Abstract：
:The thrifty genotype hypothesis was proposed by Neel in 1962 to explain the increasing incidence of diabetes in the western world. Since then it has been invoked frequently to explain the epidemics of obesity and non-insulin dependent diabetes (NIDDM) in populations all over the world as they have made the rapid transition to a westernised lifestyle in the twentieth century. An examination of the archaeological record indicates that human populations were exposed to nutritional stresses throughout history (both as hunter-gatherers and agriculturalists) which could have selected strongly for a "thrifty" metabolism. The metabolic basis of the "thrifty" genotype has been attributed to selective insulin resistance, in which the gluco-regulatory pathways of insulin action are affected primarily, thereby promoting compensatory hyperinsulinaemia and overstimulation of those pathways less affected by insulin resistance such as those involved in fat deposition. Both physical inactivity and an energy-dense diet high in saturated fat and fibre-depleted carbohydrate have been shown to increase insulin resistance. Thus, key components of the western lifestyle act to exacerbate insulin resistance and facilitate weight gain, which itself also worsens insulin resistance. Finally, Hales and Barker have argued provocatively for a "thrifty" phenotype as the major predisposing factor in NIDDM: that poor nutrition in the perinatal period is associated with increased risk of NIDDM in adulthood, mediated either through sustained effects on b -cell function or insulin sensitivity. The difficulties in differentiating between "nature" and "nurture" in the aetiology of this complex condition cannot be overstated.
journal_name
Asia Pac J Clin Nutrjournal_title
Asia Pacific journal of clinical nutritionauthors
O'Dea Ksubject
Has Abstractpub_date
1995-12-01 00:00:00pages
339-40issue
4eissn
0964-7058issn
1440-6047journal_volume
4pub_type
杂志文章abstract：OBJECTIVES:Vitamin B-12 and n-3 polyunsaturated fatty acids (PUFA) decrease blood homocysteine (Hcy) concentrations. However, the combined effect of these nutrients on Hcy and ferritin, and C-reactive protein is limited and inconclusive. The objective was to examine the synergistic effect of vitamin B-12 in combination...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.6133/apjcn.2015.24.3.19
更新日期：2015-01-01 00:00:00
abstract：:We examined the plasma levels of carotenoids in young adults after a dietary intervention composed of increased intakes of fruits and stir-fried vegetables from a Taiwanese mixed diet. Thirty-four apparently healthy, non-smoking subjects who normally ingested less than two and a half servings of fruits and vegetables ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,随机对照试验
doi：
更新日期：2007-01-01 00:00:00
abstract：:Dietary guidelines based on 5 food groups was used as a main nutrition education tool until 1996 when food based dietary guidelines (FBDGs) were promoted after 2 years of formulation and development. These FBDGs for the general population were designed to promote desirable and culturally acceptable eating behavior. Th...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：2011-01-01 00:00:00
abstract：:The objective is to present the case of a 21-yr-old athlete observed with non-physiological immediate postprandial insulin response (1162 pmol/l; normal glucose excursion: 6.6 mmol/l), in a warm environment. No suspicion or evidence of any underlying pathology was found in this well-trained Afro-Caribbean male runner....
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.052017.10
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:There is very limited published data on Tibetan dietary patterns and its association with nutrient intakes and socioeconomic factors. The aim of this study was to identify and describe the dietary patterns and the associations with nutrient intakes in rural Tibetan pregnant, lactating mothers....
