Effect of 2-amino-4-phosphonobutyrate on ERG OFF-response after glycinergic and GABAergic blockade.


:Superfusion with 200 microM 2-amino-4-phosphonobutyrate (APB) of dark and chromatically adapted frog eyecups caused marked potentiation of the ERG OFF-response (d-wave). Blockade of the glycinergic synapses by strychnine did not change this effect at all. Blockade of the GABAergic synapses by picrotoxin slightly diminished the effect of APB in chromatically-adapted eyes with isolated cones' activity, and did not change it in dark-adapted eyes. The results indicate that the action of APB on ERG OFF-response does not depend significantly on GABAergic and glycinergic neurotransmission in frog retina.


Vision Res


Vision research


Popova E,Kupenova P,Vitanova L,Mitova L




Has Abstract


1995-07-01 00:00:00














  • Effects of biased feedback on learning and deciding in a vernier discrimination task.

    abstract::We investigate the influence of biased feedback on decision and learning processes in a vernier discrimination task. Subjects adjust their decision criteria and hence their responses according to biased external feedback. However, they do not use learning processes to encode incorrectly classified stimuli. As soon as ...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Herzog MH,Fahle M

    更新日期:1999-01-01 00:00:00

  • Failure of rivalry at low contrast: evidence of a suprathreshold binocular summation process.

    abstract::Presentation of different images to the two eyes normally results in a time-varying alternation between the two images (binocular rivalry). However, we find that when orthogonal gratings are viewed dichoptically at low contrast, a stable summation between the two images is perceived in the form of a dichoptic plaid. T...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Liu L,Tyler CW,Schor CM

    更新日期:1992-08-01 00:00:00

  • Dynamic accommodation with simulated targets blurred with high order aberrations.

    abstract::High order aberrations have been suggested to play a role in determining the direction of accommodation. We have explored the effect of retinal blur induced by high order aberrations on dynamic accommodation by measuring the accommodative response to sinusoidal variations in accommodative demand (1-3D). The targets we...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Gambra E,Wang Y,Yuan J,Kruger PB,Marcos S

    更新日期:2010-09-15 00:00:00

  • Summation of texture segregation across orientation and spatial frequency: electrophysiological and psychophysical findings.

    abstract::Objects are usually segregated from ground by several visual dimensions. We studied texture segregation in checkerboards defined by gradients in spatial frequency, orientation or both frequency and orientation, using Gabor-filtered noise patterns. Saliency was measured electrophysiologically using the visual evoked po...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Bach M,Schmitt C,Quenzer T,Meigen T,Fahle M

    更新日期:2000-01-01 00:00:00

  • Enhanced transduction and improved photoreceptor survival of retinal degeneration by the combinatorial use of rAAV2 with a lower dose of adenovirus.

    abstract::Recombinant adeno-associated virus (rAAV) is widely used in retinal gene therapy. Enhanced rAAV transduction may be important for better therapeutic effects in some retinal gene therapies. In this study, we examined the effects of adenovirus 5 (Ad5) on retina transduction mediated by rAAV2. Our results provide the fir...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Wu J,Zhang S,Wu X,Dong X,Xu P,Liu X,Li C,Huang Q

    更新日期:2008-07-01 00:00:00

  • Perceptual learning of Vernier discrimination transfers from high to zero noise after double training.

    abstract::Perceptual learning is often interpreted as learning of fine stimulus templates. However, we have proposed that perceptual learning is more than template learning, in that more abstract statistical rules may have been learned, so that learning can transfer to stimuli at different precisions. Here we provide new eviden...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Xie XY,Yu C

    更新日期:2019-03-01 00:00:00

  • Modeling the dynamics of light adaptation: the merging of two traditions.

    abstract::Light adaptation has been studied using both aperiodic and periodic stimuli. Two well-documented phenomena are described: the background-onset effect (from an aperiodic-stimulus tradition) and high-temporal-frequency linearity (from the periodic-stimulus tradition). These phenomena have been explained within two diffe...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Graham N,Hood DC

    更新日期:1992-07-01 00:00:00

  • Dynamic noise backgrounds facilitate target fading.

    abstract::With strict fixation, a small uniform target of medium contrast, placed at 10 deg eccentricity, faded much faster when presented on a dynamic random noise background than on either a static random noise background or a uniform background of the same luminance. Time to first disappearance was between 10 and 16 sec when...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Spillmann L,Kurtenbach A

    更新日期:1992-10-01 00:00:00

  • The effect of 3D structure on motion segmentation.

    abstract::A smooth surface imaged on the retina produces a smooth flow field. Thus, the visual system may group regions of smoothly varying flow to segment surfaces. We tested this idea by having observers perform a segmentation task on several stimuli that differed in their 3D interpretations but were all matched in the smooth...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Bravo MJ,Farid H

