Abstract:
:Patients with prostatic carcinoma were randomised to treatment with surgical castration (n = 47) or oral oestrogen therapy (n = 53). The oestrogen-treated patients received oral ethinyl oestradiol daily, 1 mg for the first 2 weeks followed by 150 micrograms. In addition, oestrogen was given intramuscularly as polyoestradiol phosphate monthly 160 mg for 3 months, continued by 80 mg. Before and 1 year after therapy systolic arm and toe blood pressures were measured. Eleven percent of the patients in the oestrogen group had a pathological pressure difference between the arm and toe before treatment versus 34% in the orchidectomy group. Despite the greater proportion of subclinical atherosclerotic disease in the legs of the patients in the orchidectomy group, the patients in the oestrogen group only had signs and symptoms of a deterioration of the arterial system. Thus, in the oestrogen group the arm-toe blood pressure difference increased from 20 +/- 3 to 32 +/- 4 mm Hg (p < 0.001) and the proportion of pathological toe pressures increased from 11 to 29% (p = 0.0014). Two of the patients in this group had to be referred for reconstructive surgery due to severe intermittent claudication. In addition, 5 more patients in this group suffered arterial ischemic events in the coronary and cerebral vasculatures. In contrast, there were no clinical ischemic events in the orchidectomy group and no change in the blood pressure difference between the arm and toe 1 year after orchidectomy. In conclusion, oral oestrogen therapy, in contrast to orchidectomy, induces a deterioration of the arterial supply to the lower limbs during the 1st year of therapy.(ABSTRACT TRUNCATED AT 250 WORDS)
journal_name
Urol Intjournal_title
Urologia internationalisauthors
Henriksson P,Linde Bdoi
10.1159/000282639subject
Has Abstractpub_date
1994-01-01 00:00:00pages
74-8issue
2eissn
0042-1138issn
1423-0399journal_volume
53pub_type
临床试验,杂志文章,随机对照试验abstract::Carcinoembryonic antigen (CEA) is elevated in urine and/or serum of patients with transitional cell carcinoma (TCC) of the urinary bladder. A group of 26 patients with TCC of the urinary bladder were evaluated with regard to urine/serum CEA levels and CEA tissue content. CEA could be detected in normal, metaplastic an...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280875
更新日期:1983-01-01 00:00:00
abstract:PURPOSE:To assess MRI/Transrectal Ultrasound (TRUS) fusion three-dimensional model-guided targeted biopsy (3D-Tb) versus TRUS-guided systematic biopsy (Sb) in detecting overall and high-Gleason-score (≥7) prostate cancer (PCa). METHODS:Pubmed and Web of science were searched. Studies with men having a suspicious lesio...
journal_title:Urologia internationalis
pub_type: 杂志文章,meta分析,评审
doi:10.1159/000484144
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to evaluate the effect of phallic stretch on bulbous urethral stricture while performing retrograde urethrography (RUG). METHODS:Between July 2009 and June 2012, 197 adult males with stricture pattern on uroflowmetry underwent RUG. Two films were taken, first without (film A) an...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000353228
更新日期:2014-01-01 00:00:00
abstract:BACKGROUND:Prostate cancer is a prominent form of cancer diagnosed in men living in developed countries, for which radical prostatectomy is a common frontline treatment. The aim of this systematic review was to determine whether robot-assisted laparoscopic radical prostatectomy (RALP) is more effective in the treatment...
journal_title:Urologia internationalis
pub_type: 杂志文章,评审
doi:10.1159/000435861
更新日期:2016-01-01 00:00:00
abstract::A total of 51 consecutive female patients with genuine stress incontinence who underwent a Burch or Stamey operation were clinically and urodynamically evaluated preoperatively at least 8 months postoperatively. Our study group consisted of 27 women who underwent the Burch colposuspension and 24 who had the Stamey end...
journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000282803
更新日期:1996-01-01 00:00:00
abstract::The rate of recurrence after internal urethrotomy a.m. Sachse was studied in a prospective, consecutive, randomized series of 43 patients using short-term (1 day) and long-term (14 days) postoperative catheter treatment. No significant difference was found between the two groups according to voiding interview, flowmet...
