The many guises of amyloidosis. Clinical presentations and disease associations.

Abstract:

:Amyloidosis occurs in association with many diseases and can also be idiopathic. It is usually a systemic disease with variable presentations. The diagnosis should be suspected in patients with unexplained proteinuria, cardiomyopathy, congestive heart failure, peripheral neuropathy, carpal tunnel syndrome, macroglossia, or hepatosplenomegaly. Amyloidosis generally has a poor prognosis and responds poorly to therapy. Much needs to be learned about its pathogenesis and treatment possibilities.

journal_name

Postgrad Med

journal_title

Postgraduate medicine

authors

Vogelgesang SA,Klipple GL

subject

Has Abstract

pub_date

1994-10-01 00:00:00

pages

119-22, 126-7

issue

5

eissn

0032-5481

issn

1941-9260

journal_volume

96

pub_type

杂志文章,评审
  • Practicing effective preventive medicine. Pharmacologic interventions in coronary heart disease.

    abstract::Epidemiologic and clinical evidence clearly documents the relationship between elevated levels of low-density lipoprotein cholesterol (LDL-C) and risk of coronary heart disease (CHD). In order to reduce CHD risk, the National Cholesterol Education Program (NCEP) has identified LDL-C goals that can be achieved through ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.3810/pgm.04.2003.suppl26.137

    authors: Eisenberg DA

    更新日期:2003-04-01 00:00:00

  • New concepts in treatment of chronic persistent asthma. Using a stepwise protocol to control inflammation.

    abstract::Asthma continues to cause unacceptably high rates of disability and death, largely because the severity of disease is underestimated and patients are inadequately educated about their disease. When patients understand what happens during an asthma attack and its aftermath, they are more likely to notice important symp...

    journal_title:Postgraduate medicine

    pub_type: 指南,杂志文章,评审

    doi:10.1080/00325481.1991.11701034

    authors: Rumbak MJ

    更新日期:1991-09-01 00:00:00

  • Immunologically mediated lung diseases. Extrinsic allergic alveolitis and allergic bronchopulmonary aspergillosis.

    abstract::Early recognition and treatment of immunologically mediated diseases of the lung are vital to prevent irreparable damage. Extrinsic allergic alveolitis and allergic bronchopulmonary aspergillosis are often confused but should not be difficult to distinguish. The former is nonatopic and is marked by chills, fever, ches...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1976.11714331

    authors: Slavin RG

    更新日期:1976-04-01 00:00:00

  • Prescription omega-3-acid ethyl esters for the treatment of very high triglycerides.

    abstract::Triglyceride (TG) levels can increase for numerous reasons, including a sedentary lifestyle, an unhealthy diet, especially one rich in refined carbohydrates, and comorbidities. According to the National Cholesterol Education Program (NCEP), the normal TG level is < 150 mg/dL. Patients with very high TG (VHTG) levels (...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2009.07.2020

    authors: Sadovsky R,Kris-Etherton P

    更新日期:2009-07-01 00:00:00

  • Are tolerability concerns a class effect of beta-blockers in treating patients with hypertension?

    abstract::Beta-blockers (beta-blockers) have demonstrated their value across the cardiovascular disease spectrum. Beta-blockers effectively lower blood pressure in patients with hypertension and provide symptomatic or mortality benefits in patients with heart failure and in post-myocardial infarction patients. However, despite ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2009.01.1951

    authors: Kountz DS

    更新日期:2009-01-01 00:00:00

  • Problems+Solutions.

    abstract::Readers are invited to submit questions relating to problem cases. Inquiries will be answered by qualified consultants and replies forwarded by mail promptly. Selected problems and solutions are published every month in this section. ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1985.11698867

    authors: Spitzer AR,Berberian DA,Moe JH

    更新日期:1985-02-01 00:00:00

  • Combination treatment with atorvastatin plus niacin provides effective control of complex dyslipidemias: a literature review.

    abstract::Patients with dyslipidemia receive a cardiovascular benefit from lowering low-density lipoprotein cholesterol (LDL-C). Atorvastatin is currently one of the most effective approved medications for lowering LDL-C, and has been shown to significantly reduce cardiovascular risk in many patient groups. However, even with s...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2012.01.2513

    authors: McKenney JM

    更新日期:2012-01-01 00:00:00

  • Differential diagnosis of jaundice. Hepatocellular versus obstructive disease.

    abstract::The patient with jaundice may be accurately diagnosed through clinical history, physical findings, and noninvasive laboratory and radiologic examinations available in most community hospitals. Ultrasonography is usually the procedure of choice in initial evaluation, but if acute cholecystitis is suspected, hepatobilia...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:

    authors: Marin GA

    更新日期:1987-01-01 00:00:00

  • Drug therapy for congestive heart failure. Appropriate choices can prolong life.

    abstract::The goals of therapy for congestive heart failure (CHF) are to improve quality of life and to prolong it. Improvement in patients with CHF can only be realized, however, if a multidisciplinary healthcare team can provide effective management in both the inpatient and outpatient settings. Inhibition of compensatory mec...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.1997.01.143

    authors: Sorrentino MJ

    更新日期:1997-01-01 00:00:00

  • Postpartum mood disorders. A startling contrast to the joy of birth.

