Correlation between exocrine pancreatic secretion and serum concentration of human pancreatic polypeptide in chronic pancreatitis.

Abstract:

:Concentrations of human pancreatic polypeptide (HPP) in serum were measured in the fasting state and after a meal in 19 control subjects and 24 patients with chronic pancreatitis (CP). The severity of CP was characterized on the basis of the duodenal lipase concentration after a test meal (Lundh test). Basal and postprandial HPP concentrations were significantly (p less than 0.01) decreased in severe and moderate chronic pancreatitis and in diabetes secondary to pancreatitis. There was only a weak correlation (r = 0.44; p less than 0.05) between exocrine secretion and delta HPP in CP. Fifty-eight percent of patients with CP had serum concentrations of HPP within the normal range, limiting the value of serum HPP measurement in the diagnosis of CP.

journal_name

Scand J Gastroenterol

authors

Andersen BN,Hagen C,Klein HC,Stadil F,Worning H

doi

10.3109/00365528009181517

subject

Has Abstract

pub_date

1980-01-01 00:00:00

pages

699-704

issue

6

eissn

0036-5521

issn

1502-7708

journal_volume

15

pub_type

杂志文章
  • Patients and gastroenterologists' perceptions of treatments for inflammatory bowel diseases: do their perspectives match?

    abstract:BACKGROUND:Perceptions of appropriateness of treatments may differ between gastroenterologists (GIs) and inflammatory bowel disease (IBD) patients. The aim of this study was to explore and compare GIs' and patients' perceptions of risks and benefits of treatments and prioritization of expected outcomes. METHODS:Four v...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2016.1147065

    authors: Vaucher C,Maillard MH,Froehlich F,Burnand B,Michetti P,Pittet V

    更新日期:2016-09-01 00:00:00

  • A case of adenocarcinoma of the small intestine in a Japanese patient with Crohn disease: a report with immunohistochemical and oncogenic analyses.

    abstract::We report a rare case of Crohn disease accompanied by a small-bowel carcinoma that developed in a 54-year-old Japanese man. The ulcerating tumor, which histologically proved to be a poorly differentiated adenocarcinoma and dysplasia surrounding the carcinoma, was located in the diseased ileum. The Ki-67 immunoreactive...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655299750024995

    authors: Uesugi H,Mitomi H,Sada M,Takahashi H,Kobayashi K,Igarashi M,Katsumata T,Ihara A,Ohtani Y,Ikeda S,Okayasu I

    更新日期:1999-11-01 00:00:00

  • Bioavailability of prednisolone in patients with intestinal malabsorption: the importance of measuring serum protein-binding.

    abstract::The effect of intestinal malabsorption on the oral bioavailability of prednisolone has been studied in six patients with celiac disease and in six patients with malabsorption of various etiologies, five of whom had undergone gut resections. The serum protein-binding of prednisolone was measured in five patients with c...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528309181635

    authors: Bergrem H,Opedal I

    更新日期:1983-05-01 00:00:00

  • The diagnostic value of the D-xylose absorption test in adult coeliac disease.

    abstract::The 25-g D-xylose absorption test was assessed in a total of 40 adult patients with coeliac disease before and after treatment and in 25 control patients. Because of a large overlap neither the urinary excretion rates nor the 1-h blood concentrations were of any use in the assessment of the individual patients. The ov...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528708996467

    authors: Bodé S,Gudmand-Høyer E

    更新日期:1987-12-01 00:00:00

  • Surgical outcome evaluation of perforated gastric cancer: from the aspects of both acute care surgery and surgical oncology.

    abstract:BACKGROUND:Perforated gastric cancer (PGC) is a rare condition of gastric cancer (GC). In this study, we sought to assess the outcome of PGC from the aspects of both acute care surgery and surgical oncology at a single institute, Chang Gung Memorial Hospital (CGMH). METHODS:From 1997 to 2013, 6864 patients were diagno...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2017.1369562

    authors: Wang SY,Hsu CH,Liao CH,Fu CY,Ouyang CH,Cheng CT,Hsu JT,Yeh TS,Yeh CN

    更新日期:2017-12-01 00:00:00

  • High Rate of Positive Anti-Tissue Transglutaminase Antibodies in Chronic Liver Disease.

    abstract:BACKGROUND:Since the recognition of tissue transglutaminase (tTG) as the target antigen of anti-endomysium antibodies, several ELISA assays using either guinea pig or human recombinant tTG have been developed. The aim of the study was to compare the behaviour of anti-tTG and anti-endomysium antibodies assays in coeliac...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520310000438

    authors: Vecchi MD,Folli C,Donato MF,Formenti S,Arosio E,Franchis R

    更新日期:2003-01-01 00:00:00

  • Apoptosis, proliferation and differentiation patterns are influenced by Zebularine and SAHA in pancreatic cancer models.

