当前位置： SCI文献检索 > SCHIZOPHRENIA RESEARCH期刊下所有文献 > Determinants of subjective health-related quality of life (HRQoL) for patients with schizophrenia.

Determinants of subjective health-related quality of life (HRQoL) for patients with schizophrenia.

Abstract：

PURPOSE:To identify the determinants of schizophrenia-specific HRQoL levels, five types of factors (i.e., sociodemographic, clinical, psychopathological, neurocognitive, and psychosocial factors) were simultaneously investigated in the same cross-sectional sample. METHODS:A total of 120 patients with a diagnosis of schizophrenia but not spectrum conditions were recruited by convenience sampling. Subjective HRQoL levels were measured using the disease-specific S-QoL-C. After sociodemographic and clinical data were collected, psychopathological data were self-rated with the Beck Depression Inventory-II (BDI-II) and were assessed with the Positive and Negative Syndrome Scale (PANSS) by professionally trained raters. Two neurocognitive assessments were conducted by licensed occupational therapists (OTs). Psychosocial factors were assessed using self-reports measures, including the, General Self-Efficacy Scale (GSES), Rosenberg Self-Esteem Scale (RSES), and Social Impact Scale (SIS). All measures were administered in random order. OTs, PANSS raters, and participants were blinded to score computation, and multiple hierarchical regression with the stepwise method was conducted. RESULTS:The S-QoL-C scores were most strongly affected by psychosocial factors and the psychopathological factors, followed by clinical and sociodemographic factors. Total scores on the BDI-II had the largest contributions to S-QoL-C index scores and seven of eight S-QoL-C subscales. In addition, the GSES, RSES, and SIS showed effects across the S-QoL-C subscales. The BDI-II, GSES, and RSES all influenced the S-QoL-C index scores, in addition to the number of hospitalizations. CONCLUSION:Psychosocial factors and psychopathological factors measured by the BDI-II had the greatest impact on schizophrenia-specific HRQoL levels. Psychiatric treatment programs focusing on psychosocial status and depressive symptoms can improve schizophrenia-specific HRQoL levels.

journal_name

Schizophr Res

journal_title

Schizophrenia research

authors

Chou CY,Ma MC,Yang TT

doi

10.1016/j.schres.2014.02.011

subject

Has Abstract

pub_date

2014-04-01 00:00:00

pages

83-8

issue

1-3

eissn

0920-9964

issn

1573-2509

pii

S0920-9964(14)00077-2

journal_volume

154

pub_type

杂志文章

相关文献

SCHIZOPHRENIA RESEARCH文献大全
  • Schizophrenic delusions: the detection of warning signals.

    abstract：:Schizophrenic delusions are important target symptoms for treatment. This study aims to identify predictors of delusion formation. Two samples of schizophrenic patients (total n = 131) are examined prospectively every second week during a period of 6 months. In one sample (n = 60) delusion formation (n = 27; 45%) is c...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/s0920-9964(98)00033-4

    authors： Jørgensen P

    更新日期：1998-06-22 00:00:00

  • The effects of voice content on stress reactivity: A simulation paradigm of auditory verbal hallucinations.

    abstract：OBJECTIVES:Psychosis is associated with increased subjective and altered endocrine and autonomic nervous system stress-reactivity. Psychosis patients often experience auditory verbal hallucinations, with negative voice content being particularly associated with distress. The present study developed a voice-simulation p...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2019.07.019

    authors： Baumeister D,Peters E,Pruessner J,Howes O,Chadwick P

    更新日期：2019-08-01 00:00:00

  • The insula-claustrum region and delusions in schizophrenia.

    abstract：OBJECTIVE:We examined the relationship between cerebral gray matter (GM) volume and severity of delusions and hallucinations in adults with schizophrenia. METHOD:MRI scans in 43 patients with schizophrenia were acquired. Correlations were computed between GM volume and clinician ratings of hallucinations and delusions...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2011.08.004

    authors： Cascella NG,Gerner GJ,Fieldstone SC,Sawa A,Schretlen DJ

    更新日期：2011-12-01 00:00:00

  • Neighborhood crime, socioeconomic status, and suspiciousness in adolescents and young adults at Clinical High Risk (CHR) for psychosis.

