von Willebrand's disease diagnosed after menorrhagia worsened from levonorgestrel intrauterine system.

Abstract:

BACKGROUND:Adult females with menorrhagia may have unrecognized mild von Willebrand's disease. Most females with known von Willebrand's disease report menorrhagia. CASE:A 38-year-old healthy female desired contraception. She described heavy menses lasting 8 days since menarche. History included uncomplicated vaginal deliveries. Physical examination was normal. The levonorgestrel intrauterine system was placed. Her menorrhagia then worsened to 14 successive days each month. Evaluation revealed mild von Willebrand's disease. At 19 months of follow-up, she retained her levonorgestrel intrauterine system and avoided pregnancy. Her menses slowly improved to spotting for 8 days each month. CONCLUSION:Von Willebrand's disease is a likely cause of menorrhagia that goes unrecognized as well as a potential cause for "failed" conservative treatment for menorrhagia. Understanding the cause of menorrhagia is an important aspect of evaluating this common symptom.

journal_name

Obstet Gynecol

authors

Lukes AS,Perry S,Ortel TL

doi

10.1097/01.AOG.0000157758.94890.59

subject

Has Abstract

pub_date

2005-05-01 00:00:00

pages

1223-6

issue

5 Pt 2

eissn

0029-7844

issn

1873-233X

pii

105/5/1223

journal_volume

105

pub_type

杂志文章
  • Longitudinal analysis of a multisite clerkship.

    abstract::Monitoring the quality of well-established multisite clerkships can be aided by the use of trend analysis and graphic-oriented presentations. Five years of data on student performance, experience, and perceptions are reported for an obstetrics and gynecology clerkship offered at eight geographically dispersed sites. O...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Strand DA,Vontver LA,Stenchever MA,Hadac RR,Irby DM

    更新日期:1985-11-01 00:00:00

  • A prospective comparison of hourly and quarter-hourly oxytocin dose increase intervals for the induction of labor at term.

    abstract::Fifty-two women undergoing labor induction and vaginal delivery at term were randomized between two oxytocin infusion protocols, involving hourly versus quarter-hourly increases in dose. Potential differences were sought of duration of labor, amount of uterine activity generated, and amount of oxytocin required. Start...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Blakemore KJ,Qin NG,Petrie RH,Paine LL

    更新日期:1990-05-01 00:00:00

  • Risk of Peripartum Hysterectomy and Center Hysterectomy and Delivery Volume.

    abstract:OBJECTIVE:To characterize where women at risk for and undergoing peripartum hysterectomy delivered in terms of obstetric volume and procedural experience. METHODS:We used data from the Perspective database to retrospectively evaluate trends in peripartum hysterectomy and deliveries at high risk of peripartum hysterect...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000001722

    authors: Govindappagari S,Wright JD,Ananth CV,Huang Y,DʼAlton ME,Friedman AM

    更新日期:2016-12-01 00:00:00

  • CA 125 serum levels correlated with second-look operations among ovarian cancer patients.

    abstract::CA 125, which is an antigenic determinant expressed by many epithelial ovarian cancers, is measured in serum using a solid phase immunoradiometric assay. Sera from 55 patients who were in clinical remission and underwent a second-look operation to assess disease status after chemotherapy were studied prospectively. Al...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/00006250-198605000-00016

    authors: Berek JS,Knapp RC,Malkasian GD,Lavin PT,Whitney C,Niloff JM,Bast RC Jr

    更新日期:1986-05-01 00:00:00

  • Committee opinion no 611: method for estimating due date.

    abstract::: Accurate dating of pregnancy is important to improve outcomes and is a research and public health imperative. As soon as data from the last menstrual period, the first accurate ultrasound examination, or both are obtained, the gestational age and the estimated due date should be determined, discussed with the patien...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,评审

    doi:10.1097/01.AOG.0000454932.15177.be

    authors:

    更新日期:2014-10-01 00:00:00

  • Biparietal diameter/femur length ratio, cephalic index, and femur length measurements: not reliable screening techniques for Down syndrome.

    abstract::Previous published reports have shown that fetuses affected with Down syndrome have normal biparietal diameter (BPD), high BPD-to-femur length ratio, and shorter femur length and occipitofrontal diameter. A retrospective comparison of the BPD, occipitofrontal diameter, cephalic index, femur length, and BPD/femur lengt...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Shah YG,Eckl CJ,Stinson SK,Woods JR Jr

