Drug-induced jaundice. An uncommon but puzzling reaction.


:Drug-induced jaundice is relatively uncommon but can be a diagnostic puzzle. Because so many pharmaceutical classes and individual agents can produce jaundice, a thorough history of medications taken should be obtained from a patient presenting with jaundice. Jaundice usually resolves when the offending agent is discontinued.


Postgrad Med


Postgraduate medicine


Garabedian-Ruffalo SM,Ruffalo RL




Has Abstract


1988-10-01 00:00:00


205-10, 213










  • Health care provider management of patients with type 2 diabetes mellitus: analysis of trends in attitudes and practices.

    abstract:OBJECTIVE:To identify attitudes and practices of endocrinologists (ENDOs), family practitioners (FPs), internists (IMs), primary care nurse practitioners (NPs), physician assistants (PAs), certified diabetes educators (CDEs), retail pharmacists (R-PHs), and hospital pharmacists (H-PHs) with respect to type 2 diabetes m...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章


    authors: Williamson C,Glauser TA,Burton BS,Schneider D,Dubois AM,Patel D

    更新日期:2014-05-01 00:00:00

  • Moderate Parkinson's disease. Strategies for maximizing treatment.

    abstract::Motor fluctuations and dyskinesia often develop in patients with Parkinson's disease after 3 to 5 years of levodopa therapy. Dosage adjustments, addition of a second medication to the drug regimen, and dietary modifications may help maximize response to symptomatic therapy. Given the dramatic variability of symptoms a...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审


    authors: Silverstein PM

    更新日期:1996-01-01 00:00:00

  • Evidence-based therapy for type 2 diabetes. The best and worst of times.

    abstract::Type 2 diabetes, which is increasing in prevalence, is a multifaceted disease that presents a challenge to the primary care physician. In this article, Drs Flemmer and Vinik review the significant findings of several important clinical trials and present a method of comprehensive staged management to improve the quali...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审


    authors: Flemmer MC,Vinik AI

    更新日期:2000-05-01 00:00:00

  • Drug management of stable angina pectoris.

    abstract::Nitroglycerin and long-acting nitrates are the pharmacologic mainstays of antianginal therapy, both for acute attacks and for prophylaxis. Propranolol is often effective for prophylaxis in patients incompletely helped by nitrates. A holistic approach is stressed. Appropriate drug use will effect marked improvement in ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章


    authors: Richtsmeier TE,Preston TA

    更新日期:1977-11-01 00:00:00

  • Benign essential tremor: features that aid in diagnosis.

    abstract::Benign essential tremor can be distinguished from parkinsonism by its rapid frequency, the involvement of voice and head, and the common finding of a positive family history. Essential tremor is less incapacitating than parkinsonism and less inexorably progressive. Propranolol (Inderal) is the best therapy available a...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章


    authors: Paulson GW

    更新日期:1982-01-01 00:00:00

  • Evaluation of involuntary weight loss. Where do you start?

    abstract::When a patient presents with involuntary weight loss, the etiologic considerations can be overwhelming. To plan a cost-effective workup, physicians need to be aware of the most common causes of weight loss and the tests that yield the most pertinent data. Drs Wise and Craig review the clinical studies on unintentional...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审


    authors: Wise GR,Craig D

    更新日期:1994-03-01 00:00:00

  • Lymphedema of the limb. An overview of treatment options.

    abstract::In developed countries, prevalence is increasing of malignancy-related secondary lymphedema, usually resulting from lymph node resection or irradiation. Untreated lymphedema usually increases over time, and the physical and psychological sequelae in even mild cases demand appropriate diagnosis and treatment. Patients ...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审


    authors: Tunkel RS,Lachmann E

    更新日期:1998-10-01 00:00:00

  • Hyperlipidemia. What is 'normal,' who should be treated and how.

    abstract::Considering that over half of Americans will die from cardiovascular disease, the over-whelming majority of those deaths being from atherosclerosis, we need to accept and act on the vast body of information derived from investigation of coronary risk factors. Identification of persons at risk needs to be done early--w...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章


    authors: Glatter TR

    更新日期:1984-11-01 00:00:00

  • Management of diabetes in patients with chronic kidney disease.

    abstract::Management of patients with diabetes mellitus and chronic kidney disease (CKD) is a challenging task because multiple factors in each condition may impact the other. Glycemic control offers significant benefits in the prevention of diabetic kidney disease (DKD), but other associated morbidities are also important to a...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审


    authors: Ahmed Z,Simon B,Choudhury D

    更新日期:2009-05-01 00:00:00

  • Migraine headache. Working for the best outcome.