    abstract：INTRODUCTION:Contextual factors representing chronic stressors, such as neighborhood crime characteristics, have been repeatedly linked to compromised mental and physical health, and may contribute to the pathologizing of normative/non-clinical experiences. However, the impact of such structural factors has seldom been...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2019.11.024

    authors： Vargas T,Rakhshan Rouhakhtar PJ,Schiffman J,Zou DS,Rydland KJ,Mittal VA

    更新日期：2020-01-01 00:00:00

  • Executive functioning in schizophrenia: the result of impairments in lower order cognitive skills?

    abstract：:Executive functioning (EF) impairments are common in schizophrenia. There are two propositions regarding the causes of these impairments: (1) executive impairments are the result of the compounding effects of deficits in lower order cognitive skills (e.g. processing speed, attention) or (2) EF impairments exist in the...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2013.07.034

    authors： Neill E,Rossell SL

    更新日期：2013-10-01 00:00:00

  • The Brief Assessment of Cognition in Schizophrenia: reliability, sensitivity, and comparison with a standard neurocognitive battery.

    abstract：:Studies of neurocognitive function in patients with schizophrenia use widely variable assessment techniques. Clinical trials assessing the cognitive enhancing effect of new medications have used neurocognitive assessment batteries that differed in content, length and administration procedures. The Brief Assessment of ...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2003.09.011

    authors： Keefe RS,Goldberg TE,Harvey PD,Gold JM,Poe MP,Coughenour L

    更新日期：2004-06-01 00:00:00

  • Analysis of differential gene expression mediated by clozapine in human postmortem brains.

    abstract：:Clozapine is the only medication indicated for treating refractory schizophrenia, due to its superior efficacy among all antipsychotic agents, but its mechanism of action is poorly understood. To date, no studies of human postmortem brain have characterized the gene expression response to clozapine. Therefore, we addr...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,meta分析

    doi：10.1016/j.schres.2016.12.017

    authors： Lee BJ,Marchionni L,Andrews CE,Norris AL,Nucifora LG,Wu YC,Wright RA,Pevsner J,Ross CA,Margolis RL,Sawa A,Nucifora FC Jr

    更新日期：2017-07-01 00:00:00

  • Comorbid posttraumatic stress disorder is associated with suicidality in male veterans with schizophrenia or schizoaffective disorder.

    abstract：:The purpose of this study was to determine if patients with schizophrenia or schizoaffective disorders and comorbid posttraumatic stress disorder (PTSD) are at higher risk for suicidality than patients without comorbid PTSD. Participants were 165 male veterans with primary diagnoses of schizophrenia or schizoaffective...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2006.02.010

    authors： Strauss JL,Calhoun PS,Marx CE,Stechuchak KM,Oddone EZ,Swartz MS,Butterfield MI

    更新日期：2006-05-01 00:00:00

  • Paternal and maternal ages have contrasting associations with self-reported schizophrenia liability.

    abstract：BACKGROUND:Older paternal age predicts schizophrenia diagnosis in offspring. If this relationship reflects a pathogenic process, paternal age should predict the expression of subclinical schizophrenia liability (schizotypy). We hypothesized that paternal and maternal ages predict positive, negative, and disorganized fe...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2015.09.018

    authors： Grattan RE,Morton SE,Warhurst ES,Parker TR,Nicolson MP,Maha JLK,Linscott RJ

    更新日期：2015-12-01 00:00:00

  • Investigation of metamemory dysfunctions in first-episode schizophrenia.

    abstract：:A number of recent studies have suggested that schizophrenia patients share metamemory deficits, particularly, a decreased ability to distinguish between errors and correct responses in terms of response confidence (i.e., decreased confidence gap): patients are over-confident in errors while at the same time being und...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2005.09.004

    authors： Moritz S,Woodward TS,Chen E

    更新日期：2006-01-31 00:00:00

  • Goal-directed planning and action impairments in schizophrenia evaluated in a virtual environment.

