Abstract：
:Screening with portable echocardiography has uncovered a large burden of latent rheumatic heart disease (RHD) among asymptomatic children in endemic regions, the significance of which remains unclear. This study aimed to determine the 2-year outcomes for children with latent RHD diagnosed by echocardiographic screening. Children identified with latent RHD enrolled in a biannual follow-up program. Risk factors for disease persistence and progression were examined. Of 62 children, 51 (82 %) with latent RHD had a median follow-up period of 25 months. Of these 51 children, 17 (33.3 %) reported an interval sore throat or symptoms consistent with acute rheumatic fever (ARF). Of 43 children initially classified as having borderline RHD, 21 (49 %) remained stable, 18 (42 %) improved (to no RHD) and 4 (10 %) worsened to definite RHD. Of the 8 children initially classified as having definite RHD, 6 (75 %) remained stable, and 2 (25 %) improved to borderline RHD. Two children had confirmed episodes of recurrent ARF, one of which represented the sole case of clinical worsening. The risk factors for disease persistence or progression included younger age (p = 0.05), higher antistreptolysin O titers at diagnosis (p = 0.05), and more morphologic valve abnormalities (p = 0.01). After 2 years, most of the children had a benign course, with 91 % remaining stable or showing improvement. Education may improve recognition of streptococcal sore throat. Longer-term follow-up evaluation, however, is warranted to confirm disease progression and risk factor profile. This could help tailor screening protocols for those at highest risk.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Beaton A,Okello E,Aliku T,Lubega S,Lwabi P,Mondo C,McCarter R,Sable Cdoi
10.1007/s00246-014-0925-3subject
Has Abstractpub_date
2014-10-01 00:00:00pages
1259-67issue
7eissn
0172-0643issn
1432-1971journal_volume
35pub_type
杂志文章abstract：:In August 2010, the Nit-Occlud® Lê (EUREVECO) became available for transcatheter coil occlusion of ventricular septal defects (VSDs). Retrospective European Registry for VSD Closure using the Nit-Occlud® Lê-VSD-Coil; analysis of the feasibility, results, safety and follow-up of VSD-closure over a 3-year period in 18 E...
journal_title：Pediatric cardiology
pub_type： 杂志文章,多中心研究
doi：10.1007/s00246-016-1502-8
更新日期：2017-02-01 00:00:00
abstract：:Routine use of intraoperative transesophageal echocardiography (TEE) is a safe monitoring and diagnostic method during pediatric congenital cardiac surgery. However, the question of whether intraoperative TEE is accurate and cost effective for patients with tetralogy of Fallot (TOF) has not been raised. This study aim...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0423-4
更新日期：2013-02-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002460010254
更新日期：2001-09-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-020-02295-1
更新日期：2020-03-01 00:00:00
abstract：:The Norwood procedure with a modified Blalock-Taussig shunt (MBTS) is the first of the three-stage surgical palliation for infants with hypoplastic left heart syndrome. We report a patient with schistocytic hemolytic anemia that developed following a right MBTS with a Gore-Tex graft. Hemolysis associated with a MBTS h...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-006-1410-4
更新日期：2007-05-01 00:00:00
abstract：:Operative survival after the Norwood procedure has significantly improved during the past 10 years. However, there remains attrition among Norwood survivors before reaching planned second-stage palliation. The purpose of this study was to evaluate potential risk factors for interstage mortality among Norwood survivors...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-004-0776-4
更新日期：2005-07-01 00:00:00
abstract：:This study was undertaken to examine the impact that prenatal diagnosis of congenital heart disease (CHD) has on birth and early neonatal outcomes. The prevalence of prenatally diagnosed CHD has risen over the past decade, but the effect that prenatal diagnosis of CHD has on peripartum decisions remains unclear. No co...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0504-4
更新日期：2013-03-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0462-x
更新日期：2013-02-01 00:00:00
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journal_title：Pediatric cardiology
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900072
更新日期：1996-09-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-011-0049-y
更新日期：2012-01-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-014-0929-z
更新日期：2014-10-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-005-0920-9
更新日期：2005-11-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-012-0351-3
更新日期：2012-12-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002469900430
更新日期：1999-03-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-006-0169-y
更新日期：2007-07-01 00:00:00
abstract：:Right-ventricular diverticula (RVD), although rare, have particular characteristics. Our study describes the morphology of anterosuperior diverticula of the right ventricle (RV) and patient outcome for this anomaly. Retrospective analysis was performed on all patients with anterosuperior RVD diagnosed in two tertiary ...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-014-0885-7
更新日期：2014-08-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00246-018-1816-9
更新日期：2018-03-01 00:00:00
abstract：:The original version of the article unfortunately contained an alignment error in Table 1. The correct version of Table 1 is given below. ...
journal_title：Pediatric cardiology
pub_type： 杂志文章,已发布勘误
doi：10.1007/s00246-018-1978-5
更新日期：2019-01-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-016-1456-x
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF02263445
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-010-9739-0
更新日期：2010-10-01 00:00:00
abstract：:A fetal echocardiographic scan was performed when routine prenatal ultrasound screening failed to identify four cardiac chambers. The scan showed a single ventricle with an associated circoid varicosity. Because of these anomalies, amniocentesis was suggested and trisomy 18 confirmed. The presence of major cardiac str...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/BF00794843
更新日期：1993-01-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s002460010202
更新日期：2001-05-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-003-0567-3
更新日期：2004-09-01 00:00:00
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journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-020-02381-4
更新日期：2020-10-01 00:00:00
abstract：:Branch pulmonary artery stenosis (BPAS) in the setting of systemic-pulmonary artery shunts (SPS) may result in significant sequelae. Limited information exists regarding the safety and efficacy of pulmonary artery balloon angioplasty and stent implantation via SPS in neonates and infants. This study aimed to examine t...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-013-0657-9
更新日期：2013-08-01 00:00:00
abstract：:Although Kawasaki disease (KD) was first discovered and identified in Japan by Kawasaki in the 1960s, fatal KD cases resulting from coronary artery aneurysms had been identified retrospectively in the West as early as 1871. Kawasaki initially postulated that this disease was a new, as yet unidentified, self-limiting i...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-009-9625-9
更新日期：2010-05-01 00:00:00
abstract：:Hyperplastic left heart syndrome (HLHS) patients are palliated by creating a Fontan-type circulation passing from different surgical stages. The aim of this work is to describe the evolution of ventricular energetics parameters in HLHS patients during the different stages of palliation including the hybrid, the Norwoo...
journal_title：Pediatric cardiology
pub_type： 杂志文章
doi：10.1007/s00246-017-1704-8
更新日期：2017-12-01 00:00:00
abstract：:Dilated cardiomyopathy in children still has a poor prognosis with high rates of mortality and cardiac transplantation (resp. around 20 and 25%). Awaiting transplantation or possible recovery, these pediatric patients are mechanically supported with extracorporeal membrane oxygenation or a paracorporeal ventricular as...
journal_title：Pediatric cardiology
pub_type： 杂志文章,评审
doi：10.1007/s00246-017-1610-0
更新日期：2017-06-01 00:00:00