    abstract::Migraine is a common hereditary disorder manifested by episodic headache, irritability, and gastrointestinal upset. The condition may be triggered by dietary, environmental, psychological, or pharmacologic factors. With proper diagnosis and judicious use of abortive and prophylactic therapy, patients often obtain exce...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章


    authors: Diamond S,Freitag FG,Solomon GD,Millstein E

    更新日期:1987-06-01 00:00:00

  • Exercise-induced asthma.

    abstract::Exercise-induced asthma can appear as one of many forms of airway hyperreactivity or as a unique clinical entity. Simple spirometry confirms the suspected clinical diagnosis in most instances, although more sensitive measurements of airway obstruction may be required. In general, the asthmatic need not restrict physic...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章


    authors: Gerhard H,Schachter EN

    更新日期:1980-03-01 00:00:00

  • Efficacy and safety of saxagliptin combination therapy in US patients with type 2 diabetes.

    abstract:BACKGROUND:The mechanism of action of dipeptidyl peptidase-4 inhibitors, such as saxagliptin, makes them suitable for combination therapy in type 2 diabetes mellitus (T2DM). Genetic, cultural, and environmental differences in individuals from different regions of the world may result in differences in treatment respons...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,多中心研究,随机对照试验


    authors: Karyekar C,Donovan M,Allen E,Fleming D,Ravichandran S,Chen R

    更新日期:2011-07-01 00:00:00

  • Rheumatoid arthritis. Targeted interventions can minimize joint destruction.

    abstract::Rheumatoid arthritis can cause joint erosion and deformity, pain, stiffness, and decreased function and range of motion. Early diagnosis is crucial to prevent permanent joint damage. In this article, Drs Williams and Fye discuss articular and extra-articular manifestations of rheumatoid arthritis as well as the evolvi...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审


    authors: Williams EA,Fye KH

    更新日期:2003-11-01 00:00:00

  • Rheumatic diseases. 1. Differential diagnosis.

    abstract::In a case of rheumatic disease, the patient's history and a careful physical examination should yield most of the information needed to identify the specific disorder present. A convenient classification is based on four differentiating features: number of joints affected, acuteness or chronicity of disease, absence o...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章


    authors: Weiss TE,Gum OB,Biundo JJ Jr

    更新日期:1976-12-01 00:00:00

  • Superficial and cutaneous fungal infections: diagnosis and treatment.

    abstract::Fungal infections usually have characteristics that make them easily identifiable. In most cases, clinical diagnosis can be readily confirmed by examining the lesions under Wood's light or by placing infected material in potassium hydroxide solution and examining the preparation microscopically. Dermatophytes can be r...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章


    authors: Millikan LE

    更新日期:1976-07-01 00:00:00

  • Role of primary care physicians in intrathecal pain management: a narrative review of the literature.

    abstract:OBJECTIVES:The majority of patients seeking medical care for chronic pain consult a primary care physician (PCP). Because systemic opioids are commonly prescribed to patients with chronic pain, PCPs are attempting to balance the competing priorities of providing adequate pain relief while reducing risks for opioid misu...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审


    authors: McDowell GC 2nd,Winchell J

    更新日期:2018-05-01 00:00:00

  • The aging process.

    abstract::Preview Although no one theory on aging explains satisfactorily why or how this process occurs, we know that aging causes physiologic changes and a progressive decline of functional organ reserve. The implications of these changes are increasingly important as the elderly segment of the population grows. In this artic...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章


    authors: Troncale JA

    更新日期:1996-05-01 00:00:00

  • Cancer of the colon and rectum. A review.

    abstract::Colonic cancer remains a major cause of death because diagnosis is usually delayed. Improved methods for earlier detection will maximize the patient's chances for survival. At present, surgery offers the greatest possibility of cure, but even in those instances where less than definitive resection is possible, there i...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章


    authors: Wallack MK,Rosato FE,Brown AS,Rosato EF

    更新日期:1975-04-01 00:00:00

  • Epistaxis packing. Practical pointers for nosebleed control.

    abstract::Primary care physicians often encounter epistaxis. Its treatment may involve nasal sponge tampons, double-balloon nasal catheters, and anterior gauze with posterior Foley catheters, depending on the location of the bleed. Topical anesthetic and decongestant agents are essential, and intravenous analgesia, which enhanc...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审


    authors: Randall DA

    更新日期:2006-06-01 00:00:00

  • Thromboembolism during pregnancy. Risks, challenges, and recommendations.