    更新日期:1990-02-01 00:00:00

  • Porcine subintestinal submucosal graft augmentation for rectocele repair: a randomized controlled trial.

    abstract:OBJECTIVE:To estimate the effect of porcine subintestinal submucosal graft augmentation on improving anatomic and subjective rectocele repair outcomes compared with native tissue repair. METHODS:We conducted a randomized controlled trial at two sites, including women with at least stage 2 symptomatic rectocele. Anatom...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1097/AOG.0b013e31823d407e

    authors: Sung VW,Rardin CR,Raker CA,Lasala CA,Myers DL

    更新日期:2012-01-01 00:00:00

  • The association between persistent occiput posterior position and neonatal outcomes.

    abstract:OBJECTIVE:To examine the effect of persistent occiput posterior position on neonatal outcome. METHODS:This is a retrospective cohort study of 31,392 term, cephalic, singleton births. Women with neonates born in persistent occiput posterior position at delivery were compared to those with occiput anterior position. Wom...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000206217.07883.a2

    authors: Cheng YW,Shaffer BL,Caughey AB

    更新日期:2006-04-01 00:00:00

  • Intrapartum fetal cardiac arrhythmias.

    abstract::Fifteen cases of fetal cardiac arrhythmia were detected by direct fetal electrocardiogram (FECG) during intrapartum fetal monitoring. The frequency of arrhythmia of 12.4/1000 monitored births. Thirteen of the arrhythmias were supraventricular. Atrial bigeminy was the most commonly observed arrhythmia, followed by atri...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Young BK,Katz M,Klein SA

    更新日期:1979-10-01 00:00:00

  • Unconjugated estriol and cortisol in maternal and cord serum and amniotic fluid in normal and abnormal pregnancy.

    abstract::This study investigated unconjugated E3 and cortisol in normal and abnormal (diabetes and chronic stress) pregnancies and the compartmental (maternal, fetoplacental, amniotic fluid) concentrations and relationships in simultaneous samples. It was demonstrated that in labor both steriods are higher in all compartments ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Goldkrand JW

    更新日期:1978-09-01 00:00:00

  • Development of a nomogram for prediction of vaginal birth after cesarean delivery.

    abstract:OBJECTIVE:To develop a model based on factors available at the first prenatal visit that predicts chance of successful vaginal birth after cesarean delivery (VBAC) for individual patients who undergo a trial of labor. METHODS:All women with one prior low transverse cesarean who underwent a trial of labor at term with ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,多中心研究

    doi:10.1097/01.AOG.0000259312.36053.02

    authors: Grobman WA,Lai Y,Landon MB,Spong CY,Leveno KJ,Rouse DJ,Varner MW,Moawad AH,Caritis SN,Harper M,Wapner RJ,Sorokin Y,Miodovnik M,Carpenter M,O'Sullivan MJ,Sibai BM,Langer O,Thorp JM,Ramin SM,Mercer BM,National Insti

    更新日期:2007-04-01 00:00:00

  • Late meconium passage in labor--a sign of fetal distress?

    abstract::Although the passage early in labor of thick amniotic fluid heavily stained with meconium is recognized as an indication of potential fetal asphyxia, the significance of late passage of meconium-stained fluid in labor is less certain. One hundren twenty-eight patients with late passage of meconium in labor and 134 con...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Meis PJ,Hobel CJ,Ureda JR

    更新日期:1982-03-01 00:00:00

  • The use of quinidine sulfate throughout pregnancy.

    abstract::A gravid patient was given quinidine sulfate for idiopathic ventricular tachycardia. The serum levels of quinidine remained stable throughout pregnancy. At delivery, maternal and neonatal quinidine levels were equivalent, while the level in the amniotic fluid was significantly elevated. Explanations for the latter inc...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Hill LM,Malkasian GD Jr

    更新日期:1979-09-01 00:00:00

  • Combining vaginal ultrasonography and office endometrial sampling in the diagnosis of endometrial disease in postmenopausal women.

    abstract:OBJECTIVE:To investigate the value of the combined use of vaginal ultrasonography and endometrial sampling in the office for the diagnosis of endometrial disease in postmenopausal women. METHODS:One hundred forty consecutive postmenopausal women presenting with uterine bleeding or endometrial cells on cervical cytolog...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章

    doi:10.1016/0029-7844(94)00421-9

    authors: Van den Bosch T,Vandendael A,Van Schoubroeck D,Wranz PA,Lombard CJ

    更新日期:1995-03-01 00:00:00

  • Fetal cardiovascular responses to distress. A review.

