Prenatal diagnosis of congenital heart disease and birth outcomes.

abstract：:Embryonic development is a tightly regulated process, and many families of genes functions to provide a regulatory genetic network to achieve such a program. The homeobox genes are an extensive family that encodes transcription factors with a characteristic 60-amino acid homeodomain. Mutations in these genes or in the...

journal_title：Pediatric cardiology

authors： Liu H,Espinoza-Lewis RA,Chen C,Hu X,Zhang Y,Chen Y

更新日期：2012-08-01 00:00:00

abstract：:Percutaneous balloon aortic valvuloplasty was attempted in an eight-month-old infant with severe aortic valve stenosis. The procedure resulted in a fall in the resting transvalvular systolic pressure gradient from 106 mmHg to 40 mmHg and no aortic regurgitation. Clinical and Doppler echocardiography findings suggest p...

journal_title：Pediatric cardiology

authors： Sánchez GR,Mehta AV,Ewing LL,Brickley SE,Anderson TM,Black IF

更新日期：1985-01-01 00:00:00

abstract：:We report our experience with asymptomatic valvar aortic stenosis diagnosed during infancy. During the period between November 1, 1986 and October 31, 1992 a total of 13 infants were diagnosed with asymptomatic aortic stenosis, 5 of whom showed rapid progression over the first 2 years of life. Two of these asymptomati...

journal_title：Pediatric cardiology

authors： Anand R,Mehta AV

更新日期：1997-01-01 00:00:00

abstract：:Heart failure (HF) has high morbidity and mortality in children. This study aimed to investigate the value of cardiac myosin binding protein-C (cMyBP-C) as a diagnostic and prognostic biomarker in children with heart failure. This study was a prospective case-control study that involved 50 children with acute HF and 2...

journal_title：Pediatric cardiology

authors： El Amrousy D,Hodeib H,Suliman G,Hablas N,Salama ER,Esam A

更新日期：2017-02-01 00:00:00

abstract：:Fluid overload and prolonged mechanical ventilation lead to worse outcomes in critically ill children. However, the association between these variables in children following congenital heart surgery is unknown. The objectives of this study were to describe the association between fluid overload and duration of mechani...

journal_title：Pediatric cardiology

authors： Sampaio TZ,O'Hearn K,Reddy D,Menon K

更新日期：2015-12-01 00:00:00

abstract：:Overweight and obesity rates have risen dramatically in the United States, with subsequent detrimental comorbidity risks. The rates for obesity among children with congenital and acquired heart disease have rarely been reported. A retrospective cross-sectional study was conducted to determine the prevalence of overwei...

journal_title：Pediatric cardiology

authors： Shustak RJ,McGuire SB,October TW,Phoon CK,Chun AJ

更新日期：2012-01-01 00:00:00

abstract：:Sedation/anesthesia is critical to cardiac catheterization in the pediatric/congenital heart patient. We sought to identify current sedation/anesthesia practices, the serious adverse event rate related to airway, sedation, or anesthesia, and the rate of intra-procedural conversion from procedural sedation to the use o...

journal_title：Pediatric cardiology

authors： Lin CH,Desai S,Nicolas R,Gauvreau K,Foerster S,Sharma A,Armsby L,Marshall AC,Odegard K,DiNardo J,Vincent J,El-Said H,Spaeth J,Goldstein B,Holzer R,Kreutzer J,Balzer D,Bergersen L

更新日期：2015-10-01 00:00:00

abstract：:Noonan syndrome is an autosomal dominant disease that manifests a wide variety of clinical characteristics. The syndrome is also associated with some cardiac defects. Half of all Noonan syndrome cases are caused by mutations in the PTPN11 gene, but only limited data are available regarding aortic involvement in these ...

journal_title：Pediatric cardiology

authors： Jefferies JL,Belmont JW,Pignatelli R,Towbin JA,Craigen WJ

更新日期：2010-01-01 00:00:00

abstract：:We sought to document morbidities and growth for patients with hypoplastic left heart syndrome (HLHS) to inform the initial surgical decision and understand healthcare needs. Data were obtained on 137 patients with HLHS, born between 1989 and 1994, who survived staged surgery ( n = 62) or transplantation ( n = 75) and...

journal_title：Pediatric cardiology

authors： Jenkins PC,Flanagan MF,Jenkins KJ,Sargent JD,Canter CE,Chinnock RE,Vincent RN,O'Connor GT

更新日期：2004-01-01 00:00:00

abstract：:The COVID-19 pandemic has had devastating direct consequences on the health of affected patients. It has also had a significant impact on the ability of unaffected children to be physically active. We evaluated the effect of deconditioning from social distancing and school shutdowns implemented during the COVID-19 pan...

