Pseudosarcoma of the esophagus.

abstract：:The authors report an unusual case of in situ follicular lymphoma associated with progressive transformation of the germinal centers. The patient was a 74-year-old Chinese woman with sequential lymphadenopathy in the right and left cervical regions over a period of 2 months. The first biopsy revealed in situ follicula...

journal_title：Human pathology

authors： Li JN,Zhang WY,Tang Y,Li GD,Dong DD

更新日期：2012-01-01 00:00:00

abstract：:Twelve cases of pure adenoid cystic carcinoma of the breast were reviewed. Patients ranged in age from 34 to 69 years. Seven carcinomas were in the right breast, and five in the left; five of the 12 were located in the central region of the breast, five in the upper outer quadrant, and the two in the upper inner and l...

journal_title：Human pathology

authors： Ro JY,Silva EG,Gallager HS

更新日期：1987-12-01 00:00:00

abstract：:Nested urothelial carcinoma (UC) is a rare histologic variant of UC, characterized by deceptively bland histologic features resembling von Brunn's nests but usually with a poor outcome. In our experience, this variant is frequently misclassified or underrecognized as its clinicopathologic spectrum is not well defined....

journal_title：Human pathology

authors： Wasco MJ,Daignault S,Bradley D,Shah RB

更新日期：2010-02-01 00:00:00

abstract：:We reviewed open lung biopsies from 35 patients with Wegener's (pathergic) granulomatosis in order to study the histogenesis of the pulmonary lesions and to identify the early lesions. The process of pathergic necrosis is fundamental in the production of extravascular and vascular lesions and was divided into micronec...

journal_title：Human pathology

authors： Mark EJ,Matsubara O,Tan-Liu NS,Fienberg R

更新日期：1988-09-01 00:00:00

abstract：:The reliability of a diagnostic test depends on the reproducibility of the result. Many clinical diagnostic tests can be quantified with established ranges and standard deviations. Other tests are more subjective, such as those that depend on analysis of a visual image with an increased possibility of variance in the ...

journal_title：Human pathology

authors： Farmer ER,Gonin R,Hanna MP

更新日期：1996-06-01 00:00:00

abstract：:We describe the pathology of 5 patients with germline PRKACA copy number gain and Cushing syndrome: 4 males and 1 female, aged 2 to 43 years, including a mother and son. Imaging showed normal or slightly enlarged adrenal glands in 4 patients and a unilateral mass in the fifth. Biochemically, the patients had corticotr...

journal_title：Human pathology

authors： Carney JA,Lyssikatos C,Lodish MB,Stratakis CA

更新日期：2015-01-01 00:00:00

abstract：:Histopathologic lesions in the central nervous system (CNS) of 400 autopsy cases of the acquired immunodeficiency syndrome (AIDS) collected from 1982 to 1990 were studied. Lesions most closely associated with human immunodeficiency virus (HIV) infection in the CNS (perivascular macrophages, nodular encephalomyelitis, ...

journal_title：Human pathology

authors： Rhodes RH

更新日期：1993-11-01 00:00:00

abstract：:An unusual case of acute respiratory obstruction caused by multicentric granular cell tumors of the laryngotracheobronchial tree is presented. The patient also had granular cell tumors in the tongue, vulva, and chest wall. Multiplicity of the lesions in the left lung and recurrent episodes of intercurrent pulmonary in...

journal_title：Human pathology

authors： Majmudar B,Thomas J,Gorelkin L,Symbas PN

更新日期：1981-03-01 00:00:00

abstract：:The diagnosis of microscopic colitis (MC) relies on specific histopathological findings in colon biopsies. The number of biopsies needed to diagnose MC remains disputed. The aim of the study was to determine the number and site of biopsies necessary for the diagnosis and the effect of perpendicular orientation when em...

journal_title：Human pathology

authors： Kanstrup Fiehn AM,Heiberg Engel PJ,Lanzarotto F,Goudkade D,Landolfi S,Munck LK,Villanacci V

更新日期：2020-09-01 00:00:00

abstract：:Mammary analogue secretory carcinoma is a recently described salivary gland neoplasm defined by ETV6-NTRK3 gene fusion. Mammary analogue secretory carcinoma's morphology is not entirely specific and overlaps with other salivary gland tumors. Documenting ETV6 rearrangement is confirmatory, but most laboratories are not...

journal_title：Human pathology

authors： Bishop JA,Yonescu R,Batista D,Begum S,Eisele DW,Westra WH

更新日期：2013-10-01 00:00:00

abstract：:Mucoepidermoid carcinoma of the breast is a rare entity with specific morphologic and immunohistochemical features similar to its salivary gland counterpart. In the 28 reported cases to date, there has not been a comparison of the molecular characteristics of this tumor with salivary gland mucoepidermoid carcinomas. H...

