Acute hematological tolerance to multiple fraction, whole body, low dose irradiation in an experimental murine system.

Abstract:

:Using a dose fractionation scheme patterned after the current regimen for treatment of disseminated non-Hodgkin lymphoma, the authors studied the effects of irradiation on progenitor and effector cells for hematopoiesis in five-month-old BC3F1 mice. Fractions of 20 or 50 rad (0.2 or 0.5 Gy) total body irradiation were given twice weekly to a final total dose of 200 or 500 rad (2 or 5 Gy), respectively. Weekly assays revealed a marked, sustained depression of stem cell activity, measured as numbers of spleen colony-forming units (CFU-S) and in vitro colony-forming cells (CFU-C), without corresponding depression of effector cells (red and white cells, and platelets). The lack of correlation between numbers of stem cells and peripheral elements is relevant to clinical assessment of marrow reserve.

journal_name

Radiology

journal_title

Radiology

authors

Melamed JS,Chen MG,Brown JW,Katagiri CA

doi

10.1148/radiology.134.2.7352240

subject

Has Abstract

pub_date

1980-02-01 00:00:00

pages

503-6

issue

2

eissn

0033-8419

issn

1527-1315

journal_volume

134

pub_type

杂志文章
  • Proton spectroscopy of the brain in HIV infection: correlation with clinical, immunologic, and MR imaging findings.

    abstract::Abnormalities at cerebral proton spectroscopy occur in patients with the acquired immunodeficiency syndrome (AIDS). N-acetyl aspartate (NAA) is believed to be a neuronal marker, and neuronal loss is thought to underlie the human immunodeficiency virus (HIV)-associated cognitive/motor complex. The proton spectra in 103...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.188.1.8099750

    authors: Chong WK,Sweeney B,Wilkinson ID,Paley M,Hall-Craggs MA,Kendall BE,Shepard JK,Beecham M,Miller RF,Weller IV

    更新日期:1993-07-01 00:00:00

  • New catheter design and placement technique for pulmonary arteriography.

    abstract::An improved catheter for pulmonary arteriography via the antecubital approach is described. The catheter has been used successfully in 56 patients. ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.163.1.3823450

    authors: Tempkin DL,Ladika JE

    更新日期:1987-04-01 00:00:00

  • Search and nonsearch protocols for radiographic consultation.

    abstract::Six radiologists, acting as radiograph reviewers, used two different consultation protocols to differentiate among 292 ambiguous chest radiographic findings: 120 simulated nodules and 172 normal findings (previous readers' false-positive reports of nodules). The nonsearch protocol identified each finding (by film loca...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.177.3.2244000

    authors: Swensson RG,Theodore GH

    更新日期:1990-12-01 00:00:00

  • Detection of Steatohepatitis in a Rat Model by Using Spectroscopic Shear-Wave US Elastography.

    abstract::Purpose To compare low- versus high-frequency ultrasonographic (US) elastography for detection of steatohepatitis in rats by using histopathologic findings as the reference standard. Materials and Methods Between March and September 2014, after receiving approval from the institutional animal care committee, 60 male S...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2016160308

    authors: Kazemirad S,Zhang E,Nguyen BN,Bodson-Clermont P,Destrempes F,Trudel D,Cloutier G,Tang A

    更新日期:2017-03-01 00:00:00

  • Translating molecular imaging research into radiologic practice: summary of the proceedings of the American College of Radiology Colloquium, April 22-24, 2001.

    abstract::The American College of Radiology (ACR) convened a "think tank" of experts on aspects of molecular imaging. The purposes of the colloquium were to develop scenarios about how molecular imaging would develop in the future and to make recommendations to the ACR about how to prepare radiologists for this important set of...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2222011530

    authors: Hillman BJ,Neiman HL

    更新日期:2002-01-01 00:00:00

  • CT gantry tilt: utility in transthoracic fine-needle aspiration biopsy. Work in progress.

    abstract::The authors used a gantry tilt of 20 degrees in five patients to allow fine-needle aspiration biopsy of peripheral pulmonary lesions that were difficult to approach with a vertical alignment because of overlying ribs. This method allowed a direct approach to the lesion in all five cases, with the entire needle path vi...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.187.3.8497650

    authors: Stern EJ,Webb WR,Gamsu G

    更新日期:1993-06-01 00:00:00

  • Small hepatocellular carcinoma in patients undergoing liver transplantation: detection with CT after injection of iodized oil.

