniotic twins with ultrasonographic evidence of umbilical cord entanglement present a management challenge in the antepartum period. CASES:We report two pregnancies with monoamniotic twins and ultrasonographic evidence of cord entanglement in which longitudinal Doppler flow velocity waveforms of the um...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/0029-7844(95)00210-i
更新日期：1995-10-01 00:00:00
abstract：OBJECTIVE:To determine the safety, tolerability, and efficacy of combination gefitinib and methotrexate to treat ectopic pregnancy. METHODS:We performed a phase I, single-arm (nonrandomized), open-label study. Twelve women with ectopic pregnancies were administered methotrexate (50 mg/m, intramuscular) and 250 mg oral...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0b013e3182a14cfb
更新日期：2013-10-01 00:00:00
abstract：:Two hundred thirteen women with abnormal glucose tolerance tests (GTTs) were diagnosed over 9 years by a screening program involving the total antenatal population. Each subject was matched for age, parity, and ethnic group with a control. The gestational diabetics were subdivided into classes A1 or A2 based on the fa...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1989-09-01 00:00:00
abstract：BACKGROUND:Spectral Doppler ultrasound, an important diagnostic tool for the functional assessment of various organs, as yet has no major use in prenatal diagnosis due to the conventional technique's limitation of analyzing only one site at a time. Our aim was to develop a new modality that shows simultaneous studies o...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章
doi：
更新日期：1998-08-01 00:00:00
abstract：OBJECTIVE:To determine the factors that influence the survival of patients with endometrial carcinoma histologically confined to the uterus. METHODS:Retrospective analysis was conducted of 262 surgically staged cases using multiple regression (Cox proportional hazards model). RESULTS:After excluding patients with cle...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-10-01 00:00:00
abstract：:A 19-year-old primigravida at term presented with bilateral, spontaneous pneumothorax. The maternal and infant outcomes were successful. The impact on pregnancy is discussed, and suggestions are made for obstetric management. ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1983-09-01 00:00:00
abstract：:A case of twin pregnancy with a fetus in each horn of a uterus didelphys is reported. During labor that resulted in the term birth of 1 fetus, contractions occurred temporarily in the other horn and subsided 2 hours after delivery. ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1983-01-01 00:00:00
abstract：BACKGROUND:Placental site trophoblastic tumor is a rare subtype of gestational trophoblastic neoplasia affecting women of reproductive age. The preferred method of treatment is surgical resection. CASE:A 33-year-old woman, gravida 3 para 1111, was incidentally diagnosed with placental site trophoblastic tumor during a...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/aog.0b013e31826d7da6
更新日期：2013-02-01 00:00:00
abstract：OBJECTIVE:Visual estimation of blood loss is often inaccurate and imprecise. Obstetric bleeding requires expedient identification and intervention to prevent maternal morbidity and mortality. We aimed to create a visual aid to improve accuracy of estimated obstetric blood loss. METHODS:We designed a pocket card contai...
journal_title：Obstetrics and gynecology
pub_type： 临床试验,杂志文章
doi：10.1097/AOG.0000000000000233
更新日期：2014-05-01 00:00:00
abstract：:The association between low Apgar scores (7 or less) at 1 and 5 minutes and cognitive performance in late adolescence was assessed. A 17-year follow-up of 1942 subjects was performed. The intelligence test scores at 17 years of age were matched with 1- and 5-minutes Apgar scores. A multiple linear regression analysis ...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1991-06-01 00:00:00
abstract：:Blood coagulation and fibrinolytic inhibitors and the balance between and within the two systems were investigated in 26 normal pregnant women during pregnancy and the puerperium. The concentration of the coagulation inhibitors antithrombin and protein C remained within normal levels, whereas the mean level of free pr...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1992-07-01 00:00:00
abstract：OBJECTIVE:To assess the effect of maternal involvement in motor vehicle crashes on the likelihood of adverse pregnancy outcomes and to estimate the effect of seatbelt use in reducing the occurrence of those outcomes. METHODS:Statewide motor vehicle crash, birth, and fetal death records from 1992 to 1999 were probabili...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1016/s0029-7844(03)00518-0
更新日期：2003-08-01 00:00:00
abstract：INTRODUCTION:The first transdermal drug delivery system was introduced in the United States over 20 years ago. Created as an alternative route of administration to improve patient compliance as well as to reduce side effects, the transdermal delivery of drugs now represents a $1.5 to $2 billion market and is growing ra...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章,评审
doi：10.1097/01.AOG.0000161958.70059.db
更新日期：2005-05-01 00:00:00
abstract：OBJECTIVE:To compare the odds of a good perinatal outcome between cryopreserved and fresh donor oocytes. METHODS:We used the Society for Assisted Reproductive Technology Clinic Outcomes Reporting System to conduct a retrospective cohort study of women undergoing donor oocyte in vitro fertilization (IVF) from 2012 to 2...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000003695
更新日期：2020-03-01 00:00:00
abstract：:Preterm birth is the leading cause of neonatal mortality and the most common reason for antenatal hospitalization (1-4). In the United States, approximately 12% of all live births occur before term, and preterm labor preceded approximately 50% of these preterm births (5, 6). Although the causes of preterm labor are no...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：10.1097/AOG.0000000000001260
更新日期：2016-01-01 00:00:00
abstract：:Two patients with sickle-delta gamma thalassemia are reported who experienced the typical complications of sickling disorders in the last 2 months of 4 pregnancies. The diagnosis, genetics, and management of pregnancy in this rare hematologic disease, which causes minimal morbidity in the nonpregnant woman, are discus...
journal_title：Obstetrics and gynecology
pub_type： 杂志文章
doi：
更新日期：1981-07-01 00:00:00