    更新日期:2000-01-01 00:00:00

  • Offset dynamics of human smooth pursuit eye movements: effects of target presence and subject attention.

    abstract::Subjects made smooth pursuit eye movements with a target moving horizontally at 15 deg/sec. At a specified location the target either: (1) suddenly vanished; or (2) jumped to the fovea with target retinal velocity and feedback becoming 0 (target stabilized at the fovea). In each type of trial, the subjects either: "lo...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Pola J,Wyatt HJ

    更新日期:1997-09-01 00:00:00

  • Photoperiod, early post-natal eye growth, and visual deprivation.

    abstract::(1) We studied the influence of photoperiod and unilateral lid suture on post-natal ocular growth in two types of White Leghorn chicks previously reported to respond differently to visual deprivation, Truslow and Cornell K chicks. We analyzed the chicks after 2 weeks of rearing, a time period commonly used in neuropha...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Stone RA,Lin T,Desai D,Capehart C

    更新日期:1995-05-01 00:00:00

  • Identification of novel retinal target genes of thyroid hormone in the human WERI cells by expression microarray analysis.

    abstract::Using the human WERI-Rb1 cell line as a model system, we performed a genome-wide search for retinal target genes of thyroid hormone (TH) via expression microarray analysis followed by quantitative real-time RT-PCR verification. We identified 12 novel retinal targets of TH, including 10 up-regulated genes (OPN1MW, OPN1...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Liu Y,Fu L,Chen DG,Deeb SS

    更新日期:2007-08-01 00:00:00

  • Visual persistence of stereoscopic stimuli: electric brain activity without perceptual correlate.

    abstract::Dynamic random-dot stereograms (RDS) were used to study cortical neuronal mechanisms related to visual persistence in nine subjects. Electric brain potential components evoked by stereoscopic stimuli were compared to those evoked by conventional checkerboard stimuli with contrast borders. In a pattern-onset/offset pre...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Skrandies W

    更新日期:1987-01-01 00:00:00

  • Interaction of first- and second-order signals in the extraction of global-motion and optic-flow.

    abstract::The intention of this series of experiments was to determine the extent to which the pathways sensitive to first-order and second-order motion are independent of one another at, and above, the level of global motion integration. We used translational, radial and rotational motion stimuli containing luminance-modulated...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Aaen-Stockdale C,Ledgeway T,McGraw P,Hess RF

    更新日期:2012-09-01 00:00:00

  • Predicting the psychophysical similarity of faces and non-face complex shapes by image-based measures.

    abstract::Shape representation is accomplished by a series of cortical stages in which cells in the first stage (V1) have local receptive fields tuned to contrast at a particular scale and orientation, each well modeled as a Gabor filter. In succeeding stages, the representation becomes largely invariant to Gabor coding (Kobata...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Yue X,Biederman I,Mangini MC,Malsburg Cv,Amir O

    更新日期:2012-02-15 00:00:00

  • Sensory loss due to object formation.

    abstract::The precision to locate individual features in depth can often be improved by integrating information over space. However, this integration can sometimes be extremely detrimental, as for example in the case of the Westheimer-McKee phenomenon where features are grouped to form an object. We replicate here the known los...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Mamassian P,Zannoli M

    更新日期:2020-09-01 00:00:00

  • Transparent motion from feature- and luminance-based processes.

    abstract::The apparent motion of a discretely displaced complex waveform with a periodic contrast modulation or "beat" of frequency f and sinusoidal components of frequencies 3f and 4f was examined at various interstimulus intervals (ISIs). At short ISIs perception of motion of both the beat and an aliased component of the wave...

    journal_title:Vision research

    pub_type: 信件


    authors: Hammett ST,Ledgeway T,Smith AT

    更新日期:1993-05-01 00:00:00

  • Why we need reading-glasses before a zimmer-frame.

    abstract::Accommodative loss represents the fastest human biological decrement. Why? To examine this, the shape of the eye-lens during accommodation or its relaxation is analysed with special reference to age-related changes. The capsule is viewed as a force transmitter: the distribution of forces along centripetal capsular arc...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Weale RA

    更新日期:2000-01-01 00:00:00

  • Isoluminant stimuli may not expose the full contribution of color to visual functioning: spatial contrast sensitivity measurements indicate interaction between color and luminance processing.

    abstract::Visual performance is greatly impaired when tested with heterochromatic isoluminant stimuli. It is thus concluded that the chromatic system contribution to many visual tasks is limited. We suggest that unless color and luminance are shown to be processed independently, such experiments do not demonstrate shortcomings ...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Gur M,Akri V

    更新日期:1992-07-01 00:00:00

  • Global motion perception: interaction of the ON and OFF pathways.

