Abstract:
:This study was undertaken to examine the impact that prenatal diagnosis of congenital heart disease (CHD) has on birth and early neonatal outcomes. The prevalence of prenatally diagnosed CHD has risen over the past decade, but the effect that prenatal diagnosis of CHD has on peripartum decisions remains unclear. No consensus exists on the effect of prenatal diagnosis on neonatal outcomes. Between January 2004 and July 2009, a retrospective chart review of all neonates with CHD admitted to our institution's neonatal intensive care unit was conducted. Obstetric and postnatal variables were collected. Among the 993 subjects, 678 (68.3%) had a prenatal diagnosis. A prenatal diagnosis increased the odds of a scheduled delivery [odds ratio (OR) 4.1, 95% confidence interval (CI) 3.0-5.6] and induction of labor (OR 11.5, 95% CI 6.6-20.1). Prenatal diagnosis was not significantly associated with cesarean delivery when control was used for maternal age, multiple gestation, and presence of extracardiac anomaly. Mean gestational age had no impact on prenatal diagnosis, but prenatal diagnosis was associated with increased odds of delivery before a gestational age of 39 weeks (OR 1.5, 95% CI 1.1-1.9) and decreased odds of preoperative intubation (OR 0.5, 95% CI 0.3-0.6). Prenatal diagnosis did not have an impact on preoperative or predischarge mortality. Prenatal diagnosis was associated with increased odds of a scheduled delivery, birth before a gestational age of 39 weeks, and a decreased need for invasive respiratory support. Prenatal diagnosis of CHD was not associated with preoperative or predischarge mortality.
journal_name
Pediatr Cardioljournal_title
Pediatric cardiologyauthors
Landis BJ,Levey A,Levasseur SM,Glickstein JS,Kleinman CS,Simpson LL,Williams IAdoi
10.1007/s00246-012-0504-4subject
Has Abstractpub_date
2013-03-01 00:00:00pages
597-605issue
3eissn
0172-0643issn
1432-1971journal_volume
34pub_type
杂志文章abstract::Embryonic development is a tightly regulated process, and many families of genes functions to provide a regulatory genetic network to achieve such a program. The homeobox genes are an extensive family that encodes transcription factors with a characteristic 60-amino acid homeodomain. Mutations in these genes or in the...
journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0179-x
更新日期:2012-08-01 00:00:00
abstract::Percutaneous balloon aortic valvuloplasty was attempted in an eight-month-old infant with severe aortic valve stenosis. The procedure resulted in a fall in the resting transvalvular systolic pressure gradient from 106 mmHg to 40 mmHg and no aortic regurgitation. Clinical and Doppler echocardiography findings suggest p...
journal_title:Pediatric cardiology
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更新日期:1985-01-01 00:00:00
abstract::We report our experience with asymptomatic valvar aortic stenosis diagnosed during infancy. During the period between November 1, 1986 and October 31, 1992 a total of 13 infants were diagnosed with asymptomatic aortic stenosis, 5 of whom showed rapid progression over the first 2 years of life. Two of these asymptomati...
journal_title:Pediatric cardiology
pub_type: 杂志文章
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
pub_type: 杂志文章,多中心研究
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更新日期:2015-10-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
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更新日期:2010-01-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章,多中心研究
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
pub_type: 杂志文章,多中心研究
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journal_title:Pediatric cardiology
pub_type: 杂志文章
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abstract::This study aimed to determine the dimensions of the thoracic aorta and the predictors of aortic dimensions in girls and young women with Turner syndrome (TS). A cross-sectional study was performed at a secondary care center. The study compared 41 TS patients with 50 healthy age-matched control subjects. The mean age o...
journal_title:Pediatric cardiology
pub_type: 杂志文章
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更新日期:2010-05-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-012-0430-5
更新日期:2013-02-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
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更新日期:2013-04-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
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更新日期:2001-03-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/s00246-009-9409-2
更新日期:2009-07-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章,评审
doi:10.1007/s00246-015-1232-3
更新日期:2015-10-01 00:00:00
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journal_title:Pediatric cardiology
pub_type: 杂志文章
doi:10.1007/BF02310569
更新日期:1991-10-01 00:00:00
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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journal_title:Pediatric cardiology
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更新日期:2014-03-01 00:00:00
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journal_title:Pediatric cardiology
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更新日期:2013-08-01 00:00:00
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journal_title:Pediatric cardiology
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更新日期:2016-06-01 00:00:00
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