Abstract：
:In 41 patients with Hodgkin's disease nitroblue tetrazolium (NBT) dye reduction with resting and stimulated granulocytes, before, in the course and after chemotherapy was examined. Twofold decrease of the capability of NBT reduction test with stimulated granulocytes was found, whereas with resting granulocytes only slight diminution was noted. Chemotherapy did not improve the tested parameters. No relationship was observed between the stage of disease and the presence of systemic symptoms and the NBT dye reduction. It can be assumed that granulocytes from patients with Hodgkin's disease are resistant to stimulation. The observations suggest that NBT test may be useful for evaluation of the function of granulocytes and to some extent for monitoring of the chemotherapy.
journal_name
Neoplasmajournal_title
Neoplasmaauthors
Kemona H,Wysocka J,Prokopowicz J,Kiluk Ssubject
Has Abstractpub_date
1987-01-01 00:00:00pages
107-13issue
1eissn
0028-2685issn
1338-4317journal_volume
34pub_type
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