Interventional VSD-Closure with the Nit-Occlud® Lê VSD-Coil in 110 Patients: Early and Midterm Results of the EUREVECO-Registry.

Abstract:

:In August 2010, the Nit-Occlud® Lê (EUREVECO) became available for transcatheter coil occlusion of ventricular septal defects (VSDs). Retrospective European Registry for VSD Closure using the Nit-Occlud® Lê-VSD-Coil; analysis of the feasibility, results, safety and follow-up of VSD-closure over a 3-year period in 18 European centers. In 102 of 111 patients (female 66), successful VSD closure was performed (mean age 8.2 years, mean weight 28.82 kg), 81 perimembranous VSDs (48 with aneurysm), 30 muscular VSDs, mean procedure time was 121.1 min, and mean fluoroscopy time was 26.3 min. Short- and midterm term follow-up was possible in 100/102 patients, there was 1 embolization and 1 explantation after 24 months. Immediate complete closure occurred in 49 of 101 patients (48.5%), trivial residual shunt was present in 51 (50.0%), closure rate was 95% after 6 months and 97% after 1 year. Out of the 102 patients, there were 2 severe complications (1.8%) (1 severe hemolysis, 1 embolization) and 8 moderate/transient (=7.2%) including 1 transient AV block. During a mean follow-up period of 31.3 months (range 24-48) and a total follow-up time of 224.75 patient years, no further problems occurred. VSD closure with the Nit-Occlud® Lê VSD coil is feasible and safe with a minimal risk of severe side effects. The long-term effects and safety require further clinical follow-up studies.

journal_name

Pediatr Cardiol

journal_title

Pediatric cardiology

authors

Haas NA,Kock L,Bertram H,Boekenkamp R,De Wolf D,Ditkivskyy I,Freund MW,Gewillig M,Happel CM,Herberg U,Karthasyan E,Kozlik-Feldmann R,Kretschmar O,Kuzmenko Y,Milanesi O,Mueller G,Pongiglione G,Schubert S,Tarusinov G,

doi

10.1007/s00246-016-1502-8

subject

Has Abstract

pub_date

2017-02-01 00:00:00

pages

215-227

issue

2

eissn

0172-0643

issn

1432-1971

pii

10.1007/s00246-016-1502-8

journal_volume

38

pub_type

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