journal_title：Pediatric cardiology

authors： Dayton JD,Ford K,Carroll SJ,Flynn PA,Kourtidou S,Holzer RJ

更新日期：2021-01-04 00:00:00

abstract：:The HOXA1 gene plays a fundamental role in embryonic morphogenesis. Recent studies in humans and mice have indicated that HOXA1 plays a previously unrecognized role in cardiovascular system development. Congenital heart disease (CHD), particularly ventricular septal defect (VSD), might be a clinically isolated manifes...

journal_title：Pediatric cardiology

authors： Liu J,Wang B,Chen X,Li H,Wang J,Cheng L,Ma X,Gao B

更新日期：2013-02-01 00:00:00

abstract：:A case of aneurysmal enlargement of the right atrium was found accidentally during a routine examination. The patient was asymptomatic and free of palpitations or proven rhythm disturbances. The results of echocardiography, magnetic resonance imaging, and cardiac catheterization excluded cardiac malformation, which co...

journal_title：Pediatric cardiology

authors： Kozelj M,Angelski R,Pavcnik D,Zorman D

更新日期：1998-09-01 00:00:00

abstract：:This study aimed to determine the dimensions of the thoracic aorta and the predictors of aortic dimensions in girls and young women with Turner syndrome (TS). A cross-sectional study was performed at a secondary care center. The study compared 41 TS patients with 50 healthy age-matched control subjects. The mean age o...

journal_title：Pediatric cardiology

authors： Cleemann L,Mortensen KH,Holm K,Smedegaard H,Skouby SO,Wieslander SB,Leffers AM,Leth-Espensen P,Pedersen EM,Gravholt CH

更新日期：2010-05-01 00:00:00

abstract：:Plastic bronchitis (PB) is a poorly understood disease that can complicate any underlying pulmonary disease. However, it appears to most often occur in patients with surgically palliated congenital heart disease, particularly after the Fontan procedure. Few data exist about the prevalence and etiology of PB in this po...

journal_title：Pediatric cardiology

authors： Caruthers RL,Kempa M,Loo A,Gulbransen E,Kelly E,Erickson SR,Hirsch JC,Schumacher KR,Stringer KA

更新日期：2013-02-01 00:00:00

abstract：:For adults with sickle cell disease (SCD), cardiac changes are well described and may account for up to one-fourth of disease-related mortality. Much less is known about heart disease in pediatric SCD patients. This retrospective study analyzed a contemporary cohort of children with SCD followed at a single tertiary c...

journal_title：Pediatric cardiology

authors： Doshi AR,Pauliks LB

更新日期：2013-04-01 00:00:00

abstract：:This review outlines the morphologic and pathogenetic characteristics of congenital polyvalvular disease. Two cases are used for exemplification. The macroscopic and histologic features of the valves as well as associated cardiac lesions and clinical syndromes are described, followed by a discussion of morphogenesis o...

journal_title：Pediatric cardiology

authors： Bartram U,Bartelings MM,Kramer HH,Gittenberger-de Groot AC

更新日期：2001-03-01 00:00:00

abstract：:Debilitating cardiomyocyte loss underlies the progression to heart failure. Although there have been significant advances in treatment, current therapies are intended to improve or preserve heart function rather than regenerate lost myocardium. A major hurdle in implementing a cell-based regenerative therapy is the in...

journal_title：Pediatric cardiology

authors： Willems E,Bushway PJ,Mercola M

更新日期：2009-07-01 00:00:00

abstract：:Arrhythmias in pregnancy are becoming more common given more available and effective medical, ablation and device treatment options. Several changes associated with pregnancy, increased blood volume, cardiac output, and heart rate secondary to an increased sympathetic state, facilitate more frequent occurrences of arr...

journal_title：Pediatric cardiology

authors： Friday KP,Moak JP,Fries MH,Iqbal SN

更新日期：2015-10-01 00:00:00

abstract：:This study is presented to identify and characterize the spectrum of the cardiovascular anomalies in children presenting with Williams-Beuren syndrome and cardiovascular anomalies at The Hospital for Sick Children, Toronto from 1966 to 1988. Forty-nine children were diagnosed and followed. The female to male ratio was...

journal_title：Pediatric cardiology

authors： Zalzstein E,Moes CA,Musewe NN,Freedom RM

更新日期：1991-10-01 00:00:00

abstract：:Anomalous origin of the left coronary artery from the pulmonary artery (ALCAPA) is a rare condition. The majority of cases present with impaired left ventricular function. We report on a premature infant who was diagnosed at a gestational age near term with ALCAPA during routine cardiac examination. The patient showed...