    abstract:PURPOSE:To assess computed tomography (CT) with iodized oil for depiction of small hepatocellular carcinoma (HCC) before liver transplantation. MATERIALS AND METHODS:Thirty-five consecutive cirrhotic patients underwent CT with iodized oil to determine the presence, number, size, and location of possible nodules. All p...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.197.2.7480680

    authors: Taourel PG,Pageaux GP,Coste V,Fabre JM,Pradel JA,Ramos J,Larrey D,Domergue J,Michel H,Bruel JM

    更新日期:1995-11-01 00:00:00

  • Polyclonal human immunoglobulin G labeled with polymeric iron oxide: antibody MR imaging.

    abstract::Human polyclonal immunoglobulin (Ig) G was attached to a monocrystalline iron oxide nanocompound (MION), a small superparamagnetic probe developed for receptor and antibody magnetic resonance (MR) imaging. The resulting complex, MION-IgG, had a slightly negative surface charge, a molecular weight of 150-180 kDa, and 0...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.181.1.1887040

    authors: Weissleder R,Lee AS,Fischman AJ,Reimer P,Shen T,Wilkinson R,Callahan RJ,Brady TJ

    更新日期:1991-10-01 00:00:00

  • Imaging of carotid arteries in symptomatic patients: cost-effectiveness of diagnostic strategies.

    abstract:PURPOSE:To assess the cost-effectiveness of noninvasive imaging strategies in patients who have had a transient ischemic attack (TIA) or minor stroke and are suspected of having significant carotid artery stenosis. MATERIALS AND METHODS:From 1997 through 2000, 350 patients were included in a multicenter blinded consec...

    journal_title:Radiology

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1148/radiol.2331030863

    authors: Buskens E,Nederkoorn PJ,Buijs-Van Der Woude T,Mali WP,Kappelle LJ,Eikelboom BC,Van Der Graaf Y,Hunink MG

    更新日期:2004-10-01 00:00:00

  • MR imaging of mammographically detected clustered microcalcifications: is there any value?

    abstract:PURPOSE:To assess the value of dynamic magnetic resonance (MR) imaging in patients with mammographically detected suspicious microcalcifications. MATERIALS AND METHODS:Sixty-three patients (age range, 31-84 years; mean age, 56 years) with mammographically suspicious clustered microcalcifications underwent dynamic MR i...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.207.3.9609890

    authors: Westerhof JP,Fischer U,Moritz JD,Oestmann JW

    更新日期:1998-06-01 00:00:00

  • Supine pedal venous measurement in patients with venous disease.

    abstract::The measurement of supine pedal venous pressure as a screening test for deep venous thrombosis is re-evaluated. In 83 extremities studied in 50 patients, the false-positive rate was 62%, the false-negative rate 8%. Chronic venous disease, whatever its etiology but particularly in association with the post-phlebitis sy...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/131.1.75

    authors: Martin EC,Cohen L,Sawyer PN,Gordon DH

    更新日期:1979-04-01 00:00:00

  • Hangman's fracture: radiologic assessment in 27 cases.

    abstract::Traumatic spondylolisthesis of C-2, frequently referred to as the hangman's fracture, is typically regarded as a hyperextension injury with rare neurologic sequelae by virtue of decompression of the neural canal. The authors retrospectively evaluated their radiographic experience with this injury in 27 patients over a...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.163.3.3575720

    authors: Mirvis SE,Young JW,Lim C,Greenberg J

    更新日期:1987-06-01 00:00:00

  • Antiangiogenic tumor treatment: early noninvasive monitoring with USPIO-enhanced MR imaging in mice.

    abstract:PURPOSE:To prospectively investigate steady-state blood volume measurements for early quantitative monitoring of antiangiogenic treatment with ultrasmall superparamagnetic iron oxide (USPIO)-enhanced magnetic resonance (MR) imaging. MATERIALS AND METHODS:The institutional animal care committee approved all experiments...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2442060371

    authors: Persigehl T,Bieker R,Matuszewski L,Wall A,Kessler T,Kooijman H,Meier N,Ebert W,Berdel WE,Heindel W,Mesters RM,Bremer C

    更新日期:2007-08-01 00:00:00

  • The National Institute of Biomedical Imaging and Bioengineering and NIH grant process: an overview.

    abstract::The National Institutes of Health (NIH) comprise the largest single source of funding in the world for the support of biomedical research. Much of the work of the NIH focuses on the elucidation of fundamental biophysical, biochemical, and biologic aspects of the molecular, cellular, and tissue processes underlying bot...

    journal_title:Radiology

    pub_type: 杂志文章,评审

    doi:10.1148/radiol.2421051180

    authors: Wolbarst AB,Hendee WR

    更新日期:2007-01-01 00:00:00

  • Thyroid gland tumor diagnosis at US elastography.