journal_title：Human pathology

authors： Camelo-Piragua SI,Habib C,Kanumuri P,Lago CE,Mason HS,Otis CN

更新日期：2009-06-01 00:00:00

abstract：:Abnormal nuclear megakaryocytic staining for phospho-STAT5 (pSTAT5) correlates with JAK2 V617F mutational status in non-chronic myelogenous leukemia chronic myeloproliferative disorders. However, a proportion of wild-type JAK2 non-chronic myelogenous leukemia chronic myeloproliferative disorders cases also demonstrate...

journal_title：Human pathology

authors： Gibson SE,Schade AE,Szpurka H,Bak B,Maciejewski JP,Hsi ED

更新日期：2008-07-01 00:00:00

abstract：:Esophageal adenocarcinoma often presents at an advanced stage and has a dismal prognosis. Current prognostic markers have limited utility. ARID1A is implicated as a tumor suppressor gene in esophageal adenocarcinoma. Loss of ARID1A expression correlates with DNA mismatch repair (MMR) protein deficiency in other tumors...

journal_title：Human pathology

authors： Lowenthal BM,Nason KS,Pennathur A,Luketich JD,Pai RK,Davison JM,Ma C

更新日期：2019-12-01 00:00:00

abstract：:This article has been withdrawn at the request of the author(s) and/or editor. The Publisher apologizes for any inconvenience this may cause. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy. ...

journal_title：Human pathology

authors： Genta RM

更新日期：2011-04-17 00:00:00

abstract：:Inflammatory pseudotumors (IPs), mostly benign lesions characterized by fibrotic ground tissue and polyclonal mononuclear infiltrate, may affect all organ systems. IPs originating in the central nervous system (IP-CNS) are very rare, and their distinct histopathologic features are poorly characterized. Three otherwise...

journal_title：Human pathology

authors： Häusler M,Schaade L,Ramaekers VT,Doenges M,Heimann G,Sellhaus B

更新日期：2003-03-01 00:00:00

abstract：:Preserving small pieces of frozen tissue for possible future ancillary studies ("tumor banking") usually involves either placing a small piece of tissue in a cryovial and snap freezing it in liquid nitrogen or embedding and freezing the tissue in a block of cryopreservation medium, such as optimal cutting temperature ...

journal_title：Human pathology

authors： Loken SD,Demetrick DJ

更新日期：2005-09-01 00:00:00

abstract：:We report the molecular characterization of 8 primary gastric carcinomas, corresponding xenografts, and 2 novel gastric carcinoma cell lines. We compared the tumors and cell lines, with respect to histology, immunohistochemistry, copy number, and hypermethylation of up to 38 genes using methylation-specific multiplex ...

journal_title：Human pathology

authors： Milne AN,Sitarz R,Carvalho R,Polak MM,Ligtenberg M,Pauwels P,Offerhaus GJ,Weterman MA

更新日期：2007-06-01 00:00:00

abstract：:We have previously shown that necrotic tumors retain their immunoreactivity for a range of cytokeratin antibodies. Some thyroid tumors undergo extensive necrosis after fine-needle aspiration (FNA) procedures. We evaluated the sensitivity of antibodies on necrotic thyroid tumors by examining a series of thyroid tumors ...

journal_title：Human pathology

authors： Judkins AR,Roberts SA,Livolsi VA

更新日期：1999-11-01 00:00:00

abstract：:Enteroendocrine cell dysgenesis was observed in 3 patients with intestinal failure of unknown cause. Enteroendocrine cell dysgenesis is a congenitally acquired life-threatening malabsorptive condition with a unique clinical phenotype paired with a histologically identifiable disease pattern. Two cases were first prese...

journal_title：Human pathology

authors： Cortina G,Smart CN,Farmer DG,Bhuta S,Treem WR,Hill ID,Martín MG

更新日期：2007-04-01 00:00:00

abstract：:Epigenetic factors contribute to carcinogenesis, tumor promotion, and chemoresistance. Histone deacetylases (HDACs) are epigenetic regulators that primarily cause chromatin compaction, leading to inaccessibility of promoter regions and eventually gene silencing. Many cancer entities feature overexpression of HDACs. Cu...

journal_title：Human pathology

authors： Klieser E,Urbas R,Stättner S,Primavesi F,Jäger T,Dinnewitzer A,Mayr C,Kiesslich T,Holzmann K,Di Fazio P,Neureiter D,Swierczynski S