    abstract:OBJECTIVE:Pancreatic cancer continues to be an urgent clinical problem. We used the novel DNA methyltransferase inhibitor Zebularine and the histone deacetylase inhibitor SAHA to investigate the epigenetic influence on viability and differentiation of the pancreatic cancer cell lines YAP C, DAN G and Panc-89 in vitro a...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520600874198

    authors: Neureiter D,Zopf S,Leu T,Dietze O,Hauser-Kronberger C,Hahn EG,Herold C,Ocker M

    更新日期:2007-01-01 00:00:00

  • The compact Erlangen Active Simulator for Interventional Endoscopy: a prospective comparison in structured team-training courses on "endoscopic hemostasis" for doctors and nurses to the "Endo-Trainer" model.

    abstract:BACKGROUND:In 1997 Hochberger and Neumann presented the "Erlangen Biosimulation Model" (commercialized as the "Erlangen Endo-Trainer") at various national and international meetings. The new compactEASIE is a simplified version of the original "Biosimulation Model" (Endo-Trainer) and is specially designed for easy hand...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520410006765

    authors: Hochberger J,Euler K,Naegel A,Hahn EG,Maiss J

    更新日期:2004-09-01 00:00:00

  • Endoscopic management of refractory gastroesophageal reflux disease.

    abstract:OBJECTIVE:Despite the therapeutic and surgical interventions for the management of gastroesophageal reflux disease (GERD), yet the high cost and the post-operative complications had led to a significant socioeconomic burden. The aim was to evaluate the safety and efficacy of endoscopic band ligation (EBL) in the manage...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.1080/00365521.2018.1445775

    authors: Seleem WM,Hanafy AS,Mohamed SI

    更新日期:2018-04-01 00:00:00

  • Aspects on diagnosis and treatment of the foregut carcinoid syndrome.

    abstract::Eight patients with the foregut carcinoid syndrome (two gastric and six bronchial primary tumors) are reported. The patients presented with complex clinical symptoms including ectopic production of adrenocorticotrophic hormone and growth hormone-releasing factors. The most alarming symptoms were facial flush and edema...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529209000106

    authors: Ahlman H,Wängberg B,Nilsson O,Grimelius L,Granérus G,Modlin IM,Stenqvist O,Scherstén T

    更新日期:1992-06-01 00:00:00

  • Influence of alcohol consumption on the association between serum lipids and colorectal adenomas.

    abstract:BACKGROUND:There have been no reports that low serum cholesterol levels increase the risk of colorectal adenoma, although many studies have shown that they do increase the risk of colorectal cancer. Alcohol intake, which is associated with a risk of colorectal adenomas, and serum cholesterol levels are closely related....

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655202761020597

    authors: Fujimori S,Kishida T,Mitsui K,Yonezawa M,Nagata K,Shibata Y,Tanaka S,Tatsuguchi A,Sato J,Yokoi K,Tanaka N,Ohaki Y,Sakamoto C,Kobayashi M

    更新日期:2002-11-01 00:00:00

  • Heparin effect on thromboelastography after transjugular intrahepatic portosystemic shunt procedure.

    abstract:OBJECTIVE:In patients with cirrhosis and bacterial infection there is impaired coagulation and a heparin effect on thromboelastography (TEG). Our aim was to assess the presence of a heparin effect on heparinase I-modified TEG in patients before and after transjugular intrahepatic portosystemic shunt (TIPS). Our hypothe...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365520903342174

    authors: Thalheimer U,Triantos C,Samonakis D,Patch D,Burroughs AK

    更新日期:2009-01-01 00:00:00

  • Genetic and transcriptional analysis of inflammatory bowel disease-associated pathways in patients with GUCY2C-linked familial diarrhea.

    abstract:OBJECTIVE:Activating mutations in the GUCY2C gene, which encodes the epithelial receptor guanylate cyclase C, cause diarrhea due to increased loss of sodium chloride to the intestinal lumen. Patients with familial GUCY2C diarrhea syndrome (FGDS) are predisposed to inflammatory bowel disease (IBD). We investigated wheth...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2018.1521867

    authors: Tronstad RR,Polushina T,Brattbakk HR,Stansberg C,von Volkmann HL,Hanevik K,Ellinghaus E,Jørgensen SF,Ersland KM,Pham KD,Gilja OH,Hovdenak N,Hausken T,Vatn MH,Franke A,Knappskog PM,Le Hellard S,Karlsen TH,Fiskerstrand

    更新日期:2018-01-01 00:00:00

  • Association of irritable bowel syndrome and venous thromboembolism.