    abstract:PURPOSE:To prospectively evaluate the elastographic appearance of thyroid gland tumors and explore the potential sensitivity and specificity of ultrasonographic (US) elastography for differentiating benign and malignant tumors, with histopathologic analysis as the reference standard. MATERIALS AND METHODS:The study wa...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2363041248

    authors: Lyshchik A,Higashi T,Asato R,Tanaka S,Ito J,Mai JJ,Pellot-Barakat C,Insana MF,Brill AB,Saga T,Hiraoka M,Togashi K

    更新日期:2005-10-01 00:00:00

  • Joint effusion in children with an irritable hip: US diagnosis and aspiration.

    abstract::Ninety-six children with an irritable hip possibly representing septic arthritis underwent clinical and laboratory evaluation, radiography, and ultrasonography (US). Forty had normal US scans; none were later shown to have septic arthritis, although three had osteomyelitis. Fifty-six children had effusion at US. Thirt...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.187.2.8475290

    authors: Zawin JK,Hoffer FA,Rand FF,Teele RL

    更新日期:1993-05-01 00:00:00

  • Neodymium yttrium aluminum garnet laser treatment of hemobilia via a percutaneous biliary catheter track.

    abstract::The authors describe the use of neodymium yttrium aluminum garnet laser introduced via a percutaneous catheter track for photocoagulation of a bleeding bile duct tumor. ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.148.3.6878710

    authors: Carpenter CM,Bowers JH,Luers PR,Dixon JA,Miller FJ

    更新日期:1983-09-01 00:00:00

  • Depiction of diaphragmatic muscle slips on supine plain radiographs: a sign of pneumoperitoneum.

    abstract:PURPOSE:To describe the diaphragm muscle slip sign, a previously unreported finding of pneumoperitoneum on plain radiographs. MATERIALS AND METHODS:Diaphragmatic muscle slips were observed on supine plain abdominal (n = 6) or recumbent frontal chest (n = 3) radiographs in nine patients. Computed tomographic (CT) confi...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.203.2.9114100

    authors: Cho KC,Baker SR

    更新日期:1997-05-01 00:00:00

  • Disparate imaging of the autonomous functioning thyroid nodule with 99mTc-pertechnetate and radioiodine.

    abstract::Four nodules, visualized with 99mTc pertechnetate at 20-60 min., were not visualized with either 123I or 131I at 2-4 hours. Each nodule was demonstrated to have autonomy of function in excess of surrounding normal tissue when imaged with radioiodine after TSH suppression. Rapid turnover of an iodine moiety would seem ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/119.3.737

    authors: Miller JM,Kasenter AG,Marks DS

    更新日期:1976-06-01 00:00:00

  • Appendicitis in children: color Doppler sonography.

    abstract::The authors used color Doppler ultrasonography (US) to evaluate 33 children with suspected appendicitis and found locally increased blood flow in all of 10 patients with appendicitis or periappendiceal abscess; the studies were normal in 16 patients without appendicitis. The gray-scale sonographic results were concord...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.184.3.1509060

    authors: Quillin SP,Siegel MJ

    更新日期:1992-09-01 00:00:00

  • Hemorrhage in intracerebral arteriovenous malformations: angiographic determinants.

    abstract::The most serious and frequent complication of intracranial arteriovenous malformations (AVMs) is intracranial hemorrhage. Identification of patients at greatest risk for intracranial bleeding would be beneficial. Detailed analysis of vascular architecture was performed in 65 patients with intracranial AVMs to identify...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.176.3.2389040

    authors: Marks MP,Lane B,Steinberg GK,Chang PJ

    更新日期:1990-09-01 00:00:00

  • Development and evaluation of a needle for percutaneous ethanol injection therapy.

    abstract::To avoid the disadvantages associated with use of the traditional percutaneous transhepatic cholangiography (PTC) needle in ultrasonically guided percutaneous ethanol injection therapy (PEIT) for hepatocellular carcinoma, the authors developed a needle with a three-sided tip and three holes within 3 mm of the tip. In ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.186.1.8416580

    authors: Akamatsu K,Miyauchi S,Ito Y,Ohkubo K,Maruyama M

    更新日期:1993-01-01 00:00:00

  • Susceptibility-weighted MR imaging in the grading of liver fibrosis: a feasibility study.