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.012016.13
更新日期：2017-05-01 00:00:00
abstract：:Many studies in Asia have demonstrated that Asian populations may require lower cut-off levels for body mass index (BMI) and waist circumference to define obesity and abdominal obesity respectively, compared to western populations. Optimal cut-off levels for body mass index and waist circumference were determined to a...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2009-01-01 00:00:00
abstract：:Bacterial antagonism has been recognised for over a century but in recent years this phenomenon has received more scientific attention, particularly in the use of various strains of lactic acid bacteria (LAB). Antimicrobial compounds produced by LAB have provided these organisms with a competitive advantage over other...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1996-03-01 00:00:00
abstract：:Item non-responses are frequently encountered in mailed food frequency questionnaires (FFQs) in epidemiological studies. The effects of item non-responses in a FFQ on presumed nutrient intake and subject classifications were examined in this study of a male cancer cohort in Korea. A semi-quantitative FFQ was developed...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2006-01-01 00:00:00
abstract：:Recent data indicate a rise in obesity both in children and adolescents in developing countries. The overall prevalence of overweight/obesity in urban children in New Delhi has shown an increase from 16% in 2002 to about 24% in 2006-2007. Our recent data show that the prevalence among adolescent children was 29% in pr...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：
更新日期：2008-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:The consumption of unhealthy snack and beverages can lead to childhood obesity, which has become a major concern globally. Television food advertisements may influence children's snack and beverages preferences. This article aims to explore children's snack and beverage consumption habits; exa...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.012017.04
更新日期：2017-01-01 00:00:00
abstract：:Stress and malnutrition are associated with altered body composition. Extracellular fluid increases, with wt gain, but in response to stress BCM may gradually shrink with wt loss. In catabolic illness there is extracellular fluid expansion and erosion of AT and BCM. In stress, net loss of body fat was associated with ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1995-03-01 00:00:00
abstract：:This study explored the association between dietary habits and overweight and obesity in adolescents from Xi'an City, China. A cross-sectional sample of 1804 adolescents was recruited in 2004 from 30 junior high schools in six districts of Xi'an City, northwest China. Weight and height was measured and eating habits a...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2010-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:This study aimed to assess the influence of prolonged preoperative fasting on prognosis in elective surgery. METHODS AND STUDY DESIGN:A retrospective, controlled study involving patients admitted to our surgical intensive care unit who underwent a gastrointestinal operation under general anes...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.202003_29(1).0006
更新日期：2020-01-01 00:00:00
abstract：:The Asia-Pacific region is undergoing a major change in both food and health patterns, with a connection between the two more than likely. Evidence for certain traditional Asia-Pacific foods as protective agents against chronic non-communicable disease and cardiovascular disease (CVD), in particular, is growing at a t...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章,评审
doi：10.1111/j.1440-6047.2001.00234.x
更新日期：2001-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:In the United States, synthetic folic acid has become an important source of folate in the era of mandatory folic acid fortification. This study aimed to evaluate the associations between total folate, natural folate and synthetic folic acid intakes and depressive symptoms among US adults. ME...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.202012_29(4).0021
更新日期：2020-01-01 00:00:00
abstract：:The present study was undertaken in two backward districts namely Phulbani and Sundargarh, of Orissa State, India, to study operational aspects of the distribution programme of iron fortified salt (IFS), and the extent of any overlap with the ongoing National Nutritional Anaemia Control Programme (NNACP) and possible ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1992-12-01 00:00:00
abstract：:Australia New Zealand Food Authority (ANZFA) is a bi-national government agency forming a partnership between all of Australia's States and Territories and the New Zealand government. Australia New Zealand Food Authority employs scientific, legal policy, communication and administrative staff in our Australia and New ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.1046/j.1440-6047.2002.00002.x
更新日期：2002-01-01 00:00:00
abstract：:Hypertension, an important risk factor for coronary heart disease (CHD), is often associated with certain dietary habits which can either adversely affect or decrease blood pressure. Several Western studies have documented the role of diet, especially excess energy, both quality and quantity of fat and salt, in the ae...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.1046/j.1440-6047.1999.00092.x