更新日期：2017-07-01 00:00:00

abstract：:The aims of this investigation were to compare quantitative with qualitative analysis of fluorescent in situ hybridization (FISH) centromere signals in interphase breast cancer cell nuclei and to evaluate the possible clinical utility of detecting numerical abnormalities of chromosomes 11 and 17 by FISH in the preoper...

journal_title：Human pathology

authors： McManus DT,Patterson AH,Maxwell P,Hamilton PW,Anderson NH,Caughley LM,Toner PG

更新日期：1999-02-01 00:00:00

abstract：:After endoscopic resection of early gastric cancer (EGC), it is imperative to accurately determine whether follow-up surgery is indicated, since this technique is used as a first line of treatment. Herein, we developed a scoring system to indicate the risk of lymph node metastasis in submucosal EGC (smEGC), and presen...

journal_title：Human pathology

authors： Kim JY,Kim WG,Jeon TY,Kim GH,Jeong EH,Kim DH,Park DY,Lauwers GY

更新日期：2013-12-01 00:00:00

abstract：:Insulin-like growth factor II messenger RNA (mRNA)-binding protein 3 (IMP3) is an oncofetal protein that promotes tumor progression and metastasis in a number of malignancies. However, the clinical significance of IMP3 expression in squamous cell carcinoma (SCC) of the uterine cervix is unclear. In this study, the cor...

journal_title：Human pathology

authors： Wei Q,Yan J,Fu B,Liu J,Zhong L,Yang Q,Zhao T

更新日期：2014-11-01 00:00:00

abstract：:Histopathologic diagnosis of adrenocortical tumors is based on adverse features that indicate malignant potential. Proliferation index has served as a supplemental tool in assessing the malignant potential of adrenocortical tumors. None of the current histologic classification systems can sufficiently accurately predi...

journal_title：Human pathology

authors： Pennanen M,Heiskanen I,Sane T,Remes S,Mustonen H,Haglund C,Arola J

更新日期：2015-03-01 00:00:00

abstract：:Digitization of glass slides holds great promise for increasing workflow efficiency, but current applications have not gained widespread acceptance. Applications to date have not taken into consideration pathologists' workflow patterns, and as a result many find navigation cumbersome and interpretation more challengin...

journal_title：Human pathology

authors： Velez N,Jukic D,Ho J

更新日期：2008-09-01 00:00:00

abstract：:Lymphangioleiomyomatosis (LAM) is a rare disease which afflicts young women of childbearing age. Recently, it has been listed as an indication for lung transplantation. We describe a case of recurrent LAM in a 31-year-old woman occurring in the allograft of a male donor after single lung transplantation. Nonisotopic i...

journal_title：Human pathology

authors： Bittmann I,Dose TB,Müller C,Dienemann H,Vogelmeier C,Löhrs U

更新日期：1997-12-01 00:00:00

abstract：:Oral squamous cell carcinoma (OSCC) is the most common oral cancer, and major efforts is being made to identify molecular markers capable to differentiate oral potentially malignant lesions (OPMLs) with indolent course from lesions with aggressive behavior. We undertook a study to evaluate if gain of the human telomer...

journal_title：Human pathology

authors： Dorji T,Monti V,Fellegara G,Gabba S,Grazioli V,Repetti E,Marcialis C,Peluso S,Di Ruzza D,Neri F,Foschini MP

更新日期：2015-09-01 00:00:00

abstract：:Our previous investigations of transforming growth factor types beta 1 and beta 2 (TGF beta s) showed negative or positive autocrine growth regulation of gliomas in vitro. Near-diploid gliomas were inhibited by the TGF beta s, whereas a stimulatory response correlated with progressive anaplasia and karyotypic divergen...

journal_title：Human pathology

authors： Jennings MT,Kaariainen IT,Gold L,Maciunas RJ,Commers PA

更新日期：1994-05-01 00:00:00

abstract：:Sneddon's syndrome is a potentially fatal arterio-occlusive disorder characterized by generalized livedo racemosa and cerebrovascular lesions. Skin biopsies often fail to yield diagnostic arterial lesions. In the present series, affected vessels were found in skin biopsies from 12 of 15 patients with Sneddon's syndrom...

journal_title：Human pathology

authors： Zelger B,Sepp N,Schmid KW,Hintner H,Klein G,Fritsch PO

更新日期：1992-06-01 00:00:00

abstract：:The case of a patient in whom idiopathic thrombocytopenic purpura (ITP) was associated with diffuse splenic histiocytosis is described; the patient's subsequent sphingomyelinase level was at the lower limits of the normal range. The patient's splenic lecithin:sphingomyelin ratio was not significantly different from th...

journal_title：Human pathology

authors： Hom BL,Belles Q,Oishi N

更新日期：1985-11-01 00:00:00