    abstract:PURPOSE:To assess the feasiblity of magnetic resonance (MR) susceptibility-weighted (SW) imaging as a tool to evaluate liver fibrosis grades in patients with chronic liver diseases (CLD) utilizing signal intensity (SI) measurements, with histopathologic findings as the reference standard. MATERIALS AND METHODS:This re...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.13122440

    authors: Balassy C,Feier D,Peck-Radosavljevic M,Wrba F,Witoszynskyj S,Kiefer B,Reiter G,Dai Y,Ba-Ssalamah A

    更新日期:2014-01-01 00:00:00

  • Imaging Biomarkers of Tumor Response in Neuroendocrine Liver Metastases Treated with Transarterial Chemoembolization: Can Enhancing Tumor Burden of the Whole Liver Help Predict Patient Survival?

    abstract::Purpose To investigate whether whole-liver enhancing tumor burden [ETB] can serve as an imaging biomarker and help predict survival better than World Health Organization (WHO), Response Evaluation Criteria in Solid Tumors (RECIST), modified RECIST (mRECIST), and European Association for the Study of the Liver (EASL) m...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2016160838

    authors: Sahu S,Schernthaner R,Ardon R,Chapiro J,Zhao Y,Sohn JH,Fleckenstein F,Lin M,Geschwind JF,Duran R

    更新日期:2017-06-01 00:00:00

  • Method to control spraying of high-velocity infected blood droplets during arterial catheterization.

    abstract::Spurting of blood from standard arterial needles during guide-wire insertion can be controlled easily with a syringe and a simple needle inserted along the syringe plunger. With this method, blood droplets that may be infected with the hepatitis or human immunodeficiency virus will not come into contact with the head ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.174.3.174-3-1055

    authors: Cope C,Machan L

    更新日期:1990-03-01 00:00:00

  • Amyloidosis of heart and liver: comparison of Tc-99m pyrophosphate and Tc-99m methylene diphosphonate for detection.

    abstract::A prospective, comparative study was made of the efficacy of technetium-99m pyrophosphate (Tc PYP) and technetium-99m methylene diphosphonate (Tc MDP) in detecting soft-tissue amyloidosis. Tc PYP and Tc MDP scans were obtained within ten-day intervals in seven patients with histologically proven amyloidosis. Tc PYP wa...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.148.1.6304810

    authors: Lee VW,Caldarone AG,Falk RH,Rubinow A,Cohen AS

    更新日期:1983-07-01 00:00:00

  • Giant gastric folds: differential diagnosis at US.

    abstract:PURPOSE:To evaluate ultrasonographic (US) features in the differential diagnosis of giant gastric folds. MATERIALS AND METHODS:One hundred sixty-five patients with giant gastric folds at transabdominal US examination (five with Ménétrier disease, 24 with anisakiasis, 61 with acute gastric mucosal lesion [AGML], 13 wit...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2263012080

    authors: Okanobu H,Hata J,Haruma K,Hara M,Nakamura K,Tanaka S,Chayama K

    更新日期:2003-03-01 00:00:00

  • Regional Mapping of Aortic Wall Stress by Using Deformable, Motion-coherent Modeling based on Electrocardiography-gated Multidetector CT Angiography: Feasibility Study.

    abstract::Purpose To investigate the feasibility of deformable, motion-coherent modeling based on electrocardiography-gated multidetector computed tomographic (CT) angiography of the thoracic aorta and to evaluate whether quantifiable information on aortic wall stress as a function of patient-specific cardiovascular parameters ...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiol.2015151078

    authors: Mileto A,Heye TJ,Makar RA,Hurwitz LM,Marin D,Boll DT

    更新日期:2016-07-01 00:00:00

  • Bone sarcomas in Paget disease.

    abstract::The most serious complication of Paget disease is the development of sarcoma. Forty-one cases of bone sarcoma in Paget disease, which represented our institution's entire experience, were reviewed. The relative frequency of sarcomatous degeneration was 0.9%. Histologically, 35 of 41 lesions were osteogenic sarcomas, a...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.146.2.6571760

    authors: Greditzer HG 3rd,McLeod RA,Unni KK,Beabout JW

    更新日期:1983-02-01 00:00:00

  • Growth of the fetal biparietal diameter in different types of pregnancies.

    abstract::A total of 24,560 fetal biparietal measurements were made using the B-scan technique. The increase in biparietal diameter was compared in normal pregnancies, in those complicated by diabetes or toxemia, and in fetuses thought to be small for dates. Only the last of these groups demonstrated a statistically significant...

    journal_title:Radiology

    pub_type: 杂志文章

    doi:10.1148/radiology.137.1.7422840

    authors: Aantaa K,Forss M

    更新日期:1980-10-01 00:00:00