Abstract：
:The influence of two kinds of transplantable melanomas on the secretory function of peritoneal macrophages, and particularly the release of TNF-alpha has been studied. The results showed a statistically significant increase of protein content in the supernatants from 24 h cultured macrophages from melanoma-bearing hamsters in comparison with control macrophages. The release of TNF-alpha by control macrophages was higher than that by macrophages of hamsters with transplantable melanomas. The decrease in release of this factor was more prominent in case of macrophages from hamsters bearing amelanotic melanoma, it may suggest that biological features of melanomas can influence peritoneal macrophages to release the TNF-alpha at different level.
journal_name
Neoplasmajournal_title
Neoplasmaauthors
Kozłowska K,Cichorek Msubject
Has Abstractpub_date
1995-01-01 00:00:00pages
75-8issue
2eissn
0028-2685issn
1338-4317journal_volume
42pub_type
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