    abstract:OBJECTIVE:Inflammatory bowel disease (IBD) is associated with venous thromboembolism (VTE). Whether functional gastrointestinal disorders, such as irritable bowel syndrome (IBS), are associated with VTE has not been determined. This nationwide study aimed to determine the risk of VTE in IBS outpatients in primary and s...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365521.2018.1465118

    authors: Zöller B,Ohlsson H,Waehrens R,Sundquist J,Sundquist K

    更新日期:2018-01-01 00:00:00

  • Synthetic 13C-dipeptide breath test for the rapid assessment of pancreatic exocrine insufficiency in rats.

    abstract:OBJECTIVE:(13)C-breath tests have been investigated in order to assess pancreatic exocrine function using various (13)C-compounds, but they have not been accepted for routine clinical use. One of the barriers to their acceptance is that these tests are time-consuming and require up to several hours for breath collectio...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520601155472

    authors: Kohno T,Ito A,Hosoi I,Hirayama J,Shibata K

    更新日期:2007-08-01 00:00:00

  • The effect of proteolytic enzymes on the vitamin B12-binding proteins of human gastric juice and saliva.

    abstract::Pepsin had no effect on the vitamin B12 binder in human saliva (R-binder), while trypsin was found to reduce the apparent molecular weight of the R-binder and to release vitamin B12 from the R-B12complex of human saliva and human gastric juice (HGJ). Trypsin had no effect on the molecular weight and biological activit...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365527909181412

    authors: Andersen KJ,von der Lippe G

    更新日期:1979-01-01 00:00:00

  • Sexuality in patients with ulcerative colitis before and after restorative proctocolectomy: a prospective study.

    abstract:BACKGROUND:The purpose of this study was to assess sexuality in patients with ulcerative colitis (UC), before and one year after an ileal-pouch anal anastomosis (IPAA). METHODS:Group I comprised 14 medically treated patients (7 M) and Group II comprised 29 patients (18 M), operated with colectomy and ileostomy, with p...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520310008449

    authors: Berndtsson I,Oresland T,Hultén L

    更新日期:2004-04-01 00:00:00

  • Changes in oesophageal pH associated with gastro-oesophageal reflux. Are traditional criteria sensitive for detection of reflux?

    abstract::Traditionally, gastro-oesophageal reflux is deemed to have occurred when oesophageal pH falls below 4. Other 'non-traditional' pH changes that do not fall below pH 4, that fall below 4 for only brief intervals, or that occur when basal pH is less than 4 are usually disregarded. The aim of this study was to determine w...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529309104017

    authors: Wyman JB,Dent J,Holloway RH

    更新日期:1993-09-01 00:00:00

  • Hyperglycaemia attenuates erythromycin-induced acceleration of solid-phase gastric emptying in idiopathic and diabetic gastroparesis.

    abstract:BACKGROUND:Erythromycin has recently been found to be a gastrointestinal prokinetic agent in humans. Acute hyperglycaemia has been associated with delayed gastric emptying in both healthy controls and diabetic patients. Our aim was to investigate in gastroparetic patients (diabetics and idiopathics) whether hyperglycae...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1080/003655299750026416

    authors: Petrakis IE,Vrachassotakis N,Sciacca V,Vassilakis SI,Chalkiadakis G

    更新日期:1999-04-01 00:00:00

  • Inhibition of hepatic chylomicron remnant uptake in the cholestatic rat.

    abstract::[3H]retinal- or [3h]cholesterol- and [14C]fatty acid-labeled chylomicrons and chylomicron remnants were injected intravenously into normal rats and rats subjected to partial or total obstruction of the bile duct 8 or 48 h earlier. The clearance from plasma of the [3H]retinyl and the [3H]cholesteryl esters in 30-120 mi...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528009181798

    authors: Larsson B,Nilsson A

    更新日期:1980-01-01 00:00:00

  • Cholecystectomy in Sweden 1987-99: a nationwide study of mortality and preoperative admissions.

    abstract:OBJECTIVE:Information on mortality after cholecystectomy in defined populations is limited. In this study we examined the case fatality rates and mortality ratios, based on register data. MATERIAL AND METHODS:Hospital discharge and death certificate data were linked for all patients undergoing cholecystectomy in Swede...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520510023972

    authors: Nilsson E,Fored CM,Granath F,Blomqvist P

    更新日期:2005-12-01 00:00:00

  • Phenol toxicity and conjugation in human colonic epithelial cells.

    abstract:BACKGROUND:Colonic epithelial cells are exposed to a range of potentially harmful luminal factors. including phenols, but it is unresolved whether these compounds impair the integrity of the epithelium. The aim of this study was to describe the effect of phenol exposure on human colonic epithelial cells in vitro and th...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655202753387392

    authors: Pedersen G,Brynskov J,Saermark T

    更新日期:2002-01-01 00:00:00

  • Centralized registration, prophylactic examination, and treatment results in improved prognosis in familial adenomatous polyposis. Results from the Danish Polyposis Register.