    abstract::More than half of new mothers may be affected by mood disorders after childbirth. Possible causes and recommended management depend on the type of disorder and its severity. In this article, Dr Knops discusses recognition, prevention, and management of three types of postpartum mood disorders as well as the need for s...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1993.11701624

    authors: Knops GG

    更新日期:1993-02-15 00:00:00

  • Drug-induced jaundice. An uncommon but puzzling reaction.

    abstract::Drug-induced jaundice is relatively uncommon but can be a diagnostic puzzle. Because so many pharmaceutical classes and individual agents can produce jaundice, a thorough history of medications taken should be obtained from a patient presenting with jaundice. Jaundice usually resolves when the offending agent is disco...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1988.11700445

    authors: Garabedian-Ruffalo SM,Ruffalo RL

    更新日期:1988-10-01 00:00:00

  • Higher pneumococcal disease vaccination rates needed to protect more at-risk US adults.

    abstract::Pneumococcal disease, which includes pneumococcal pneumonia, meningitis, and bacteremia, is associated with substantial morbidity, mortality, and health care costs in adults. Advanced age, chronic lung or cardiovascular disease, immunosuppressive conditions, and smoking increase the risk for infection. Despite the ava...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.3810/pgm.2009.11.2069

    authors: Rehm SJ,Farley MM,File TM Jr,Hall WJ,Hopkins R,Levine OS,Nichol KL,Nuorti P,Zimmerman RK,Schaffner W

    更新日期:2009-11-01 00:00:00

  • When bleeding complicates oral anticoagulant therapy. How to anticipate, investigate, and treat.

    abstract::With use of the International Normalized Ratio (INR), physicians can accurately assess the intensity of anticoagulation in treatment programs and trials. Bleeding is the major complication of oral anticoagulant therapy, and its incidence can be lessened, with no loss of efficacy, by using less intense therapy (INR, 2 ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Brigden ML

    更新日期:1995-09-01 00:00:00

  • Serologic tests for syphilis.

    abstract::Not since the early 1950s has the number of new cases of syphilis been as high as it is now. The infectious agent, Treponema pallidum, is extremely difficult to culture in vitro and almost impossible to see by conventional light microscopy. A nonspecific antibody test is used for screening and a specific treponemal an...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1990.11704578

    authors: Farnes SW,Setness PA

    更新日期:1990-02-15 00:00:00

  • Hyperlipidemia. What is 'normal,' who should be treated and how.

    abstract::Considering that over half of Americans will die from cardiovascular disease, the over-whelming majority of those deaths being from atherosclerosis, we need to accept and act on the vast body of information derived from investigation of coronary risk factors. Identification of persons at risk needs to be done early--w...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1984.11698776

    authors: Glatter TR

    更新日期:1984-11-01 00:00:00

  • Management of heart transplant recipients: reference for primary care physicians.

    abstract::Heart transplantation is the treatment of choice for a select group of patients with end-stage heart failure. Survival rates have increased and complication rates have decreased due to better immunosuppressive agents, improvement in organ procurement and surgical technique, and overall increase in experience for perfo...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2012.07.2563

    authors: Kansara P,Kobashigawa JA

    更新日期:2012-07-01 00:00:00

  • The coughing child. A primary care perspective.

    abstract::Cough in children, even in infants under 1 year of age, is a frequent problem in clinical practice. Many causes are possible and should be considered, but only a few are likely. In primary care, appropriate evaluation is based on skillful history taking. In an ostensibly healthy child or infant with recurrent episodes...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1983.11698430

    authors: Schneider AP 2nd,Daws WR,Adams RD

    更新日期:1983-09-01 00:00:00

  • Evaluation of lorcaserin on progression of prediabetes to type 2 diabetes and reversion to euglycemia.

    abstract:OBJECTIVES:Lorcaserin is a selective 5-HT2C (5-hydroxytryptamine 2C) receptor agonist indicated for weight management. Here, we assess the impact of lorcaserin on progression from prediabetes to type 2 diabetes (T2D) and on reversion from prediabetes to euglycemia. METHODS:This is a post hoc analysis of pooled data fr...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.2016.1178590

    authors: Nesto R,Fain R,Li Y,Shanahan W

    更新日期:2016-05-01 00:00:00

  • Evidence-based therapy for type 2 diabetes. The best and worst of times.

    abstract::Type 2 diabetes, which is increasing in prevalence, is a multifaceted disease that presents a challenge to the primary care physician. In this article, Drs Flemmer and Vinik review the significant findings of several important clinical trials and present a method of comprehensive staged management to improve the quali...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2000.5.1.1064

    authors: Flemmer MC,Vinik AI

    更新日期:2000-05-01 00:00:00

  • Helping patients who say they cannot sleep. Practical ways to evaluate and treat insomnia.

