Abstract:
PURPOSE:To assess computed tomography (CT) with iodized oil for depiction of small hepatocellular carcinoma (HCC) before liver transplantation. MATERIALS AND METHODS:Thirty-five consecutive cirrhotic patients underwent CT with iodized oil to determine the presence, number, size, and location of possible nodules. All patients underwent liver transplantation within 4 months after CT. Explanted livers were cut in 8-mm slices that corresponded to axial CT scan planes. Comparison between CT staging and pathologic findings was made. RESULTS:Pathologic studies showed 17 HCC nodules (diameter, 0.9-4.0 cm) in nine of the 35 livers. CT depicted nine of these 17 nodules. Lesion-by-lesion analysis revealed a sensitivity of 53%; CT falsely depicted three additional nodules not confirmed with pathologic findings. Patient-by-patient analysis revealed an 89% sensitivity and an 88% specificity. CONCLUSION:CT with iodized oil, when assessed lesion by lesion, has a low sensitivity. These results must be considered when liver resection is proposed for HCC.
journal_name
Radiologyjournal_title
Radiologyauthors
Taourel PG,Pageaux GP,Coste V,Fabre JM,Pradel JA,Ramos J,Larrey D,Domergue J,Michel H,Bruel JMdoi
10.1148/radiology.197.2.7480680subject
Has Abstractpub_date
1995-11-01 00:00:00pages
377-80issue
2eissn
0033-8419issn
1527-1315journal_volume
197pub_type
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