journal_title:Urologia internationalis
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1159/000280991
更新日期:1984-01-01 00:00:00
abstract::A 63-year-old man with primary malignant lymphoma of the prostate is presented. The patient underwent total cystoprostatectomy and ileal conduit construction. The specimen revealed malignant lymphoma, diffuse small cleaved cell of the gland. Three months after the operation, local recurrence and enlarged lymph node de...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282216
更新日期:1991-01-01 00:00:00
abstract:BACKGROUND:The principle of treating male infertility in those with chromosomal aberrations should change according to progress in treatment modalities. METHODS:In this study, ten patients with Robertsonian translocation were assessed for their cytogenetic and clinical characteristics to establish guidelines for treat...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000066122
更新日期:2002-01-01 00:00:00
abstract:OBJECTIVE:To assess the efficacy of transobturator tape (TOT) in the management of stress urinary incontinence at a medium term follow-up. METHODS:TOT is a polypropylene tape positioned through the obturator foramen. 70 patients with type II urinary stress incontinence were treated with TOT between June 2003 and May 2...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000127340
更新日期:2008-01-01 00:00:00
abstract::We report 2 cases of epidermoid cysts of the testis in Klinefelter's syndrome. The literature is reviewed and the relationship between Klinefelter's syndrome and epidermoid cyst of the testis is discussed. ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282003
更新日期:1987-01-01 00:00:00
abstract::The identification and diagnosis of thyroid metastases from renal adenocarcinoma are rare in living patients, though more frequent during autopsy. A case is reported in which the identification of thyroid metastases indicated a clear-cell renal carcinoma in a kidney treated 12 years earlier for emptying of multiple cy...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281389
更新日期:1988-01-01 00:00:00
abstract::Curative treatment of bladder cancer is limited to superficial tumors (Ta-T2). Advanced stages (T3a + T3b) can be treated only palliatively even when confined to the bladder (N0, M0). Nevertheless the differentiation between curable and incurable tumors is difficult. The classification of patients into the two differe...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281064
更新日期:1985-01-01 00:00:00
abstract:OBJECTIVE:Current reports suggest the presence of androgen receptor (AR) defects in prostate cancer. We have detected the AR mRNA in normal, benign hypertrophied (BPH) and carcinomatous (CaP) prostate tissues and evaluated the difference in the level of AR transcript in these groups. MATERIALS AND METHODS:Cytoplasmic ...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000283069
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Afferents from the urinary tract transmit bladder sensations to the central nervous system. Spinal cord injury (SCI) may affect both efferent motor and afferent sensory pathways. Presence/absence of bladder sensations in patients with complete spinal cord, conus or cauda equina lesions was compared with neur...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000342815
更新日期:2012-01-01 00:00:00
abstract::A 63-year-old man underwent inguinal orchiectomy for painless enlargement of the left testis. The diagnosis of malignant gonadal stromal tumor was made on the basis of morphology and immunohistochemical studies. At computed tomography there was bulky retroperitoneal metastasis. The patient then underwent retroperitone...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000283061
更新日期:1997-01-01 00:00:00
abstract::Bladder tumors were staged preoperatively before and/or after M-VEC poly-chemotherapy using transrectal ultrasonography and magnetic resonance imaging in 46 patients. The resultant findings were each compared with histomorphologic results. The sensitivity of both methods compared with pathohistology was 88%. Using thi...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282472
更新日期:1993-01-01 00:00:00
abstract:INTRODUCTION:β-HCG has been the only tumor marker evaluated in testicular vein (VT) blood until now. OBJECTIVE:To evaluate the correlation between the tumor markers β-HCG, AFP, PLAP, and LDH from the VT and peripheral blood as well as their significance in predicting tumor recurrence and tumor stage. METHODS:Patients...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000511649
更新日期:2020-12-17 00:00:00
abstract::Under standardized conditions, simultaneous urethrocystometry and recording of urethral pressure profile were performed in 10 healthy volunteers and 20 patients suffering from urge incontinence. In the normal subjects, desire to void occurred at a bladder volume of about 300 cm3. At maximum bladder capacity (approxima...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280116
更新日期:1977-01-01 00:00:00