    abstract::Why do some people spend most of the night tossing and turning while others drop off as quickly as a cat in the sun? There are many possible explanations for problems with falling and staying asleep and, sometimes, patients actually get a lot more sleep than they think they do. Each type of insomnia has its own set of...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2000.03.935

    authors: Attarian HP

    更新日期:2000-03-01 00:00:00

  • Common disorders of pigmentation: when are more than cosmetic cover-ups required?

    abstract::The many types of pigmentation disorders may present in diverse forms and distributions and have various causes. They can be inherited (eg, vitiligo, familial periorbital hyperpigmentation), acquired (eg, postinflammatory pityriasis alba, idiopathic guttate hypomelanosis, Becker's nevus, melasma), infectious (eg, tine...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:

    authors: Hacker SM

    更新日期:1996-06-01 00:00:00

  • patient notes index.

    abstract::Patient Notes are indexed alphabetically and by subject. The number immediately following the title is the number of the Patient Note, and the number in parentheses is the date of publication. This index includes all 82 Patient Notes published so far, from February 1, 1988, through this issue. ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1993.11701589

    authors:

    更新日期:1993-01-01 00:00:00

  • A primary care approach to Sjögren's syndrome. Helping patients cope with sicca symptoms, extraglandular manifestations.

    abstract::Sjögren's syndrome is a chronic, systemic, autoimmune inflammatory disorder characterized by lymphocytic infiltration of exocrine glands, most notably the salivary and lacrimal glands. It results in loss of functional epithelium, diminished exocrine function, and gradual onset of dryness of the eyes, mouth, and other ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2004.09.1587

    authors: Derk CT,Vivino FB

    更新日期:2004-09-01 00:00:00

  • Laboratory tests for rheumatic diseases.

    abstract::A carefully taken history and thorough physical examination remain the most crucial aspects of diagnosing rheumatic disorders. Non-rheumatologic conditions also need to be kept in mind. Laboratory tests should be looked on as mostly supportive or confirmatory, because many of the tests are relatively nonspecific and m...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.1080/00325481.1991.11700818

    authors: Yancey WB Jr,Williams RC Jr

    更新日期:1991-02-01 00:00:00

  • Chronic hepatitis B: perceptions in Asian American communities and diagnosis and management practices among primary care physicians.

    abstract:BACKGROUND:Asian Americans exhibit a high prevalence of chronic hepatitis B (CHB) compared with the general population in the United States. However, there are specific barriers to appropriate health care in the Asian American population, and CHB awareness is low. The aim of this study was to examine CHB awareness amon...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.3810/pgm.2010.09.2213

    authors: Upadhyaya N,Chang R,Davis C,Conti MC,Salinas-Garcia D,Tang H

    更新日期:2010-09-01 00:00:00

  • Oral steroids in rheumatoid arthritis. Helpful but not remittive.

    abstract::Although low-dose oral corticosteroid therapy cannot be considered remittive, it has earned a place in the therapeutic armamentarium for rheumatoid arthritis. Major clinical trials of a group using corticosteroid compared with a control group have not been done since the 1950s. One of these three large trials showed s...

    journal_title:Postgraduate medicine

    pub_type: 临床试验,杂志文章,评审

    doi:10.1080/00325481.1987.11700016

    authors: Iannuzzi LP

    更新日期:1987-10-01 00:00:00

  • Pain management in primary care: strategies to mitigate opioid misuse, abuse, and diversion.

    abstract::Pain is among the most common reasons patients seek medical attention, and the care of patients with pain is a significant problem in the United States. Acute pain (mild-to-moderate intensity) represents one of the most frequent complaints encountered by primary care physicians (PCPs) and accounts for nearly half of p...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审

    doi:10.3810/pgm.2011.03.2270

    authors: McCarberg BH

    更新日期:2011-03-01 00:00:00

  • Hematuria. When is it cause for alarm?

    abstract::The urine of less than 3% of healthy persons shows more than three red cells per high-power field, which is about the limit of sensitivity of test strips for occult blood. Even minimal hematuria may herald serious problems and must be investigated. Common causes include infection, urethritis, and urethrotrigonitis (25...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1987.11699979

    authors: Brown DC

    更新日期:1987-09-15 00:00:00

  • Mycobacterium chimaera chorioretinitis as a biomarker of systemic disease activity following nosocomial acquisition during cardiopulmonary bypass.

    abstract::Objectives: To understand the role of ophthalmoscopic examination (dilated retina examination and widefield fundus photography) in the diagnosis and management of nosocomial acquisition of Mycobacterium chimaera following open heart surgery with cardiopulmonary bypass utilizing a heater-cooler unit, an entity that is ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.2019.1697545

    authors: Colucciello M

    更新日期:2020-03-01 00:00:00

  • The new hepatitis B vaccine. How, when, and why to use it.

    abstract::A hepatitis B vaccine derived from the plasma of carriers of hepatitis B virus has recently become generally available in the United States. Its use is recommended in groups considered to be at high risk of hepatitis B because of their exposure to potentially infectious blood, saliva, or semen. Experience in more than...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章

    doi:10.1080/00325481.1983.11697828

    authors: Kutcher WL

    更新日期:1983-05-01 00:00:00