    abstract:BACKGROUND:Over the last few decades numerous regional and national registers have been established all over the world with the aim of improving survival in familial adenomatous polyposis (FAP). The Danish Polyposis Register was founded in 1971 and coordinates the screening and subsequent prophylactic colectomy of FAP ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365529509096343

    authors: Bülow S,Bülow C,Nielsen TF,Karlsen L,Moesgaard F

    更新日期:1995-10-01 00:00:00

  • Interdigestive motility and motilin in hypophysectomized patients.

    abstract::Basal fluctuations of motilin and their correlation to intestinal motor activity were studied in five hypophysectomized (anterior lobe resection) patients. A cyclic pattern of motor activity identical to the one described in normal volunteers was observed. The mean interval between two activity fronts (AF) was 115 min...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528809093850

    authors: Peeters TL,Janssens J,Plets C,Vantrappen G

    更新日期:1988-01-01 00:00:00

  • Helicobacter pylori eradication in the healing of atrophic gastritis: a one-year prospective study.

    abstract:OBJECTIVE:Whether gastric atrophy or intestinal metaplasia heals after successful treatment of Helicobacter pylori (H. pylori) infection is still a matter of controversy. The aim of this article was to clarify whether, after one year, H. pylori eradication is associated with healing in glandular atrophy and intestinal ...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1080/00365520500463175

    authors: Arkkila PE,Seppälä K,Färkkilä MA,Veijola L,Sipponen P

    更新日期:2006-07-01 00:00:00

  • Does heparin coating reduce encrustation of biliary plastic endoprostheses? A prospective randomized trial.

    abstract:OBJECTIVE:Common bile duct stenting is widely performed for bridging benign and malignant obstructions. A major limitation is early stent occlusion making regular stent exchange necessary. Covalent binding of glycosaminoglycanes to polyethylene stents proved to reduce encrustation in urological implants. Since developm...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章,随机对照试验

    doi:10.3109/00365521.2012.711849

    authors: Farnbacher MJ,Lederer R,Blana A,Schneider HT

    更新日期:2012-10-01 00:00:00

  • Gastric IgA in cystic fibrosis in relation to the migrating motor complex.

    abstract:BACKGROUND:Gastrointestinal symptoms in cystic fibrosis are frequent, but little is known about the underlying pathophysiology. Mucosal secretion of IgA is important for the immunologic function in the human gastrointestinal tract but has not been studied in cystic fibrosis. The aim of this study was to quantify the re...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/003655201750313379

    authors: Hallberg K,Mattsson-Rydberg A,Fändriks L,Strandvik B

    更新日期:2001-08-01 00:00:00

  • Development and validation of a theoretical test in non-anaesthesiologist-administered propofol sedation for gastrointestinal endoscopy.

    abstract:OBJECTIVE:Safety with non-anaesthesiologist-administered propofol sedation (NAAP) during gastrointestinal (GI) endoscopy is related to theoretical knowledge. A summative testing of knowledge before attempting supervised nurse-administered propofol sedation (NAPS) in the clinic is advised. The aims of this study were to...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365521.2016.1141433

    authors: Jensen JT,Savran MM,Møller AM,Vilmann P,Hornslet P,Konge L

    更新日期:2016-07-01 00:00:00

  • Degradation of amino acids to short-chain fatty acids in humans. An in vitro study.

    abstract::Short-chain fatty acids (SCFA) originate mainly in the colon through bacterial fermentation of polysaccharides. To test the hypothesis that SCFA may originate from polypeptides as well, the production of these acids from albumin and specific amino acids was examined in a faecal incubation system. Albumin was converted...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.3109/00365528809103964

    authors: Rasmussen HS,Holtug K,Mortensen PB

    更新日期:1988-03-01 00:00:00

  • Anti-CagA and anti-VacA antibodies in Helicobacter pylori-infected patients with and without peptic ulcer disease in Serbia and Montenegro.

    abstract:BACKGROUND:The expression of two Helicobacter pylori proteins, CagA and VacA, is associated with more severe pathogenesis and clinical outcomes of the infection. However, this association varies among geographical regions and ethnic groups. We therefore evaluated CagA and VacA seroprevalence in H. pylori-positive dyspe...

    journal_title:Scandinavian journal of gastroenterology

    pub_type: 杂志文章

    doi:10.1080/00365520310008403

    authors: Sokic-Milutinovic A,Wex T,Todorovic V,Milosavljevic T,Malfertheiner P

    更新日期:2004-03-01 00:00:00