    abstract::This review is designed to provide a broad view of fetal cardiovascular response to fetal distress. The presentation focuses on data obtained from laboratories working with fetal sheep, or occasionally fetal monkeys, instead of attempting to interpret data resulting from human fetal studies. Human fetal studies are un...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Goodlin RC

    更新日期:1977-03-01 00:00:00

  • Maximal exercise testing in late gestation: fetal responses.

    abstract:OBJECTIVE:To determine the fetal response to and safety of maximal maternal exercise in the third trimester. METHODS:Twenty-three active women with uncomplicated pregnancies (singleton gestations) underwent maximal exercise testing in late gestation using a progressive maximal cycle ergometer protocol. Fetal heart rat...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1016/s0029-7844(00)00940-6

    authors: MacPhail A,Davies GA,Victory R,Wolfe LA

    更新日期:2000-10-01 00:00:00

  • Committee Opinion No. 680 Summary: The Use and Development of Checklists in Obstetrics and Gynecology.

    abstract::Checklists are used in medical and nonmedical settings as cognitive aids to ensure that users complete all the items associated with a particular task. They are ideal for tasks with many steps, for tasks performed under stressful circumstances, or for reminding people to perform tasks that they are not routinely accus...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000001766

    authors:

    更新日期:2016-11-01 00:00:00

  • Clinical use of immunoperoxidase markers in excluding ectopic gestation.

    abstract::Ectopic pregnancy is suspected when a pregnancy test is positive and an Arias-Stella phenomenon with decidua is seen on endometrial curettings in the absence of chorionic villi and trophoblast. We performed immunoperoxidase stains for beta-hCG, hPL, placental alkaline phosphatase, and keratin (AE1/AE3) on endometrial ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Kaspar HG,To T,Dinh TV

    更新日期:1991-09-01 00:00:00

  • Trends and Predictors of Cerclage Use in the United States From 2005 to 2012.

    abstract:OBJECTIVE:To characterize the use of cervical cerclage on a population basis. METHODS:This population-based study of U.S. natality records from 2005 to 2012 evaluated use of cerclage in singleton and multiple gestation live births. Obstetric, medical, and demographic characteristics were evaluated. A multivariable log...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000000930

    authors: Friedman AM,Ananth CV,Siddiq Z,D'Alton ME,Wright JD

    更新日期:2015-08-01 00:00:00

  • Prognostic importance of intraoperative rupture of malignant ovarian epithelial neoplasms.

    abstract:OBJECTIVE:To determine whether rupture of malignant ovarian epithelial tumors at the time of operation influences the patient's overall prognosis. METHODS:Between 1975 and 1990, 79 patients with stage I invasive epithelial ovarian cancer were treated at Massachusetts General Hospital. Patients were identified from the...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Sainz de la Cuesta R,Goff BA,Fuller AF Jr,Nikrui N,Eichhorn JH,Rice LW

    更新日期:1994-07-01 00:00:00

  • Use of recombinant activated factor VII in primary postpartum hemorrhage: the Northern European registry 2000-2004.

    abstract:OBJECTIVE:To collect data from nine European countries for cases of obstetric hemorrhage between 2000 and 2004 in which recombinant activated factor VII (rFVIIa) was used. METHODS:The cases were identified through national surveys. Standardized case report forms included sociodemographic details, past medical and obst...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000288515.48066.99

    authors: Alfirevic Z,Elbourne D,Pavord S,Bolte A,Van Geijn H,Mercier F,Ahonen J,Bremme K,Bødker B,Magnúsdóttir EM,Salvesen K,Prendiville W,Truesdale A,Clemens F,Piercy D,Gyte G

    更新日期:2007-12-01 00:00:00

  • Extent of surgery for pelvic inflammatory disease in relation to duration of intrauterine device use.

    abstract::The risk of a first episode of pelvic inflammatory disease resulting in extensive surgery was examined in relation to duration of intrauterine device (IUD) use in a case-control study. Extensive surgery for pelvic inflammatory disease was defined as hysterectomy or bilateral adenexal surgery, with pelvic inflammatory ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Stadel BV,Schlesselman S

    更新日期:1984-02-01 00:00:00

  • Pathophysiologic Origins of Brachial Plexus Injury.