    abstract::Pregnancy is an important risk factor for venous thrombosis, and venous thromboembolism is a leading cause of preventable death in pregnancy. Diagnosis of venous thromboembolism is complicated in that the symptoms of dyspnea and lower extremity edema are relatively common complaints of pregnant patients. Physicians sh...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审


    authors: Sellman JS,Holman RL

    更新日期:2000-09-15 00:00:00

  • Evaluation of a first seizure. Is it epilepsy?

    abstract::The first step in evaluation of a presumed seizure is to determine whether the event was indeed a seizure and which diagnostic studies are needed. The second step is to correctly diagnose the seizure on the basis of the medical history and findings from the physical, neurologic, and laboratory evaluation. The third st...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审


    authors: Prego-Lopez M,Devinsky O

    更新日期:2002-01-01 00:00:00

  • Efficacy and tolerability of long-term venlafaxine XR therapy for GAD. Results of long-term, double-blind, placebo-controlled studies.

    abstract::Various antidepressants and anxiolytic agents have proved to be effective as short-term therapy for generalized anxiety disorder (GAD) and other anxiety disorders. However, less is known about their efficacy in the long-term treatment of GAD. This gap in our knowledge poses a problem for physicians, who treat GAD over...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,随机对照试验


    authors: Lydiard RB

    更新日期:1999-11-01 00:00:00

  • The solitary pulmonary nodule. Is it malignant or benign?

    abstract::Solitary pulmonary nodules are usually identified on routine chest radiographs in asymptomatic patients. Most nodules have a benign cause, but bronchogenic carcinoma, metastases, and other malignant processes are important causes as well and must be excluded in differential diagnosis. Plain chest radiography, computed...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审


    authors: Dholakia S,Rappaport DC

    更新日期:1996-02-01 00:00:00

  • Human insulin. Its development and clinical use.

    abstract::With the recent availability of human insulin, we have entered a new era in therapy for diabetes mellitus. Human insulin is not a cure for diabetes; however, no disadvantages are known to be associated with its use at present. Human insulin costs less than the other purified insulins, and because of its potential adva...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审


    authors: Ahrens ER,Gossain VV,Rovner DR

    更新日期:1986-07-01 00:00:00

  • Gastric volvulus. More common than previously thought?

    abstract::Gastric volvulus is torsion of the stomach, which can compromise the gastric orifices and result in either acute or chronic and intermittent symptoms. We believe that gastric volvulus, especially when partial or intermittent, may be more common than has been previously thought. The condition should be suspected in any...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章


    authors: Llaneza PP,Salt WB 2nd

    更新日期:1986-10-01 00:00:00

  • Theophylline therapy. Titrating dosage requirements.

    abstract::Theophylline has long been a cornerstone of bronchodilator therapy for asthma and chronic obstructive lung disease, but until recently its use carried the risk of serious, even fatal, toxicity. With recent advances in understanding of this drug's pharmacologic properties and pharmacokinetic characteristics, serious to...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章


    authors: Uden DL,Wyatt RA,Zaske DE

    更新日期:1984-06-01 00:00:00

  • Proteinuria. How much evaluation is appropriate?

    abstract::Primary care physicians play an important role in the outpatient evaluation of proteinuria, a common finding in everyday medical practice. Therefore, it is important to recognize which symptoms and signs signal the need for further evaluation. A simple urine dipstick test usually is the first step, but factors leading...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审


    authors: Ali H

    更新日期:1997-04-01 00:00:00

  • Gallstone symptoms. Myth and reality.

    abstract::Gallstones are very common, but at least two thirds of detected stones are asymptomatic and a large number undoubtedly go undetected. The presence of symptoms or complications is the indication for surgery. It is important to accurately identify which symptoms are caused by gallstones, because removing the gallbladder...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章


    authors: Egbert AM

    更新日期:1991-10-01 00:00:00

  • Bronchiectasis in adults: a review.

    abstract::Bronchiectasis is characterized by permanent, abnormal dilation of the bronchi with chronic inflammation and infection. Bronchiectasis is either caused by or associated with several systemic disorders, and in a significant number of cases, the underlying etiology remains unidentified and is subsequently referred to as...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章,评审


    authors: Lazarus A,Myers J,Fuhrer G

    更新日期:2008-09-01 00:00:00

  • Special aspects of primary care.

    abstract::Common dislocations that can usually be managed in the office include anterior dislocations of the shoulder, posterior dislocations of the elbow and joints of the fingers and toes, and lateral dislocations of the patella. A systematic approach based on an understanding of the mechanism of injury, roentgenographic docu...

    journal_title:Postgraduate medicine

    pub_type: 杂志文章


    authors: Huffer JM

    更新日期:1977-11-01 00:00:00