    abstract::A number of experiments were conducted to investigate the interaction of the ON and OFF pathways in the processing of global-motion signals. The stimulus employed was a variant of that used by Newsome and Pare [(1988) Journal of Neuroscience, 8, 2201-2211] in which a small subset of dots move in a common (global-motio...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Edwards M,Badcock DR

    更新日期:1994-11-01 00:00:00

  • Different effects from spatial frequency masking in texture segregation and texton detection tasks.

    abstract::The paper reports psychophysical experiments set up to study the visual cues used in texture discrimination. In particular, the special role of "textons", i.e. distinct visual features such as blobs of different size, lines at different orientation, line intersections ("crossings") and line ends ("terminators") which ...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Nothdurft HC

    更新日期:1991-01-01 00:00:00

  • The role of feedback in learning a vernier discrimination task.

    abstract::We compare improvement through training in vernier acuity under different feedback conditions in order to clarify the role of feedback during learning of a perceptual task and to test different (neural network) models of perceptual learning. Improvement of performance is measured in 49 observers under feedback, no fee...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Herzog MH,Fahle M

    更新日期:1997-08-01 00:00:00

  • Adaptation-induced alteration of the relation between response amplitude and contrast in cat striate cortical neurones.

    abstract::The activity of neurones in cat striate cortex in response to laterally moving sinusoidal gratings has been examined. The effect of prolonged visual stimulation with a high contrast moving grating stimulus of optimal orientation and spatial frequency was investigated in terms of the changes wrought in the relationship...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Dean AF

    更新日期:1983-01-01 00:00:00

  • Speeding rod recovery improves temporal resolution in the retina.

    abstract::The temporal resolution of the visual system progressively increases with light intensity. Under scotopic conditions, temporal resolution is relatively poor, and may be limited by both retinal and cortical processes. Rod photoresponses themselves are quite slow because of the slowly deactivating biochemical cascade ne...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Fortenbach CR,Kessler C,Peinado Allina G,Burns ME

    更新日期:2015-05-01 00:00:00

  • Successive episodes produce direction contrast effects in motion perception.

    abstract::Motion coherence thresholds decline with an increase in the number of frames in a random dot kinematogram (RDK), indicating that motion information can be integrated across successive frames. We investigated whether such temporal integration would be disrupted by a brief interval (32-600 msec) inserted into a motion s...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Raymond JE,Isaak M

    更新日期:1998-02-01 00:00:00

  • The flash-lag effect is reduced when the flash is perceived as a sensory consequence of our action.

    abstract::The flash-lag effect (FLE) is defined as an error in localization that consists of perceiving a flashed object to lag behind a moving one when both are presented in physical alignment. Previous studies have addressed the question if it is the predictability of the flash, or the moving object, that modulates the amount...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: López-Moliner J,Linares D

    更新日期:2006-06-01 00:00:00

  • Perceptual learning as a possible new approach for remediation and prevention of developmental dyslexia.

    abstract::Learning to read is extremely difficult for about 10% of children across cultures because they are affected by developmental dyslexia (DD). According to the dominant view, DD is considered an auditory-phonological processing deficit. However, accumulating evidence from developmental and clinical vision science, sugges...

    journal_title:Vision research

    pub_type: 杂志文章,评审


    authors: Gori S,Facoetti A

    更新日期:2014-06-01 00:00:00

  • Evidence for the stochastic independence of the blue-yellow, red-green and luminance detection mechanisms revealed by subthreshold summation.

    abstract::We investigated the manner in which the outputs of the three postreceptoral mechanisms (red-green, blue-yellow and luminance) combine to determine contrast threshold. We used a subthreshold summation paradigm to test whether the combination of the postreceptoral mechanism outputs could be described by a probability su...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Mullen KT,Sankeralli MJ

    更新日期:1999-02-01 00:00:00

  • Stimulus specificity in spatially-extended interocular suppression.

    abstract::In typical binocular rivalry demonstrations, disparate images presented in corresponding locations to the two eyes are found to alternate perceptually over time. Alternation in perception can occur even if the images presented to the two eyes do not overlap, if they are sufficiently close in space. This implies a spat...

    journal_title:Vision research

    pub_type: 杂志文章,随机对照试验


    authors: Nichols DF,Wilson HR

    更新日期:2009-07-01 00:00:00

  • Attentional selection in judgments of stereo depth.

    abstract::Stereoscopic depth is most useful when it comes from relative rather than absolute disparities. However, the depth perceived from relative disparities can vary with stimulus parameters that have no connection with depth or are irrelevant to the task. We investigated observers' ability to judge the stereo depth of task...

    journal_title:Vision research

    pub_type: 杂志文章


    authors: Farell B,Ng CJ

    更新日期:2019-05-01 00:00:00