    abstract：:Planning and executing goal-directed behaviours are critical final steps in translating motivation into action. Amotivation is a key feature of schizophrenia, but its impact on goal-directed functioning has not been extensively studied in an objective and ecologically valid manner. To address this, we investigated goa...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2018.10.012

    authors： Siddiqui I,Saperia S,Fervaha G,Da Silva S,Jeffay E,Zakzanis KK,Agid O,Remington G,Foussias G

    更新日期：2019-04-01 00:00:00

  • A stress-coping model of mental illness stigma: I. Predictors of cognitive stress appraisal.

    abstract：:Stigma can be a major stressor for individuals with schizophrenia and other mental illnesses. It is unclear, however, why some stigmatized individuals appraise stigma as more stressful, while others feel they can cope with the potential harm posed by public prejudice. We tested the hypothesis that the level of perceiv...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2009.01.006

    authors： Rüsch N,Corrigan PW,Wassel A,Michaels P,Olschewski M,Wilkniss S,Batia K

    更新日期：2009-05-01 00:00:00

  • Schizophrenic births and viral diseases in two states.

    abstract：:In order to investigate a possible relationship between schizophrenic births and viral diseases, the birth month and year of all state hospital admissions for schizophrenia in Connecticut and Massachusetts from 1973-1974 were compared with the occurrence of reportable viral diseases for 1920-1955. Data was statistical...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/0920-9964(88)90043-6

    authors： Torrey EF,Rawlings R,Waldman IN

    更新日期：1988-01-01 00:00:00

  • Evidence for impaired mnemonic strategy use among patients with schizophrenia using the part-list cuing paradigm.

    abstract：PURPOSE:Strategic and mnemonic abilities of person with schizophrenia (SCZ) were studied using a part-list cuing (PLC) task. In this task, presentation of retrieval cues in the form of a subset of studied words typically impairs recall of the remaining items. This impairment is thought to reflect a disruption of partic...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2006.03.001

    authors： Christensen BK,Girard TA,Benjamin AS,Vidailhet P

    更新日期：2006-07-01 00:00:00

  • Clozapine directly increases insulin and glucagon secretion from islets: implications for impairment of glucose tolerance.

    abstract：:Second generation antipsychotics cause derangements in glucose metabolism that are often interpreted as insulin resistance. In previous studies we have shown that this is not classical insulin resistance but the drugs were actually inducing a hyperglycaemic state associated with elevated hepatic glucose output (HGO) a...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2014.05.003

    authors： Smith GC,Zhang ZY,Mulvey T,Petersen N,Lach S,Xiu P,Phillips A,Han W,Wang MW,Shepherd PR

    更新日期：2014-08-01 00:00:00

  • Neural correlates of reality filtering in schizophrenia spectrum disorder.

    abstract：BACKGROUND:A false sense of reality is a characteristic of schizophrenia spectrum disorders (SSD). Reality confusion may also emanate from posterior orbitofrontal cortex (OFC) lesions, as evident in confabulations that patients act upon and disorientation. This confusion can be measured by repeated runs of a continuous...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2018.07.036

    authors： Thézé R,Manuel AL,Pedrazzini E,Chantraine F,Patru MC,Nahum L,Guggisberg AG,Schnider A

    更新日期：2019-02-01 00:00:00

  • The components of executive functioning in a cohort of patients with chronic schizophrenia: a multiple single-case study design.

    abstract：:We examined the fractionation of executive functioning performance in ninety patients with schizophrenia, who were tested for initiation, sustained attention, switching/flexibility, attention allocation and impulsivity/disinhibition. The participants were also given tests of general intelligence and memory. We analyse...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2005.08.011

    authors： Chan RC,Chen EY,Cheung EF,Chen RY,Cheung HK

    更新日期：2006-01-31 00:00:00

  • Neighborhood-level predictors of age at onset and duration of untreated psychosis in first-episode psychotic disorders.