更新日期：1999-09-01 00:00:00
abstract：:Hair mineral analysis using an X-ray fluorescence spectrometer as a method of estimating body fat percentage (BF%) was investigated. Body fat percentage of 24 healthy Japanese, aged 20-27 years, was measured using a hand-held impedance analyzer (BF%IMP). X-ray (Kα-ray) intensities of sulfur, chlorine, potassium, calci...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.2013.22.2.14
更新日期：2013-01-01 00:00:00
abstract：:This survey was initiated to examine possible coastal-inland differences in cadmium (Cd) burden in general Korean populations. In total, 268 healthy non-smoking middle-aged women (30 to 49 years; 88 residents in 8 coastal areas and 180 residents in 15 inland areas) participated in the study. They offered peripheral bl...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.2014.23.2.10
更新日期：2014-01-01 00:00:00
abstract：OBJECTIVE:To investigate the predictive value of high body mass index (H-BMI) on the survival of patients with esophageal cancer (EC) after curative esophagectomy. METHODS:Studies were systematically identified to investigate the relationship between overweight and obese (H-BMI) and clinical outcomes in EC patients tr...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.2015.24.3.05
更新日期：2015-01-01 00:00:00
abstract：:A knowledge-attitude-practices (KAP) study was conducted along with a prevalence study of iodine deficiency disorders (IDD) between 1998-99 in the district of Bargarh, Orissa state, India. A total of 635 people were interviewed by a pretested structured questionnaire, adopting the probability proportional to size clus...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.1046/j.1440-6047.2001.00203.x
更新日期：2001-01-01 00:00:00
abstract：:The evolution of nutritional status (the prevalence of nutritional risk, malnutrition, overweight and obesity) and the nutritional support of the hospitalized patients from admission to discharge or over a two-week period in orthopedics/ spinal surgery of a teaching hospital in Hohhot were investigated. 432 patients f...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.2016.25.2.26
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Head and neck cancer patients often experience nutritional deterioration, which decreases their treatment tolerance and is associated with poor outcomes. We analyzed nutritional status in head and neck cancer patients before and during treatment, and its impact on clinical outcomes. METHODS A...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.201906_28(2).0003
更新日期：2019-01-01 00:00:00
abstract：:It has been well acknowledged that Vietnam is undergoing a nutrition transition. With a rapid change in the country's reform and economic growth, food supply at the macronutrient level has improved. Changes of the Vietnamese diet include significantly more foods of animal origin, and an increase of fat/oils, and ripe ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2008-01-01 00:00:00
abstract：:A computer system, called SERVE-NZ Nutririon Management System, for use in diabetes management, addresses the problem of concurrently controlling postprandial glycaemic response and nutrient intake in meals containing a number of foods, is described. It converts the weight and relative glycaemic potency of each food t...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.1046/j.1440-6047.2000.00146.x
更新日期：2000-06-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Mechanically ventilated patients often face progressive and rapid losses of body mass and muscle because of hypermetabolism and increased protein catabolism. To investigate the impact of adequate nutritional provision during the early phase of intensive care unit (ICU) admission on the clinica...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.032016.01
更新日期：2017-03-01 00:00:00
abstract：:To evaluate the validity of habitual marine fish intake, the relation between fatty acid composition of serum phospholipids and dietary patterns were investigated. Dietary intake and serum fatty acid concentrations were measured in healthy subjects of coastal fish consuming and non-fish consuming populations. Amongst ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：1997-12-01 00:00:00
abstract：BACKGROUND AND OBJECTIVES:Preschool undernutrition remains a burden in Nepal. This paper reports results of surveys in 2013 and 2014, examining patterns of child nutritional status across the country, associations with household food insecurity and antecedent comparative national data for subsequent evaluations of nutr...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：10.6133/apjcn.092017.04
更新日期：2018-01-01 00:00:00
abstract：:Thickening agents, such as carob bean gum or galactomannan, have been successfully administered for the treatment of gastroesophageal reflux in infants. To study the effect of carob bean gum on gastric emptying and to symptoms of regurgitation, we recruited 20 full term Thai infants (mean age=13.4+/-7 week; mean body ...
journal_title：Asia Pacific journal of clinical nutrition
pub_type： 杂志文章
doi：
更新日期：2003-01-01 00:00:00