abstract::The present study deals with morphological changes during erection both in the penile deep artery supplying the corpus cavernosum and in veins draining it. These vessels were shown to maintain wide lumina in the flaccid state. In the erect state induced by injection of papaverine, the postcavernous venules were compre...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000281341
更新日期:1988-01-01 00:00:00
abstract::The measurement of sodium and water loss after relieve of the obstruction shows that the obstructive nephropathy originates in three pathogenetic mechanisms. (1) Acute complete bilateral ureteric obstruction causes tubular atrophy, prevents both resorption and glomerular filtration, reduces the renal blood flow and in...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000280270
更新日期:1979-01-01 00:00:00
abstract::Idiopathic scrotal calcinosis is a rare, benign condition characterized by progressive calcification of the scrotal skin. A 29-year-old man who had undergone primary surgical excision of idiopathic scrotal calcinosis 7 years previously presented with recurrence that he had first noticed 3 years after surgery. Multiple...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000350240
更新日期:2014-01-01 00:00:00
abstract::We report on a unique-sized large leiomyoma of the bladder wall in a male patient. After open surgical intervention all symptoms resolved spontaneously and no relapse occurred within a 3-year follow-up period. In conclusion, for symptomatic leiomyoma of the bladder surgical intervention should be considered as an earl...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030317
更新日期:1998-01-01 00:00:00
abstract::The ability of three compounds, all similar in chemical structure to citric acid, to decrease calcium crystalluria has been measured. The measurements were made in normal human urine at 37 degrees C and compared with the crystal-decreasing power of citric acid when measured in the same way and in the same urine sample...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000282875
更新日期:1996-01-01 00:00:00
abstract::A case of spontaneous, partial, unilateral thrombosis of the corpus cavernosum is described. A 35-year-old white male presented with a painful mass in the perineum without priapism. Diagnostic evaluation with sonography and magnetic resonance imaging revealed a thrombosis in the left posterior corporal body. Treatment...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000030246
更新日期:1998-01-01 00:00:00
abstract:INTRODUCTION:The urinary bladder is commonly involved in pelvic malignancy. The incidence of apparent extension into adjacent organs in locally advanced colorectal malignancy is 5-12%. It is not known with other pelvic malignancy. No guidelines are available for its management. Often a dilemma exists between cystectomy...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000092929
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVES:To review the incidence of healthcare-associated infections/urinary tract infection (UTI), risk factors, microorganisms isolated and antibiotic resistances in patients who underwent lower urinary tract endoscopic surgery (LUTES) in a tertiary care hospital. METHODS:A prospective observational study was carr...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000488251
更新日期:2018-01-01 00:00:00
abstract:INTRODUCTION:The aim of this study is to evaluate the effect of the gonadal biopsy procedure on fertility and histology of the experimentally created undescended testis. MATERIALS AND METHODS:Thirty Wistar-Albino rat litters were divided into three groups. In the first two groups, undescended testes were obtained by d...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000087799
更新日期:2005-01-01 00:00:00
abstract:INTRODUCTION:The percentage of positive prostate biopsy cores (%PBC) has been shown to be a prognostic factor in localized prostate cancer. We hypothesized that it would predict time to hormonal independence and survival in prostate cancer patients treated with androgen deprivation therapy (ADT). PATIENTS AND METHODS:...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000230017
更新日期:2009-01-01 00:00:00
abstract::Sperm-specific glyceraldehyde 3-phosphate dehydrogenase (GAPDS) originates from spermatogenic cells of the human testis. A strong staining of GAPDS was detected in epididymal epithelium, especially in principal cells and basal cells of the epithelium. GAPDS also bound to the fibrous sheet of the sperm tail and inhibit...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000345629
更新日期:2013-01-01 00:00:00
abstract::The present study was undertaken to analyze the changes in neuroendocrine cells of the human prostate induced by neoplasms and the effect of hormonal treatment. Samples of human prostate (n = 47) were obtained during surgery or removal of organs for transplantation. The cases analyzed represent normal prostates (n = 4...
journal_title:Urologia internationalis
pub_type: 杂志文章
doi:10.1159/000283051
更新日期:1997-01-01 00:00:00