    abstract：OBJECTIVE:Recent years have witnessed growing interest in the role of the social environment in the development and outcomes of schizophrenia. We investigated whether neighborhood characteristics are associated with two important prognostic factors in early-course psychosis, age at onset of psychosis (AOP) and duration...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2019.12.036

    authors： Ku BS,Pauselli L,Manseau M,Compton MT

    更新日期：2020-04-01 00:00:00

  • Trait or state? A longitudinal neuropsychological evaluation and fMRI study in schizoaffective disorder.

    abstract：:Schizoaffective patients can have neurocognitive deficits and default mode network dysfunction while being acutely ill. It remains unclear to what extent these abnormalities persist when they go into clinical remission. Memory and executive function were tested in 22 acutely ill schizoaffective patients; they also und...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2014.08.017

    authors： Madre M,Radua J,Landin-Romero R,Alonso-Lana S,Salvador R,Panicali F,Pomarol-Clotet E,Amann BL

    更新日期：2014-11-01 00:00:00

  • Health-related quality of life in acute schizophrenia patients treated with RBP-7000 once monthly risperidone: An 8-week, randomized, double-blind, placebo-controlled, multicenter phase 3 study.

    abstract：BACKGROUND:There is increased interest in the impact of new long-acting treatments on health-related quality of life (HRQoL) in patients with schizophrenia. The aim of this study was to evaluate the impact of treatment with subcutaneous injections of RBP-7000, a new sustained-release formulation of risperidone, compare...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,多中心研究,随机对照试验

    doi：10.1016/j.schres.2016.03.020

    authors： Isitt JJ,Nadipelli VR,Kouassi A,Fava M,Heidbreder C

    更新日期：2016-07-01 00:00:00

  • Glutamate in schizophrenia: Neurodevelopmental perspectives and drug development.

    abstract：:Research into the neurobiological processes that may lead to the onset of schizophrenia places growing emphasis on the glutamatergic system and brain development. Preclinical studies have shown that neurodevelopmental, genetic, and environmental factors contribute to glutamatergic dysfunction and schizophrenia-related...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,评审

    doi：10.1016/j.schres.2020.09.013

    authors： Egerton A,Grace AA,Stone J,Bossong MG,Sand M,McGuire P

    更新日期：2020-09-01 00:00:00

  • Increased interleukin-2 serum levels were associated with psychopathological symptoms and cognitive deficits in treatment-resistant schizophrenia.

    abstract：:Accumulating evidence showed that interleukin-2 (IL-2) may be involved in the pathophysiology of schizophrenia. Increased IL-2 levels have been found in the serum of schizophrenia patients with mixed results. In the present study, we assessed serum IL-2 levels in a large group of 160 schizophrenia patients compared to...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2015.10.038

    authors： Tan Y,Li Y,Tan S,Wang Z,Yang FD,Cao B,Zunta-Soares GB,Soares JC,Zhang XY

    更新日期：2015-12-01 00:00:00

  • Autoimmune diseases, gastrointestinal disorders and the microbiome in schizophrenia: more than a gut feeling.

    abstract：:Autoimmunity, gastrointestinal (GI) disorders and schizophrenia have been associated with one another for a long time. This paper reviews these connections and provides a context by which multiple risk factors for schizophrenia may be related. Epidemiological studies strongly link schizophrenia with autoimmune disorde...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,评审

    doi：10.1016/j.schres.2014.06.027

    authors： Severance EG,Yolken RH,Eaton WW

    更新日期：2016-09-01 00:00:00

  • Comparison of the effectiveness of Conners' CPT and the CPT-identical pairs at distinguishing between smokers and nonsmokers with schizophrenia.