    abstract:OBJECTIVE:To analyze the origins and consequences of cases of brachial plexus injuries and their relationship to shoulder dystocia. METHODS:We conducted a retrospective cohort study and identified all neonates with brachial plexus injury delivered at our institution between March 2012 and July 2019. A review was perfo...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000004013

    authors: Johnson GJ,Denning S,Clark SL,Davidson C

    更新日期:2020-10-01 00:00:00

  • The secretion of insulin-like growth factors I and II by explant cultures of fibroids and myometrium from women treated with a gonadotropin-releasing hormone agonist.

    abstract::The gonadotropin-releasing hormone agonist (GnRH-a) leuprolide acetate depot was used as a biologic probe to investigate the possible roles of insulin-like growth factors (IGFs) I and II in fibroid growth. The secretion of IGF-I and IGF-II by explant cultures of fibroids and myometria from women treated with a GnRH-a ...

    journal_title:Obstetrics and gynecology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Rein MS,Friedman AJ,Pandian MR,Heffner LJ

    更新日期:1990-09-01 00:00:00

  • Diagnostic accuracy of fetal heart rate monitoring in the identification of neonatal encephalopathy.

    abstract:OBJECTIVE:To estimate the diagnostic accuracy of electronic fetal heart rate abnormalities in the identification of neonates with encephalopathy treated with whole-body hypothermia. METHODS:Between January 1, 2007, and July 1, 2013, there were 39 neonates born at two hospitals within our system treated with whole-body...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/AOG.0000000000000424

    authors: Graham EM,Adami RR,McKenney SL,Jennings JM,Burd I,Witter FR

    更新日期:2014-09-01 00:00:00

  • Serial membrane sweeping at term in planned vaginal birth after cesarean: a randomized controlled trial.

    abstract:OBJECTIVE:To estimate the effect of serial membrane sweeping on the onset of labor in women who planned vaginal birth after cesarean (VBAC). METHODS:Women at term with one transverse lower segment cesarean delivery who were suitable for and who planned VBAC were approached to participate. Participants were randomly as...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/AOG.0b013e3181b8fa00

    authors: Hamdan M,Sidhu K,Sabir N,Omar SZ,Tan PC

    更新日期:2009-10-01 00:00:00

  • Immunologic detection of condylomata acuminata-specific antigens.

    abstract::A rabbit serum fraction was prepared which contained antibody specific for unique antigen(s) found in human condylomata acuminata tissue but not in other human papillomatous or normal tissues. Indirect immunofluorescent staining of cryostat sections of human tissues demonstrated an intense nuclear fluorescence in cell...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Dunn J,Weinstein L,Droegemueller W,Meinke W

    更新日期:1981-03-01 00:00:00

  • Pregnancy outcome after intra-abdominal bleeding due to placenta percreta at 14 weeks of gestation.

    abstract:BACKGROUND:With the rising rate of cesarean deliveries, the rate of placenta previa and placenta percreta will rise concomitantly resulting in a greater incidence of severe complications. CASE:This case report describes a pregnancy with a massive intra-abdominal bleeding due to placenta percreta at 14 weeks of gestati...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/01.AOG.0000254168.73160.21

    authors: Roeters AE,Oudijk MA,Heydanus R,Bruinse HW

    更新日期:2007-02-01 00:00:00

  • Abdominopelvic computed tomography: evaluation in patients undergoing second-look laparotomy for ovarian carcinoma.

    abstract::Preoperative abdominopelvic computed tomography results and operative findings were compared in 52 patients undergoing second-look laparotomy to confirm tumor status. Seventeen true-negative, 22 false-negative, and 13 true-positive scans were found. The sensitivity was 0.38, specificity was 1.0, and diagnostic accurac...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:

    authors: Brenner DE,Shaff MI,Jones HW,Grosh WW,Greco FA,Burnett LS

    更新日期:1985-05-01 00:00:00

  • Deaths from ectopic pregnancy, United States, 1979 to 1980.

    abstract::During the 1970s in the United States, the number of hospitalizations for ectopic pregnancy increased more than twofold, and ectopic pregnancy emerged as a leading cause of maternal mortality. All known deaths from ectopic pregnancy in the United States from January 1, 1979, to December 31, 1980, were investigated by ...

    journal_title:Obstetrics and gynecology

    pub_type: 杂志文章

    doi:10.1097/00006250-198309000-00014

    authors: Dorfman SF

    更新日期:1983-09-01 00:00:00