journal_title：Pediatric cardiology

authors： Grosse-Wortmann L,Wenzl T,Hoevels-Guerich HH

更新日期：2006-03-01 00:00:00

abstract：:A 5-year-old child with a Fontan circulation presented with acquired left pulmonary vein occlusion related to a previous surgical repair. We managed this lesion using a hybrid technique to perforate, dilate and stent the obstructed vessel. This approach should be considered when percutaneous access to the pulmonary ve...

journal_title：Pediatric cardiology

authors： Mainzer G,Rosenthal E,Austin C,Morgan G

更新日期：2016-06-01 00:00:00

abstract：:In case of progressive cyanosis after modified Fontan procedure, intrahepatic shunting should be considered. Ligation of the hepatic vein is safe and effective in managing this condition, and it is important to ensure that the pressure difference between superior vena cava and the portal vein system remains minimal af...

journal_title：Pediatric cardiology

authors： Hishitani T,Ogawa K,Hoshino K,Nakamura Y

更新日期：1999-11-01 00:00:00

abstract：:A patient with pulmonary valve stenosis associated with pseudohypertrophic muscular dystrophy is reported. The anomalies were detected by two-dimensional echocardiography and elevated serum enzymes, conformed by right ventriculography and muscles biopsy. The association between these two pathologies is unknown. ...

journal_title：Pediatric cardiology

authors： Xie CH,Xia CS

更新日期：2002-03-01 00:00:00

abstract：:Myocardial blood flow (MBF) was investigated in children (14.2 +/- 5.01 years) with "resolved" coronary involvement after the onset of Kawasaki disease and angiographically normal epicardial coronary arteries. Ten asymptomatic children with a history of Kawasaki disease had electrocardiography, echocardiography, and p...

journal_title：Pediatric cardiology

authors： Hauser M,Bengel F,Kuehn A,Nekolla S,Kaemmerer H,Schwaiger M,Hess J

更新日期：2004-03-01 00:00:00

abstract：:Three infants, each with a clinical picture of dilated cardiomyopathy, underwent endomyocardial biopsy. Immunohistologic analysis revealed chronic myocarditis. In one infant, a postviral etiology of chronic myocarditis could be assessed on the basis of molecular techniques. Therapy with azathioprine and prednisone res...

journal_title：Pediatric cardiology

authors： Schmaltz AA,Demel KP,Kallenberg R,Neudorf U,Kandolf R,Klingel K,Bültmann B

更新日期：1998-05-01 00:00:00

abstract：:Angiotensin-converting enzyme inhibitors (ACEi) are commonly used for pediatric cardiology patients. However, studies examining their safety for neonates with cardiac disease are scarce. The current study aimed to test the hypothesis that ACEi-mediated nephrotoxicity occurs in neonates and may be underappreciated in t...

journal_title：Pediatric cardiology

authors： Lindle KA,Dinh K,Moffett BS,Kyle WB,Montgomery NM,Denfield SD,Knudson JD

更新日期：2014-03-01 00:00:00

abstract：:A blood pump specifically designed to augment flow from the great veins through the lungs would ameliorate the poor physiology of the failing univentricular circulation and result in a paradigm shift in the treatment strategy for Fontan patients. This study is the first to examine mechanical cavopulmonary assistance w...

journal_title：Pediatric cardiology

authors： Throckmorton AL,Lopez-Isaza S,Downs EA,Chopski SG,Gangemi JJ,Moskowitz W

更新日期：2013-08-01 00:00:00

abstract：:The relationship between pulmonary function and right ventricle (RV) in Duchenne muscular dystrophy (DMD) has not been evaluated. Using cardiac magnetic resonance (CMR), we describe the relationship of RV size and function with spirometry in a DMD cohort. Fifty-seven boys undergoing CMR and pulmonary function testing ...

journal_title：Pediatric cardiology

authors： Mehmood M,Ambach SA,Taylor MD,Jefferies JL,Raman SV,Taylor RJ,Sawani H,Mathew J,Mazur W,Hor KN,Al-Khalidi HR

更新日期：2016-06-01 00:00:00

abstract：:We describe a patient diagnosed with a small atrial septal defect (3-4 mm) that had grown to 24 mm in diameter over a six-year period. Timing of transcatheter intervention may be affected by growth of the atrial septal defect and this reports the first case of an atrial septal defect outgrowing the possibility of tran...

journal_title：Pediatric cardiology

authors： Tortoriello TA,McMahon C,Kovalchin JP,Bricker JT,Grifka RG

更新日期：2002-09-01 00:00:00

abstract：:A vascular approach for balloon aortic dilatation in infants is of major concern due to the high risk of femoral artery injury. To overcome this problem, a surgical right carotid artery (RCA) approach has been advocated. No reports are available on RCA after neonatal cutdown. Since 1990, RCA cutdown has been performed...

journal_title：Pediatric cardiology

authors： Borghi A,Agnoletti G,Poggiani C

更新日期：2001-05-01 00:00:00