    abstract：:Sustained attention deficits and high rates of smoking are often observed in patients with schizophrenia. This has led to the hypothesis that patients may smoke as an attempt to ameliorate cognitive deficits related to abnormal nicotinic structure and function. Continuous performance tasks (CPT) are often used to inde...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2013.06.012

    authors： Roth M,Hong LE,McMahon RP,Fuller RL

    更新日期：2013-08-01 00:00:00

  • Increase in serum HDL level is associated with less negative symptoms after one year of antipsychotic treatment in first-episode psychosis.

    abstract：BACKGROUND:A potential link between increase in total cholesterol and triglycerides and clinical improvement has been observed during antipsychotic drug treatment in chronic schizophrenia patients, possibly due to drug related effects on lipid biosynthesis. We examined whether changes in serum lipids are associated wit...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2017.10.042

    authors： Gjerde PB,Dieset I,Simonsen C,Hoseth EZ,Iversen T,Lagerberg TV,Lyngstad SH,Mørch RH,Skrede S,Andreassen OA,Melle I,Steen VM

    更新日期：2018-07-01 00:00:00

  • A confirmatory factor analytic evaluation of the pentagonal PANSS model.

    abstract：:The positive and negative syndrome scale (PANSS) is widely used in psychiatric research. Reflecting this common use, considerable attention has been applied to the psychometric properties of this instrument. However, despite the publication of numerous studies and analyses, it remains uncertain how best data from the ...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/s0920-9964(02)00295-5

    authors： Fitzgerald PB,de Castella AR,Brewer K,Filia K,Collins J,Davey P,Rolfe T,Kulkarni J

    更新日期：2003-05-01 00:00:00

  • Sexually dimorphic subcortical brain volumes in emerging psychosis.

    abstract：BACKGROUND:In schizophrenic psychoses, the normal sexual dimorphism of the brain has been shown to be disrupted or even reversed. Little is known, however, at what time point in emerging psychosis this occurs. We have therefore examined, if these alterations are already present in the at-risk mental state (ARMS) for ps...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2018.03.034

    authors： Egloff L,Lenz C,Studerus E,Harrisberger F,Smieskova R,Schmidt A,Huber C,Simon A,Lang UE,Riecher-Rössler A,Borgwardt S

    更新日期：2018-09-01 00:00:00

  • Comparison of metabolic effects of aripiprazole, quetiapine and ziprasidone after 12 weeks of treatment in first treated episode of psychosis.

    abstract：:This randomized open-label study compared the incidence of metabolic side effects of aripiprazole, ziprasidone and quetiapine in a population of medication-naïve first-episode psychosis patients. A total of 202 subjects were enrolled. Body weight, body mass index, leptin, fasting lipids and fasting glycaemic parameter...

    journal_title：Schizophrenia research

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.schres.2014.07.045

    authors： Pérez-Iglesias R,Ortiz-Garcia de la Foz V,Martínez García O,Amado JA,Garcia-Unzueta MT,Ayesa-Arriola R,Suarez-Pinilla P,Tabares-Seisdedos R,Crespo-Facorro B

    更新日期：2014-10-01 00:00:00

  • Outcome after discharge from an early psychosis program.

    abstract：:Studies defining the course and outcome of individuals experiencing their first episode (FE) of psychosis generally report an improvement in symptoms and functioning. Today, many FE patients are treated in specialized early psychosis programs. Little is known what happens to these individuals after discharge from thes...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2008.08.032

    authors： Addington J,Addington D

    更新日期：2008-12-01 00:00:00

  • A new measure of authentic auditory emotion recognition: Application to patients with schizophrenia.

    abstract：BACKGROUND:Many social processes such as emotion recognition are severely impaired in patients with schizophrenia. While basic auditory processing seems to play a key role in identifying emotions, research in this field is limited due to the lack of proper assessment batteries. Many of the widely accepted tests utilize...

    journal_title：Schizophrenia research

    pub_type： 杂志文章

    doi：10.1016/j.schres.2019.11.043

    authors： Chaturvedi R,Kraus M,Keefe RSE

    更新日期：2020-08-01 00:00:00